Prof. Dr. Nils Brose

Name Card

Main Affiliation

Max-Planck-Institut für Experimentelle Medizin

Staff Status

unigoe

Sorry, an error occured!
Please use the before the publication to edit your data.

Sorry, it is not allowed to delete your data.

1-247 of 247

The bibliographical data in your publication list are complete

You can correct existing data in the blue highlighted fields.To do this, please click on the coloured field. It is not possible to delete data here.
Fields that are not marked in colour (e. g. the authors) can be edited using the input form. To do so, click on the in front of the respective publication.

The bibliographic data in your publication list may be incomplete. You can

add any missing data in the fields marked in red or
correct existing data in the blue highlighted fields.

To do this, please click on the coloured field. It is not possible to delete data here.
Fields that are not marked in colour (e. g. the authors) can be edited using the input form. To do so, click on the in front of the respective publication.

Check/Uncheck all

2023 | Journal Article
Characterizing the differential distribution and targets of Sumo1 and Sumo2 in the mouse brain
Suk, T. R.; Nguyen, T. T.; Fisk, Z. A.; Mitkovski, M.; Geertsma, H. M.; Parmasad, J. Parmasad, Jean-Louis A. & Heer, M. M. et al. (2023)
iScience, 26(4) art. 106350. DOI: https://doi.org/10.1016/j.isci.2023.106350
Details DOI PMID PMC

2022 | Journal Article | Research Paper
Molecular and functional architecture of striatal dopamine release sites
Banerjee, A.; Imig, C.; Balakrishnan, K.; Kershberg, L.; Lipstein, N.; Uronen, R.-L. & Wang, J. et al. (2022)
Neuron, 110(2) pp. 248.e9-265.e9. DOI: https://doi.org/10.1016/j.neuron.2021.10.028
Details DOI PMID PMC

2022 | Preprint
Functional Neuroligin-2-MDGA1 interactions differentially regulate synaptic GABAARs and cytosolic gephyrin aggregation
Zeppillo, T.; Ali, H.; Wenger, S.; Lopez Murcia, F. J.; Gideons, E.; Signorelli, J.& Schmeisser, M. J. et al. (2022). DOI: https://doi.org/10.1101/2022.08.08.503083
Details DOI

2022 | Preprint
Phosphorylation Determines Whether Neuroligin-3 is at Excitatory or Inhibitory Synapses in Different Regions of the Brain
Altas, B.; Tuffy, L. P.; Patrizi, A.; Dimova, K.; Soykan, T.; Romanowski, A. J.& Robertson, C. D. et al. (2022). DOI: https://doi.org/10.1101/2022.07.23.501257
Details DOI

2022 | Journal Article |
Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones
Tan, C.; de Nola, G.; Qiao, C.; Imig, C.; Born, R. T.; Brose, N. & Kaeser, P. S. (2022)
eLife, 11 art. e79077. DOI: https://doi.org/10.7554/eLife.79077
Details DOI PMID PMC

2022 | Journal Article | Research Paper |
A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution
Elizarova, S.; Chouaib, A. A.; Shaib, A.; Hill, B.; Mann, F.; Brose, N. & Kruss, S. et al. (2022)
Proceedings of the National Academy of Sciences, 119(22) art. e2202842119. DOI: https://doi.org/10.1073/pnas.2202842119
Details DOI PMID PMC

2021 | Preprint
A fluorescent nanosensor paint reveals the heterogeneity of dopamine release from neurons at individual release sites
Elizarova, S.; Chouaib, A.; Shaib, A.; Mann, F.; Brose, N. ; Kruss, S.& Daniel, J. A. (2021). DOI: https://doi.org/10.1101/2021.03.28.437019
Details DOI

2021 | Journal Article
Two Functional Epithelial Sodium Channel Isoforms Are Present in Rodents despite Pronounced Evolutionary Pseudogenization and Exon Fusion
Gettings, S. M.; Maxeiner, S.; Tzika, M.; Cobain, M. R. D.; Ruf, I.; Benseler, F. & Brose, N. et al. (2021)
Molecular Biology and Evolution, 38(12) pp. 5704-5725. DOI: https://doi.org/10.1093/molbev/msab271
Details DOI

2021 | Journal Article
The α3 subunit of GABAA receptors promotes formation of inhibitory synapses in the absence of collybistin
Wagner, S.; Lee, C.; Rojas, L.; Specht, C. G.; Rhee, J.; Brose, N. & Papadopoulos, T. (2021)
Journal of Biological Chemistry, 296 pp. 100709. DOI: https://doi.org/10.1016/j.jbc.2021.100709
Details DOI

2021 | Journal Article
Tmem160 contributes to the establishment of discrete nerve injury-induced pain behaviors in male mice
Segelcke, D.; Fischer, H. K.; Hütte, M.; Dennerlein, S.; Benseler, F.; Brose, N. & Pogatzki-Zahn, E. M. et al. (2021)
Cell Reports, 37(12) art. S221112472101648X. DOI: https://doi.org/10.1016/j.celrep.2021.110152
Details DOI

2021 | Journal Article |
Synaptotagmin-7 places dense-core vesicles at the cell membrane to promote Munc13-2- and Ca2+-dependent priming
Tawfik, B.; Martins, J. S.; Houy, S.; Imig, C.; Pinheiro, P. S.; Wojcik, S. M. & Brose, N. et al. (2021)
eLife, 10. DOI: https://doi.org/10.7554/eLife.64527
Details DOI

2021 | Journal Article | Research Paper |
Munc13-1 is a Ca2+-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission
Lipstein, N.; Chang, S.; Lin, K.-H.; López-Murcia, F. J.; Neher, E. ; Taschenberger, H. & Brose, N. (2021)
Neuron, 109(24) pp. 3980-4000.e7. DOI: https://doi.org/10.1016/j.neuron.2021.09.054
Details DOI PMID PMC

2020 | Preprint
Molecular and functional architecture of striatal dopamine release sites
Banerjee, A.; Imig, C.; Balakrishnan, K.; Kershberg, L.; Lipstein, N.; Uronen, R.-L.& Wang, J. et al. (2020). DOI: https://doi.org/10.1101/2020.11.25.398255
Details DOI

2020 | Journal Article
The Synaptic Vesicle Priming Protein CAPS-1 Shapes the Adaptation of Sensory Evoked Responses in Mouse Visual Cortex
Nestvogel, D. B.; Merino, R. M.; Leon-Pinzon, C.; Schottdorf, M. ; Lee, C.; Imig, C. & Brose, N. et al. (2020)
Cell Reports, 30(10) pp. 3261-3269.e4. DOI: https://doi.org/10.1016/j.celrep.2020.02.045
Details DOI

2020 | Journal Article
Vesicular Glutamate Transporter Expression Ensures High-Fidelity Synaptic Transmission at the Calyx of Held Synapses
Nakakubo, Y.; Abe, S.; Yoshida, T.; Takami, C.; Isa, M.; Wojcik, S. M. & Brose, N. et al. (2020)
Cell Reports, 32(7) art. S2211124720310251. DOI: https://doi.org/10.1016/j.celrep.2020.108040
Details DOI

2020 | Journal Article
Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents
Maxeiner, S.; Benseler, F.; Krasteva-Christ, G.; Brose, N. & Südhof, T. C (2020)
Molecular Biology and Evolution, 37(5) pp. 1243-1258. DOI: https://doi.org/10.1093/molbev/msaa014
Details DOI

2020 | Journal Article | Research Paper |
Neuroligin-2 dependent conformational activation of collybistin reconstituted in supported hybrid membranes
Schäfer, J. ; Förster, L.; Mey, I. ; Papadopoulos, T. ; Brose, N. & Steinem, C. (2020)
Journal of Biological Chemistry, 295(52) pp. 18604-18613. DOI: https://doi.org/10.1074/jbc.RA120.015347
Details DOI PMID PMC

2020 | Journal Article | Research Paper |
Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses
Maus, L.; Lee, C.; Altas, B.; Sertel, S. M.; Weyand, K.; Rizzoli, S. O. & Rhee, J. et al. (2020)
Cell Reports, 30(11) pp. 3632-3643.e8. DOI: https://doi.org/10.1016/j.celrep.2020.02.083
Details DOI PMID PMC

2020 | Journal Article | Research Paper |
SUMOylation controls the neurodevelopmental function of the transcription factor Zbtb20
Ripamonti, S.; Shomroni, O. ; Rhee, J. S. ; Chowdhury, K.; Jahn, O. ; Hellmann, K. P. & Bonn, S. et al. (2020)
Journal of Neurochemistry, 154(6) pp. 647-661. DOI: https://doi.org/10.1111/jnc.15008
Details DOI PMID PMC

2020 | Journal Article | Research Paper |
Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices
Imig, C.; López-Murcia, F. J.; Maus, L.; García-Plaza, I. H.; Mortensen, L. S.; Schwark, M. & Schwarze, V. et al. (2020)
Neuron, 108(5) pp. 843-860.e8. DOI: https://doi.org/10.1016/j.neuron.2020.09.004
Details DOI PMID PMC

2019 | Journal Article
Synaptic vesicle fusion: today and beyond
Brose, N. ; Brunger, A.; Cafiso, D.; Chapman, E. R.; Diao, J.; Hughson, F. M. & Jackson, M. B. et al. (2019)
Nature Structural & Molecular Biology, 26(8) pp. 663-668. DOI: https://doi.org/10.1038/s41594-019-0277-z
Details DOI

2019 | Journal Article
Dynamic Control of Vesicle Priming in Synaptic Short-Term Plasticity
Brose, N. (2019)
Biophysical Journal, 116(3) pp. 10a. DOI: https://doi.org/10.1016/j.bpj.2018.11.092
Details DOI

2019 | Preprint
Correlating Synaptic Ultrastructure and Function at the Nanoscale
Maus, L.; Altas, B.; Rhee, J.; Brose, N. ; Imig, C.& Cooper, B. H. (2019). DOI: https://doi.org/10.1101/588848
Details DOI

2019 | Journal Article
Complexin cooperates with Bruchpilot to tether synaptic vesicles to the active zone cytomatrix
Scholz, N.; Ehmann, N.; Sachidanandan, D.; Imig, C.; Cooper, B. H. ; Jahn, O. & Reim, K. et al. (2019)
The Journal of Cell Biology, 218(3) pp. 1011-1026. DOI: https://doi.org/10.1083/jcb.201806155
Details DOI

2019 | Journal Article |
Acute Complexin Knockout Abates Spontaneous and Evoked Transmitter Release
López-Murcia, F. J.; Reim, K.; Jahn, O. ; Taschenberger, H. & Brose, N. (2019)
Cell Reports, 26(10) art. 2530.e5. DOI: https://doi.org/10.1016/j.celrep.2019.02.030
Details DOI PMID PMC

2019 | Journal Article
SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse
Koopmans, F.; van Nierop, P.; Andres-Alonso, M.; Byrnes, A.; Cijsouw, T.; Coba, M. P. & Cornelisse, L. N. et al. (2019)
Neuron, 103(2) pp. 217-234. DOI: https://doi.org/10.1016/j.neuron.2019.05.002
Details DOI PMID PMC

2018 | Journal Article
Response: Commentary: Analysis of SUMO1-conjugation at synapses
Daniel, J. A.; Cooper, B. H.; Palvimo, J. J.; Zhang, F.-P.; Brose, N. & Tirard, M. (2018)
Frontiers in Cellular Neuroscience, 12. DOI: https://doi.org/10.3389/fncel.2018.00117
Details DOI

2018 | Journal Article
Dynamically Primed Synaptic Vesicle States: Key to Understand Synaptic Short-Term Plasticity
Neher, E. & Brose, N. (2018)
Neuron, 100(6) pp. 1283-1291. DOI: https://doi.org/10.1016/j.neuron.2018.11.024
Details DOI

2018 | Journal Article
Deletion of LRRTM1 and LRRTM2 in adult mice impairs basal AMPA receptor transmission and LTP in hippocampal CA1 pyramidal neurons
Bhouri, M.; Morishita, W.; Temkin, P.; Goswami, D.; Kawabe, H.; Brose, N. & Südhof, T. C. et al. (2018)
Proceedings of the National Academy of Sciences, 115(23) pp. E5382-E5389. DOI: https://doi.org/10.1073/pnas.1803280115
Details DOI

2018 | Journal Article
Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses
Zhang, B.; Gokce, O.; Hale, W. D.; Brose, N. & Südhof, T. C. (2018)
Journal of Experimental Medicine, 215(6) pp. 1543-1553. DOI: https://doi.org/10.1084/jem.20172162
Details DOI

2018 | Journal Article
BACE1 inhibition more effectively suppresses initiation than progression of β-amyloid pathology
Peters, F.; Salihoglu, H.; Rodrigues, E. ; Herzog, E.; Blume, T.; Filser, S. & Dorostkar, M. et al. (2018)
Acta Neuropathologica, 135(5) pp. 695-710. DOI: https://doi.org/10.1007/s00401-017-1804-9
Details DOI

