Items 11-20 of 30
Ryanodin-Rezeptor-Stabilisatoren. Neue Strategie zur Behandlung von Herzrhythmusstörungen und Herzinsuffizienz
Unterschiedliche Krankheitsformen wie Arrhythmie, Herzinsuffizienz, Skelettmuskelmyopathie und Epilepsie werden neuerdings mit pathologisch gesteigerter Freisetzung („Leak“) von Ca2+ aus intrazellulären Organellen assoziiert. ...
Interleukin-2 receptor antagonists for pediatric liver transplant recipients: A systematic review and meta-analysis of controlled studies.
IL-2RA are frequently used as induction therapy in liver transplant recipients to decrease the risk of AR while allowing the reduction of concomitant immunosuppression. The exact association with the use of IL-2RA, however, ...
Superresolution microscopy in heart — Cardiac nanoscopy
Detailed understanding of the adaptive nature of cardiac cells in health and disease requires investigation of proteins and membranes in their native physiological environment, ideally by noninvasive optical methods. ...
Effects of Two Guideline Implementation Strategies on Patient Outcomes in Primary Care
Study design: Cluster randomized controlled trial Objective: To improve quality of care for patients with low back pain (LBP) a multifaceted general practitioner education alone and in combination with motivational ...
Time will tell: Deficits of temporal-information processing in patients with visual field loss
Visual field loss after brain lesions is commonly determined using perimetric tests of light detection (perimetry). Many patients with visual field defects complain about perceptual difficulties in areas that are ...
Filtration of protein aggregates increases the accuracy for diagnosing prion diseases in brain biopsies.
In brain biopsies taken from patients with rapidly progressive dementia, the first differential diagnoses to be ruled out are prion diseases. For safe diagnostic processing of tissue and instruments, a rapid, highly ...
Favorable impact of the interleukin-4 receptor allelic variant I75 on the survival of diffuse large B-cell lymphoma patients demonstrated in a large prospective clinical trial.
BACKGROUND: Recently published data indicate that host germline variations in immune genes can influence the outcome of lymphoma patients. Interleukin (IL)-4 and IL13 are crucial immune factors and may influence the course ...
An antidote for calcium leak: targeting molecular arrhythmia mechanisms.
Detection of classical and atypical/Nor98 scrapie by the paraffin-embedded tissue blot method.
The paraffin-embedded tissue (PET) blot method was used to investigate sections of the central nervous system and lymphatic tissues from 24 cases of classical scrapie and 25 cases of atypical/Nor98 scrapie in sheep and ...
Hartung-Knapp-Sidik-Jonkman approach and its modification for random-effects meta-analysis with few studies
BACKGROUND: Random-effects meta-analysis is commonly performed by first deriving an estimate of the between-study variation, the heterogeneity, and subsequently using this as the basis for combining results, i.e., for ...