Prof. Dr. med. Brit Mollenhauer

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  • 2022 | Journal Article
    ​ ​CSF-derived extracellular vesicles from patients with Parkinson's disease induce symptoms and pathology​
    Herman, S.; Djaldetti, R.; Mollenhauer, B.   & Offen, D.​ (2022) 
    Brain, art. awac261​.​ DOI: https://doi.org/10.1093/brain/awac261 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Toward preventing Parkinson’s disease​
    Mollenhauer, B.   & Arnim, C. A. F. von ​ (2022) 
    Science, 377(6608) pp. 818​-819​.​ DOI: https://doi.org/10.1126/science.add7162 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Studying the Parkinson’s disease metabolome and exposome in biological samples through different analytical and cheminformatics approaches: a pilot study​
    Talavera Andújar, B.; Aurich, D.; Aho, V. T. E.; Singh, R. R.; Cheng, T.; Zaslavsky, L. & Bolton, E. E. et al.​ (2022) 
    Analytical and Bioanalytical Chemistry,.​ DOI: https://doi.org/10.1007/s00216-022-04207-z 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Evaluation of the PREDIGT score’s performance in identifying newly diagnosed Parkinson’s patients without motor examination​
    Li, J.; Mestre, T. A.; Mollenhauer, B. ; Frasier, M.; Tomlinson, J. J.; Trenkwalder, C.   & Ramsay, T. et al.​ (2022) 
    npj Parkinson's Disease, 8(1).​ DOI: https://doi.org/10.1038/s41531-022-00360-5 
    ​Details  DOI 
  • 2022 | Journal Article | 
    ​ ​Reliability and validity of the Roche PD Mobile Application for remote monitoring of early Parkinson’s disease​
    Lipsmeier, F.; Taylor, K. I.; Postuma, R. B.; Volkova-Volkmar, E.; Kilchenmann, T.; Mollenhauer, B.   & Bamdadian, A. et al.​ (2022) 
    Scientific Reports, 12(1).​ DOI: https://doi.org/10.1038/s41598-022-15874-4 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Evidence for immune system alterations in peripheral biological fluids in Parkinson's disease​
    Bartl, M.; Xylaki, M.; Bähr, M. ; Weber, S.; Trenkwalder, C.   & Mollenhauer, B. ​ (2022) 
    Neurobiology of Disease, 170 art. S096999612200136X​.​ DOI: https://doi.org/10.1016/j.nbd.2022.105744 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​A data-driven system to identify REM sleep behavior disorder and to predict its progression from the prodromal stage in Parkinson's disease​
    Cesari, M.; Christensen, J. A.; Muntean, M.-L.; Mollenhauer, B. ; Sixel-Döring, F.; Sorensen, H. B. & Trenkwalder, C.  et al.​ (2021) 
    Sleep Medicine, 77 pp. 238​-248​.​ DOI: https://doi.org/10.1016/j.sleep.2020.04.010 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Preanalytical Stability of CSF Total and Oligomeric Alpha-Synuclein​
    Abdi, I. Y.; Majbour, N. K.; Willemse, E. A. J.; van de Berg, W. D. J.; Mollenhauer, B. ; Teunissen, C. E. & El-Agnaf, O. M.​ (2021) 
    Frontiers in Aging Neuroscience, 13.​ DOI: https://doi.org/10.3389/fnagi.2021.638718 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Arousal characteristics in patients with Parkinson’s disease and isolated rapid eye movement sleep behavior disorder​
    Brink-Kjær, A.; Cesari, M.; Sixel-Döring, F.; Mollenhauer, B. ; Trenkwalder, C. ; Mignot, E. & Sorensen, H. B D et al.​ (2021) 
    Sleep,.​ DOI: https://doi.org/10.1093/sleep/zsab167 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Clinically relevant copy-number variants in exome sequencing data of patients with dystonia​
    Zech, M.; Boesch, S.; Škorvánek, M.; Necpál, J.; Švantnerová, J.; Wagner, M. & Dincer, Y. et al.​ (2021) 