2018 | Journal Article | Research Paper |
IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses
Babaev, O.; Cruces-Solis, H.; Piletti Chatain, C.; Hammer, M.; Wenger, S.; Ali, H. & Karalis, N. et al. (2018)
Nature Communications, 9(1) art. 5400. DOI: https://doi.org/10.1038/s41467-018-07762-1
Details DOI PMID PMC

2017 | Journal Article
Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder
Lipstein, N.; Verhoeven-Duif, N. M.; Michelassi, F. E.; Calloway, N.; van Hasselt, P. M.; Pienkowska, K. & van Haaften, G. et al. (2017)
The Journal of Clinical Investigation, 127(3) pp. 1005-1018. DOI: https://doi.org/10.1172/JCI90259
Details DOI

2017 | Journal Article
Synapse biology in the ‘circuit-age’—paths toward molecular connectomics
Schreiner, D.; Savas, J. N.; Herzog, E.; Brose, N. & de Wit, J. (2017)
Current Opinion in Neurobiology, 42 pp. 102-110. DOI: https://doi.org/10.1016/j.conb.2016.12.004
Details DOI

2017 | Journal Article
A novel Munc13-4/S100A10/annexin A2 complex promotes Weibel–Palade body exocytosis in endothelial cells
Chehab, T.; Santos, N. C.; Holthenrich, A.; Koerdt, S. N.; Disse, J.; Schuberth, C. & Nazmi, A. R. et al. (2017)
Molecular Biology of the Cell, 28(12) pp. 1688-1700. DOI: https://doi.org/10.1091/mbc.E17-02-0128
Details DOI

2017 | Journal Article
Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex
Unichenko, P.; Yang, J.-W.; Kirischuk, S.; Kolbaev, S.; Kilb, W.; Hammer, M. & Krueger-Burg, D. et al. (2017)
Cerebral Cortex, pp. 1-14. DOI: https://doi.org/10.1093/cercor/bhx165
Details DOI

2017 | Journal Article
Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release
Sigler, A.; Oh, W. C.; Imig, C.; Altas, B.; Kawabe, H.; Cooper, B. H. & Kwon, H.-B. et al. (2017)
Neuron, 94(2) pp. 304-311.e4. DOI: https://doi.org/10.1016/j.neuron.2017.03.029
Details DOI

2017 | Journal Article
Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18
Lai, Y.; Choi, U. B.; Leitz, J.; Rhee, H. J.; Lee, C.; Altas, B. & Zhao, M. et al. (2017)
Neuron, 95(3) pp. 591-607.e10. DOI: https://doi.org/10.1016/j.neuron.2017.07.004
Details DOI

2017 | Conference Abstract
Apparent Ca2+-dependence of vesicle recruitment with two pools of vesicles
Ritzau-Jost, A.; Viotti, J.; Brose, N. & Hallermann, S. (2017)
Acta Physiologica, 219
Hoboken: Wiley.
Details WoS

2017 | Journal Article
Blood RNA biomarkers in prodromal PARK4 and rapid eye movement sleep behavior disorder show role of complexin 1 loss for risk of Parkinson's disease
Lahut, S.; Gispert, S.; Ömür, Ö.; Depboylu, C.; Seidel, K.; Domínguez-Bautista, J. A. & Brehm, N. et al. (2017)
Disease Models & Mechanisms, 10(5) pp. 619-631. DOI: https://doi.org/10.1242/dmm.028035
Details DOI

2017 | Journal Article |
Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons
Ripamonti, S.; Ambrozkiewicz, M. C.; Guzzi, F.; Gravati, M.; Biella, G.; Bormuth, I. & Hammer, M. et al. (2017)
eLife, 6. DOI: https://doi.org/10.7554/eLife.22466
Details DOI

2017 | Journal Article |
Analysis of SUMO1-conjugation at synapses
Daniel, J. A.; Cooper, B. H. ; Palvimo, J. J.; Zhang, F.-P.; Brose, N. & Tirard, M. (2017)
eLife, 6. DOI: https://doi.org/10.7554/eLife.26338
Details DOI

2017 | Journal Article
ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones
Kawabe, H.; Mitkovski, M.; Kaeser, P. S.; Hirrlinger, J. ; Opazo, F. ; Nestvogel, D. & Kalla, S. et al. (2017)
The Journal of Cell Biology, 216(4) pp. 1143-1161. DOI: https://doi.org/10.1083/jcb.201606086
Details DOI PMID PMC

2017 | Journal Article | Research Paper |
Endosomal Phosphatidylinositol 3-Phosphate Promotes Gephyrin Clustering and GABAergic Neurotransmission at Inhibitory Postsynapses
Papadopoulos, T. ; Rhee, H. J.; Subramanian, D.; Paraskevopoulou, F.; Mueller, R.; Schultz, C. & Brose, N. et al. (2017)
Journal of Biological Chemistry, 292(4) pp. 1160-1177. DOI: https://doi.org/10.1074/jbc.M116.771592
Details DOI PMID PMC

2017 | Journal Article | Overview
Organizers of inhibitory synapses come of age
Krueger-Burg, D. ; Papadopoulos, T. & Brose, N. (2017)
Current Opinion in Neurobiology, 45 pp. 66-77. DOI: https://doi.org/10.1016/j.conb.2017.04.003
Details DOI PMID PMC

2016 | Journal Article
Hair cell synaptic dysfunction, auditory fatigue and thermal sensitivity in otoferlin Ile515Thr mutants
Strenzke, N. ; Chakrabarti, R. ; Al‐Moyed, H. ; Müller, A. ; Hoch, G. ; Pangrsic, T. & Yamanbaeva, G. et al. (2016)
EMBO Journal, 35(23) pp. 2519-2535. DOI: https://doi.org/10.15252/embj.201694564
Details DOI

2016 | Journal Article
Neuroligin-family synaptic adhesion proteins in autism spectrum disorders
Brose, N. (2016)
European Neuropsychopharmacology, 26 pp. S131. DOI: https://doi.org/10.1016/S0924-977X(16)30913-0
Details DOI

2016 | Book Chapter
Systematic Localization and Identification of SUMOylation Substrates in Knock-In Mice Expressing Affinity-Tagged SUMO1
Tirard, M.& Brose, N. (2016)
In:Rodriguez, Manuel S. (Ed.), SUMO. Methods in Molecular Biology pp. 291-301. New York: Humana Press. DOI: https://doi.org/10.1007/978-1-4939-6358-4_20
Details DOI

2016 | Journal Article | Research Paper |
Distinct modes of endocytotic presynaptic membrane and protein uptake at the calyx of Held terminal of rats and mice
Okamoto, Y.; Lipstein, N.; Hua, Y.; Lin, K.-H.; Brose, N. ; Sakaba, T. & Midorikawa, M. (2016)
eLife, 5 art. e14643. DOI: https://doi.org/10.7554/eLife.14643
Details DOI WoS

2016 | Journal Article | Research Paper |
Complexin 3 Increases the Fidelity of Signaling in a Retinal Circuit by Regulating Exocytosis at Ribbon Synapses
Mortensen, L. S.; Park, S. J.; Ke, J.-b.; Cooper, B. H. ; Zhang, L.; Imig, C. & Löwel, S. et al. (2016)
Cell Reports, 15(10) pp. 2239-2250. DOI: https://doi.org/10.1016/j.celrep.2016.05.012
Details DOI PMID PMC WoS

2016 | Journal Article
Neuroligin 2 deletion alters inhibitory synapse function and anxiety-associated neuronal activation in the amygdala
Babaev, O. ; Botta, P.; Meyer, E.; Müller, C.; Ehrenreich, H. ; Brose, N. & Lüthi, A. et al. (2016)
Neuropharmacology, 100 pp. 56-65. DOI: https://doi.org/10.1016/j.neuropharm.2015.06.016
Details DOI PMID PMC

2016 | Journal Article | Research Paper
Specificity of Collybistin-Phosphoinositide Interactions: Impact of the individual Protein Domains
Ludolphs, M. ; Schneeberger, D.; Soykan, T. ; Schäfer, J. ; Papadopoulos, T. ; Brose, N. & Schindelin, H. et al. (2016)
Journal of biological chemistry, 291(1) pp. 244-254. DOI: https://doi.org/10.1074/jbc.M115.673400
Details DOI PMID PMC WoS

2016 | Journal Article | Research Paper
Photoswitchable diacylglycerols enable optical control of protein kinase C
Frank, J. A.; Yushchenko, D. A.; Hodson, D. J.; Lipstein, N.; Nagpal, J.; Rutter, G. A. & Rhee, J.-S. et al. (2016)
Nature Chemical Biology, 12 pp. 755-762. DOI: https://doi.org/10.1038/nchembio.2141
Details DOI PMID PMC WoS

2016 | Journal Article | Research Paper |
Cognitive Deficits in Calsyntenin-2-deficient Mice Associated with Reduced GABAergic Transmission
Lipina, T. V; Prasad, T.; Yokomaku, D.; Luo, L.; Connor, S. A; Kawabe, H. & Wang, Y. T. et al. (2016)
Neuropsychopharmacology, 41 pp. 802-810. DOI: https://doi.org/10.1038/npp.2015.206
Details DOI PMID PMC WoS

2016 | Journal Article | Research Paper
Functional Roles of Complexin 3 and Complexin 4 at Mouse Photoreceptor Ribbon Synapses
Babai, N.; Sendelbeck, A.; Regus-Leidig, H.; Fuchs, M.; Mertins, J.; Reim, K. & Brose, N. et al. (2016)
The Journal of neuroscience, 36(25) pp. 6651-6667. DOI: https://doi.org/10.1523/JNEUROSCI.4335-15.2016
Details DOI PMID PMC WoS

2015 | Journal Article
Selective expression of a constitutively active erythropoietin receptor in GABAergic neurons alters hippocampal network properties without affecting cognition
Wüstefeld, L.; Winkler, D.; Janc, O. A. ; Hassouna, I. ; Ronnenberg, A.; Ostmeier, K. & Müller, M. et al. (2015)
Journal of Neurochemistry, 136(4) pp. 698-705. DOI: https://doi.org/10.1111/jnc.13445
Details DOI

2015 | Journal Article
Mammalian Unc-13 homologues as possible regulators of neurotransmitter release
Betz, A. ; Telemenakis, I. ; Hofmann, K. & Brose, N. (2015)
Biochemical Society transactions, 24(3) pp. 661-666. DOI: https://doi.org/10.1042/bst0240661
Details DOI

2015 | Journal Article
Lipid Binding Defects and Perturbed Synaptogenic Activity of a Collybistin R290H Mutant That Causes Epilepsy and Intellectual Disability
Papadopoulos, T. ; Schemm, R.; Grubmüller, H. & Brose, N. (2015)
Journal of Biological Chemistry, 290(13) pp. 8256-8270. DOI: https://doi.org/10.1074/jbc.M114.633024
Details DOI

2015 | Journal Article | Erratum
Correction: Additive effects on the energy barrier for synaptic vesicle fusion cause supralinear effects on the vesicle fusion rate
Schotten, S.; Meijer, M.; Walter, A. M.; Huson, V.; Mamer, L.; Kalogreades, L. & Veer, M. ter et al. (2015)
eLife, 4 art. e09036. DOI: https://doi.org/10.7554/elife.09036
Details DOI

2015 | Book Chapter
Pathophysiological Toolkit: Genes to Circuits
Dölen, G.; Malenka, R. C.; Perlmutter, J. S.; Brose, N. ; Frackowiak, R.; Cuthbert, B. N.& Diester, I. et al. (2015)
In:Nikolich, Karoly; Hyman, Steven E. (Eds.), Translational Neuroscience Toward New Therapies pp. 139-163. Cambridge, London: MIT Press.
Details

2015 | Journal Article |
Fast Cerebellar Reflex Circuitry Requires Synaptic Vesicle Priming by Munc13-3
Netrakanti, P. R.; Cooper, B. H. ; Dere, E. ; Poggi, G.; Winkler, D.; Brose, N. & Ehrenreich, H. (2015)
The Cerebellum, 14(3) pp. 264-283. DOI: https://doi.org/10.1007/s12311-015-0645-0
Details DOI

2015 | Journal Article | Research Paper |
Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis
Man, K. N. M ; Imig, C.; Walter, A. M; Pinheiro, P. S; Stevens, D. R; Rettig, J. & Sørensen, J. B et al. (2015)
eLife, 4 art. e10635. DOI: https://doi.org/10.7554/eLife.10635
Details DOI WoS

2015 | Journal Article | Research Paper
Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells
Vogl, C. ; Cooper, B. H. ; Neef, J. ; Wojcik, S. M. ; Reim, K.; Reisinger, E. & Brose, N. et al. (2015)
Journal of Cell Science, 128(4) pp. 638-644. DOI: https://doi.org/10.1242/jcs.162099
Details DOI PMID PMC WoS

