Author Matthaei, Johannes

• 2015 | Conference Abstract
  ​ ​OCT1 is the clinically relevant hepatic transporter of sumatriptan: in vitro and in vivo evidences​
  Kuron, D.; Matthaei, J.; Brockmoeller, J. & Tzvetkov, M. V.​ (2015)
  Naunyn-Schmiedeberg s Archives of Pharmacology, 388 ​81st Annual Meeting of the Deutsche-Gesellschaft-fur-Experimentelle-und-Klinische-Pharmakologie-und Toxikologie-e-V​, Kiel, GERMANY.
  New york​: Springer.
  ​Details  WoS 

• 2016 | Journal Article
  ​ ​OCT1 Mediates Hepatic Uptake of Sumatriptan and Loss-of-Function OCT1 Polymorphisms Affect Sumatriptan Pharmacokinetics​
  Matthaei, J.; Kuron, D.; Faltraco, F.; Knoch, T.; Pereira, J. N. D. S.; Abu Abed, M. & Prukop, T. et al.​ (2016) 
  Clinical Pharmacology & Therapeutics, 99(6) pp. 633​-641​.​ DOI: https://doi.org/10.1002/cpt.317 
  ​Details  DOI  PMID  PMC  WoS 

• 2016 | Journal Article | 
  ​ ​Low heritability in pharmacokinetics of talinolol: a pharmacogenetic twin study on the heritability of the pharmacokinetics of talinolol, a putative probe drug of MDR1 and other membrane transporters​
  Matthaei, J.; Tzvetkov, M. V.; Gal, V.; Sachse-Seeboth, C.; Sehrt, D.; Hjelmborg, J. B. & Hofmann, U. et al.​ (2016) 
  Genome Medicine, 8 art. 119​.​ DOI: https://doi.org/10.1186/s13073-016-0372-2 
  ​Details  DOI  PMID  PMC  WoS 

• 2021 | Journal Article
  ​ ​Effects of a Common Eight Base Pairs Duplication at the Exon 7-Intron 7 Junction on Splicing, Expression, and Function of OCT1​
  Römer, S.; Meyer, M. J.; Klein, K.; Schneider, L. V.; Matthaei, J.; Tzvetkova, A. & Łapczuk-Romańska, J. et al.​ (2021) 
  Frontiers in Pharmacology, 12.​ DOI: https://doi.org/10.3389/fphar.2021.661480 
  ​Details  DOI 

• 2021 | Journal Article | Research Paper | 
  ​ ​Isobutyrylcarnitine as a Biomarker of OCT1 Activity and Interspecies Differences in its Membrane Transport​
  Jensen, O.; Matthaei, J.; Klemp, H. G.; Meyer, M. J.; Brockmöller, J. & Tzvetkov, M. V.​ (2021) 
  Frontiers in Pharmacology, 12.​ DOI: https://doi.org/10.3389/fphar.2021.674559 
  ​Details  DOI 

• 2021 | Journal Article | Research Paper | 
  ​ ​Effects of Genetic Polymorphism in CYP2D6, CYP2C19, and the Organic Cation Transporter OCT1 on Amitriptyline Pharmacokinetics in Healthy Volunteers and Depressive Disorder Patients​
  Steimer, W.; Pischa, K.; Leucht, S.; Kullmann, M.; Ouethy, T.; Rafehi, M.   & Matthaei, J. et al.​ (2021) 
  Frontiers in Pharmacology, 12.​ DOI: https://doi.org/10.3389/fphar.2021.688950 
  ​Details  DOI 

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