Dr. rer. nat. Bernhard Schmidt

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  • 2019 | Journal Article
    ​ ​Protein disulfide isomerase is a possible target for disease modification in multiple sulfatase deficiency​
    Schlotawa, L.; Wachs, M.; Bernhard, O. ; Mayer, F. J.; Dierks, T.; Schmidt, B.   & Radhakrishnan, K.​ (2019) 
    Molecular Genetics and Metabolism, 126(2) pp. S131​-S132​.​ DOI: https://doi.org/10.1016/j.ymgme.2018.12.338 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Recognition and ER Quality Control of Misfolded Formylglycine-Generating Enzyme by Protein Disulfide Isomerase​
    Schlotawa, L.; Wachs, M.; Bernhard, O. ; Mayer, F. J.; Dierks, T.; Schmidt, B.   & Radhakrishnan, K.​ (2018) 
    Cell Reports, 24(1) pp. 27​-37.e4​.​ DOI: https://doi.org/10.1016/j.celrep.2018.06.016 
    ​Details  DOI 
  • 2016 | Journal Article | Research Paper
    ​ ​Cox26 is a novel stoichiometric subunit of the yeast cytochrome c oxidase​
    Levchenko, M.; Wuttke, J.-M.; Römpler, K.; Schmidt, B. ; Neifer, K.; Juris, L.   & Wissel, M.  et al.​ (2016) 
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1863(7) pp. 1624​-1632​.​ DOI: https://doi.org/10.1016/j.bbamcr.2016.04.007 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | Research Paper | 
    ​ ​Protein cofactor competition regulates the action of a multifunctional RNA helicase in different pathways​
    Heininger, A. U. ; Hackert, P. ; Andreou, A. Z.; Boon, K.-L. ; Memet, I. ; Prior, M.   & Clancy, A.  et al.​ (2016) 
    RNA Biology, 13(3) pp. 320​-330​.​ DOI: https://doi.org/10.1080/15476286.2016.1142038 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper
    ​ ​A presequence-binding groove in Tom70 supports import of Mdl1 into mitochondria​
    Melin, J. ; Kilisch, M. ; Neumann, P. ; Lytovchenko, O. ; Gomkale, R.; Schendzielorz, A. B.   & Schmidt, B.  et al.​ (2015) 
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1853(8) pp. 1850​-1859​.​ DOI: https://doi.org/10.1016/j.bbamcr.2015.04.021 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper
    ​ ​Presequence Recognition by the Tom40 Channel Contributes to Precursor Translocation into the Mitochondrial Matrix​
    Melin, J. ; Schulz, C. ; Wrobel, L.; Bernhard, O. ; Chacinska, A.; Jahn, O.   & Schmidt, B.  et al.​ (2014) 
    Molecular and Cellular Biology, 34(18) pp. 3473​-3485​.​ DOI: https://doi.org/10.1128/MCB.00433-14 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper
    ​ ​The INA complex facilitates assembly of the peripheral stalk of the mitochondrial F1Fo-ATP synthase​
    Lytovchenko, O. ; Naumenko, N. ; Oeljeklaus, S.; Schmidt, B. ; von der Malsburg, K.; Deckers, M.   & Warscheid, B. et al.​ (2014) 
    EMBO Journal, 33(15) pp. 1624​-1727​.​ DOI: https://doi.org/10.15252/embj.201488076 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Mouse Dazl and its novel splice variant functions in translational repression of target mRNAs in embryonic stem cells​
    Xu, X.; Tan, X.; Lin, Q.; Schmidt, B. ; Engel, W. & Pantakani, D. V. K. ​ (2013) 
    Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1829(5) pp. 425​-435​.​ DOI: https://doi.org/10.1016/j.bbagrm.2012.12.010 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | Research Paper | 
    ​ ​Rapid degradation of an active formylglycine generating enzyme variant leads to a late infantile severe form of multiple sulfatase deficiency​
    Schlotawa, L.; Radhakrishnan, K.; Baumgartner, M.; Schmid, R.; Schmidt, B. ; Dierks, T. & Gärtner, J. ​ (2013) 
    European Journal of Human Genetics, 21(9) pp. 1020​-1023​.​ DOI: https://doi.org/10.1038/ejhg.2012.291 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article | Research Paper
    ​ ​The Channel-Forming Sym1 Protein Is Transported by the TIM23 Complex in a Presequence-Independent Manner​
    Reinhold, R. ; Krüger, V.; Meinecke, M. ; Schulz, C. ; Schmidt, B. ; Grunau, S. D.   & Guiard, B. et al.​ (2012) 
    Molecular and Cellular Biology, 32(24) pp. 5009​-5021​.​ DOI: https://doi.org/10.1128/MCB.00843-12 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | Research Paper | 
    ​ ​Tim50's presequence receptor domain is essential for signal driven transport across the TIM23 complex​
    Schulz, C. ; Lytovchenko, O. ; Melin, J. ; Chacinska, A.; Guiard, B.; Neumann, P.   & Ficner, R.  et al.​ (2011) 
    The Journal of Cell Biology, 195(4) pp. 643​-656​.​ DOI: https://doi.org/10.1083/jcb.201105098 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article | Research Paper | 
    ​ ​SUMF1 mutations affecting stability and activity of formylglycine generating enzyme predict clinical outcome in multiple sulfatase deficiency​
    Schlotawa, L.; Ennemann, E. C.; Radhakrishnan, K.; Schmidt, B. ; Chakrapani, A.; Christen, H.-J. & Moser, H. et al.​ (2011) 
    European Journal of Human Genetics, 19(3) pp. 253​-261​.​ DOI: https://doi.org/10.1038/ejhg.2010.219 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Conference Abstract
    ​ ​FUNCTIONAL CHARACTERIZATION OF TWO NOVEL SUMF1 MUTATIONS LEADING TO A MILD PHENOTYPE IN MULTIPLE SULFATASE DEFICIENCY​
    Schlotawa, L.; Radhakrishnan, K.; Schmid, R.; Schmidt, B. ; Dierks, T.; Gaertner, J.   & Baumgartner, M.​ (2010)
    Journal of Inherited Metabolic Disease, 33 
    Dordrecht​: Springer.
