Christoph Engel

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  • 2022 | Journal Article | Research Paper | 
    ​ ​Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry​
    Dumont, M.; Weber-Lassalle, N.; Joly-Beauparlant, C.; Ernst, C.; Droit, A.; Feng, B.-J. & Dubois, S. et al.​ (2022) 
    Cancers, 14(14).​ DOI: https://doi.org/10.3390/cancers14143363 
    ​Details  DOI 
  • 2018 | Journal Article | 
    ​ ​Prevalence of pathogenic BRCA1/2 germline mutations among 802 women with unilateral triple-negative breast cancer without family cancer history​
    Engel, C. ; Rhiem, K.; Hahnen, E.; Loibl, S.; Weber, K. E.; Seiler, S. & Zachariae, S. et al.​ (2018) 
    BMC Cancer, 18(1) art. 265​.​ DOI: https://doi.org/10.1186/s12885-018-4029-y 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Structural Basis of RNA Polymerase I Transcription Initiation​
    Engel, C. ; Gubbey, T.; Neyer, S.; Sainsbury, S.; Oberthuer, C.; Baejen, C. & Bernecky, C. et al.​ (2017) 
    Cell, 169(1) pp. 120​-131​.​ DOI: https://doi.org/10.1016/j.cell.2017.03.003 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | 
    ​ ​Structure of RNA polymerase I transcribing ribosomal DNA genes​
    Neyer, S.; Kunz, M.; Geiss, C.; Hantsche, M. ; Hodirnau, V.-V.; Seybert, A. & Engel, C.  et al.​ (2016) 
    Nature, 540(7634) pp. 607​-610​.​ DOI: https://doi.org/10.1038/nature20561 
    ​Details  DOI  PMID  PMC 
  • 2016 | Journal Article | Research Paper
    ​ ​Mechanisms of backtrack recovery by RNA polymerases I and II​
    Lisica, A.; Engel, C. ; Jahnel, M.; Roldan, E.; Galburt, E. A.; Cramer, P.   & Grill, S. W.​ (2016) 
    Proceedings of the National Academy of Sciences, 113(11) pp. 2946​-2951​.​ DOI: https://doi.org/10.1073/pnas.1517011113 
    ​Details  DOI  PMID  PMC  WoS 
  • 2016 | Journal Article | Research Paper | 
    ​ ​RNA polymerase I-Rrn3 complex at 4.8 angstrom resolution​
    Engel, C. ; Plitzko, J. & Cramer, P. ​ (2016) 
    Nature Communications, 7 art. 12129​.​ DOI: https://doi.org/10.1038/ncomms12129 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper
    ​ ​An alternative RNA polymerase I structure reveals a dimer hinge​
    Kostrewa, D.; Kuhn, C.-D.; Engel, C.   & Cramer, P. ​ (2015) 
    Acta Crystallographica Section D Biological Crystallography, 71 pp. 1850​-1855​.​ DOI: https://doi.org/10.1107/S1399004715012651 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | Research Paper | 
    ​ ​RNA polymerase I structure and transcription regulation​
    Engel, C. ; Sainsbury, S.; Cheung, A. C.; Kostrewa, D. & Cramer, P. ​ (2013) 
    Nature, 502(7473) pp. 650​-655​.​ DOI: https://doi.org/10.1038/nature12712 
    ​Details  DOI  PMID  PMC  WoS 
  • 2007 | Journal Article
    ​ ​The additive effect of p53 Arg72Pro and RNASEL Arg462Gln genotypes on age of disease onset in Lynch syndrome patients with pathogenic germline mutations in MSH2 or MLH1​
    Krüger, S.; Engel, C. ; Bier, A.; Silber, A.-S.; Görgens, H.; Mangold, E. & Pagenstecher, C. et al.​ (2007) 
    Cancer Letters, 252(1) pp. 55​-64​.​ DOI: https://doi.org/10.1016/j.canlet.2006.12.006 
    ​Details  DOI  PMID  PMC  WoS 

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