Small-world networks interpolate between fully regular and fully random topologies and simultaneously exhibit large local clustering as well as short average path length. Smallworld topology has therefore been suggested ...

Human walking is a dynamic, partly self-stabilizing process relying on the interaction of the biomechanical design with its neuronal control. The coordination of this process is a very difficult problem, and it has been ...

Background: A major problem in pain medicine is the lack of knowledge about which treatment suits a specific patient. We tested the ability of quantitative sensory testing to predict the analgesic effect of pregabalin and ...

Complex networks of dynamically connected saddle states persistently emerge in a broad range of highdimensional systems and may reliably encode inputs as specific switching trajectories. Their computational capabilities, ...

Recently evidence has accumulated that many neural networks exhibit self-organized criticality. In this state, activity is similar across temporal scales and this is beneficial with respect to information flow. If subcritical, ...

DenA/DEN1 and the COP9 signalosome (CSN) represent two deneddylases which remove the ubiquitin-like Nedd8 from modified target proteins and are required for distinct fungal developmental programmes. The cellular DenA/DEN1 ...

Specialization in agricultural systems can lead to trade-offs between economic gains and ecosystem functions. We suggest and explore a conceptual framework in which economic gains can be maximized when production activities ...

Genetic screens are powerful tools to identify the genes required for a given biological process. However, for technical reasons, comprehensive screens have been restricted to very few model organisms. Therefore, although ...

Motorized treadmills have been widely used in locomotion studies, although a debate remains concerning the extrapolation of results obtained from treadmill experiments to overground locomotion. Slight differences between ...

Experiments were done to determine whether the starting position of the arm influences its final configuration (posture) when pointing to, or grasping, targets located within the common workspace of the arm. Subjects were ...