Prof. Dr. med. Roland Nau

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  • 2023 | Journal Article | 
    ​ ​Serological testing for syphilis in the differential diagnosis of cognitive decline and polyneuropathy in geriatric patients​
    Djukic, M.; Eiffert, H.; Lange, P.; Giotaki, I.; Seele, J. & Nau, R. ​ (2023) 
    BMC Geriatrics, 23(1) art. 274​.​ DOI: https://doi.org/10.1186/s12877-023-03981-4 
    ​Details  DOI 
  • 2023 | Journal Article | 
    ​ ​Septic encephalopathy in the elderly – biomarkers of potential clinical utility​
    Schütze, S.; Drevets, D. A.; Tauber, S. C. & Nau, R. ​ (2023) 
    Frontiers in Cellular Neuroscience, 17 art. 1238149​.​ DOI: https://doi.org/10.3389/fncel.2023.1238149 
    ​Details  DOI 
  • 2023 | Journal Article | 
    ​ ​Ceftriaxone‐induced neutropenia successfully overcome by a switch to penicillin G in Cardiobacterium hominis endocarditis​
    Nau, R. ; Schmidt‐Schweda, S.; Frank, T.; Gossner, J.; Djukic, M. & Eiffert, H.​ (2023) 
    Clinical Case Reports, 11(6) art. e7462​.​ DOI: https://doi.org/10.1002/ccr3.7462 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Spatial and temporal variation of routine parameters: pitfalls in the cerebrospinal fluid analysis in central nervous system infections​
    Djukic, M. ; Lange, P. ; Erbguth, F. & Nau, R. ​ (2022) 
    Journal of Neuroinflammation, 19(1) art. 174​.​ DOI: https://doi.org/10.1186/s12974-022-02538-3 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper
    ​ ​Reducing the use of sleep-inducing drugs during hospitalisation by a multi-faceted intervention: a pilot study​
    Klemperer, J.; Himmel, W. ; Heinemann, S. ; Hummers, E.   & Nau, R. ​ (2022) 
    European Journal of Hospital Pharmacy, Online ahead of print pp. ejhpharm-2021-003097​.​ DOI: https://doi.org/10.1136/ejhpharm-2021-003097 
    ​Details  DOI  PMID  PMC 
  • 2022 | Journal Article | Research Paper | 
    ​ ​Chronic Candida albicans meningitis misdiagnosed as polymyalgia rheumatica and successfully treated with voriconazole​
    Giotaki, I.; Gross, U. ; Lange, P. ; Rustenbeck, H.-H. ; Bahn, E.   & Nau, R. ​ (2022) 
    Clinical Case Reports, 10(4).​ DOI: https://doi.org/10.1002/ccr3.5664 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Central nervous system infections and antimicrobial resistance: an evolving challenge​
    Nau, R. ; Sörgel, F. & Eiffert, H. ​ (2021) 
    Current Opinion in Neurology, 34(3) pp. 456​-467​.​ DOI: https://doi.org/10.1097/WCO.0000000000000931 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​COVID-19 im Alter – Die geriatrische Perspektive​
    Wirth, R.; Becker, C. ; Djukic, M. ; Drebenstedt, C.; Heppner, H. J.; Jacobs, A. H. & Meisel, M. et al.​ (2021) 
    Zeitschrift für Gerontologie und Geriatrie, 54(2) pp. 152​-160​.​ DOI: https://doi.org/10.1007/s00391-021-01864-0 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Host Age and Denture Wearing Jointly Contribute to Oral Colonization with Intrinsically Azole-Resistant Yeasts in the Elderly​
    Wojak, K.-P.; Ungermann, G. F.; Ichsan, I.; Gomez-Molero, E.; Jung, K. ; Weig, M.   & Nauck, F.  et al.​ (2021) 
    Microorganisms, 9(8) pp. 1627​.​ DOI: https://doi.org/10.3390/microorganisms9081627 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Sepsis-associated encephalopathy and septic encephalitis: an update​
    Tauber, S. C.; Djukic, M. ; Gossner, J.; Eiffert, H. ; Brück, W.   & Nau, R. ​ (2020) 
    Expert Review of Anti-infective Therapy, 19(2) pp. 215​-231​.​ DOI: https://doi.org/10.1080/14787210.2020.1812384 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​HIF-1α is involved in blood–brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis​
    Devraj, G.; Guérit, S.; Seele, J.; Spitzer, D.; Macas, J.; Khel, M. I. & Heidemann, R. et al.​ (2020) 
    Acta Neuropathologica, 140(2) pp. 183​-208​.​ DOI: https://doi.org/10.1007/s00401-020-02174-2 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Searching for Antipneumococcal Targets: Choline-Binding Modules as Phagocytosis Enhancers​