    Parkinsonism & Related Disorders, 84 pp. 129​-134​.​ DOI: https://doi.org/10.1016/j.parkreldis.2021.02.013 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​The Mutation Matters: CSF Profiles of GCase , Sphingolipids, α‐Synuclein in PD GBA​
    Lerche, S.; Schulte, C.; Wurster, I.; Machetanz, G.; Roeben, B.; Zimmermann, M. & Deuschle, C. et al.​ (2021) 
    Movement Disorders,.​ DOI: https://doi.org/10.1002/mds.28472 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Systematic characterization of human gut microbiome-secreted molecules by integrated multi-omics​
    De Saedeleer, B.; Malabirade, A.; Ramiro-Garcia, J.; Habier, J.; Trezzi, J.-P.; Peters, S. L. & Daujeumont, A. et al.​ (2021) 
    ISME Communications, 1(1) art. 82​.​ DOI: https://doi.org/10.1038/s43705-021-00078-0 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Peripheral decarboxylase inhibitors paradoxically induce aromatic L-amino acid decarboxylase​
    van Rumund, A.; Pavelka, L.; Esselink, R. A. J.; Geurtz, B. P. M.; Wevers, R. A.; Mollenhauer, B.   & Krüger, R. et al.​ (2021) 
    npj Parkinson's Disease, 7(1).​ DOI: https://doi.org/10.1038/s41531-021-00172-z 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Private variants in PRKN are associated with late-onset Parkinson's disease​
    Hopfner, F.; Mueller, S. H.; Szymczak, S.; Junge, O.; Tittmann, L.; May, S. & Lohmann, K. et al.​ (2020) 
    Parkinsonism & Related Disorders, 75 pp. 24​-26​.​ DOI: https://doi.org/10.1016/j.parkreldis.2020.05.003 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Clinical and Dopamine Transporter Imaging Characteristics of Leucine Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross‐Sectional Study​
    Simuni, T.; Brumm, M. C.; Uribe, L.; Caspell‐Garcia, C.; Coffey, C. S.; Siderowf, A. & Alcalay, R. N. et al.​ (2020) 
    Movement Disorders, 35(5) pp. 833​-844​.​ DOI: https://doi.org/10.1002/mds.27989 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates​
    Bourdenx, M.; Nioche, A.; Dovero, S.; Arotcarena, M.-L.; Camus, S.; Porras, G. & Thiolat, M.-L. et al.​ (2020) 
    Science Advances, 6(20) pp. eaaz9165​.​ DOI: https://doi.org/10.1126/sciadv.aaz9165 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Rare Variants in Specific Lysosomal Genes Are Associated With Parkinson's Disease​
    Hopfner, F.; Mueller, S. H.; Szymczak, S.; Junge, O.; Tittmann, L.; May, S. & Lohmann, K. et al.​ (2020) 
    Movement Disorders, 35(7) pp. 1245​-1248​.​ DOI: https://doi.org/10.1002/mds.28037 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Fine‐Mapping of SNCA in Rapid Eye Movement Sleep Behavior Disorder and Overt Synucleinopathies​
    Krohn, L.; Wu, R. Y. J.; Heilbron, K.; Ruskey, J. A.; Laurent, S. B.; Blauwendraat, C. & Alam, A. et al.​ (2020) 
    Annals of Neurology, 87(4) pp. 584​-598​.​ DOI: https://doi.org/10.1002/ana.25687 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Potential sources of interference with the highly sensitive detection and quantification of alpha‐synuclein seeds by qRT‐QuIC​
    Ruf, V. C.; Shi, S.; Schmidt, F.; Weckbecker, D.; Nübling, G. S.; Ködel, U. & Mollenhauer, B.  et al.​ (2020) 
    FEBS Open Bio, 10(5) pp. 883​-893​.​ DOI: https://doi.org/10.1002/2211-5463.12844 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​SMPD1 variants do not have a major role in rapid eye movement sleep behavior disorder​
    Rudakou, U.; Futhey, N. C.; Krohn, L.; Ruskey, J. A.; Heilbron, K.; Cannon, P. & Alam, A. et al.​ (2020) 
    Neurobiology of Aging, 93 pp. 142.e5​-142.e7​.​ DOI: https://doi.org/10.1016/j.neurobiolaging.2020.04.005 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Comprehensive Analysis of Familial Parkinsonism Genes in Rapid‐Eye‐Movement Sleep Behavior Disorder​
