Dr. rer. nat. Thomas Monecke

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  • 2020 | Journal Article
    ​ ​OpenPepXL: An Open-Source Tool for Sensitive Identification of Cross-Linked Peptides in XL-MS​
    Netz, E.; Dijkstra, T. M.; Sachsenberg, T.; Zimmermann, L.; Walzer, M.; Monecke, T.   & Ficner, R.  et al.​ (2020) 
    Molecular & Cellular Proteomics, 19(12) pp. 2157​-2168​.​ DOI: https://doi.org/10.1074/mcp.TIR120.002186 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Crystal structure of the 239 kDa nuclear export complex CRM1 - RanGTP - Snurportin1 - Nup214 - MBP​
    Ficner, R. ; Monecke, T. ; Port, S. A.; Weiß, M. S.; Kehlenbach, R. H.   & Dickmanns, A. ​ (2016) 
    Acta Crystallographica Section A Foundations and Advances, 72(a1) pp. s30​-s30​.​ DOI: https://doi.org/10.1107/S2053273316099526 
    ​Details  DOI 
  • 2015 | Journal Article | 
    ​ ​Structural Basis of Targeting the Exportin CRM1 in Cancer​
    Dickmanns, A. ; Monecke, T.   & Ficner, R. ​ (2015) 
    Cells, 4(3) pp. 538​-568​.​ DOI: https://doi.org/10.3390/cells4030538 
    ​Details  DOI 
  • 2015 | Journal Article | Research Paper | 
    ​ ​Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export​
    Port, S. A.; Monecke, T. ; Dickmanns, A. ; Spillner, C.; Hofele, R.; Urlaub, H.   & Ficner, R.  et al.​ (2015) 
    Cell Reports, 13(4) pp. 690​-702​.​ DOI: https://doi.org/10.1016/j.celrep.2015.09.042 
    ​Details  DOI  PMID  PMC  WoS 
  • 2015 | Journal Article | Research Paper
    ​ ​Combining dehydration, construct optimization and improved data collection to solve the crystal structure of a CRM1-RanGTP-SPN1-Nup214 quaternary nuclear export complex​
    Monecke, T. ; Dickmanns, A. ; Weiss, M. S.; Port, S. A.; Kehlenbach, R. H.   & Ficner, R. ​ (2015) 
    Acta Crystallographica Section F Structural Biology Communications, 71 pp. 1481​-1487​.​ DOI: https://doi.org/10.1107/S2053230X15021524 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Review | 
    ​ ​Allosteric control of the exportin CRM1 unraveled by crystal structure analysis​
    Monecke, T. ; Dickmanns, A.  & Ficner, R. ​ (2014)
    FEBS Journal, 281​(18) pp. 4179​-4194​.​
    Wiley-blackwell. DOI: https://doi.org/10.1111/febs.12842 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper | 
    ​ ​Crystal Structures of the Novel Cytosolic 5'-Nucleotidase IIIB Explain Its Preference for m7GMP​
    Monecke, T. ; Buschmann, J.; Neumann, P. ; Wahle, E. & Ficner, R. ​ (2014) 
    PLoS ONE, 9(3) art. e90915​.​ DOI: https://doi.org/10.1371/journal.pone.0090915 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article | Research Paper
    ​ ​Translation Initiation Factor eIF3b Contains a Nine-Bladed β-Propeller and Interacts with the 40S Ribosomal Subunit​
    Liu, Y.; Neumann, P. ; Kuhle, B.; Monecke, T. ; Schell, S.; Chari, A. & Ficner, R. ​ (2014) 
    Structure, 22(6) pp. 923​-930​.​ DOI: https://doi.org/10.1016/j.str.2014.03.010 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article
    ​ ​Structural Determinants of Conformational Flexibility and Long-Range Allostery of the CRM1 Export Complex​