    Roig-Molina, E.; Sánchez-Angulo, M.; Seele, J.; García-Asencio, F.; Nau, R. ; Sanz, J. M. & Maestro, B.​ (2020) 
    ACS Infectious Diseases, 6(5) pp. 954​-974​.​ DOI: https://doi.org/10.1021/acsinfecdis.9b00344 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​Intrathecal Antibacterial and Antifungal Therapies​
    Nau, R. ; Blei, C. & Eiffert, H. ​ (2020) 
    Clinical Microbiology Reviews, 33(3).​ DOI: https://doi.org/10.1128/CMR.00190-19 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Pre-treatment with the viral Toll-like receptor 3 agonist poly(I:C) modulates innate immunity and protects neutropenic mice infected intracerebrally with Escherichia coli​
    Ribes, S. ; Arcilla, C.; Ott, M.; Schütze, S.; Hanisch, U.-K. ; Nessler, S.   & Nau, R. ​ (2020) 
    Journal of Neuroinflammation, 17(1).​ DOI: https://doi.org/10.1186/s12974-020-1700-4 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Neurogeriatrie – eine Vision für die verbesserte Versorgung und Forschung für geriatrische Patienten mit führend neurologischen Erkrankungen​
    Jacobs, A. H.; Emmert, K.; Baron, R.; Bartsch, T.; Bauer, J.; Becker, C. & Berg, D.  et al.​ (2020) 
    Zeitschrift für Gerontologie und Geriatrie, 53(4) pp. 340​-346​.​ DOI: https://doi.org/10.1007/s00391-020-01734-1 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Antimicrobial and Immunomodulatory Effect of Gum Arabic on Human and Bovine Granulocytes Against Staphylococcus aureus and Escherichia coli​
    Baien, S. H.; Seele, J.; Henneck, T.; Freibrodt, C.; Szura, G.; Moubasher, H. & Nau, R.  et al.​ (2020) 
    Frontiers in Immunology, 10.​ DOI: https://doi.org/10.3389/fimmu.2019.03119 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Training improves the handling of inhaler devices and reduces the severity of symptoms in geriatric patients suffering from chronic-obstructive pulmonary disease​
    Luley, M.-C.; Loleit, T.; Knopf, E.; Djukic, M. ; Criée, C.-P. & Nau, R. ​ (2020) 
    BMC Geriatrics, 20(1).​ DOI: https://doi.org/10.1186/s12877-020-01804-4 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Comparing Cathelicidin Susceptibility of the Meningitis Pathogens Streptococcus suis and Escherichia coli in Culture Medium in Contrast to Porcine or Human Cerebrospinal Fluid​
    Meurer, M.; de Buhr, N.; Unger, L. M.; Bonilla, M. C.; Seele, J.; Nau, R.   & Baums, C. G. et al.​ (2020) 
    Frontiers in Microbiology, 10.​ DOI: https://doi.org/10.3389/fmicb.2019.02911 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Reply: Neither human nor mouse is hypercalcaemic with 250 nmol/l 25-hydroxyvitamin D​
    Häusler, D.; Torke, S.; Peelen, E.; Bertsch, T.; Weber, M.; Heilmann, M. & Djukic, M.  et al.​ (2019) 
    Brain: A Journal of Neurology, 143(2) pp. e10​-e10​.​ DOI: https://doi.org/10.1093/brain/awz389 
    ​Details  DOI 
  • 2019 | Journal Article | Research Paper | 
    ​ ​Aged mice show an increased mortality after anesthesia with a standard dose of ketamine/xylazine​
    Schütze, S.; Manig, A.; Ribes, S.   & Nau, R. ​ (2019) 
    Laboratory Animal Research, 35(1) art. 8​.​ DOI: https://doi.org/10.1186/s42826-019-0008-y 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Introduction of Non-Vitamin K Antagonist Anticoagulants Strongly Increased the Rate of Anticoagulation in Hospitalized Geriatric Patients with Atrial Fibrillation​
    Djukic, M. ; Braun, L. M.; Unkel, S. ; Jacobshagen, C.   & Nau, R. ​ (2018) 
    Drugs & Aging, 35(9) pp. 859​-869​.​ DOI: https://doi.org/10.1007/s40266-018-0571-1 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Pharmacokinetics and pharmacodynamics of antibiotics in central nervous system infections​
    Nau, R. ; Seele, J.; Djukic, M.   & Eiffert, H. ​ (2018) 
    Current Opinion in Infectious Diseases, 31(1) pp. 57​-68​.​ DOI: https://doi.org/10.1097/QCO.0000000000000418 
    ​Details  DOI 
  • 2018 | Journal Article
    ​ ​Cisterno-lumbar gradient of complement fractions in geriatric patients with suspected normal pressure hydrocephalus​
    Seele, J.; Kirschfink, M.; Djukic, M. ; Lange, P. ; Gossner, J.; Bunkowski, S.   & Wiltfang, J.  et al.​ (2018) 