    Mufti, K.; Rudakou, U.; Yu, E.; Krohn, L.; Ruskey, J. A.; Asayesh, F. & Laurent, S. B. et al.​ (2020) 
    Movement Disorders, 36(1) pp. 235​-240​.​ DOI: https://doi.org/10.1002/mds.28318 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates​
    Arotcarena, M.-L.; Dovero, S.; Prigent, A.; Bourdenx, M.; Camus, S.; Porras, G. & Thiolat, M.-L. et al.​ (2020) 
    Brain: A Journal of Neurology, 143(5) pp. 1462​-1475​.​ DOI: https://doi.org/10.1093/brain/awaa096 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​GBA variants in REM sleep behavior disorder​
    Krohn, L.; Ruskey, J. A.; Rudakou, U.; Leveille, E.; Asayesh, F.; Hu, M. T. & Arnulf, I. et al.​ (2020) 
    Neurology, 95(8) pp. e1008​-e1016​.​ DOI: https://doi.org/10.1212/WNL.0000000000010042 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​β-Amyloid and tau biomarkers and clinical phenotype in dementia with Lewy bodies​
    Ferreira, D.; Przybelski, S. A.; Lesnick, T. G.; Lemstra, A. W.; Londos, E.; Blanc, F. & Nedelska, Z. et al.​ (2020) 
    Neurology, 95(24) pp. e3257​-e3268​.​ DOI: https://doi.org/10.1212/WNL.0000000000010943 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​In vivo distribution of α-synuclein in multiple tissues and biofluids in Parkinson disease​
    Chahine, L. M.; Beach, T. G.; Brumm, M. C.; Adler, C. H.; Coffey, C. S.; Mosovsky, S. & Caspell-Garcia, C. et al.​ (2020) 
    Neurology, 95(9) pp. e1267​-e1284​.​ DOI: https://doi.org/10.1212/WNL.0000000000010404 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Dopamine transporter imaging predicts clinically‐defined α ‐synucleinopathy in REM sleep behavior disorder​
    Chahine, L. M.; Brumm, M. C.; Caspell‐Garcia, C.; Oertel, W.; Mollenhauer, B. ; Amara, A. & Fernandez‐Arcos, A. et al.​ (2020) 
    Annals of Clinical and Translational Neurology, 8(1) pp. 201​-212​.​ DOI: https://doi.org/10.1002/acn3.51269 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Elemental fingerprint: Reassessment of a cerebrospinal fluid biomarker for Parkinson's disease​
    Maass, F. ; Michalke, B.; Willkommen, D.; Leha, A. ; Schulte, C.; Tönges, L.   & Mollenhauer, B.  et al.​ (2020) 
    Neurobiology of Disease, 134 pp. 104677​.​ DOI: https://doi.org/10.1016/j.nbd.2019.104677 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Neurogeriatrie – eine Vision für die verbesserte Versorgung und Forschung für geriatrische Patienten mit führend neurologischen Erkrankungen​
    Jacobs, A. H.; Emmert, K.; Baron, R.; Bartsch, T.; Bauer, J.; Becker, C. & Berg, D.  et al.​ (2020) 
    Zeitschrift für Gerontologie und Geriatrie, 53(4) pp. 340​-346​.​ DOI: https://doi.org/10.1007/s00391-020-01734-1 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Blood Contamination in CSF and Its Impact on Quantitative Analysis of Alpha-Synuclein​
    Barkovits, K.; Kruse, N. ; Linden, A.; Tönges, L.; Pfeiffer, K. ; Mollenhauer, B.   & Marcus, K.​ (2020) 
    Cells, 9(2) pp. 370​.​ DOI: https://doi.org/10.3390/cells9020370 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson's Disease Progression​
    Mollenhauer, B. ; Dakna, M.; Kruse, N. ; Galasko, D.; Foroud, T.; Zetterberg, H. & Schade, S.  et al.​ (2020) 
    Movement Disorders, 35(11) pp. 1999​-2008​.​ DOI: https://doi.org/10.1002/mds.28206 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson’s disease: a study in LRRK2 mutation carriers​
    Majbour, N. K.; Aasly, J. O.; Hustad, E.; Thomas, M. A.; Vaikath, N. N.; Elkum, N. & van de Berg, W. D. J. et al.​ (2020) 