2015 | Journal Article | Research Paper
Additive effects on the energy barrier for synaptic vesicle fusion cause supralinear effects on the vesicle fusion rate
Schotten, S.; Meijer, M.; Walter, A. M.; Huson, V.; Mamer, L.; Kalogreades, L. & Veer, M. ter et al. (2015)
eLife, 4 art. e05531. DOI: https://doi.org/10.7554/eLife.05531
Details DOI PMID PMC WoS

2015 | Journal Article | Research Paper
Complexin Stabilizes Newly Primed Synaptic Vesicles and Prevents Their Premature Fusion at the Mouse Calyx of Held Synapse
Chang, S.; Reim, K.; Pedersen, M.; Neher, E. ; Brose, N. & Taschenberger, H. (2015)
The Journal of neuroscience, 35(21) pp. 8272-8290. DOI: https://doi.org/10.1523/JNEUROSCI.4841-14.2015
Details DOI PMID PMC WoS

2015 | Journal Article
Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism
Hammer, M.; Krueger-Burg, D. ; Tuffy, L. P. ; Cooper, B. H. ; Taschenberger, H.; Goswami, S. P. & Ehrenreich, H. et al. (2015)
Cell Reports, 13(3) pp. 516-523. DOI: https://doi.org/10.1016/j.celrep.2015.09.011
Details DOI PMID PMC

2015 | Journal Article | Research Paper
Neuroligin-1 regulates excitatory synaptic transmission, LTP and EPSP-spike coupling in the dentate gyrus in vivo
Jedlicka, P.; Vnencak, M.; Krueger, D. D. ; Jungenitz, T.; Brose, N. & Schwarzacher, S. W. (2015)
Brain Structure and Function, 220(1) pp. 47-58. DOI: https://doi.org/10.1007/s00429-013-0636-1
Details DOI PMID PMC WoS

2014 | Journal Article
Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism
Ju, A.; Hammerschmidt, K. ; Tantra, M. ; Krueger, D. ; Brose, N. & Ehrenreich, H. (2014)
Behavioural Brain Research, 270 pp. 159-164. DOI: https://doi.org/10.1016/j.bbr.2014.05.019
Details DOI

2014 | Journal Article | Erratum
The Morphological and Molecular Nature of Synaptic Vesicle Priming at Presynaptic Active Zones
Imig, C.; Min, S.-W.; Krinner, S.; Arancillo, M.; Rosenmund, C.; Südhof, T. & Rhee, J. et al. (2014)
Neuron, 84(4) pp. 882. DOI: https://doi.org/10.1016/j.neuron.2014.11.003
Details DOI

2014 | Journal Article | Research Paper
Secretory Vesicle Priming by CAPS Is Independent of Its SNARE-Binding MUN Domain
Truong, C. Q. N.; Nestvogel, D.; Ratai, O.; Schirra, C.; Stevens, D. R.; Brose, N. & Rhee, J. et al. (2014)
Cell Reports, 9(3) pp. 902-909. DOI: https://doi.org/10.1016/j.celrep.2014.09.050
Details DOI WoS

2014 | Review
Neurobiology of autism gene products: towards pathogenesis and drug targets
Kleijer, K. T. E.; Schmeisser, M. J.; Krueger, D. D. ; Boeckers, T. M.; Scheiffele, P.; Bourgeron, T.& Brose, N. et al. (2014)
Psychopharmacology, 231(6) pp. 1037-1062.
Springer. DOI: https://doi.org/10.1007/s00213-013-3403-3
Details DOI PMID PMC WoS

2014 | Journal Article | Research Paper
Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting
Biesemann, C.; Grønborg, M.; Luquet, E.; Wichert, S. P; Bernard, V.; Bungers, S. R & Cooper, B. et al. (2014)
EMBO Journal, 33(2) pp. 157-170. DOI: https://doi.org/10.1002/embj.201386120
Details DOI PMID PMC WoS

2014 | Journal Article | Letter Note
All Roads Lead to Neuroscience: The 2013 Nobel Prize in Physiology or Medicine
Brose, N. (2014)
Neuron, 81(4) pp. 723-727. DOI: https://doi.org/10.1016/j.neuron.2014.02.008
Details DOI PMID PMC WoS

2014 | Journal Article | Research Paper
A conformational switch in collybistin determines the differentiation of inhibitory postsynapses
Soykan, T. ; Schneeberger, D.; Tria, G.; Buechner, C.; Bader, N.; Svergun, D. & Tessmer, I. et al. (2014)
EMBO Journal, 33(18) pp. 2113-2133. DOI: https://doi.org/10.15252/embj.201488143
Details DOI PMID PMC WoS

2014 | Journal Article | Research Paper
The Morphological and Molecular Nature of Synaptic Vesicle Priming at Presynaptic Active Zones
Imig, C.; Min, S.-W.; Krinner, S. ; Arancillo, M.; Rosenmund, C.; Südhof, T. C. & Rhee, J. et al. (2014)
Neuron, 84(2) pp. 416-431. DOI: https://doi.org/10.1016/j.neuron.2014.10.009
Details DOI PMID PMC WoS

2014 | Journal Article | Research Paper
Complexin synchronizes primed vesicle exocytosis and regulates fusion pore dynamics
Dhara, M.; Yarzagaray, A.; Schwarz, Y.; Dutta, S.; Grabner, C. ; Moghadam, P. K. & Bost, A. et al. (2014)
The Journal of Cell Biology, 204(7) pp. 1123-1140. DOI: https://doi.org/10.1083/jcb.201311085
Details DOI PMID PMC WoS

2014 | Journal Article | Research Paper
Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth
Hsia, H.-E.; Kumar, R.; Luca, R.; Takeda, M.; Courchet, J.; Nakashima, J. & Wu, S. et al. (2014)
Proceedings of the National Academy of Sciences, 111(36) pp. 13205-13210. DOI: https://doi.org/10.1073/pnas.1400737111
Details DOI PMID PMC WoS

2014 | Journal Article | Research Paper
Munc13-3 Superprimes Synaptic Vesicles at Granule Cell-to-Basket Cell Synapses in the Mouse Cerebellum
Ishiyama, S.; Schmidt, H.; Cooper, B. H. ; Brose, N. & Eilers, J. (2014)
The Journal of neuroscience, 34(44) pp. 14687-14696. DOI: https://doi.org/10.1523/JNEUROSCI.2060-14.2014
Details DOI PMID PMC WoS

2013 | Journal Article
Nobel 2013 Physiology or medicine: Traffic control system within cells
Ferro-Novick, S. & Brose, N. (2013)
Nature, 504(7478). DOI: https://doi.org/10.1038/504098a
Details DOI

2013 | Conference Abstract
Lipid binding characteristics of collybistin
Schatz, M.; Soykan, T.; Brose, N. & Steinem, C. (2013)
European Biophysics Journal, 42 , Lisbon, Portugal.
New york: Springer.
Details WoS

2013 | Journal Article |
Genetic Markers of a Munc13 Protein Family Member, BAIAP3, Are Gender Specifically Associated with Anxiety and Benzodiazepine Abuse in Mice and Humans
Wojcik, S. M. ; Tantra, M. ; Stepniak, B. ; Man, K. Man, Kwun-nok M ; Müller-Ribbe, K.; Begemann, M. & Ju, A. et al. (2013)
Molecular Medicine, 19 pp. 135-148. DOI: https://doi.org/10.2119/molmed.2013.00033
Details DOI PMID PMC

2013 | Journal Article | Research Paper
The Specific α-Neurexin Interactor Calsyntenin-3 Promotes Excitatory and Inhibitory Synapse Development
Pettem, K. L.; Yokomaku, D.; Luo, L.; Linhoff, M. W.; Prasad, T.; Connor, S. A. & Siddiqui, T. J. et al. (2013)
Neuron, 80(1) pp. 113-128. DOI: https://doi.org/10.1016/j.neuron.2013.07.016
Details DOI PMID PMC WoS

2013 | Journal Article | Research Paper
Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism
El-Kordi, A. ; Winkler, D.; Hammerschmidt, K. ; Kästner, A. ; Krueger, D. ; Ronnenberg, A. & Ritter, C. et al. (2013)
Behavioural Brain Research, 251 pp. 41-49. DOI: https://doi.org/10.1016/j.bbr.2012.11.016
Details DOI PMID PMC WoS

2013 | Journal Article | Research Paper
Collybistin activation by GTP-TC10 enhances postsynaptic gephyrin clustering and hippocampal GABAergic neurotransmission
Mayer, S.; Kumar, R.; Jaiswal, M.; Soykan, T. ; Ahmadian, M. R.; Brose, N. & Betz, H. et al. (2013)
Proceedings of the National Academy of Sciences, 110(51) pp. 20795-20800. DOI: https://doi.org/10.1073/pnas.1309078110
Details DOI PMID PMC WoS

2013 | Journal Article | Research Paper
Neurobeachin regulates neurotransmitter receptor trafficking to synapses
Nair, R.; Lauks, J.; Jung, S. ; Cooke, N. E.; de Wit, H.; Brose, N. & Kilimann, M. W. et al. (2013)
The Journal of Cell Biology, 200(1) pp. 61-80. DOI: https://doi.org/10.1083/jcb.201207113
Details DOI PMID PMC WoS

2013 | Journal Article | Research Paper
Spike bursts increase amyloid-β 40/42 ratio by inducing a presenilin-1 conformational change
Dolev, I.; Fogel, H.; Milshtein, H.; Berdichevsky, Y.; Lipstein, N.; Brose, N. & Gazit, N. et al. (2013)
Nature Neuroscience, 16(5) pp. 587-595. DOI: https://doi.org/10.1038/nn.3376
Details DOI PMID PMC WoS

2013 | Journal Article | Letter Note
Why we need more synaptogenic cell-adhesion proteins
Brose, N. (2013)
Proceedings of the National Academy of Sciences, 110(10) pp. 3717-3718. DOI: https://doi.org/10.1073/pnas.1300505110
Details DOI PMID PMC WoS

2013 | Journal Article | Research Paper
Dynamic Control of Synaptic Vesicle Replenishment and Short-Term Plasticity by Ca²⁺-Calmodulin-Munc13-1 Signaling
Lipstein, N.; Sakaba, T.; Cooper, B. H. ; Lin, K.-H.; Strenzke, N. ; Ashery, U. & Rhee, J.-S. et al. (2013)
Neuron, 79(1) pp. 82-96. DOI: https://doi.org/10.1016/j.neuron.2013.05.011
Details DOI PMID PMC WoS

2013 | Journal Article | Letter Note
Evidence for a Common Endocannabinoid-Related Pathomechanism in Autism Spectrum Disorders
Krueger, D. D. & Brose, N. (2013)
Neuron, 78(3) pp. 408-410. DOI: https://doi.org/10.1016/j.neuron.2013.04.030
Details DOI PMID PMC WoS

2013 | Journal Article | Research Paper
An LRRTM4-HSPG Complex Mediates Excitatory Synapse Development on Dentate Gyrus Granule Cells
Siddiqui, T. J.; Tari, P. K.; Connor, S. A.; Zhang, P.; Dobie, F. A.; She, K. & Kawabe, H. et al. (2013)
Neuron, 79(4) pp. 680-695. DOI: https://doi.org/10.1016/j.neuron.2013.06.029
Details DOI PMID PMC WoS

2012 | Review
Structural plasticity of spines at giant mossy fiber synapses
Zhao, S.; Studer, D.; Chai, X.; Graber, W.; Brose, N. ; Nestel, S.& Young, C. et al. (2012)
Frontiers in Neural Circuits, 6.
Frontiers Research Foundation. DOI: https://doi.org/10.3389/fncir.2012.00103
Details DOI PMID PMC WoS

2012 | Journal Article
SNARE Protein Recycling by αSNAP and βSNAP Supports Synaptic Vesicle Priming
Burgalossi, A.; Jung, S.; Meyer, G.; Jockusch, W.; Jahn, O.; Taschenberger, H. & O'Connor, V. et al. (2012)
Neuron, 73(3) pp. 620. DOI: https://doi.org/10.1016/j.neuron.2012.01.015
Details DOI

2012 | Journal Article | Research Paper
The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses
Krueger, D. D. ; Tuffy, L. P. ; Papadopoulos, T. & Brose, N. (2012)
Current Opinion in Neurobiology, 22(3) pp. 412-422. DOI: https://doi.org/10.1016/j.conb.2012.02.012
Details DOI PMID PMC WoS

2012 | Journal Article | Research Paper
CaMKII binding to GluN2B is critical during memory consolidation
Halt, A. R; Dallapiazza, R. F; Zhou, Y.; Stein, I. S; Qian, H.; Juntti, S. & Wojcik, S. et al. (2012)
EMBO Journal, 31(5) pp. 1203-1216. DOI: https://doi.org/10.1038/emboj.2011.482
Details DOI PMID PMC WoS

