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Anti-Leukemic Activity of Shikonin: Role of ERP57 in Shikonin Induced Apoptosis in Acute Myeloid Leukemia.
BACKGROUND/AIMS: ER-Stress and activation of unfolded protein response belong to the major factors involved in chemoresistance in cancer cells. In this study we investigated the effect of shikonin on the survival of acute ...
Decontamination of medical devices from pathological amyloid-β-, tau- and α-synuclein aggregates.
Measurements of underlying-event properties using neutral and charged particles in pp collisions at s√=900 GeV and s√=7 TeV with the ATLAS detector at the LHC
We present first measurements of charged and neutral particle-flow correlations in pp collisions using the ATLAS calorimeters. Data were collected in 2009 and 2010 at centre-of-mass energies of 900 GeV and 7 TeV. Events ...
Amino Acid Variation in HLA Class II Proteins Is a Major Determinant of Humoral Response to Common Viruses.
The magnitude of the human antibody response to viral antigens is highly variable. To explore the human genetic contribution to this variability, we performed genome-wide association studies of the immunoglobulin G response ...
Complex genomic rearrangements at the PLP1 locus include triplication and quadruplication.
Inverted repeats (IRs) can facilitate structural variation as crucibles of genomic rearrangement. Complex duplication-inverted triplication-duplication (DUP-TRP/INV-DUP) rearrangements that contain breakpoint junctions ...
Photoluminescence of a single quantum emitter in a strongly inhomogeneous chemical environment.
We present the results of a comprehensive photoluminescence study of defect centres in single SiO2 nanoparticles. We show that the photo-physical properties of the luminescent centres strongly resemble those of single dye ...
High-resolution polarised Raman scattering study on spin-phonon coupling in multiferroic MnWO 4
MnWO4 passes three antiferromagnetic phase transitions below the Néel temperature TN=13.5 K. One of these phases is also ferroelectric andMnWO4 is therefore referred to as multiferroic.We investigated the effect of ...
Research outcomes resulting from taxpayers’ investment in research are a common good and should be made openly available for all. According to the European Commission (EC), open access (OA) is defined as the “practice of ...
Der Wandel der Informationspraxis in Forschung und Bibliothek
Während Informationspraxis in Forschung und Bibliothek früher vom Umgang mit Literatur dominiert war, kommen heute viele neue Werkzeuge zum Einsatz. Office-Produkte, Datenbanken und Online-Plattformen verändern den Alltag ...
A Practical One-Pot Synthesis of Positron Emission Tomography (PET) Tracers via Nickel-Mediated Radiofluorination.
Recently a novel method for the preparation of (18)F-labeled arenes via oxidative [(18)F]fluorination of easily accessible and sufficiently stable nickel complexes with [(18)F]fluoride under exceptionally mild reaction ...