    ​Details  WoS 
  • 2005 | Journal Article | Research Paper
    ​ ​Crystal structure of human pFGE, the paralog of the C alpha-formylglycine-generating enzyme​
    Dickmanns, A. ; Schmidt, B. ; Rudolph, M.; Mariappan, M.; Dierks, T.; Von Figura, K.   & Ficner, R. ​ (2005) 
    Journal of biological chemistry, 280(15) pp. 15180​-15187​.​ DOI: https://doi.org/10.1074/jbc.M414317200 
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Journal Article | Research Paper | 
    ​ ​Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme​
    Dierks, T.; Dickmanns, A. ; Preusser-Kunze, A.; Schmidt, B. ; Mariappan, M.; Von Figura, K.   & Ficner, R.  et al.​ (2005) 
    Cell, 121(4) pp. 541​-552​.​ DOI: https://doi.org/10.1016/j.cell.2005.03.001 
    ​Details  DOI  PMID  PMC  WoS 
  • 2003 | Journal Article
    ​ ​Highly conserved and disease-specific patterns of carboxyterminally truncated Aβ peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation​
    Wiltfang, J. ; Esselmann, H. ; Bibl, M. ; Smirnov, A. ; Otto, M. ; Paul, S.   & Schmidt, B.  et al.​ (2003) 
    Journal of Neurochemistry, 81(3) pp. 481​-496​.​ DOI: https://doi.org/10.1046/j.1471-4159.2002.00818.x 
    ​Details  DOI 
  • 2002 | Journal Article
    ​ ​Defective oligomerization of arylsulfatase A as a cause of its instability in lysosomes and metachromatic leukodystrophy​
    Bülow, R. von; Schmidt, B. ; Dierks, T.; Schwabauer, N.; Schilling, K.; Weber, E. & Usón, I. et al.​ (2002) 
    Journal of Biological Chemistry, 277(11) pp. 9455​-9461​.​ DOI: https://doi.org/10.1074/jbc.M111993200 
    ​Details  DOI  PMID  PMC  WoS 
  • 2001 | Journal Article
    ​ ​1.3 Å Structure of Arylsulfatase from Pseudomonas aeruginosa Establishes the Catalytic Mechanism of Sulfate Ester Cleavage in the Sulfatase Family​
    Boltes, I.; Czapinska, H.; Kahnert, A.; Bülow, R. von; Dierks, T.; Schmidt, B.   & Figura, K. von  et al.​ (2001) 
    Structure, 9(6) pp. 483​-491​.​ DOI: https://doi.org/10.1016/S0969-2126(01)00609-8 
    ​Details  DOI  PMID  PMC  WoS 
  • 2001 | Journal Article
    ​ ​Crystal structure of an enzyme-substrate complex provides insight into the interaction between human arylsulfatase A and its substrates during catalysis​
    Bülow, R. von; Schmidt, B. ; Dierks, T.; Figura, K. von   & Usón, I.​ (2001) 
    Journal of Molecular Biology, 305(2) pp. 269​-277​.​ DOI: https://doi.org/10.1006/jmbi.2000.4297 
    ​Details  DOI  PMID  PMC  WoS 
  • 1999 | Journal Article | 
    ​ ​Sequence determinants directing conversion of cysteine to formylglycine in eukaryotic sulfatases​
    Dierks, T.; Lecca, M.; Schlotterhose, P. ; Schmidt, B.   & Figura, K. von ​ (1999) 
    The EMBO Journal, 18(8) pp. 2084​-2091​.​
    ​Details 

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https://publications.goettingen-research-online.de URI: /cris/rp/rp08188
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