2012 | Journal Article | Research Paper
Homodimerization and isoform-specific heterodimerization of neuroligins
Poulopoulos, A.; Soykan, T. ; Tuffy, L. P. ; Hammer, M.; Varoqueaux, F. & Brose, N. (2012)
Biochemical Journal, 446(2) pp. 321-330. DOI: https://doi.org/10.1042/BJ20120808
Details DOI PMID PMC WoS

2012 | Journal Article | Research Paper
Structural plasticity of hippocampal mossy fiber synapses as revealed by high-pressure freezing
Zhao, S.; Studer, D.; Chai, X.; Graber, W.; Brose, N. ; Nestel, S. & Young, C. et al. (2012)
The Journal of Comparative Neurology, 520(11) pp. 2340-2351. DOI: https://doi.org/10.1002/cne.23040
Details DOI PMID PMC WoS

2012 | Journal Article | Research Paper
The cytoskeletal adapter protein 4.1G organizes the internodes in peripheral myelinated nerves
Ivanovic, A. ; Horresh, I.; Golan, N.; Spiegel, I.; Sabanay, H.; Frechter, S. & Ohno, S. et al. (2012)
The Journal of Cell Biology, 196(3) pp. 337-344. DOI: https://doi.org/10.1083/jcb.201111127
Details DOI PMID PMC WoS

2012 | Journal Article | Research Paper
In vivo localization and identification of SUMOylated proteins in the brain of His(6)-HA-SUMO1 knock-in mice
Tirard, M.; Hsiao, H.-H.; Nikolov, M. ; Urlaub, H. ; Melchior, F. & Brose, N. (2012)
Proceedings of the National Academy of Sciences, 109(51) pp. 21122-21127. DOI: https://doi.org/10.1073/pnas.1215366110
Details DOI PMID PMC WoS

2012 | Journal Article | Research Paper
Munc13-Independent Vesicle Priming at Mouse Photoreceptor Ribbon Synapses
Cooper, B. ; Hemmerlein, M.; Ammermüller, J.; Imig, C.; Reim, K.; Lipstein, N. & Kalla, S. et al. (2012)
The Journal of Neuroscience, 32(23) pp. 8040-8052. DOI: https://doi.org/10.1523/JNEUROSCI.4240-11.2012
Details DOI PMID PMC WoS

2012 | Journal Article | Research Paper
Nonconserved Ca²⁺/Calmodulin Binding Sites in Munc13s Differentially Control Synaptic Short-Term Plasticity
Lipstein, N.; Schaks, S.; Dimova, K.; Kalkhof, S.; Ihling, C.; Kölbel, K. & Ashery, U. et al. (2012)
Molecular and Cellular Biology, 32(22) pp. 4628-4641. DOI: https://doi.org/10.1128/MCB.00933-12
Details DOI PMID PMC WoS

2012 | Journal Article | Research Paper
The RacGAP β2-Chimaerin Selectively Mediates Axonal Pruning in the Hippocampus
Riccomagno, M. M.; Hurtado, A.; Wang, H.; Macopson, J. G. J.; Griner, E. M.; Betz, A. & Brose, N. et al. (2012)
Cell, 149(7) pp. 1594-1606. DOI: https://doi.org/10.1016/j.cell.2012.05.018
Details DOI PMID PMC WoS

2012 | Journal Article | Research Paper
Analysis of neurotransmitter release mechanisms by photolysis of caged Ca²⁺ in an autaptic neuron culture system
Burgalossi, A.; Jung, S. ; Man, K. Man, Kwun-nok Mimi ; Nair, R.; Jockusch, W. J; Wojcik, S. M & Brose, N. et al. (2012)
Nature Protocols, 7(7) pp. 1351-1365. DOI: https://doi.org/10.1038/nprot.2012.074
Details DOI PMID PMC WoS

2011 | Journal Article | Research Paper
Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina
Hoon, M.; Soykan, T. ; Falkenburger, B.; Hammer, M.; Patrizi, A.; Schmidt, K.-F. & Sassoè-Pognetto, M. et al. (2011)
Proceedings of the National Academy of Sciences, 108(7) pp. 3053-3058. DOI: https://doi.org/10.1073/pnas.1006946108
Details DOI PMID PMC WoS

2011 | Journal Article | Research Paper
Increased Dentate Gyrus Excitability in Neuroligin-2-Deficient Mice in Vivo
Jedlicka, P.; Hoon, M.; Papadopoulos, T. ; Vlachos, A.; Winkels, R.; Poulopoulos, A. & Betz, H. et al. (2011)
Cerebral Cortex, 21(2) pp. 357-367. DOI: https://doi.org/10.1093/cercor/bhq100
Details DOI PMID PMC WoS

2011 | Journal Article | Research Paper
Exocytosis at the hair cell ribbon synapse apparently operates without neuronal SNARE proteins
Nouvian, R. ; Neef, J. ; Bulankina, A. V; Reisinger, E. ; Pangršič, T. ; Frank, T. & Sikorra, S. et al. (2011)
Nature Neuroscience, 14(4) pp. 411-413. DOI: https://doi.org/10.1038/nn.2774
Details DOI PMID PMC WoS

2011 | Journal Article | Research Paper |
A CAG repeat polymorphism of KCNN3 predicts SK3 channel function and cognitive performance in schizophrenia
Grube, S.; Gerchen, M. F.; Adamcio, B. ; Pardo, L. A. ; Martin, S. ; Malzahn, D. & Papiol, S. et al. (2011)
EMBO Molecular Medicine, 3(6) pp. 309-319. DOI: https://doi.org/10.1002/emmm.201100135
Details DOI PMID PMC WoS

2011 | Journal Article | Research Paper
Probing the Functional Equivalence of Otoferlin and Synaptotagmin 1 in Exocytosis
Reisinger, E. ; Bresee, C.; Neef, J. ; Nair, R.; Reuter, K.; Bulankina, A. & Nouvian, R. et al. (2011)
The Journal of Neuroscience, 31(13) pp. 4886-4895. DOI: https://doi.org/10.1523/JNEUROSCI.5122-10.2011
Details DOI PMID PMC WoS

2011 | Review
The role of ubiquitylation in nerve cell development
Kawabe, H.& Brose, N. (2011)
Nature Reviews Neuroscience, 12(5) pp. 251-268.
Nature Publishing Group. DOI: https://doi.org/10.1038/nrn3009
Details DOI PMID PMC WoS

2011 | Journal Article | Research Paper
In Vivo Imaging of Intersynaptic Vesicle Exchange Using VGLUT1(Venus) Knock-In Mice
Herzog, E.; Nadrigny, F.; Silm, K.; Biesemann, C.; Helling, I.; Bersot, T. & Steffens, H. et al. (2011)
The Journal of Neuroscience, 31(43) pp. 15544-15559. DOI: https://doi.org/10.1523/JNEUROSCI.2073-11.2011
Details DOI PMID PMC WoS

2011 | Journal Article | Research Paper
Deletion of the ubiquitin ligase Nedd4L in lung epithelia causes cystic fibrosis-like disease
Kimura, T.; Kawabe, H.; Jiang, C.; Zhang, W.; Xiang, Y.-Y.; Lu, C. & Salter, M. W. et al. (2011)
Proceedings of the National Academy of Sciences, 108(8) pp. 3216-3221. DOI: https://doi.org/10.1073/pnas.1010334108
Details DOI PMID PMC WoS

2010 | Journal Article
Regulation of Rap2A by the Ubiquitin Ligase Nedd4-1 Controls Neurite Development
Kawabe, H.; Neeb, A.; Dimova, K.; Young, S.; Takeda, M.; Katsurabayashi, S. & Mitkovski, M. et al. (2010)
Neuroscience Research, 68 pp. e58. DOI: https://doi.org/10.1016/j.neures.2010.07.025
Details DOI

2010 | Conference Abstract
Complexin2 Gene Polymorphisms Modify Cognitive Performance in Schizophrenia
Klaus, S.; Begemann, M.; Papiol, S.; Malzahn, D. ; Friedrichs, H.; Ribbe, K. & El-Kordi, A. et al. (2010)
Schizophrenia Research, 117(2-3) pp. 337-338. , Florence, ITALY.
Amsterdam: Elsevier Science Bv.
Details WoS

2010 | Journal Article |
Modification of cognitive performance in schizophrenia by complexin 2 gene polymorphisms
Begemann, M. ; Grube, S.; Papiol, S. ; Malzahn, D. ; Krampe, H. ; Ribbe, K. & Friedrichs, H. et al. (2010)
Archives of General Psychiatry, 67(9) pp. 879-888. DOI: https://doi.org/10.1001/archgenpsychiatry.2010.107
Details DOI

2010 | Journal Article |
The cross-sectional GRAS sample: a comprehensive phenotypical data collection of schizophrenic patients
Ribbe, K. ; Friedrichs, H. ; Begemann, M. ; Grube, S.; Papiol, S. ; Kästner, A. & Gerchen, M. F. et al. (2010)
BMC Psychiatry, 10 art. 91. DOI: https://doi.org/10.1186/1471-244X-10-91
Details DOI

2010 | Journal Article | Research Paper
Munc13-2 Differentially Affects Hippocampal Synaptic Transmission and Plasticity
Breustedt, J.; Gundlfinger, A.; Varoqueaux, F.; Reim, K.; Brose, N. & Schmitz, D. (2010)
Cerebral Cortex, 20(5) pp. 1109-1120. DOI: https://doi.org/10.1093/cercor/bhp170
Details DOI PMID PMC WoS

2010 | Journal Article | Research Paper
Doc2b Is a High-Affinity Ca²⁺ Sensor for Spontaneous Neurotransmitter Release
Groffen, A. J.; Martens, S.; Arazola, R. D.; Cornelisse, L. N.; Lozovaya, N.; Jong, A. P. H. de & Goriounova, N. A. et al. (2010)
Science, 327(5973) pp. 1614-1618. DOI: https://doi.org/10.1126/science.1183765
Details DOI PMID PMC WoS

2010 | Journal Article | Research Paper
Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca²⁺ and possible function in short-term synaptic plasticity
Rodriguez-Castaneda, F.; Maestre-Martinez, M.; Coudevylle, N.; Dimova, K.; Junge, H. J.; Lipstein, N. & Lee, D. et al. (2010)
EMBO Journal, 29(3) pp. 680-691. DOI: https://doi.org/10.1038/emboj.2009.373
Details DOI PMID PMC WoS

2010 | Journal Article | Research Paper
Complexin2 null mutation requires a 'second hit' for induction of phenotypic changes relevant to schizophrenia
Radyushkin, K.; El-Kordi, A. ; Boretius, S. ; Castaneda, S.; Ronnenberg, A.; Reim, K. & Bickeböller, H. et al. (2010)
Genes, Brain and Behavior, 9(6) pp. 592-602. DOI: https://doi.org/10.1111/j.1601-183X.2010.00590.x
Details DOI PMID PMC WoS

2010 | Journal Article | Research Paper
The Ubiquitin Ligase Nedd4-1 Is Required for Heart Development and Is a Suppressor of Thrombospondin-1
Fouladkou, F.; Lu, C.; Jiang, C.; Zhou, L.; She, Y.; Walls, J. R. & Kawabe, H. et al. (2010)
Journal of biological chemistry, 285(9) pp. 6770-6780. DOI: https://doi.org/10.1074/jbc.M109.082347
Details DOI PMID PMC WoS

2010 | Journal Article | Letter Note
The ubiquitin E3 ligase Nedd4-1 controls neurite development
Kawabe, H. & Brose, N. (2010)
Cell Cycle, 9(13) pp. 2477-2478. DOI: https://doi.org/10.4161/cc.9.13.12236
Details DOI PMID PMC WoS

2010 | Journal Article | Research Paper |
¹H, ¹³C and ¹⁵N resonance assignments of the Calmodulin-Munc13-1 peptide complex
Rodriguez-Castaneda, F.; Coudevylle, N.; Becker, S. ; Brose, N. ; Carlomagno, T. & Griesinger, C. (2010)
Biomolecular NMR Assignments, 4(1) pp. 45-48. DOI: https://doi.org/10.1007/s12104-009-9204-2
Details DOI PMID PMC WoS

2010 | Journal Article | Research Paper
SNARE Protein Recycling by alpha SNAP and beta SNAP Supports Synaptic Vesicle Priming
Burgalossi, A.; Jung, S. ; Meyer, G.; Jockusch, W. J.; Jahn, O. ; Taschenberger, H. & O'Connor, V. M. et al. (2010)
Neuron, 68(3) pp. 473-487. DOI: https://doi.org/10.1016/j.neuron.2010.09.019
Details DOI PMID PMC WoS