    Translational Neurodegeneration, 9(1).​ DOI: https://doi.org/10.1186/s40035-020-00192-4 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Levodopa Equivalent Dose Conversion Factors: An Updated Proposal Including Opicapone and Safinamide​
    Schade, S. ; Mollenhauer, B.   & Trenkwalder, C. ​ (2020) 
    Movement Disorders Clinical Practice, 7(3) pp. 343​-345​.​ DOI: https://doi.org/10.1002/mdc3.12921 
    ​Details  DOI 
  • 2020 | Journal Article | Research Paper | 
    ​ ​A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cytosol​
    Gerdes, C.; Waal, N.; Offner, T.; Fornasiero, E. F. ; Wender, N.; Verbarg, H. & Manzini, I. et al.​ (2020) 
    Nature Communications, 11(1).​ DOI: https://doi.org/10.1038/s41467-020-16575-0 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article | Research Paper | 
    ​ ​Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity​
    Cantuti-Castelvetri, L.; Ojha, R.; Pedro, L. D.; Djannatian, M.; Franz, J.; Kuivanen, S. & van der Meer, F.  et al.​ (2020) 
    Science, 370(6518) pp. 856​-860​.​ DOI: https://doi.org/10.1126/science.abd2985 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article
    ​ ​Parkinson’s disease biomarkers based on α‐synuclein​
    Fayyad, M.; Salim, S.; Majbour, N.; Erskine, D.; Stoops, E.; Mollenhauer, B.   & El‐Agnaf, O. M. A.​ (2019) 
    Journal of Neurochemistry, 150(5) pp. 626​-636​.​ DOI: https://doi.org/10.1111/jnc.14809 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Feasibility and safety of lumbar puncture in the Parkinson's disease research participants: Parkinson's Progression Marker Initiative (PPMI)​
    Prakash, N.; Caspell-Garcia, C.; Coffey, C.; Siderowf, A.; Tanner, C. M.; Kieburtz, K. & Mollenhauer, B.  et al.​ (2019) 
    Parkinsonism & Related Disorders, 62 pp. 201​-209​.​ DOI: https://doi.org/10.1016/j.parkreldis.2018.12.025 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Safety and efficacy of epigallocatechin gallate in multiple system atrophy (PROMESA): a randomised, double-blind, placebo-controlled trial​
    Levin, J.; Maaß, S.; Schuberth, M.; Giese, A.; Oertel, W. H; Poewe, W. & Trenkwalder, C.  et al.​ (2019) 
    The Lancet Neurology, 18(8) pp. 724​-735​.​ DOI: https://doi.org/10.1016/S1474-4422(19)30141-3 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Risk of Parkinson's disease dementia related to level I MDS PD‐MCI​
    Hoogland, J.; Boel, J. A.; Bie, R. M.; Schmand, B. A.; Geskus, R. B.; Dalrymple‐Alford, J. C. & Marras, C. et al.​ (2019) 
    Movement Disorders, 34(3) pp. 430​-435​.​ DOI: https://doi.org/10.1002/mds.27617 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Cognitive decline in Parkinson’s disease: the impact of the motor phenotype on cognition​
    Wojtala, J.; Heber, I. A.; Neuser, P.; Heller, J.; Kalbe, E.; Rehberg, S. P & Storch, A. et al.​ (2019) 
    Journal of Neurology, Neurosurgery & Psychiatry, 90(2) pp. 171​-179​.​ DOI: https://doi.org/10.1136/jnnp-2018-319008 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​SEAweb: the small RNA Expression Atlas web application​
    Rahman, R.-U. ; Liebhoff, A.-M.; Bansal, V.; Fiosins, M.; Rajput, A. ; Sattar, A. & Magruder, D. S et al.​ (2019) 
    Nucleic Acids Research, 48(D1) pp. D204​-D219​.​ DOI: https://doi.org/10.1093/nar/gkz869 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson’s Disease​
    Hertel, J.; Harms, A. C.; Heinken, A.; Baldini, F.; Thinnes, C. C.; Glaab, E. & Vasco, D. A. et al.​ (2019) 
    Cell Reports, 29(7) pp. 1767​-1777.e8​.​ DOI: https://doi.org/10.1016/j.celrep.2019.10.035 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Predicting Progression in Parkinson’s Disease Using Baseline and 1-Year Change Measures​
