Author Giese, Armin
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1999 | Journal Article | Research Paper
Evidence of presynaptic location and function of the prion protein
Herms, J.; Tings, T.; Gall, S.; Madlung, A.; Giese, A.; Siebert, H. & Schurmann, P. et al. (1999)
The Journal of neuroscience, 19(20) pp. 8866-8875. DOI: https://doi.org/10.1523/JNEUROSCI.19-20-08866.1999
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2009 | Journal Article |
Incidence and spectrum of sporadic Creutzfeldt-Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification
Parchi, P.; Strammiello, R.; Notari, S.; Giese, A.; Langeveld, J. P. M.; Ladogana, A. & Zerr, I. et al. (2009)
Acta Neuropathologica, 118(5) pp. 659-671. DOI: https://doi.org/10.1007/s00401-009-0585-1
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2010 | Journal Article
Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1
Kamp, F.; Exner, N.; Lutz, A. K.; Wender, N.; Hegermann, J.; Brunner, B. & Nuscher, B. et al. (2010)
The EMBO Journal, 29(20) pp. 3571-3589. DOI: https://doi.org/10.1038/emboj.2010.223
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2010 | Journal Article
Agent strain variation in human prion disease: insights from a molecular and pathological review of the National Institutes of Health series of experimentally transmitted disease
Parchi, P.; Cescatti, M.; Notari, S.; Schulz-Schaeffer, W. J.; Capellari, S.; Giese, A. & Zou, W.-Q. et al. (2010)
Brain, 133 pp. 3030-3042. DOI: https://doi.org/10.1093/brain/awq234
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2011 | Journal Article
Comprehensive Neuropathologic Analysis of Genetic Prion Disease Associated With the E196K Mutation in PRNP Reveals Phenotypic Heterogeneity
Eigenbrod, S.; Frick, P.; Giese, A.; Schelzke, G.; Zerr, I. & Kretzschmar, H. A. (2011)
Journal of Neuropathology and Experimental Neurology, 70(3) pp. 192-200. DOI: https://doi.org/10.1097/NEN.0b013e31820cd8a4
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2014 | Journal Article | Letter Note |
The oligomer modulator anle138b inhibits disease progression in a Parkinson mouse model even with treatment started after disease onset
Levin, J.; Schmidt, F.; Boehm, C.; Prix, C.; Boetzel, K.; Ryazanov, S. & Leonov, A. et al. (2014)
Acta Neuropathologica, 127(5) pp. 779-780. DOI: https://doi.org/10.1007/s00401-014-1265-3
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2015 | Conference Abstract
Assessing the pathogenicity of rare PRNP variants by comparing case and control allele frequency
Minikel, E. V.; Vallabh, S. M.; Lek, M.; Estrada, K. O.; Samocha, K. E.; Sathirapongsasuti, J. F. & McLean, C. Y. et al. (2015)
Prion, 9 pp. S90-S91.
Philadelphia: Taylor & Francis Inc.
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2015 | Journal Article
The Novel Inhibitor “Anle145C” Efficiently Inhibits Fibril Formation of Islet Amyloid Polypeptide (IAPP) and uses Distinctly Different Modes of Action in the Absence and Presence of Membranes
Saravanan, M. S.; Ryazanov, S.; Leonov, A.; Seeliger, J.; Winter, R.; Giese, A. & Griesinger, C. et al. (2015)
Biophysical Journal, 108(2) pp. 256a. DOI: https://doi.org/10.1016/j.bpj.2014.11.1416
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2015 | Journal Article | Research Paper |
Extracellular vesicle sorting of alpha-Synuclein is regulated by sumoylation
Kunadt, M.; Eckermann, K.; Stuendl, A.; Gong, J.; Russo, B.; Strauss, K. & Rai, S. et al. (2015)
Acta Neuropathologica, 129(5) pp. 695-713. DOI: https://doi.org/10.1007/s00401-015-1408-1
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2015 | Journal Article | Research Paper
Quantitative Real-Time Quaking-Induced Conversion Allows Monitoring of Disease-Modifying Therapy in the Urine of Prion-Infected Mice
Shi, S.; Wagner, J. ; Mitteregger-Kretzschmar, G.; Ryazanov, S. ; Leonov, A. ; Griesinger, C. & Giese, A. (2015)
Journal of Neuropathology and Experimental Neurology, 74(9) pp. 924-933. DOI: https://doi.org/10.1097/NEN.0000000000000233