    Monecke, T. ; Haselbach, D.; Voß, B.; Russek, A.; Neumann, P. ; Thomson, E. & Hurt, E. et al.​ (2013) 
    Biophysical Journal, 104(2, Supplement 1) pp. 68a​.​ DOI: https://doi.org/10.1016/j.bpj.2012.11.411 
    ​Details  DOI 
  • 2013 | Journal Article | Research Paper
    ​ ​Structural basis for cooperativity of CRM1 export complex formation​
    Monecke, T. ; Haselbach, D.; Voss, B.; Russek, A.; Neumann, P. ; Thomson, E. & Hurt, E. et al.​ (2013) 
    Proceedings of the National Academy of Sciences, 110(3) pp. 960​-965​.​ DOI: https://doi.org/10.1073/pnas.1215214110 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | Research Paper
    ​ ​Structural Determinants and Mechanism of Mammalian CRM1 Allostery​
    Doelker, N.; Blanchet, C. E.; Voss, B.; Haselbach, D.; Kappel, C.; Monecke, T.   & Svergun, D. I. et al.​ (2013) 
    Structure, 21(8) pp. 1350​-1360​.​ DOI: https://doi.org/10.1016/j.str.2013.05.015 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Journal Article
    ​ ​Structural basis for CRM1 nuclear export complex assembly​
    Monecke, T. ; Güttler, T.; Neumann, P. ; Doelker, N.; Blanchet, C.; Dickmanns, A.   & Görlich, D. et al.​ (2010) 
    Acta Crystallographica. Section A, Foundations and Advances, 66(a1) pp. s30​-s31​.​ DOI: https://doi.org/10.1107/S0108767310099319 
    ​Details  DOI 
  • 2010 | Journal Article | Research Paper
    ​ ​NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1​
    Guettler, T.; Madl, T.; Neumann, P. ; Deichsel, D.; Corsini, L.; Monecke, T.   & Ficner, R.  et al.​ (2010) 
    Nature Structural & Molecular Biology, 17(11) pp. 1367​-U229​.​ DOI: https://doi.org/10.1038/nsmb.1931 
    ​Details  DOI  PMID  PMC  WoS 
  • 2009 | Journal Article | Research Paper
    ​ ​Structural basis for m(7)G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1​
    Monecke, T. ; Dickmanns, A.   & Ficner, R. ​ (2009) 
    Nucleic Acids Research, 37(12) pp. 3865​-3877​.​ DOI: https://doi.org/10.1093/nar/gkp249 
    ​Details  DOI  PMID  PMC  WoS 
  • 2009 | Journal Article | Research Paper
    ​ ​Structure analysis of the conserved methyltransferase domain of human trimethylguanosine synthase TGS1​
    Monecke, T. ; Dickmanns, A. ; Strasser, A. & Ficner, R. ​ (2009) 
    Acta Crystallographica Section D Biological Crystallography, 65 pp. 332​-338​.​ DOI: https://doi.org/10.1107/S0907444909003102 
    ​Details  DOI  PMID  PMC  WoS 
  • 2009 | Journal Article | Research Paper
    ​ ​Crystal Structure of the Nuclear Export Receptor CRM1 in Complex with Snurportin1 and RanGTP​
    Monecke, T. ; Guettler, T.; Neumann, P. ; Dickmanns, A. ; Goerlich, D. & Ficner, R. ​ (2009) 
    Science, 324(5930) pp. 1087​-1091​.​ DOI: https://doi.org/10.1126/science.1173388 
    ​Details  DOI  PMID  PMC  WoS 
  • 2008 | Journal Article | Research Paper
    ​ ​Crystal structure of the RRM domain of poly(A)-specific ribonuclease reveals a novel m(7)G-cap-binding mode​
    Monecke, T. ; Schell, S.; Dickmanns, A.   & Ficner, R. ​ (2008) 
    Journal of Molecular Biology, 382(4) pp. 827​-834​.​ DOI: https://doi.org/10.1016/j.jmb.2008.07.073 
    ​Details  DOI  PMID  PMC  WoS 

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