2010 | Journal Article | Research Paper
Regulation of Rap2A by the Ubiquitin Ligase Nedd4-1 Controls Neurite Development
Kawabe, H.; Neeb, A.; Dimova, K.; Young, S. M. J.; Takeda, M.; Katsurabayashi, S. & Mitkovski, M. et al. (2010)
Neuron, 65(3) pp. 358-372. DOI: https://doi.org/10.1016/j.neuron.2010.01.007
Details DOI PMID PMC WoS

2010 | Journal Article | Research Paper
Munc13 C2B domain is an activity-dependent Ca²⁺ regulator of synaptic exocytosis
Shin, O.-H.; Lu, J.; Rhee, J.-S. ; Tomchick, D. R.; Pang, Z. P.; Wojcik, S. M. & Camacho-Perez, M. et al. (2010)
Nature Structural & Molecular Biology, 17(3) pp. 280-U42. DOI: https://doi.org/10.1038/nsmb.1758
Details DOI PMID PMC WoS

2010 | Journal Article | Research Paper
Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells
Pangršič, T. ; Lasarow, L.; Reuter, K.; Takago, H.; Schwander, M.; Riedel, D. & Frank, T. et al. (2010)
Nature Neuroscience, 13(7) pp. 869-U116. DOI: https://doi.org/10.1038/nn.2578
Details DOI PMID PMC WoS

2010 | Conference Paper | Research Paper
Synaptopathy: dysfunction of synaptic function?
Brose, N. ; O'Connor, V. & Skehel, P. (2010)
Biochemical Society transactions pp. 443-444. (Vol. 38). Conference on Synaptopathies - Dysfunction of Synaptic Function, Newquay, ENGLAND.
London: Portland Press Ltd. DOI: https://doi.org/10.1042/BST0380443
Details DOI PMID PMC WoS

2010 | Journal Article | Research Paper
Two distinct secretory vesicle-priming steps in adrenal chromaffin cells
Liu, Y.; Schirra, C.; Edelmann, L.; Matti, U.; Rhee, J.-S. ; Hof, D. & Bruns, D. et al. (2010)
The Journal of Cell Biology, 190(6) pp. 1067-1077. DOI: https://doi.org/10.1083/jcb.201001164
Details DOI PMID PMC WoS

2009 | Journal Article
The function of glutamatergic synapses is not perturbed by severe knockdown of 4.1N and 4.1G expression
Wozny, C.; Breustedt, J.; Wolk, F. ; Varoqueaux, F.; Boretius, S. ; Zivkovic, A. R. & Neeb, A. et al. (2009)
Journal of Cell Science, 122(5) pp. 735-744. DOI: https://doi.org/10.1242/jcs.037382
Details DOI

2009 | Journal Article | Research Paper
Neuroligin 2 Drives Postsynaptic Assembly at Perisomatic Inhibitory Synapses through Gephyrin and Collybistin
Poulopoulos, A.; Aramuni, G.; Meyer, G.; Soykan, T. ; Hoon, M.; Papadopoulos, T. & Zhang, M. et al. (2009)
Neuron, 63(5) pp. 628-642. DOI: https://doi.org/10.1016/j.neuron.2009.08.023
Details DOI PMID PMC WoS

2009 | Journal Article | Research Paper
Structural Insights into the Calmodulin-Munc13 Interaction Obtained by Cross-Linking and Mass Spectrometry
Dimova, K.; Kalkhof, S.; Pottratz, I.; Ihling, C.; Rodriguez-Castaneda, F.; Liepold, T. & Griesinger, C. et al. (2009)
Biochemistry, 48(25) pp. 5908-5921. DOI: https://doi.org/10.1021/bi900300r
Details DOI PMID PMC WoS

2009 | Journal Article
Neuroligin-3-deficient mice: model of a monogenic heritable form of autism with an olfactory deficit
Radyushkin, K.; Hammerschmidt, K. ; Boretius, S. ; Varoqueaux, F.; El-Kordi, A. ; Ronnenberg, A. & Winter, D. et al. (2009)
Genes, Brain and Behavior, 8(4) pp. 416-425. DOI: https://doi.org/10.1111/j.1601-183x.2009.00487.x
Details DOI PMID PMC

2009 | Journal Article | Research Paper
Synaptic PRG-1 Modulates Excitatory Transmission via Lipid Phosphate-Mediated Signaling
Trimbuch, T.; Beed, P.; Vogt, J.; Schuchmann, S.; Maier, N.; Kintscher, M. & Breustedt, J. et al. (2009)
Cell, 138(6) pp. 1222-1235. DOI: https://doi.org/10.1016/j.cell.2009.06.050
Details DOI PMID PMC WoS

2009 | Journal Article | Research Paper
A common molecular basis for membrane docking and functional priming of synaptic vesicles
Siksou, L.; Varoqueaux, F.; Pascual, O.; Triller, A.; Brose, N. & Marty, S. (2009)
European Journal of Neuroscience, 30(1) pp. 49-56. DOI: https://doi.org/10.1111/j.1460-9568.2009.06811.x
Details DOI PMID PMC WoS

2009 | Journal Article | Research Paper
A chloride conductance in VGLUT1 underlies maximal glutamate loading into synaptic vesicles
Schenck, S.; Wojcik, S. M. ; Brose, N. & Takamori, S. (2009)
Nature Neuroscience, 12(2) pp. 156-162. DOI: https://doi.org/10.1038/nn.2248
Details DOI PMID PMC WoS

2009 | Journal Article | Letter Note
Synaptogenic Proteins and Synaptic Organizers: “Many Hands Make Light Work”
Brose, N. (2009)
Neuron, 61(5) pp. 650-652. DOI: https://doi.org/10.1016/j.neuron.2009.02.014
Details DOI PMID PMC WoS

2009 | Journal Article | Research Paper
Postsynaptic Neuroligin1 regulates presynaptic maturation
Wittenmayer, N.; Koerber, C.; Liu, H.; Kremer, T.; Varoqueaux, F.; Chapman, E. R. & Brose, N. et al. (2009)
Proceedings of the National Academy of Sciences, 106(32) pp. 13564-13569. DOI: https://doi.org/10.1073/pnas.0905819106
Details DOI PMID PMC WoS

2009 | Journal Article | Research Paper
Ca²⁺-dependent Activator Proteins of Secretion Promote Vesicular Monoamine Uptake
Brunk, I.; Blex, C.; Speidel, D.; Brose, N. & Ahnert-Hilger, G. (2009)
Journal of biological chemistry, 284(2) pp. 1050-1056. DOI: https://doi.org/10.1074/jbc.M805328200
Details DOI PMID PMC WoS

2009 | Journal Article | Research Paper
Complexin-I Is Required for High-Fidelity Transmission at the Endbulb of Held Auditory Synapse
Strenzke, N. ; Chanda, S.; Kopp-Scheinpflug, C.; Khimich, D. ; Reim, K.; Bulankina, A. V. & Neef, A. et al. (2009)
The Journal of neuroscience, 29(25) pp. 7991-8004. DOI: https://doi.org/10.1523/JNEUROSCI.0632-09.2009
Details DOI PMID PMC WoS

2009 | Journal Article | Research Paper
Increased anxiety-like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2
Blundell, J.; Tabuchi, K.; Bolliger, M. F.; Blaiss, C. A.; Brose, N. ; Liu, X. & Suedhof, T. C. et al. (2009)
Genes, Brain and Behavior, 8(1) pp. 114-126. DOI: https://doi.org/10.1111/j.1601-183X.2008.00455.x
Details DOI PMID PMC WoS

2009 | Journal Article | Letter Note
Flowers for Synaptic Endocytosis
Brose, N. & Neher, E. (2009)
Cell, 138(5) pp. 836-837. DOI: https://doi.org/10.1016/j.cell.2009.08.023
Details DOI PMID PMC WoS

2009 | Journal Article | Research Paper
Aberrant function and structure of retinal ribbon synapses in the absence of complexin 3 and complexin 4
Reim, K.; Regus-Leidig, H.; Ammermueller, J.; El-Kordi, A. ; Radyushkin, K.; Ehrenreich, H. & Brandstaetter, J. H. et al. (2009)
Journal of Cell Science, 122(9) pp. 1352-1361. DOI: https://doi.org/10.1242/jcs.045401
Details DOI PMID PMC WoS

2008 | Journal Article
Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism
Jamain, S.; Radyushkin, K.; Hammerschmidt, K. ; Granon, S.; Boretius, S. ; Varoqueaux, F. & Ramanantsoa, N. et al. (2008)
Proceedings of the National Academy of Sciences of the United States of America, 105(5) pp. 1710-1715. DOI: https://doi.org/10.1073/pnas.0711555105
Details DOI

2008 | Review
Altered Complexin expression in psychiatric and neurological disorders: Cause or consequence?
Brose, N. (2008)
Molecules and Cells, 25(1) pp. 7-19.
Korean Soc Molecular & Cellular Biology.
Details PMID PMC WoS

2008 | Journal Article | Research Paper
Complexin II plays a positive role in Ca²⁺-triggered exocytosis by facilitating vesicle priming
Cai, H.; Reim, K.; Varoqueaux, F.; Tapechum, S.; Hill, K.; Sørensen, J. B. & Brose, N. et al. (2008)
Proceedings of the National Academy of Sciences, 105(49) pp. 19538-19543. DOI: https://doi.org/10.1073/pnas.0810232105
Details DOI PMID PMC WoS

2008 | Journal Article | Research Paper |
Erythropoietin enhances hippocampal long-term potentiation and memory
Adamcio, B. ; Sargin, D. ; Stradomska, A. ; Medrihan, L. ; Gertler, C.; Theis, F. & Zhang, M. et al. (2008)
BMC Biology, 6 art. 37. DOI: https://doi.org/10.1186/1741-7007-6-37
Details DOI PMID PMC WoS

2008 | Journal Article | Research Paper
CAPS1 and CAPS2 regulate stability and recruitment of insulin granules in mouse pancreatic beta cells
Speidel, D.; Salehi, A.; Obermueller, S.; Lundquist, I.; Brose, N. ; Renstroem, E. & Rorsman, P. (2008)
Cell Metabolism, 7(1) pp. 57-67. DOI: https://doi.org/10.1016/j.cmet.2007.11.009
Details DOI PMID PMC WoS

2008 | Journal Article | Research Paper
Phorbol esters modulate spontaneous and Ca²⁺-evoked transmitter release via acting on both munc13 and protein kinase C
Lou, X.; Korogod, N.; Brose, N. & Schneggenburger, R. (2008)
The Journal of neuroscience, 28(33) pp. 8257-8267. DOI: https://doi.org/10.1523/JNEUROSCI.0550-08.2008
Details DOI PMID PMC WoS

2008 | Journal Article | Research Paper
The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization
Fouladkou, F.; Landry, T.; Kawabe, H.; Neeb, A.; Lu, C.; Brose, N. & Stambolic, V. et al. (2008)
Proceedings of the National Academy of Sciences, 105(25) pp. 8585-8590. DOI: https://doi.org/10.1073/pnas.0803233105
Details DOI PMID PMC WoS

2008 | Journal Article | Research Paper
Vesicle priming and recruitment by ubMunc13-2 are differentially regulated by calcium and calmodulin
Zikich, D.; Mezer, A.; Varoqueaux, F.; Sheinin, A.; Junge, H. J.; Nachliel, E. & Melamed, R. et al. (2008)
The Journal of neuroscience, 28(8) pp. 1949-1960. DOI: https://doi.org/10.1523/JNEUROSCI.5096-07.2008
Details DOI PMID PMC WoS

2008 | Review
For better or for worse: Complexins regulate SNARE function and vesicle fusion
Brose, N. (2008)
Traffic, 9(9) pp. 1403-1413.
Wiley-blackwell. DOI: https://doi.org/10.1111/j.1600-0854.2008.00758.x
Details DOI PMID PMC WoS

2008 | Journal Article | Research Paper
CAPS facilitates filling of the rapidly releasable pool of large dense-core vesicles
Liu, Y.; Schirra, C.; Stevens, D. R.; Matti, U.; Speidel, D.; Hof, D. & Bruns, D. et al. (2008)
The Journal of neuroscience, 28(21) pp. 5594-5601. DOI: https://doi.org/10.1523/JNEUROSCI.5672-07.2008
Details DOI PMID PMC WoS

2008 | Journal Article
Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system
Xue, M.; Stradomska, A. ; Chen, H.; Brose, N. ; Zhang, W. ; Rosenmund, C. & Reim, K. (2008)
Proceedings of the National Academy of Sciences, 105(22) pp. 7875-7880. DOI: https://doi.org/10.1073/pnas.0803012105
Details DOI PMID PMC WoS

2008 | Journal Article | Research Paper
Synapse formation and clustering of neuroligin-2 in the absence of GABA(A) receptors
Patrizi, A.; Scelfo, B.; Viltono, L.; Briatore, F.; Fukaya, M.; Watanabe, M. & Strata, P. et al. (2008)
Proceedings of the National Academy of Sciences, 105(35) pp. 13151-13156. DOI: https://doi.org/10.1073/pnas.0802390105
Details DOI PMID PMC WoS