    Clinica Chimica Acta, 486 pp. 1​-7​.​ DOI: https://doi.org/10.1016/j.cca.2018.07.008 
    ​Details  DOI 
  • 2017 | Journal Article | Research Paper | 
    ​ ​High prevalence of prescription of psychotropic drugs for older patients in a general hospital​
    Arnold, I.; Straube, K.; Himmel, W. ; Heinemann, S. ; Weiß, V. ; Heyden, L. M.   & Hummers-Pradier, E.  et al.​ (2017) 
    BMC Pharmacology & Toxicology, 18(1) art. 76​.​ DOI: https://doi.org/10.1186/s40360-017-0183-0 
    ​Details  DOI 
  • 2017 | Journal Article
    ​ ​Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation​
    Hupp, S.; Ribes, S. ; Seele, J.; Bischoff, C.; Förtsch, C.; Maier, E. & Benz, R. et al.​ (2017) 
    British Journal of Pharmacology, 174(23) pp. 4295​-4307​.​ DOI: https://doi.org/10.1111/bph.v174.23 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Septic encephalopathy and septic encephalitis‬‬​
    Tauber, S. C.; Eiffert, H. ; Brück, W.   & Nau, R. ​ (2016) 
    Expert Review of Anti-infective Therapy, 15(2) pp. 121​-132​.​ DOI: https://doi.org/10.1080/14787210.2017.1265448 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Ambulant erworbene bakterielle (eitrige) Meningoenzephalitis im Erwachsenenalter​
    Klein, M.; Bühler, R.; Eiffert, H. ; Grabein, B.; Linn, J.; Nau, R.   & Salzberger, B. et al.​ (2016) 
    Aktuelle Neurologie, 43(06) pp. 358​-368​.​ DOI: https://doi.org/10.1055/s-0042-110434 
    ​Details  DOI 
  • 2016 | Journal Article
    ​ ​Infections in the differential diagnosis of Bell’s palsy: a plea for performing CSF analysis​
    Henkel, K.; Lange, P. ; Eiffert, H. ; Nau, R.   & Spreer, A. ​ (2016) 
    Infection, 45(2) pp. 147​-155​.​ DOI: https://doi.org/10.1007/s15010-016-0933-8 
    ​Details  DOI 
  • 2016 | Journal Article | 
    ​ ​Astrocytes Enhance Streptococcus suis-Glial Cell Interaction in Primary Astrocyte-Microglial Cell Co-Cultures​
    Seele, J.; Nau, R. ; Prajeeth, C.; Stangel, M.; Valentin-Weigand, P. & Seitz, M.​ (2016) 
    Pathogens, 5(2) pp. 43​.​ DOI: https://doi.org/10.3390/pathogens5020043 
    ​Details  DOI 
  • 2016 | Journal Article | 
    ​ ​Small cisterno-lumbar gradient of phosphorylated Tau protein in geriatric patients with suspected normal pressure hydrocephalus​
    Djukic, M. ; Spreer, A. ; Lange, P. ; Bunkowski, S. ; Wiltfang, J.   & Nau, R. ​ (2016) 
    Fluids and Barriers of the CNS, 13(1) art. 15​.​ DOI: https://doi.org/10.1186/s12987-016-0039-9 
    ​Details  DOI  PMID  PMC 
  • 2015 | Journal Article | 
    ​ ​Beneficial effect of chronic Staphylococcus aureus infection in a model of multiple sclerosis is mediated through the secretion of extracellular adherence protein​
    Kumar, P.; Kretzschmar, B.; Herold, S.; Nau, R. ; Kreutzfeldt, M.; Schütze, S. & Bähr, M.  et al.​ (2015) 
    Journal of Neuroinflammation, 12(1) art. 22​.​ DOI: https://doi.org/10.1186/s12974-015-0241-8 
    ​Details  DOI 
  • 2015 | Journal Article | Research Paper | 
    ​ ​Systemic Escherichia coli infection does not influence clinical symptoms and neurodegeneration in experimental autoimmune encephalomyelitis​
    Kumar, P.; Friebe, K.; Schallhorn, R.; Moinfar, Z.; Nau, R. ; Bähr, M.   & Schütze, S. et al.​ (2015) 
    BMC Neuroscience, 16 art. 36​.​ DOI: https://doi.org/10.1186/s12868-015-0172-4 
    ​Details  DOI  PMID  PMC  WoS 
  • 2014 | Journal Article
    ​ ​Fungal encephalitis in human autopsy cases is associated with extensive neuronal damage but only minimal repair​
    Tauber, S. C.; Eiffert, H. ; Kellner, S.; Lugert, R. ; Bunkowski, S. ; Schuetze, S. & Perske, C.  et al.​ (2014) 
    Neuropathology and Applied Neurobiology, 40(5) pp. 610​-627​.​ DOI: https://doi.org/10.1111/nan.12044 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Conference Abstract
    ​ ​Additive microglial-mediated neuronal injury induced by Amyloid-beta and bacterial TLR agonists​
    Ebert, S.; Loleit, T.; Zeretzke, M.; Bunkowski, S. ; Ribes, S.   & Nau, R. ​ (2010)
    Journal of Neuroimmunology, 228(1-2) ​10th Congress of the International-Society-of-Neuroimmunology (ISNI)​, Sitges, SPAIN.
