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Calm Before the Storm: A Glimpse into the Secondary Metabolism of Aspergillus welwitschiae, the Etiologic Agent of the Sisal Bole Rot

dc.contributor.authorQuintanilha-Peixoto, Gabriel
dc.contributor.authorTorres, Rosimére Oliveira
dc.contributor.authorAlves Reis, Isabella Mary
dc.contributor.authorAlves Santos de Oliveira, Thiago
dc.contributor.authorBortolini, Dener Eduardo
dc.contributor.authorAlves Duarte, Elizabeth Amélia
dc.contributor.authorAriston de Carvalho Azevedo, Vasco
dc.contributor.authorBrenig, Bertram
dc.contributor.authorGuimarães Rocha Aguiar, Eric Roberto
dc.contributor.authorSoares, Ana Cristina Fermino
dc.contributor.authorGóes-Neto, Aristóteles
dc.contributor.authorBranco, Alexsandro
dc.date.accessioned2020-01-15T10:07:50Z
dc.date.available2020-01-15T10:07:50Z
dc.date.issued2019de
dc.relation.ISSN2072-6651de
dc.identifier.urihttp://resolver.sub.uni-goettingen.de/purl?gs-1/17112
dc.description.abstractAspergillus welwitschiae is a species of the Nigri section of the genus Aspergillus. In nature, it is usually a saprotroph, decomposing plant material. However, it causes the bole rot disease of Agave sisalana (sisal), a plant species used for the extraction of hard natural fibers, causing great economic loss to this culture. In this study, we isolated and sequenced one genome of A. welwitschiae (isolate CCMB 674 (Collection of Cultures of Microorganisms of Bahia)) from the stem tissues of sisal and performed in silico and wet lab experimental strategies to describe its ability to produce mycotoxins. CCMB 674 possesses 64 secondary metabolite gene clusters (SMGCs) and, under normal conditions, it produces secondary metabolism compounds that could disturb the cellular cycle of sisal or induce abnormalities in plant growth, such as malformin C. This isolate also produces a pigment that might explain the characteristic red color of the affected tissues. Additionally, this isolate is defective for the production of fumonisin B1, and, despite bearing the full cluster for the synthesis of this compound, it did not produce ochratoxin A. Altogether, these results provide new information on possible strategies used by the fungi during the sisal bole rot, helping to better understand this disease and how to control it.de
dc.language.isoengde
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectmycotoxin; phytotoxic; red rot of sisalde
dc.subject.ddc630
dc.titleCalm Before the Storm: A Glimpse into the Secondary Metabolism of Aspergillus welwitschiae, the Etiologic Agent of the Sisal Bole Rotde
dc.typejournalArticlede
dc.identifier.doi10.3390/toxins11110631
dc.type.versionpublishedVersionde
dc.relation.eISSN2072-6651
dc.bibliographicCitation.volume11de
dc.bibliographicCitation.issue11de
dc.type.subtypejournalArticle
dc.identifier.pmid31671681
dc.bibliographicCitation.articlenumber631de
dc.description.statuspeerReviewedde
dc.bibliographicCitation.journalToxinsde


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