    Chahine, L. M.; Siderowf, A.; Barnes, J.; Seedorff, N.; Caspell-Garcia, C.; Simuni, T. & Coffey, C. S. et al.​ (2019) 
    Journal of Parkinson's Disease, 9(4) pp. 665​-679​.​ DOI: https://doi.org/10.3233/JPD-181518 
    ​Details  DOI 
  • 2019 | Journal Article | Research Paper | 
    ​ ​A combined miRNA–piRNA signature to detect Alzheimer’s disease​
    Jain, G.; Stuendl, A.; Rao, P.; Berulava, T.; Pena Centeno, T.; Kaurani, L.   & Burkhardt, S.  et al.​ (2019) 
    Translational Psychiatry, 9(1).​ DOI: https://doi.org/10.1038/s41398-019-0579-2 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article
    ​ ​White matter hyperintensities are not associated with cognitive decline in early Parkinson's disease - The DeNoPa cohort​
    Hanning, U.; Teuber, A.; Lang, E.; Trenkwalder, C. ; Mollenhauer, B.   & Minnerup, H.​ (2019) 
    Parkinsonism & Related Disorders, 69 pp. 61​-67​.​ DOI: https://doi.org/10.1016/j.parkreldis.2019.10.016 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Feasibility and Safety of Multicenter Tissue and Biofluid Sampling for α-Synuclein in Parkinson’s Disease: The Systemic Synuclein Sampling Study (S4)​
    Chahine, L. M.; Beach, T. G.; Seedorff, N.; Caspell-Garcia, C.; Coffey, C. S.; Brumm, M. & Adler, C. H. et al.​ (2018) 
    Journal of Parkinson's Disease, 8(4) pp. 517​-527​.​ DOI: https://doi.org/10.3233/JPD-181434 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry​
    Lewczuk, P. ; Riederer, P.; O’Bryant, S. E.; Verbeek, M. M.; Dubois, B.; Visser, P. J. & Jellinger, K. A. et al.​ (2018) 
    The World Journal of Biological Psychiatry, 19(4) pp. 244​-328​.​ DOI: https://doi.org/10.1080/15622975.2017.1375556 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Immunohistochemical Method and Histopathology Judging for the Systemic Synuclein Sampling Study (S4)​
    Beach, T. G.; Serrano, G. E.; Kremer, T.; Canamero, M.; Dziadek, S.; Sade, H. & Derkinderen, P. et al.​ (2018) 
    Journal of Neuropathology and Experimental Neurology, 77(9) pp. 793​-802​.​ DOI: https://doi.org/10.1093/jnen/nly056 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Psychometric Properties of an Abbreviated Version of the Apathy Evaluation Scale for Parkinson Disease (AES-12PD)​
    Stankevich, Y.; Lueken, U.; Balzer-Geldsetzer, M.; Dodel, R.; Gräber-Sultan, S.; Berg, D. & Liepelt-Scarfone, I. et al.​ (2018) 
    American Journal of Geriatric Psychiatry, 26(10) pp. 1079​-1090​.​ DOI: https://doi.org/10.1016/j.jagp.2018.06.012 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Protein variability in cerebrospinal fluid and its possible implications for neurological protein biomarker research​
    Schilde, L. M.; Kösters, S.; Steinbach, S.; Schork, K.; Eisenacher, M.; Galozzi, S. & Turewicz, M. et al.​ (2018) 
    PLoS One, 13(11) pp. e0206478​.​ DOI: https://doi.org/10.1371/journal.pone.0206478 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Baseline predictors for progression 4 years after Parkinson's disease diagnosis in the De Novo Parkinson Cohort (DeNoPa)​
    Mollenhauer, B. ; Zimmermann, J.; Sixel‐Döring, F.; Focke, N. K. ; Wicke, T.; Ebentheuer, J. & Schaumburg, M. et al.​ (2018) 
    Movement Disorders, 34(1) pp. 67​-77​.​ DOI: https://doi.org/10.1002/mds.27492 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Detecting Mild Cognitive Deficits in Parkinson's Disease: Comparison of Neuropsychological Tests​
    Hoogland, J.; van Wanrooij, L. L.; Boel, J. A.; Goldman, J. G.; Stebbins, G. T.; Dalrymple-Alford, J. C. & Marras, C. et al.​ (2018) 
