Items 11-20 of 185
Genetic ablation of VIAAT in glycinergic neurons causes a severe respiratory phenotype and perinatal death
Both glycinergic and GABAergic neurons require the vesicular inhibitory amino acid transporter (VIAAT) for synaptic vesicle filling. Presynaptic GABA concentrations are determined by the GABA synthesizing enzymes glutamate ...
Cytoplasmic polyadenylation element binding protein (CPEB)1 and 2 bind to the HIF-1α mRNA 3’UTR and modulate HIF-1 α protein expression
(Portland Press Limited, 2010)
The heterodimeric hypoxia-inducible factor (HIF)-1 is a transcriptional master regulator of several genes involved in mammalian oxygen homeostasis. Besides a well described regulation of the HIFα-subunit via hydroxylation-mediated ...
The path player game
We introduce the path player game, a noncooperative network game with a continuum of mutually dependent set of strategies. This game models network flows from the point of view of competing network oper- ators. The ...
Auf dem goldenen Weg? Alternative Geschäftsmodelle für Open-Access-Primärpublikationen
Publications in Open Access media are free of charge to the readers but nevertheless need to be financed. Scholars, their institutions and libraries as well as research funders contribute. This places them in a new position ...
Geographic bias of field observations of soil carbon stocks with tropical land-use changes precludes spatial extrapolation
Accurately quantifying changes in soil carbon (C) stocks with land-use change is important for estimating the anthropogenic fluxes of greenhouse gases to the atmosphere and for implementing policies such as REDD (Reducing ...
Vaccination approaches against opportunistic fungal infections caused by Aspergillus fumigatus.
Although innate immunity primarily combats systemic infections of opportunistic fungi such as Aspergillus and Candida spp., acquired and protective immunoreactions were observed long ago in animal trials following sublethal ...
Anchored Hyperplane Location Problems
The anchored hyperplane location problem is to locate a hyperplane passing through some given points P ⊆ Rn and minimizing either the sum of weighted distances (median problem), or the maximum weighted distance (center ...
Competition Horses Housed in Single Stalls (II): Effects of Free Exercise on the Behavior in the Stable, the Behavior during Training, and the Degree of Stress
Although housing horses in single stalls limits their natural behaviour to a great extent, this housing system is widespread in Germany, especially for competition horses. To improve the welfare of this system, free exercise ...
Temporary Turnout for Free Exercise in Groups: Effects on the Behavior of Competition Horses Housed in Single Stalls
In Germany most competition horses are housed in single stalls and free exercise is not permitted in many cases. The reason for not allowing free exercise is mostly the risk of injury. Additionally, opinions exist that the ...
Hard X-Ray Focusing with Curved Reflective Multilayers
This paper provides a comprehensive overview on the utilization of curved graded multilayer coatings as focusing elements for hard X-rays. It concentrates on the Kirkpatrick-Baez (KB) focusing setup that has been developed ...