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Zeitschriftenartikel
Determination of the Biological Activity and Structure Activity Relationships of Drugs Based on the Highly Cytotoxic Duocarmycins and CC-1065
(2009)
The natural antibiotics CC-1065 and the duocarmycins are highly cytotoxic
compounds which however are not suitable for cancer therapy due to their general toxicity.
We have developed glycosidic prodrugs of seco-analogues ...
Zeitschriftenartikel
Des Palladiums kleiner Bruder: Neues aus der Nickel-Katalyse
(2011)
Thema des Nobelpreises für Chemie 2010 waren die palladiumkatalysierten Kupplungsreaktionen.
Was aber kann der kleinere Bruder des Palladiums – das Nickel – in der synthetischen organischen
Chemie leisten? Befindet sich ...
Zeitschriftenartikel
To π or not to π - how does methanol dock onto anisole?
(2015-05-06)
Anisole offers two similarly attractive hydrogen bond acceptor sites to an incoming hydrogen bond donor: its oxygen atom and its delocalized π electron system. Electronic structure calculations up to the CCSD(T)/AVTZ level ...
Zeitschriftenartikel
Hirshfeld atom refinement.
(2014-09-01)
Hirshfeld atom refinement (HAR) is a method which determines structural parameters from single-crystal X-ray diffraction data by using an aspherical atom partitioning of tailor-made ab initio quantum mechanical molecular ...
Zeitschriftenartikel
Solution structures of alkali metal cyclopentadienides in THF estimated by ECC-DOSY NMR-spectroscopy (incl. software).
(2016-10-12)
In this paper we present the aggregational motifs of the widely used alkali-metal cyclopentadienides (CpLi, CpNa, CpK, CpRb, CpCs) in THF-d8 solution estimated by ECC-DOSY NMR spectroscopy. They form monomeric contact ion ...
Zeitschriftenartikel
Evolution of atomic structure during nanoparticle formation.
(2014-05-01)
Understanding the mechanism of nanoparticle formation during synthesis is a key prerequisite for the rational design and engineering of desirable materials properties, yet remains elusive due to the difficulty of studying ...
Zeitschriftenartikel
Structure and crystal packing of 4-aminobenzonitriles and 4-amino-3,5-dimethylbenzonitriles at various temperatures
(1994)
The amino N atom in 4-aminobenzonitrile (ABN)
and 4-(dimethylamino)benzonitrile (DMABN) has a pyramidal character, with values of 34(3) and 11.9 (3) c~, respectively, for the angle between the planes of the amino group ...
Zeitschriftenartikel
Erste Kristallstruktur eines Selenans; Metall(II)-Komplexe mit dem 2,4,6-Tris(trifluormethyl)selenophenolat-Liganden
(1994)
RfSeH 1 entsteht in einer Eintopfsynthese bei der Reaktion von RfLi [Rf = 2,4,6-Tris(trifluormethyl)phenyl] mit elementarem Selen und anschließender Umsetzung mit HBF4. Mit 1 konnte zum ersten Mal die Kristallstruktur eines ...
Zeitschriftenartikel
Two Tris(imino)tin(II) and -lead(II) Cage Complexes. Syntheses and Structures of E[.mu.-N:C(tBu)Ph]3Li.cntdot.THF (E = Sn, Pb)
(1994)
The reactions of CpzPb and Cp2p. with LiN=C('Bu)Ph (1:l; 2 or 3 equiv) in THF produce the isostructural complexes Pb[p.-N=C('Bu)Ph]3Li*THF (1) and Sn[p-N=C('Bu)Ph]3Li-THF (2), respectively. Complex 2 can also be prepared ...