2007 | Journal Article
Regulation of dendritic development by E3 ubiquitin ligase Nedd4
Kawabe, H.; Rhee, J.-S.; Katsurabayashi, S.; Neeb, A.; Umikawa, M.; Kariya, K.-i. & Rosenmund, C. et al. (2007)
Neuroscience Research, 58 pp. S39. DOI: https://doi.org/10.1016/j.neures.2007.06.228
Details DOI

2007 | Journal Article
Autismus - Wenn Nervenzellen kontaktscheu sind
Brose, N. (2007)
Biospektrum, 13(6) pp. 614-616.
Details

2007 | Journal Article | Research Paper
EphA4-Dependent axon guidance is mediated by the RacGAP alpha 2-chirnaerin
Wegmeyer, H.; Egea, J.; Rabe, N.; Gezelius, H.; Filosa, A.; Enjin, A. & Varoqueaux, F. et al. (2007)
Neuron, 55(5) pp. 756-767. DOI: https://doi.org/10.1016/j.neuron.2007.07.038
Details DOI PMID PMC WoS

2007 | Journal Article | Research Paper
CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins
Jockusch, W. J.; Speidel, D.; Sigler, A.; Sørensen, J. B.; Varoqueaux, F.; Rhee, J.-S. & Brose, N. (2007)
Cell, 131(4) pp. 796-808. DOI: https://doi.org/10.1016/j.cell.2007.11.002
Details DOI PMID PMC WoS

2007 | Journal Article | Research Paper
Distinct domains of complexin I differentially regulate neurotransmitter release
Xue, M.; Reim, K.; Chen, X.; Chao, H.-T.; Deng, H.; Rizo, J. & Brose, N. et al. (2007)
Nature Structural & Molecular Biology, 14(10) pp. 949-958. DOI: https://doi.org/10.1038/nsmb1292
Details DOI PMID PMC WoS

2007 | Journal Article | Research Paper
Enhanced anxiety, depressive-like behaviour and impaired recognition memory in mice with reduced expression of the vesicular glutamate transporter 1 (VGLUT1)
Tordera, R. M.; Totterdell, S.; Wojcik, S. M. ; Brose, N. ; Elizalde, N.; Lasheras, B. & Rio, J. del (2007)
European Journal of Neuroscience, 25(1) pp. 281-290. DOI: https://doi.org/10.1111/j.1460-9568.2006.05259.x
Details DOI PMID PMC WoS

2007 | Review
Regulation of membrane fusion in synaptic excitation-secretion coupling: Speed and accuracy matter
Wojcik, S. M. & Brose, N. (2007)
Neuron, 55(1) pp. 11-24.
Cell Press. DOI: https://doi.org/10.1016/j.neuron.2007.06.013
Details DOI PMID PMC WoS

2007 | Journal Article | Research Paper
Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion
Basu, J.; Betz, A. ; Brose, N. & Rosenmund, C. (2007)
The Journal of neuroscience, 27(5) pp. 1200-1210. DOI: https://doi.org/10.1523/JNEUROSCI.4908-06.2007
Details DOI PMID PMC WoS

2007 | Conference Paper | Research Paper
Depletion of Complexin II does not affect disease progression in a mouse model of Huntington's disease (HD); support for role for complexin II in behavioural pathology in a mouse model of HD
Glynn, D.; Reim, K.; Brose, N. & Morton, J. A. (2007)
Brain Research Bulletin (2-3) pp. 108-120. (Vol. 72). Second World Congress on Huntington's Disease, Manchester, England.
Oxford: Elsevier. DOI: https://doi.org/10.1016/j.brainresbull.2006.10.017
Details DOI PMID PMC WoS

2007 | Journal Article | Research Paper
Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2
Chubykin, A. A.; Atasoy, D.; Etherton, M. R.; Brose, N. ; Kavalali, E. T.; Gibson, J. R. & Suedhof, T. C. (2007)
Neuron, 54(6) pp. 919-931. DOI: https://doi.org/10.1016/j.neuron.2007.05.029
Details DOI PMID PMC WoS

2006 | Journal Article
Interaction between the vesicular glutamate transporter type 1 and endophilin A1, a protein essential for endocytosis
Vinatier, J.; Herzog, E.; Plamont, M. A.; Wojcik, S. M. ; Schmidt, A.; Brose, N. & Daviet, L. et al. (2006)
Journal of Neurochemistry, 97(4) pp. 1111-1125. DOI: https://doi.org/10.1111/j.1471-4159.2006.03821.x
Details DOI PMID PMC WoS

2006 | Journal Article | Research Paper
Neuroligins determine synapse maturation and function
Varoqueaux, F.; Aramuni, G.; Rawson, R. L.; Mohrmann, R.; Missler, M.; Gottmann, K. & Zhang, W. et al. (2006)
Neuron, 51(6) pp. 741-754. DOI: https://doi.org/10.1016/j.neuron.2006.09.003
Details DOI PMID PMC WoS

2006 | Journal Article | Research Paper
Synaptic and vesicular co-localization of the glutamate transporters VGLUT1 and VGLUT2 in the mouse hippocampus
Herzog, E.; Takamori, S.; Jahn, R. ; Brose, N. & Wojcik, S. M. (2006)
Journal of Neurochemistry, 99(3) pp. 1011-1018. DOI: https://doi.org/10.1111/j.1471-4159.2006.04144.x
Details DOI PMID PMC WoS

2006 | Journal Article | Research Paper
Munc13-1 deficiency reduces insulin secretion and causes abnormal glucose tolerance
Kwan, E. P.; Xie, L.; Sheu, L.; Nolan, C. J.; Prentki, M.; Betz, A. & Brose, N. et al. (2006)
Diabetes, 55(5) pp. 1421-1429. DOI: https://doi.org/10.2337/db05-1263
Details DOI PMID PMC WoS

2006 | Journal Article | Research Paper
Munc13-1 is required for the sustained release of insulin from pancreatic beta cells
Kang, L. J.; He, Z.; Xu, P Y; Fan, J. M.; Betz, A. ; Brose, N. & Xu, T. (2006)
Cell Metabolism, 3(6) pp. 463-468. DOI: https://doi.org/10.1016/j.cmet.2006.04.012
Details DOI PMID PMC WoS

2006 | Journal Article | Research Paper
A shared vesicular carrier allows synaptic corelease of GABA and glycine
Wojcik, S. M. ; Katsurabayashi, S.; Guillemin, I.; Friauf, E.; Rosenmund, C.; Brose, N. & Rhee, J.-S. (2006)
Neuron, 50(4) pp. 575-587. DOI: https://doi.org/10.1016/j.neuron.2006.04.016
Details DOI PMID PMC WoS

2006 | Journal Article | Research Paper
Binding to Rab3A-interacting molecule RIM regulates the presynaptic recruitment of Munc13-1 and ubMunc13-2
Andrews-Zwilling, Y. S.; Kawabe, H.; Reim, K.; Varoqueaux, F. & Brose, N. (2006)
Journal of biological chemistry, 281(28) pp. 19720-19731. DOI: https://doi.org/10.1074/jbc.M601421200
Details DOI PMID PMC WoS

2006 | Conference Paper | Research Paper
Characterization of the Munc13-calmodulin interaction by photoaffinity labeling
Dimova, K.; Kawabe, H.; Betz, A. ; Brose, N. & Jahn, O. (2006)
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. (11) (Vol. 1763). , Ecole Superieure Biotechnol, Strasbourg, FRANCE.
Amsterdam: Elsevier Science Bv. DOI: https://doi.org/10.1016/j.bbamcr.2006.09.017
Details DOI PMID PMC WoS

2006 | Journal Article | Research Paper
Molecular dynamics of a presynaptic active zone protein studied in Munc13-1-enhanced yellow fluorescent protein knock-in mutant mice
Kalla, S.; Stern, M.; Basu, J.; Varoqueaux, F.; Reim, K.; Rosenmund, C. & Ziv, N. E. et al. (2006)
The Journal of neuroscience, 26(50) pp. 13054-13066. DOI: https://doi.org/10.1523/JNEUROSCI.4330-06.2006
Details DOI PMID PMC WoS

2005 | Journal Article | Research Paper
Identification of the minimal protein domain required for priming activity of Munc13-1
Stevens, D. R.; Wu, Z X; Matti, U.; Junge, H. J.; Schirra, C.; Becherer, U. & Wojcik, S. M. et al. (2005)
Current Biology, 15(24) pp. 2243-2248. DOI: https://doi.org/10.1016/j.cub.2005.10.055
Details DOI PMID PMC WoS

2005 | Journal Article | Research Paper
Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse
Varoqueaux, F.; Sons, M. S.; Plomp, J. J. & Brose, N. (2005)
Molecular and Cellular Biology, 25(14) pp. 5973-5984. DOI: https://doi.org/10.1128/MCB.25.14.5973-5984.2005
Details DOI PMID PMC WoS

2005 | Journal Article | Research Paper
A similar impairment in CA3 mossy fibre LTP in the R6/2 mouse model of Huntington's disease and in the complexin II knockout mouse
Gibson, H. E.; Reim, K.; Brose, N. ; Morton, A. J. & Jones, S. (2005)
European Journal of Neuroscience, 22(7) pp. 1701-1712. DOI: https://doi.org/10.1111/j.1460-9568.2005.04349.x
Details DOI PMID PMC WoS

2005 | Journal Article
Structurally and functionally unique complexins at retinal ribbon synapses
Reim, K.; Wegmeyer, H.; Brandstaetter, J. H.; Xue, M.; Rosenmund, C.; Dresbach, T. & Hofmann, K. et al. (2005)
The Journal of Cell Biology, 169(4) pp. 669-680. DOI: https://doi.org/10.1083/jcb.200502115
Details DOI PMID PMC WoS

2005 | Journal Article | Research Paper
Profound ataxia in complexin I knockout mice masks a complex phenotype that includes exploratory and habituation deficits
Glynn, D.; Drew, C. J.; Reim, K.; Brose, N. & Morton, A. J. (2005)
Human Molecular Genetics, 14(16) pp. 2369-2385. DOI: https://doi.org/10.1093/hmg/ddi239
Details DOI PMID PMC WoS

2005 | Journal Article | Research Paper
Unchanged survival rates of 14-3-3 gamma knockout mice after inoculation with pathological prion protein
Steinacker, P. ; Schwarz, P.; Reim, K.; Brechlin, P.; Jahn, O. ; Kratzin, H. & Aitken, A. et al. (2005)
Molecular and Cellular Biology, 25(4) pp. 1339-1346. DOI: https://doi.org/10.1128/MCB.25.4.1339-1346.2005
Details DOI PMID PMC WoS

2005 | Journal Article | Research Paper
CAPS1 regulates catecholamine loading of large dense-core vesicles
Speidel, D.; Bruederle, C. E.; Enk, C.; Voets, T.; Varoqueaux, F.; Reim, K. & Becherer, U. et al. (2005)
Neuron, 46(1) pp. 75-88. DOI: https://doi.org/10.1016/j.neuron.2005.02.019
Details DOI PMID PMC WoS

2005 | Journal Article | Research Paper
Munc13-4 is an effector of Rab27a and controls secretion of lysosomes in hematopoietic cells
Neeft, M.; Wieffer, M.; Jong, A. S. de; Negroiu, G.; Metz, C. H. G.; van Loon, A. & Griffith, J. et al. (2005)
Molecular Biology of the Cell, 16(2) pp. 731-741. DOI: https://doi.org/10.1091/mbc.E04-10-0923
Details DOI PMID PMC WoS

2004 | Book Chapter
Transgenic mouse models in the analysis of neurotransmitter release mechanisms
Brose, N. & Rettig, J. (2004)
In:Hein, Lutz; Offermanns, S. (Eds.), Transgenic Models in Pharmacology pp. 229-261. Berlin: Springer.
Details

2004 | Journal Article | Research Paper
Munc13-1-mediated vesicle priming contributes to secretory amyloid precursor protein processing
Rossner, S.; Fuchsbrunner, K.; Lange-Dohna, C.; Hartlage-Rubsamen, M.; Bigl, V.; Betz, A. & Reim, K. et al. (2004)
Journal of biological chemistry, 279(27) pp. 27841-27844. DOI: https://doi.org/10.1074/jbc.C400122200
Details DOI PMID PMC WoS

2004 | Journal Article | Research Paper
Calmodulin and Munc13 form a Ca²⁺ sensor/effector complex that controls short-term synaptic plasticity
Junge, H. J.; Rhee, J.-S. ; Jahn, O. ; Varoqueaux, F.; Spiess, J. ; Waxham, M. N. & Rosenmund, C. et al. (2004)
Cell, 118(3) pp. 389-401. DOI: https://doi.org/10.1016/j.cell.2004.06.029
Details DOI PMID PMC WoS