    Movement Disorders, 33(11) pp. 1750​-1759​.​ DOI: https://doi.org/10.1002/mds.110 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Diagnostic exome sequencing in early-onset Parkinson's disease confirms VPS13C as a rare cause of autosomal-recessive Parkinson's disease​
    Schormair, B.; Kemlink, D.; Mollenhauer, B. ; Fiala, O.; Machetanz, G.; Roth, J. & Berutti, R. et al.​ (2018) 
    Clinical Genetics, 93(3) pp. 603​-612​.​ DOI: https://doi.org/10.1111/cge.13124 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​LRRK2 protective haplotype and full sequencing study in REM sleep behavior disorder​
    Ouled Amar Bencheikh, B.; Ruskey, J. A.; Arnulf, I.; Dauvilliers, Y.; Monaca, C. C.; De Cock, V. C. & Gagnon, J.-F. et al.​ (2018) 
    Parkinsonism & Related Disorders, 52 pp. 98​-101​.​ DOI: https://doi.org/10.1016/j.parkreldis.2018.03.019 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Validation of α-Synuclein as a CSF Biomarker for Sporadic Creutzfeldt-Jakob Disease​
    Llorens, F. ; Kruse, N. ; Karch, A. ; Schmitz, M.; Zafar, S. ; Gotzmann, N.   & Sun, T. et al.​ (2018) 
    Molecular Neurobiology, 55(3) pp. 2249​-2257​.​ DOI: https://doi.org/10.1007/s12035-017-0479-5 
    ​Details  DOI 
  • 2017 | Journal Article | 
    ​ ​Longitudinal CSF biomarkers in patients with early Parkinson disease and healthy controls​
    Mollenhauer, B. ; Caspell-Garcia, C. J; Coffey, C.; Taylor, P.; Shaw, L. M.; Trojanowski, J. Q. & Singleton, A. et al.​ (2017) 
    Neurology, 89(19) pp. 1959​-1969​.​ DOI: https://doi.org/10.1212/WNL.0000000000004609 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​A user's guide for α-synuclein biomarker studies in biological fluids: ​Perianalytical considerations​
    Mollenhauer, B. ; Batrla, R.; El-Agnaf, O.; Galasko, D. R; Lashuel, H.; Merchant, K. & Shaw, L. M et al.​ (2017) 
    Movement Disorders, 32(8) pp. 1117​-1130​.​ DOI: https://doi.org/10.1002/mds.27090 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Diagnosis and management of dementia with Lewy bodies: ​Fourth consensus report of the DLB Consortium​
    McKeith, I.; Boeve, B.; Dickson, D. W.; Halliday, G.; Taylor, J.-P.; Weintraub, D. & Aarsland, D. et al.​ (2017) 
    Neurology, 89(1) pp. 88​-100​.​ DOI: https://doi.org/10.1212/WNL.0000000000004058 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Which ante mortem clinical features predict progressive supranuclear palsy pathology?​
    Respondek, G.; Kurz, C.; Arzberger, T.; Compta, Y.; Englund, E.; Ferguson, L. & Gelpi, E. et al.​ (2017) 
    Movement Disorders, 32(7) pp. 995​-1005​.​ DOI: https://doi.org/10.1002/mds.27034 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria​
    Höglinger, G.; Respondek, G.; Stamelou, M.; Kurz, C.; Josephs, K.; Lang, A. & Mollenhauer, B.  et al.​ (2017) 
    Movement Disorders, 32(6) pp. 853​-864​.​ DOI: https://doi.org/10.1002/mds.26987 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Evaluation of α-synuclein as a novel cerebrospinal fluid biomarker in different forms of prion diseases​
    Llorens, F. ; Kruse, N. ; Schmitz, M. ; Gotzmann, N. ; Golanska, E.; Thüne, K.   & Zejneli, O. et al.​ (2017) 
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 13(6) pp. 710​-719​.​ DOI: https://doi.org/10.1016/j.jalz.2016.09.013 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Development of a Biochemical Diagnosis of Parkinson Disease by Detection of α-Synuclein Misfolded Aggregates in Cerebrospinal Fluid​
    Shahnawaz, M. R.; Tokuda, T.; waragai, M.; Mendez, N.; ishii, r.; Trenkwalder, C.   & Mollenhauer, B.  et al.​ (2017) 
