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Gene content evolution in the arthropods

dc.contributor.authorThomas, Gregg W C
dc.contributor.authorDohmen, Elias
dc.contributor.authorHughes, Daniel S T
dc.contributor.authorMurali, Shwetha C
dc.contributor.authorPoelchau, Monica
dc.contributor.authorGlastad, Karl
dc.contributor.authorAnstead, Clare A
dc.contributor.authorAyoub, Nadia A
dc.contributor.authorBatterham, Phillip
dc.contributor.authorBellair, Michelle
dc.contributor.authorBinford, Greta J
dc.contributor.authorChao, Hsu
dc.contributor.authorChen, Yolanda H
dc.contributor.authorChilders, Christopher
dc.contributor.authorDinh, Huyen
dc.contributor.authorDoddapaneni, Harsha V
dc.contributor.authorDuan, Jian J
dc.contributor.authorDugan, Shannon
dc.contributor.authorEsposito, Lauren A
dc.contributor.authorFriedrich, Markus
dc.contributor.authorGarb, Jessica
dc.contributor.authorGasser, Robin B
dc.contributor.authorGoodisman, Michael A D
dc.contributor.authorGundersen-Rindal, Dawn E
dc.contributor.authorHan, Yi
dc.contributor.authorHandler, Alfred M
dc.contributor.authorHatakeyama, Masatsugu
dc.contributor.authorHering, Lars
dc.contributor.authorHunter, Wayne B
dc.contributor.authorIoannidis, Panagiotis
dc.contributor.authorJayaseelan, Joy C
dc.contributor.authorKalra, Divya
dc.contributor.authorKhila, Abderrahman
dc.contributor.authorKorhonen, Pasi K
dc.contributor.authorLee, Carol E
dc.contributor.authorLee, Sandra L
dc.contributor.authorLi, Yiyuan
dc.contributor.authorLindsey, Amelia R I
dc.contributor.authorMayer, Georg
dc.contributor.authorMcGregor, Alistair P
dc.contributor.authorMcKenna, Duane D
dc.contributor.authorMisof, Bernhard
dc.contributor.authorMunidasa, Mala
dc.contributor.authorMunoz-Torres, Monica
dc.contributor.authorMuzny, Donna M
dc.contributor.authorNiehuis, Oliver
dc.contributor.authorOsuji-Lacy, Nkechinyere
dc.contributor.authorPalli, Subba R
dc.contributor.authorPanfilio, Kristen A
dc.contributor.authorPechmann, Matthias
dc.contributor.authorPerry, Trent
dc.contributor.authorPeters, Ralph S
dc.contributor.authorPoynton, Helen C
dc.contributor.authorPrpic, Nikola-Michael
dc.contributor.authorQu, Jiaxin
dc.contributor.authorRotenberg, Dorith
dc.contributor.authorSchal, Coby
dc.contributor.authorSchoville, Sean D
dc.contributor.authorScully, Erin D
dc.contributor.authorSkinner, Evette
dc.contributor.authorSloan, Daniel B
dc.contributor.authorStouthamer, Richard
dc.contributor.authorStrand, Michael R
dc.contributor.authorSzucsich, Nikolaus U
dc.contributor.authorWijeratne, Asela
dc.contributor.authorYoung, Neil D
dc.contributor.authorZattara, Eduardo E
dc.contributor.authorBenoit, Joshua B
dc.contributor.authorZdobnov, Evgeny M
dc.contributor.authorPfrender, Michael E
dc.contributor.authorHackett, Kevin J
dc.contributor.authorWerren, John H
dc.contributor.authorWorley, Kim C
dc.contributor.authorGibbs, Richard A
dc.contributor.authorChipman, Ariel D
dc.contributor.authorWaterhouse, Robert M
dc.contributor.authorBornberg-Bauer, Erich
dc.contributor.authorHahn, Matthew W
dc.contributor.authorRichards, Stephen
dc.date.accessioned2020-01-26T04:12:21Z
dc.date.available2020-01-26T04:12:21Z
dc.date.issued2020
dc.identifier.urihttp://resolver.sub.uni-goettingen.de/purl?gs-1/17144
dc.description.abstractAbstract Background Arthropods comprise the largest and most diverse phylum on Earth and play vital roles in nearly every ecosystem. Their diversity stems in part from variations on a conserved body plan, resulting from and recorded in adaptive changes in the genome. Dissection of the genomic record of sequence change enables broad questions regarding genome evolution to be addressed, even across hyper-diverse taxa within arthropods. Results Using 76 whole genome sequences representing 21 orders spanning more than 500 million years of arthropod evolution, we document changes in gene and protein domain content and provide temporal and phylogenetic context for interpreting these innovations. We identify many novel gene families that arose early in the evolution of arthropods and during the diversification of insects into modern orders. We reveal unexpected variation in patterns of DNA methylation across arthropods and examples of gene family and protein domain evolution coincident with the appearance of notable phenotypic and physiological adaptations such as flight, metamorphosis, sociality, and chemoperception. Conclusions These analyses demonstrate how large-scale comparative genomics can provide broad new insights into the genotype to phenotype map and generate testable hypotheses about the evolution of animal diversity.
dc.language.isoen
dc.publisherBioMed Central
dc.identifier.bibliographicCitationGenome Biology. 2020 Jan 23;21(1):15
dc.rightsopenAccess
dc.titleGene content evolution in the arthropods
dc.typejournalArticle
dc.identifier.doi10.1186/s13059-019-1925-7
dc.type.versionpublishedVersion
dc.date.updated2020-01-26T04:12:21Z
dc.rights.holderThe Author(s).
dc.bibliographicCitation.volume21
dc.bibliographicCitation.issue1
dc.type.subtypejournalArticle
dc.bibliographicCitation.articlenumber15
dc.bibliographicCitation.journalGenome Biology


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