2004 | Journal Article | Research Paper
An essential role for vesicular glutamate transporter 1 (VGLUT1) in postnatal development and control of quantal size
Wojcik, S. M. ; Rhee, J.-S. ; Herzog, E.; Sigler, A.; Jahn, R. ; Takamori, S. & Brose, N. et al. (2004)
Proceedings of the National Academy of Sciences, 101(18) pp. 7158-7163. DOI: https://doi.org/10.1073/pnas.0401764101
Details DOI PMID PMC WoS

2004 | Journal Article | Research Paper
Synaptic targeting of neuroligin is independent of neurexin and SAP90/PSD95 binding
Dresbach, T. ; Neeb, A.; Meyer, G.; Gundelfinger, E. D. & Brose, N. (2004)
Molecular and Cellular Neuroscience, 27(3) pp. 227-235. DOI: https://doi.org/10.1016/j.mcn.2004.06.013
Details DOI PMID PMC WoS

2004 | Journal Article | Research Paper
The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin
Meyer, G.; Varoqueaux, F.; Neeb, A.; Oschlies, M. & Brose, N. (2004)
Neuropharmacology, 47(5) pp. 724-733. DOI: https://doi.org/10.1016/j.neuropharm.2004.06.023
Details DOI PMID PMC WoS

2004 | Journal Article | Research Paper
Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25
Nagy, G.; Reim, K.; Matti, U.; Brose, N. ; Binz, T.; Rettig, J. & Neher, E. et al. (2004)
Neuron, 41(3) pp. 417-429. DOI: https://doi.org/10.1016/S0896-6273(04)00038-8
Details DOI PMID PMC WoS

2004 | Journal Article | Research Paper
Neuroligin 2 is exclusively localized to inhibitory synapses
Varoqueaux, F.; Jamain, S. & Brose, N. (2004)
European Journal of Cell Biology, 83(9) pp. 449-456. DOI: https://doi.org/10.1078/0171-9335-00410
Details DOI PMID PMC WoS

2004 | Review
Divergent and convergent signaling by the diacylglycerol second messenger pathway in mammals
Brose, N. ; Betz, A. & Wegmeyer, H. (2004)
Current Opinion in Neurobiology, 14(3) pp. 328-340.
Current Biology Ltd. DOI: https://doi.org/10.1016/j.conb.2004.05.006
Details DOI PMID PMC WoS

2003 | Journal Article | Research Paper
A brain-specific isoform of small glutamine-rich tetratricopeptide repeat-containing protein binds to Hsc70 and the cysteine string protein
Tobaben, S.; Varoqueaux, F.; Brose, N. ; Stahl, B. & Meyer, G. (2003)
Journal of biological chemistry, 278(40) pp. 38376-38383. DOI: https://doi.org/10.1074/jbc.M301558200
Details DOI PMID PMC WoS

2003 | Journal Article | Research Paper
A family of Ca²⁺-dependent activator proteins for secretion. Comparative analysis of structure, expression, localization, and function
Speidel, D.; Varoqueaux, F.; Enk, C.; Nojiri, M.; Grishanin, R. N.; Martin, T. F. J. & Hofmann, K. et al. (2003)
Journal of biological chemistry, 278(52) pp. 52802-52809. DOI: https://doi.org/10.1074/jbc.M304727200
Details DOI PMID PMC WoS

2003 | Journal Article | Research Paper
Differential control of the releasable vesicle pools by SNAP-25 splice variants and SNAP-23
Sørensen, J. B.; Nagy, G.; Varoqueaux, F.; Nehring, R. B.; Brose, N. ; Wilson, M C & Neher, E. (2003)
Cell, 114(1) pp. 75-86. DOI: https://doi.org/10.1016/S0092-8674(03)00477-X
Details DOI PMID PMC WoS

2003 | Review
Molecular mechanisms of active zone function
Rosenmund, C.; Rettig, J.& Brose, N. (2003)
Current Opinion in Neurobiology, 13(5) pp. 509-519.
Current Biology Ltd. DOI: https://doi.org/10.1016/j.conb.2003.09.011
Details DOI PMID PMC WoS

2003 | Journal Article | Letter Note
SPARring with spines
Meyer, G. & Brose, N. (2003)
Science, 302(5649) pp. 1341-+. DOI: https://doi.org/10.1126/science.1092039
Details DOI PMID PMC WoS

2003 | Journal Article | Research Paper
Regulation of insulin exocytosis by Munc13-1
Sheu, L.; Pasyk, E. A.; Ji, J. .Z; Haung, X. H.; Gao, X.; Varoqueaux, F. & Brose, N. et al. (2003)
Journal of biological chemistry, 278(30) pp. 27556-27563. DOI: https://doi.org/10.1074/jbc.M303203200
Details DOI PMID PMC WoS

2002 | Book Chapter
Synaptogenesis
Brose, N. & Varoqueaux, F. (2002)
In:Ramachandran, V. S. (Ed.), Encyclopedia of the human brain pp. 531-544. (Vol. 4). Amsterdam: Elsevier.
Details

2002 | Journal Article | Letter Note
Specificity emerges in the dissection of diacylglycerol- and protein kinase C-mediated signalling pathways
Brose, N. & Neher, E. (2002)
Proceedings of the National Academy of Sciences, 99(26) pp. 16522-16523. DOI: https://doi.org/10.1073/pnas.022708199
Details DOI PMID PMC WoS

2002 | Journal Article | Research Paper
Differential control of vesicle priming and short-term plasticity by Munc13 isoforms
Rosenmund, C.; Sigler, A.; Augustin, I.; Reim, K.; Brose, N. & Rhee, J.-S. (2002)
Neuron, 33(3) pp. 411-424. DOI: https://doi.org/10.1016/S0896-6273(02)00568-8
Details DOI PMID PMC WoS

2002 | Review
Move over protein kinase C, you've got company: Alternative cellular effectors of diacylglycerol and phorbol esters
Brose, N. & Rosenmund, C. (2002)
Journal of Cell Science, 115(23) pp. 4399-4411.
Company Of Biologists Ltd. DOI: https://doi.org/10.1242/jcs.00122
Details DOI PMID PMC WoS

2002 | Journal Article | Research Paper
Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming
Varoqueaux, F.; Sigler, A.; Rhee, J.-S. ; Brose, N. ; Enk, C.; Reim, K. & Rosenmund, C. (2002)
Proceedings of the National Academy of Sciences, 99(13) pp. 9037-9042. DOI: https://doi.org/10.1073/pnas.122623799
Details DOI PMID PMC WoS

2002 | Journal Article | Research Paper
β Phorbol Ester- and Diacylglycerol-Induced Augmentation of Transmitter Release Is Mediated by Munc13s and Not by PKCs
Rhee, J.-S. ; Betz, A. ; Pyott, S.; Reim, K.; Varoqueaux, F.; Augustin, I. & Hesse, D. et al. (2002)
Cell, 108(1) pp. 121-133. DOI: https://doi.org/10.1016/S0092-8674(01)00635-3
Details DOI PMID PMC WoS

2002 | Journal Article | Research Paper
Loss of the zymogen granule protein syncollin affects pancreatic protein synthesis and transport but not secretion
Antonin, W.; Wagner, M.; Riedel, D. ; Brose, N. & Jahn, R. (2002)
Molecular and Cellular Biology, 22(5) pp. 1545-1554. DOI: https://doi.org/10.1128/MCB.22.5.1545-1554.2002
Details DOI PMID PMC WoS

2001 | Journal Article | Research Paper
The synaptic vesicle priming protein Munc13-1 is absent from tonically active ribbon synapses of the rat retina
Schmitz, F.; Augustin, I. & Brose, N. (2001)
Brain Research, 895(1-2) pp. 258-263. DOI: https://doi.org/10.1016/S0006-8993(01)02078-9
Details DOI PMID PMC WoS

2001 | Journal Article | Research Paper
Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming
Betz, A. ; Thakur, P.; Junge, H. J.; Ashery, U.; Rhee, J.-S. ; Scheuss, V. & Rosenmund, C. et al. (2001)
Neuron, 30(1) pp. 183-196. DOI: https://doi.org/10.1016/S0896-6273(01)00272-0
Details DOI PMID PMC WoS

2001 | Journal Article | Research Paper
Synaptotagmin I functions as a calcium regulator of release probability
Fernandez-Chacon, R.; Königstorfer, A.; Gerber, S. H.; Garcia, J.; Matos, M. F.; Stevens, C. F. & Brose, N. et al. (2001)
Nature, 410(6824) pp. 41-49. DOI: https://doi.org/10.1038/35065004
Details DOI PMID PMC WoS

2001 | Journal Article | Research Paper
Complexins regulate a late step in Ca²⁺-dependent neurotransmitter release
Reim, K.; Mansour, M.; Varoqueaux, F.; McMahon, H. T.; Südhof, T. C.; Brose, N. & Rosenmund, C. (2001)
Cell, 104(1) pp. 71-81. DOI: https://doi.org/10.1016/S0092-8674(01)00192-1
Details DOI PMID PMC WoS

2001 | Journal Article | Research Paper
The Cerebellum-Specific Munc13 Isoform Munc13-3 Regulates Cerebellar Synaptic Transmission and Motor Learning in Mice
Augustin, I.; Korte, S.; Rickmann, M.; Kretzschmar, H. A.; Südhof, T. C.; Herms, J. W. & Brose, N. (2001)
The Journal of Neuroscience, 21(1) pp. 10-17. DOI: https://doi.org/10.1523/JNEUROSCI.21-01-00010.2001
Details DOI PMID PMC WoS

2000 | Journal Article | Research Paper
Munc13-1 acts as a priming factor for large dense-core vesicles in bovine chromaffin cells
Ashery, U.; Varoqueaux, F.; Voets, T.; Betz, A. ; Koch, H.; Neher, E. & Brose, N. et al. (2000)
EMBO Journal, 19(14) pp. 3586-3596. DOI: https://doi.org/10.1093/emboj/19.14.3586
Details DOI PMID PMC WoS

2000 | Review
Regulation of transmitter release by Unc-13 and its homologues
Brose, N. ; Rosenmund, C.& Rettig, J. (2000)
Current Opinion in Neurobiology, 10(3) pp. 303-311.
Current Biology Ltd. DOI: https://doi.org/10.1016/S0959-4388(00)00105-7
Details DOI PMID PMC WoS

2000 | Journal Article | Research Paper
Definition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13 isoform
Koch, H.; Hofmann, K. & Brose, N. (2000)
Biochemical Journal, 349 pp. 247-253. DOI: https://doi.org/10.1042/0264-6021:3490247
Details DOI PMID PMC WoS

1999 | Journal Article
An efficient method for infection of adrenal chromaffin cells using the Semliki Forest virus gene express1on system
Ashery, U.; Betz, A.; Xu, T.; Brose, N. & Rettig, J. (1999)
European Journal of Cell Biology, 78(8) pp. 525-532. DOI: https://doi.org/10.1016/S0171-9335(99)80017-X
Details DOI

1999 | Journal Article | Research Paper
A presynaptic role for the ADP ribosylation factor (ARF)-specific GDP/GTP exchange factor msec7-1
Ashery, U.; Koch, H.; Scheuss, V.; Brose, N. & Rettig, J. (1999)
Proceedings of the National Academy of Sciences, 96(3) pp. 1094-1099. DOI: https://doi.org/10.1073/pnas.96.3.1094
Details DOI PMID PMC WoS

1999 | Review
Synaptic cell adhesion proteins and synaptogenesis in the mammalian central nervous system
Brose, N. (1999)
Naturwissenschaften, 86(11) pp. 516-524.
Springer. DOI: https://doi.org/10.1007/s001140050666
Details DOI PMID PMC WoS

1999 | Journal Article | Research Paper
Differential expression of two novel Munc13 proteins in rat brain
Augustin, I.; Betz, A. ; Herrmann, C. ; Jo, T. & Brose, N. (1999)
Biochemical Journal, 337 pp. 363-371. DOI: https://doi.org/10.1042/0264-6021:3370363
Details DOI PMID PMC WoS

1999 | Journal Article | Research Paper
Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses
Song, J. Y.; Ichtchenko, K.; Südhof, T. C. & Brose, N. (1999)
Proceedings of the National Academy of Sciences, 96(3) pp. 1100-1105. DOI: https://doi.org/10.1073/pnas.96.3.1100
Details DOI PMID PMC WoS

1999 | Journal Article | Research Paper
Evidence of presynaptic location and function of the prion protein
Herms, J.; Tings, T.; Gall, S.; Madlung, A.; Giese, A.; Siebert, H. & Schurmann, P. et al. (1999)
The Journal of neuroscience, 19(20) pp. 8866-8875. DOI: https://doi.org/10.1523/JNEUROSCI.19-20-08866.1999
Details DOI PMID PMC WoS