    JAMA Neurology, 74(2) pp. 163​-172​.​ DOI: https://doi.org/10.1001/jamaneurol.2016.4547 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Metabolic profiling of body fluids and multivariate data analysis​
    Trezzi, J.-P.; Jäger, C.; Galozzi, S.; Barkovits, K.; Marcus, K.; Mollenhauer, B.   & Hiller, K.​ (2017) 
    MethodsX, 4 pp. 95​-103​.​ DOI: https://doi.org/10.1016/j.mex.2017.02.004 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Distinct metabolomic signature in cerebrospinal fluid in early parkinson's disease​
    Trezzi, J.-P.; Galozzi, S.; Jaeger, C.; Barkovits, K.; Brockmann, K.; Maetzler, W. & Berg, D. et al.​ (2017) 
    Movement Disorders, 32(10) pp. 1401​-1408​.​ DOI: https://doi.org/10.1002/mds.27132 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Acute Levodopa Challenge Test in Patients with de novo Parkinson's Disease: Data from the DeNoPa Cohort​
    Schade, S. ; Sixel-Döring, F.; Ebentheuer, J.; Schulz, X. ; Trenkwalder, C.   & Mollenhauer, B. ​ (2017) 
    Movement Disorders Clinical Practice, 4(5) pp. 755​-762​.​ DOI: https://doi.org/10.1002/mdc3.12511 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Baseline prevalence and longitudinal evolution of non-motor symptoms in early Parkinson’s disease: the PPMI cohort​
    Simuni, T.; Caspell-Garcia, C.; Coffey, C. S; Weintraub, D.; Mollenhauer, B. ; Lasch, S. & Tanner, C. M et al.​ (2017) 
    Journal of Neurology, Neurosurgery & Psychiatry, 89(1) pp. 78​-88​.​ DOI: https://doi.org/10.1136/jnnp-2017-316213 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​The nasal and gut microbiome in Parkinson's disease and idiopathic rapid eye movement sleep behavior disorder​
    Heintz-Buschart, A.; Pandey, U.; Wicke, T.; Sixel-Döring, F.; Janzen, A.; Sittig-Wiegand, E. & Trenkwalder, C.  et al.​ (2017) 
    Movement Disorders, 33(1) pp. 88​-98​.​ DOI: https://doi.org/10.1002/mds.27105 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Cerebrospinal Fluid Biomarkers of Cognitive Decline in Parkinson's Disease​
    Johar, I.; Mollenhauer, B.   & Aarsland, D.​ (2017) 
    International Review of Neurobiology, 132 pp. 275​-294​.​ DOI: https://doi.org/10.1016/bs.irn.2016.12.001 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Psychometric properties of the apathy evaluation scale in patients with Parkinson's disease​
    Lueken, U.; Evens, R.; Balzer-Geldsetzer, M.; Baudrexel, S.; Dodel, r.; Gräber-Sultan, S. & Hilker-Roggendorf, R. et al.​ (2017) 
    International journal of methods in psychiatric research, 26(4).​ DOI: https://doi.org/10.1002/mpr.1564 
    ​Details  DOI  PMID  PMC 
  • 2017 | Journal Article
    ​ ​Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinson's disease​
    Mak, E.; Su, L.; Williams, G.; Firbank, M.; Lawson, R. A.; Yarnall, A. & Duncan, G. et al.​ (2017) 
    Neurobiology of Aging, 55 pp. 78​-90​.​ DOI: https://doi.org/10.1016/j.neurobiolaging.2017.03.012 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article
    ​ ​Invasive Therapien bei fortgeschrittener Parkinson-Krankheit: Was wann für wen?​
    Sixel-Döring, F.; Ebentheuer, J.; Mollenhauer, B. ; Bürk, K.   & Trenkwalder, C. ​ (2016) 
    Aktuelle Neurologie, 43(09) pp. 559​-567​.​ DOI: https://doi.org/10.1055/s-0042-119446 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics​
    Lelental, N.; Brandner, S.; Kofanova, O.; Blennow, K.; Zetterberg, H.; Andreasson, U. & Engelborghs, S. et al.​ (2016) 
    Journal of Alzheimer's Disease, 52(1) pp. 51​-64​.​ DOI: https://doi.org/10.3233/jad-150883 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Molecular Alterations in the Cerebellum of Sporadic Creutzfeldt–Jakob Disease Subtypes with DJ-1 as a Key Regulator of Oxidative Stress​