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2015 | Journal Article | Research Paper
Anle138b and related compounds are aggregation specific fluorescence markers and reveal high affinity binding to ot-synuclein aggregates
Deeg, A. A.; Reiner, A. M.; Schmidt, F.; Schueder, F.; Ryazanov, S. ; Ruf, V. C. & Giller, K. et al. (2015)
Biochimica et Biophysica Acta (BBA) - General Subjects, 1850(9) pp. 1884-1890. DOI: https://doi.org/10.1016/j.bbagen.2015.05.021
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2016 | Journal Article
Effect of the Novel Amyloid Inhibitor “anle145c” on Aggregation of Islet Amyloid Polypeptide and how it is Modulated by Membranes
Sadasivam, S. M.; Ryazanov, S. ; Leonov, A. ; Roeters, S.; Wouterson, S.; Giese, A. & Griesinger, C. et al. (2016)
Biophysical Journal, 110(3) art. 420a. DOI: https://doi.org/10.1016/j.bpj.2015.11.2271
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2016 | Journal Article | Research Paper |
Anle138b Partly Ameliorates Motor Deficits Despite Failure of Neuroprotection in a Model of Advanced Multiple System Atrophy
Fellner, L.; Kuzdas-Wood, D.; Levin, J.; Ryazanov, S. ; Leonov, A. ; Griesinger, C. & Giese, A. et al. (2016)
Frontiers in Neuroscience, 10 art. 99. DOI: https://doi.org/10.3389/fnins.2016.00099
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2016 | Journal Article |
The PROMESA-protocol: progression rate of multiple system atrophy under EGCG supplementation as anti-aggregation-approach (vol 123, pg 439, 2016)
Levin, J.; Maass, S.; Schuberth, M.; Respondek, G.; Paul, F.; Mansmann, U. & Oertel, W. H. et al. (2016)
Journal of Neural Transmission, 123(11) pp. 1357-1358. DOI: https://doi.org/10.1007/s00702-016-1602-x
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2016 | Journal Article
Quantifying prion disease penetrance using large population control cohorts
Minikel, E. V.; Vallabh, S. M.; Lek, M.; Estrada, K. O.; Samocha, K. E.; Sathirapongsasuti, J. F. & McLean, C. Y. et al. (2016)
Science Translational Medicine, 8(322) art. 322ra9. DOI: https://doi.org/10.1126/scitranslmed.aad5169
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2017 | Journal Article
Treatment with diphenyl–pyrazole compound anle138b/c reveals that α-synuclein protects melanoma cells from autophagic cell death
Turriani, E.; Lázaro, D. F. ; Ryazanov, S. ; Leonov, A. ; Giese, A.; Schön, M. & Schön, M. P. et al. (2017)
Proceedings of the National Academy of Sciences of the United States of America, 114(25) pp. E4971-E4977. DOI: https://doi.org/10.1073/pnas.1700200114
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2017 | Journal Article
Photophysics of diphenyl-pyrazole compounds in solutions and α-synuclein aggregates
Reiner, A. M.; Schmidt, F.; Ryazanov, S. ; Leonov, A. ; Weckbecker, D.; Deeg, A. A. & Griesinger, C. et al. (2017)
Biochimica et Biophysica Acta (BBA) - General Subjects, 1862(4) pp. 800-807. DOI: https://doi.org/10.1016/j.bbagen.2017.12.007
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2017 | Journal Article
Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria
Höglinger, G.; Respondek, G.; Stamelou, M.; Kurz, C.; Josephs, K.; Lang, A. & Mollenhauer, B. et al. (2017)
Movement Disorders, 32(6) pp. 853-864. DOI: https://doi.org/10.1002/mds.26987
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2017 | Journal Article
Which ante mortem clinical features predict progressive supranuclear palsy pathology?
Respondek, G.; Kurz, C.; Arzberger, T.; Compta, Y.; Englund, E.; Ferguson, L. & Gelpi, E. et al. (2017)
Movement Disorders, 32(7) pp. 995-1005. DOI: https://doi.org/10.1002/mds.27034
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2017 | Journal Article |
The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology
Martinez-Hernandez, A. ; Urbanke, H. ; Gillman, A. L.; Lee, J.; Ryazanov, S. ; Agbemenyah, H. Y. & Benito, E. et al. (2017)
EMBO molecular medicine, 10(1) pp. 32-47. DOI: https://doi.org/10.15252/emmm.201707825
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