1999 | Journal Article | Letter Note
SV2: SVeeping up excess Ca²⁺ or TranSVorming presynaptic Ca²⁺ sensors?
Brose, N. & Rosenmund, C. (1999)
Neuron, 24(4) pp. 766-768. DOI: https://doi.org/10.1016/S0896-6273(00)81023-5
Details DOI PMID PMC WoS

1999 | Journal Article | Research Paper
Direct interaction between the ARF-specific guanine nucleotide exchange factor msec7-1 and presynaptic Munc13-1
Neeb, A.; Brose, N. ; Koch, H. & Schürmann, A. (1999)
European Journal of Cell Biology, 78(8) pp. 533-538. DOI: https://doi.org/10.1016/s0171-9335(99)80018-1
Details DOI PMID PMC WoS

1999 | Journal Article | Research Paper
Transient, phorbol ester-induced DOC2-Munc13 interactions in vivo
Duncan, R. R.; Betz, A. ; Shipston, M. J.; Brose, N. & Chow, R. H. (1999)
Journal of Biological Chemistry, 274(39) pp. 27347-27350. DOI: https://doi.org/10.1074/jbc.274.39.27347
Details DOI PMID PMC WoS

1999 | Journal Article | Research Paper
Munc13-1 is essential for fusion competence of glutamatergic synoptic vesicles
Augustin, I.; Rosenmund, C.; Suedhof, T. C. & Brose, N. (1999)
Nature, 400(6743) pp. 457-461. DOI: https://doi.org/10.1038/22768
Details DOI PMID PMC WoS

1999 | Journal Article | Research Paper
An efficient method for infection of adrenal chromaffin cells using the Semliki Forest virus gene expression system
Ashery, U.; Betz, A. ; Brose, N. ; Rettig, J. & Xu, T. (1999)
European Journal of Cell Biology, 78(8) pp. 525-532. DOI: https://doi.org/10.1016/s0171-9335(99)80017-x
Details DOI PMID PMC WoS

1998 | Book Chapter
Synaptic vesicle proteins: A Molecular Study
Brose, N. (1998)
In:Linial, M.; Grasso, A.; Lazarovici, M. (Eds.), Cellular and Molecular Mechanisms of Toxin Action - Secretory Systems and Toxins pp. 45-62. (1. ed.). Florida: CRC Press.
Details

1998 | Journal Article | Research Paper
Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release
Betz, A. ; Ashery, U.; Rickmann, M. ; Augustin, I.; Neher, E. ; Südhof, T. C. & Rettig, J. et al. (1998)
Neuron, 21(1) pp. 123-136. DOI: https://doi.org/10.1016/S0896-6273(00)80520-6
Details DOI PMID PMC WoS

1997 | Journal Article | Research Paper
Rat homologues of yeast sec7p
Telemenakis, I. ; Benseler, F. ; Stenius, K.; Südhof, T. C. & Brose, N. (1997)
European Journal of Cell Biology, 74(2) pp. 143-149.
Details PMID PMC WoS

1997 | Book Chapter
Genetic approaches in the analysis of synpatic function
Brose, N. & Geppert, M. (1997)
In:Wässle, H.; Elsner, N. (Eds.), From membrane to mind : proceedings of the 25th Göttingen Neurobiology Conference pp. 274-276. Stuttgart: Georg Thieme Verlag.
Details

1997 | Journal Article
Direct Interaction of the Rat unc-13 Homologue Munc13-1 with the N Terminus of Syntaxin
Okamoto, M.; Brose, N. & Betz, A. (1997)
Journal of biological chemistry, 272(4) pp. 2520-2526. DOI: https://doi.org/10.1074/jbc.272.4.2520
Details DOI

1996 | Journal Article | Research Paper
Fatty acylation of synaptotagmin in PC12 cells and synaptosomes
Chapman, E. R.; Blasi, J.; An, S.; Brose, N. ; Johnston, P.; Suedhof, T. C. & Jahn, R. (1996)
Biochemical and Biophysical Research Communications, 225(1) pp. 326-332. DOI: https://doi.org/10.1006/bbrc.1996.1174
Details DOI PMID PMC WoS

1995 | Journal Article
Mammalian Homologues of Caenorhabditis elegans unc-13 Gene Define Novel Family of C2-domain Proteins
Brose, N. ; Hofmann, K.; Hata, Y. & Suedhof, T. C. (1995)
Journal of biological chemistry, 270(42) pp. 25273-25280. DOI: https://doi.org/10.1074/jbc.270.42.25273
Details DOI

1995 | Journal Article | Research Paper
Ca²⁺-dependent and -independent activities of neural and non-neural synaptotagmins
Li, C.; Ullrich, B.; Zhang, J. Z.; Anderson, R. G. W.; Brose, N. & Südhof, T. C. (1995)
Nature, 375(6532) pp. 594-599. DOI: https://doi.org/10.1038/375594a0
Details DOI PMID PMC WoS

1994 | Journal Article | Research Paper
Immunolocalization of NMDA receptors in the central nervous system of weakly electric fish: functional implications for the modulation of a neuronal oscillator
Spiro, J. E.; Brose, N. ; Heinemann, S. F. & Heiligenberg, W. (1994)
The Journal of neuroscience, 14(10) pp. 6289-6299.
Details PMID PMC WoS

1994 | Journal Article | Research Paper
Differential assembly of coexpressed glutamate receptor subunits in neurons of rat cerebral cortex
Brose, N. ; Huntley, G. W.; Sternbach, Y.; Sharma, G.; Morrison, J. H. & Heinemann, S. F. (1994)
Journal of biological chemistry, 269(24) pp. 16780-16784.
Details PMID PMC WoS

1994 | Journal Article
Rapid Communication Chronic Ingestion of Ethanol Up-Regulates NMDAR1 Receptor Subunit Immunoreactivity in Rat Hippocampus
Trevisan, L.; Fitzgerald, L. W.; Brose, N. ; Gasic, G. P.; Heinemann, S. F.; Duman, R. S. & Nestler, E. J. (1994)
Journal of Neurochemistry, 62(4) pp. 1635-1638. DOI: https://doi.org/10.1046/j.1471-4159.1994.62041635.x
Details DOI

1994 | Journal Article
Chronic ingestion of ethanol up-regulates NMDAR1 receptor subunit immunoreactivity in rat hippocampus
Trevisan, L.; Fitzgerald, L. W.; Brose, N. ; Gasic, G. P.; Heinemann, S. F.; Duman, R. S. & Nestler, E. J. (1994)
Journal of Neurochemistry, 62(4) pp. 1635-1638.
Details PMID PMC WoS

1994 | Review
Distribution and synaptic localization of immunocytochemically identified NMDA receptor subunit proteins in sensory-motor and visual cortices of monkey and human
Huntley, G. W.; Vickers, J. C.; Janssen, W.; Brose, N. ; Heinemann, S. F.& Morrison, J. H. (1994)
The Journal of neuroscience, 14(6) pp. 3603-3619.
Soc Neuroscience.
Details PMID PMC WoS

1994 | Journal Article | Research Paper
Expression of the NMDA R1 receptor in selected human brain regions
Böckers, T. M.; Zimmer, M.; Müller, A.; Bergmann, M.; Brose, N. & Kreutz, M. R. (1994)
NeuroReport, 5(8) pp. 965-969.
Details PMID PMC WoS

1994 | Journal Article | Research Paper
Selective RNA editing and subunit assembly of native glutamate receptors
Puchalski, R. B.; Louis, J.-C.; Brose, N. ; Traynelis, S. F.; Egebjerj, J.; Kukekov, V. & Wenthold, R. J. et al. (1994)
Neuron, 13(1) pp. 131-147. DOI: https://doi.org/10.1016/0896-6273(94)90464-2
Details DOI PMID PMC WoS

1994 | Journal Article | Research Paper
Regional, cellular, and ultrastructural distribution of N-methyl-D-aspartate receptor subunit 1 in monkey hippocampus
Siegel, S. J.; Brose, N. ; Janssen, W.; Gasic, G. P.; Jahn, R. ; Heinemann, S. F. & Morrison, J. H. (1994)
Proceedings of the National Academy of Sciences, 91(2) pp. 564-568. DOI: https://doi.org/10.1073/pnas.91.2.564
Details DOI PMID PMC WoS

1993 | Journal Article | Research Paper
Expression of endogenous NMDAR1 transcripts without receptor protein suggests post-transcriptional control in PC12 cells
Sucher, N. J.; Brose, N. ; Deitcher, D. L.; Awobuluyi, M.; Gasic, G. P.; Bading, H. & Cepko, C. L. et al. (1993)
Journal of Biological Chemistry, 268(30) pp. 22299-22304.
Details PMID PMC WoS

1993 | Journal Article | Research Paper
Protein chemical characterization and immunocytochemical localization of the NMDA receptor subunit NMDA R1
Brose, N. ; Gasic, G. P.; Vetter, D. E.; Sullivan, J. M. & Heinemann, S. F. (1993)
Journal of biological chemistry, 268(30) pp. 22663-22671.
Details PMID PMC WoS

1993 | Review
Membrane fusion takes excitatory turn: Syntaxin, vesicle docking protein, or glutamate receptor?
Brose, N. (1993)
Cell, 75(6) pp. 1043-1044.
Cambridge: Cell Press. DOI: https://doi.org/10.1016/0092-8674(93)90313-F
Details DOI PMID PMC WoS

1992 | Journal Article | Research Paper
Synaptotagmin: a calcium sensor on the synaptic vesicle surface
Brose, N. ; Petrenko, A. G.; Suedhof, T. C. & Jahn, R. (1992)
Science, 256(5059) pp. 1021-1025. DOI: https://doi.org/10.1126/science.1589771
Details DOI PMID PMC WoS

1991 | Journal Article | Research Paper
Domain structure of synaptotagmin (p65)
Perin, M. S.; Brose, N. ; Jahn, R. & Südhof, T. C. (1991)
Journal of biological chemistry, 266(1) pp. 623-629.
Details PMID PMC WoS

1990 | Journal Article | Research Paper
A chloride- and calcium-dependent glutamate-binding protein from rat brain. Identification as a ubiquitous constituent of the inner mitochondrial membrane
Brose, N. ; Thomas, A.; Weber, M. G. & Jahn, R. (1990)
Journal of biological chemistry, 265(18) pp. 10604-10610.
Details PMID PMC WoS

1989 | Journal Article | Research Paper
Characterization and partial purification of a chloride- and calcium-dependent glutamate-binding protein from rat brain.
Brose, N. ; Halpain, S.; Suchanek, C. & Jahn, R. (1989)
Journal of biological chemistry, 264(16) pp. 9619-9625.
Details PMID PMC WoS

1989 | Journal Article | Research Paper
The effects of anxiolytic and anxiogenic benzodiazepine receptor ligands on motor activity and levels of ascorbic acid in the nucleus accumbens and striatum of the rat
Brose, N. ; O'Neill, R. D.; Boutelle, M. G. & Fillenz, M. (1989)
Neuropharmacology, 28(5) pp. 509-514. DOI: https://doi.org/10.1016/0028-3908(89)90087-7
Details DOI PMID PMC WoS

1988 | Journal Article | Research Paper
Dopamine in the basal ganglia and benzodiazepine-induced sedation
Brose, N. ; O'Neill, R. D.; Boutelle, M. G. & Fillenz, M. (1988)
Neuropharmacology, 27(6) pp. 589-595. DOI: https://doi.org/10.1016/0028-3908(88)90179-7
Details DOI PMID PMC WoS

1987 | Journal Article | Research Paper
Effects of an anxiogenic benzodiazepine receptor ligand on motor activity and dopamine release in nucleus accumbens and striatum in the rat.
Brose, N. ; O'Neill, R. D.; Boutelle, M. G.; Anderson, S. M. P. & Fillenz, M. (1987)
The Journal of neuroscience, 7(9) pp. 2917-2926.
Details PMID PMC WoS

Publication List

All Articles (Book & Journal) Conference objects Books & Book chapters Book chapters & Review Articles & Preprints Papers (Journal & Conference)

Type

Subtype

Date issued

Author

Project

Peer-Reviewed

Organization

Language

Fulltext

Options

Citation Style

GRO View APA Chicago MLA Vancouver

https://publications.goettingen-research-online.de URI: /cris/rp/rp00021
ID: 0000000
PREF: default TOKEN:

Sort

Issue Date

ASC DESC

Title

ASC DESC

Embed

JavaScript

                                     <script type="text/javascript" charset="UTF-8" src="https://publications.goettingen-research-online.de/cris/rp/rp00021?open=all1&rppall=1000&etalall=-1&startall=0&ft=js&cs=default"></script>

Link

                                 <a id="grolink" href="//publications.goettingen-research-online.de/cris/rp/rp00021?open=all1&rppall=1000&etalall=-1&startall=0&" target="_blank">My Publication</a>

Export

Activate Export Mode

Deactivate Export Mode

Select some or all items (max. 800 for CSV/Excel) from the publications list, then choose an export format below.

Please first select the desired publications for export.