    Tahir, W. ; Zafar, S. ; Llorens, F. ; Arora, A. S. ; Thüne, K. ; Schmitz, M.   & Gotzmann, N.  et al.​ (2016) 
    Molecular Neurobiology, 55(1) pp. 517​-537​.​ DOI: https://doi.org/10.1007/s12035-016-0294-4 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​The utility of α-synuclein as biofluid marker in neurodegenerative diseases: a systematic review of the literature​
    Simonsen, A. H.; Kuiperij, B.; El-Agnaf, O. M. A.; Engelborghs, S.; Herukka, S.-K.; Parnetti, L. & Rektorova, I. et al.​ (2016) 
    Biomarkers in Medicine, 10(1) pp. 19​-34​.​ DOI: https://doi.org/10.2217/BMM.14.105 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Monitoring of 30 marker candidates in early Parkinson disease as progression markers​
    Mollenhauer, B. ; Zimmermann, J.; Sixel-Döring, F.; Focke, N. K. ; Wicke, T.; Ebentheuer, J. & Schaumburg, M. et al.​ (2016) 
    Neurology, 87(2) pp. 168​-177​.​ DOI: https://doi.org/10.1212/WNL.0000000000002651 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article
    ​ ​Verbal memory declines more in female patients with Parkinson's disease: the importance of gender-corrected normative data​
    Fengler, S.; Roeske, S.; Heber, I.; Reetz, K.; Schulz, J. B. ; Riedel, O. & Wittchen, H. et al.​ (2016) 
    Psychological Medicine, 46(11) pp. 2275​-2286​.​ DOI: https://doi.org/10.1017/S0033291716000908 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Review
    ​ ​Fluid biomarkers in multiple system atrophy: A review of the MSA Biomarker Initiative​
    Laurens, B.; Constantinescu, R.; Freeman, R.; Gerhard, A.; Jellinger, K.; Jeromin, A.& Krismer, F. et al.​ (2015)
    Neurobiology of Disease, 80​ pp. 29​-41​.​
    Academic Press Inc Elsevier Science. DOI: https://doi.org/10.1016/j.nbd.2015.05.004 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper | 
    ​ ​Extracellular vesicle sorting of alpha-Synuclein is regulated by sumoylation​
    Kunadt, M.; Eckermann, K.; Stuendl, A.; Gong, J.; Russo, B.; Strauss, K. & Rai, S. et al.​ (2015) 
    Acta Neuropathologica, 129(5) pp. 695​-713​.​ DOI: https://doi.org/10.1007/s00401-015-1408-1 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper | 
    ​ ​Systematic Comparison of the Effects of Alpha-synuclein Mutations on Its Oligomerization and Aggregation​
    Lazaro, D. F. ; Rodrigues, E. F. ; Langohr, R.; Shahpasandzadeh, H.; Ribeiro, T.; Guerreiro, P.   & Gerhardt, E.  et al.​ (2014) 
    PLoS Genetics, 10 art. e1004741​.​ DOI: https://doi.org/10.1371/journal.pgen.1004741 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​Tau protein and 14-3-3 protein in the differential diagnosis of Creutzfeldt-Jakob disease​
    Otto, M. ; Wiltfang, J. ; Cepek, L. ; Neumann, M.; Mollenhauer, B. ; Steinacker, P.   & Ciesielczyk, B.  et al.​ (2012) 
    Neurology, 58(2) pp. 192​-197​.​ DOI: https://doi.org/10.1212/wnl.58.2.192 
    ​Details  DOI 
  • 2012 | Journal Article
    ​ ​Biochemical premotor biomarkers for Parkinson's disease​
    Mollenhauer, B.   & Zhang, J.​ (2012) 
    Movement Disorders, 27(5) pp. 644​-650​.​ DOI: https://doi.org/10.1002/mds.24956 
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Journal Article
    ​ ​Tau protein, A beta 42 and S-100B protein in cerebrospinal fluid of patients with dementia with Lewy bodies​
    Mollenhauer, B. ; Cepek, L.; Bibl, M. ; Wiltfang, J.; Schulz-Schaeffer, W. J. ; Ciesielczyk, B.   & Neumann, M. et al.​ (2005) 
    Dementia and Geriatric Cognitive Disorders, 19(2-3) pp. 164​-170​.​ DOI: https://doi.org/10.1159/000083178 
    ​Details  DOI  PMID  PMC  WoS 

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