Prof. Dr. Dr. h. c. Kurt von Figura

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  • 2009 | Review
    ​ ​Molecular basis of multiple sulfatase deficiency, mucolipidosis II/III and Niemann-Pick C1 disease - Lysosomal storage disorders caused by defects of non-lysosomal proteins​
    Dierks, T.; Schlotawa, L.; Frese, M.-A.; Radhakrishnan, K.; von Figura, K.  & Schmidt, B.​ (2009)
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1793​(4) pp. 710​-725​.​
    Elsevier Science Bv. DOI: https://doi.org/10.1016/j.bbamcr.2008.11.015 
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Journal Article | Research Paper
    ​ ​Crystal structure of human pFGE, the paralog of the C alpha-formylglycine-generating enzyme​
    Dickmanns, A. ; Schmidt, B. ; Rudolph, M.; Mariappan, M.; Dierks, T.; Von Figura, K.   & Ficner, R. ​ (2005) 
    Journal of biological chemistry, 280(15) pp. 15180​-15187​.​ DOI: https://doi.org/10.1074/jbc.M414317200 
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Journal Article | Research Paper | 
    ​ ​Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme​
    Dierks, T.; Dickmanns, A. ; Preusser-Kunze, A.; Schmidt, B. ; Mariappan, M.; Von Figura, K.   & Ficner, R.  et al.​ (2005) 
    Cell, 121(4) pp. 541​-552​.​ DOI: https://doi.org/10.1016/j.cell.2005.03.001 
    ​Details  DOI  PMID  PMC  WoS 
  • 2003 | Journal Article | Research Paper
    ​ ​LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice​
    Gamp, A. C.; Tanaka, Y.; Lullmann-Rauch, R.; Wittke, D.; D'Hooge, R.; De Deyn, P. P. & Moser, T.  et al.​ (2003) 
    Human Molecular Genetics, 12(6) pp. 631​-646​.​ DOI: https://doi.org/10.1093/hmg/ddg062 
    ​Details  DOI  PMID  PMC  WoS 
  • 2003 | Journal Article
    ​ ​Locating the anomalous scatterer substructures in halide and sulfur phasing​
    Usón, I.; Schmidt, B.; Bülow, R. von; Grimme, S.; Figura, K. von ; Dauter, M. & Rajashankar, K. R. et al.​ (2003) 
    Acta Crystallographica Section D Structural Biology, 59 pp. 57​-66​.​ DOI: https://doi.org/10.1107/S090744490201884X 
    ​Details  DOI  PMID  PMC  WoS 
  • 2002 | Journal Article
    ​ ​Defective oligomerization of arylsulfatase A as a cause of its instability in lysosomes and metachromatic leukodystrophy​
    Bülow, R. von; Schmidt, B. ; Dierks, T.; Schwabauer, N.; Schilling, K.; Weber, E. & Usón, I. et al.​ (2002) 
    Journal of Biological Chemistry, 277(11) pp. 9455​-9461​.​ DOI: https://doi.org/10.1074/jbc.M111993200 
    ​Details  DOI  PMID  PMC  WoS 
  • 2001 | Journal Article
    ​ ​1.3 Å Structure of Arylsulfatase from Pseudomonas aeruginosa Establishes the Catalytic Mechanism of Sulfate Ester Cleavage in the Sulfatase Family​
    Boltes, I.; Czapinska, H.; Kahnert, A.; Bülow, R. von; Dierks, T.; Schmidt, B.   & Figura, K. von  et al.​ (2001) 
    Structure, 9(6) pp. 483​-491​.​ DOI: https://doi.org/10.1016/S0969-2126(01)00609-8 
    ​Details  DOI  PMID  PMC  WoS 
  • 2001 | Journal Article
    ​ ​Crystal structure of an enzyme-substrate complex provides insight into the interaction between human arylsulfatase A and its substrates during catalysis​
    Bülow, R. von; Schmidt, B. ; Dierks, T.; Figura, K. von   & Usón, I.​ (2001) 
    Journal of Molecular Biology, 305(2) pp. 269​-277​.​ DOI: https://doi.org/10.1006/jmbi.2000.4297 
    ​Details  DOI  PMID  PMC  WoS 
  • 2000 | Journal Article | 
    ​ ​Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice​
    Tanaka, Y.; Guhde, G.; Suter, A.; Eskelinen, E.-L.; Hartmann, D.; Lüllmann-Rauch, R. & Blanz, J. et al.​ (2000) 
    Nature, 406 pp. 902​-906​.​
    ​Details 
  • 1999 | Journal Article | 
    ​ ​Sequence determinants directing conversion of cysteine to formylglycine in eukaryotic sulfatases​
    Dierks, T.; Lecca, M.; Schlotterhose, P. ; Schmidt, B.   & Figura, K. von ​ (1999) 
    The EMBO Journal, 18(8) pp. 2084​-2091​.​
    ​Details 

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