    Amsterdam​: Elsevier Science Bv.
    ​Details  WoS 
  • 2006 | Journal Article | Letter Note
    ​ ​Varicella zoster virus cerebellitis in a 66-year-old patient without herpes zoster​
    Ratzka, P. ; Schlachetzki, J. C. M.; Bähr, M.   & Nau, R. ​ (2006) 
    The Lancet, 367(9505).​ DOI: https://doi.org/10.1016/S0140-6736(06)67967-1 
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Journal Article | Research Paper
    ​ ​Limited protection of TAT-Bcl-X-L against pneumolysin-induced neuronal cell death​
    Ebert, S.; Dietz, G. P. H. ; Mitchell, T. J.; Michel, U. ; Bähr, M.   & Nau, R. ​ (2005) 
    Neuroscience Letters, 384(3) pp. 349​-353​.​ DOI: https://doi.org/10.1016/j.neulet.2005.05.027 
    ​Details  DOI  PMID  PMC  WoS 
  • 2004 | Journal Article
    ​ ​Clindamycin is neuroprotective in experimental Streptococcus pneumoniae meningitis compared with ceftriaxone​
    Böttcher, T.; Ren, H.; Goiny, M.; Gerber, J.; Lykkesfeldt, J.; Kuhnt, U. & Lotz, M. et al.​ (2004) 
    Journal of Neurochemistry, 91(6) pp. 1450​-1460​.​ DOI: https://doi.org/10.1111/j.1471-4159.2004.02837.x 
    ​Details  DOI  PMID  PMC  WoS 
  • 2003 | Journal Article
    ​ ​Immune response to capsular polysaccharide and surface proteins of Streptococcus pneumoniae in patients with invasive pneumococcal disease​
    Zysk, G.; Bethe, G.; Nau, R. ; Koch, D.; Gräfin von Bassewitz, V. C. D. H.; Heinz, H.-P. & Reinert, R. R.​ (2003) 
    The Journal of Infectious Diseases, 187(2) pp. 330​-333​.​ DOI: https://doi.org/10.1086/367701 
    ​Details  DOI  PMID  PMC  WoS 
  • 2002 | Conference Paper | Research Paper
    ​ ​Neurotoxicity of pneumolysin, a major pneumococcal virulence factor, involves calcium influx and depends on activation of p38 mitogen-activated protein kinase​
    Stringaris, A.; Geisenhainer, J.; Bergmann, F. ; Balshusemann, C.; Lee, U.; Zysk, G. & Mitchell, T. J. et al.​ (2002)
    ​Neurobiology of Disease (3) pp. 355​-368. (Vol. 11). ​54th Annual Meeting of the American-Academy-of-Neurology​, DENVER, COLORADO.
    San diego​: Academic Press Inc Elsevier Science. DOI: https://doi.org/10.1006/nbdi.2002.0561 
    ​Details  DOI  PMID  PMC  WoS 
  • 2000 | Journal Article
    ​ ​Glutamine synthetase in experimental meningitis: increased ratio of the subunits 3 and 2 may indicate enhanced activity​
    Smirnov, A. V. ; Tumani, H. ; Henne, S. ; Barchfeld, S. ; Olgemöller, U. ; Wiltfang, J.   & Lange, P.  et al.​ (2000) 
    Clinica Chimica Acta, 292(1-2) pp. 1​-12​.​ DOI: https://doi.org/10.1016/s0009-8981(99)00180-1 
    ​Details  DOI  PMID  PMC 
  • 1999 | Journal Article
    ​ ​Intravenous Granulocyte Colony-Stimulating Factor Increases the Release of Tumour Necrosis Factor and Interleukin-1beta into the Cerebrospinal Fluid, But Does Not Inhibit the Growth of Streptococcus pneumoniae in Experimental Meningitis​
    Schmidt, H.; Stuertz, K.; Brück, W.; Chen, V.; Stringaris, A. K.; Fischer, F. R. & Nau, R. ​ (1999) 
    Scandinavian Journal of Immunology, 49(5) pp. 481​-486​.​ DOI: https://doi.org/10.1046/j.1365-3083.1999.00518.x 
    ​Details  DOI 

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