1-10 von 272 Publikationen
The effect of hypoxia on the lipidome of recombinant Pichia pastoris
(BioMed Central, 2017)
Abstract Background Cultivation of recombinant Pichia pastoris (Komagataella sp.) under hypoxic conditions has a strong positive effect on specific productivity when the glycolytic GAP promoter is used for recombinant ...
The Use of Hebbian Cell Assemblies for Nonlinear Computation
When learning a complex task our nervous system self-organizes large groups of neurons into coherent dynamic activity patterns. During this, a network with multiple, simultaneously active, and computationally powerful ...
Induction and consolidation of calcium-based homo- and heterosynaptic potentiation and depression
DNA damage-induced translocation of S100A11 into the nucleus regulates cell proliferation
Background Proteins are able to react in response to distinct stress stimuli by alteration of their subcellular distribution. The stress-responsive protein S100A11 belongs to the family of multifunctional S100 proteins ...
Partial response to supra-threshold excitation desynchronizes spiking neurons
Odor supported place cell model and goal navigation in rodents
Experiments with rodents demonstrate that visual cues play an important role in the control of hippocampal place cells and spatial navigation. Nevertheless, rats may also rely on auditory, olfactory and somatosensory stimuli ...
Scale-invariance of receptive field properties in primary visual cortex
Background: Our visual system enables us to recognize visual objects across a wide range of spatial scales. The neural mechanisms underlying these abilities are still poorly understood. Size- or scale-independent representation ...
Behavioral analysis of differential hebbian learning in closed-loop systems
Understanding closed loop behavioral systems is a non-trivial problem, especially when they change during learning. Descriptions of closed loop systems in terms of information theory date back to the 1950s, however, ...
Mathematical properties of neuronal TD-rules and differential Hebbian learning: a comparison
A confusingly wide variety of temporally asymmetric learning rules exists related to reinforcement learning and/or to spike-timing dependent plasticity, many of which look exceedingly similar, while displaying strongly ...
Sperry versus Hebb: Topographic mapping in Isl2/EphA3 mutant mice
Background In wild-type mice, axons of retinal ganglion cells establish topographically precise projection to the superior colliculus of the midbrain. This means that axons of neighboring retinal ganglion cells project ...