Items 31-40 of 355
LTR12 promoter activation in a broad range of human tumor cells by HDAC inhibition.
A considerable proportion of the human genome consists of transposable elements, including the long terminal repeats (LTRs) of endogenous retroviruses. During evolution, such LTRs were occasionally inserted upstream of ...
A robust (re-)annotation approach to generate unbiased mapping references for RNA-seq-based analyses of differential expression across closely related species
Abstract Background RNA-seq based on short reads generated by next generation sequencing technologies has become the main approach to study differential gene expression. Until now, the main applications of this technique ...
The Use of Hebbian Cell Assemblies for Nonlinear Computation
When learning a complex task our nervous system self-organizes large groups of neurons into coherent dynamic activity patterns. During this, a network with multiple, simultaneously active, and computationally powerful ...
Experimental Muscle Pain Impairs the Synergistic Modular Control of Neck Muscles.
A motor task can be performed via different patterns of muscle activation that show regularities that can be factorized in combinations of a reduced number of muscle groupings (also referred to as motor modules, or muscle ...
Perspective on the combined use of an independent transgenic sexing and a multifactorial reproductive sterility system to avoid resistance development against transgenic Sterile Insect Technique approaches
Abstract Background The Sterile Insect Technique (SIT) is an accepted species-specific genetic control approach that acts as an insect birth control measure, which can be improved by biotechnological engineering to facilitate ...
Polyandry in the medfly - shifts in paternity mediated by sperm stratification and mixing
Abstract Background In the Mediterranean fruit fly (medfly), Ceratitis capitata, a highly invasive agricultural pest species, polyandry, associated with sperm precedence, is a recurrent behaviour in the wild. The absence ...
Nonlinear integration of evidence in a dynamic motor task
Reaching movements are governed by estimates of sensory and environmental quantities. If performed under uncertainty they are often based on prior expectations that summarise previous relevant information. We study the ...