Author Tzvetkov, Mladen Vassilev

• 2003 | Journal Article
  ​ ​Genetic dissection of trehalose biosynthesis in Corynebacterium glutamicum: inactivation of trehalose production leads to impaired growth and an altered cell wall lipid composition​
  Tzvetkov, M. V.; Klopprogge, C.; Zelder, O. & Liebl, W.​ (2003) 
  Microbiology, 149 pp. 1659​-1673​.​ DOI: https://doi.org/10.1099/mic.0.26205-0 
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• 2004 | Conference Abstract
  ​ ​Association of NAD(P)H oxidase and MRP genetic polymorphisms with doxorubicin-induced cardiotoxicity​
  Wojnowski, L.; Schluter, G.; Vonhof, S.; Kulle, B.; Bickeboeller, H. ; Toliat, M. R. & Suk, E. K. et al.​ (2004)
  Naunyn-Schmiedeberg s Archives of Pharmacology, 369 ​45th Spring Meeting of the German-Society-for-Experimental-and-Clinical-Pharmacology-and-Toxicology​, Mainz, GERMANY.
  New york​: Springer.
  ​Details  WoS 

• 2004 | Conference Abstract
  ​ ​NAD(P)H oxidase and MRP genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity​
  Schirmer, M. A.; Wojnowski, L.; Schluter, G.; Vonhof, S.; Kulle, B.; Bickeboeller, H.   & Toliat, M. R. et al.​ (2004)
  Circulation, 110(17) pp. 807​-808. ​77th Scientific Meeting of the American-Heart-Association​, New Orleans, LA.
  Philadelphia​: Lippincott Williams & Wilkins.
  ​Details  WoS 

• 2004 | Journal Article
  ​ ​Impact of the ultrarapid metabolizer genotype of cytochrome P450 2D6 on metoprolol pharmacokinetics and pharmacodynamics​
  Kirchheiner, J.; Heesch, C.; Bauer, S.; Meisel, C.; Seringer, A.; Goldammer, M. & Tzvetkov, M. V. et al.​ (2004) 
  Clinical Pharmacology & Therapeutics, 76(4) pp. 302​-312​.​ DOI: https://doi.org/10.1016/j.clpt.2004.07.002 
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• 2005 | Journal Article
  ​ ​Impact of the CYP2D6 ultra-rapid metabolizer genotype on doxepin pharmacokinetics and serotonin in platelets​
  Kirchheiner, J.; Henckel, H. B.; Franke, L.; Meineke, I.; Tzvetkov, M. V.; Uebelhack, R. & Roots, I. et al.​ (2005) 
  Pharmacogenetics and Genomics, 15(8) pp. 579​-587​.​
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• 2005 | Conference Abstract
  ​ ​Hydrochlorothiazide and polymorphisms in the angiotensin I converting enzyme, alpha adducin and the G-protein subunit beta 3 in healthy volunteers​
  Vormfelde, S. V.; Sehrt, D.; Tzvetkov, M. V. & Brockmoeller, J.​ (2005)
  European Journal of Clinical Pharmacology, 61(9) pp. 698​-699. ​7th Annual Congress of Clinical Pharmacology​, Dresen, GERMANY.
  New york​: Springer.
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• 2005 | Conference Abstract
  ​ ​Differential sensitivity to doxorubicin-induced cardiotoxicity in two inbred mouse strains​
  Wojnowski, L.; Seifert, S.; Schmidt, A.; Kulle, B.; Brockmoeller, J.; Tzvetkov, M. V. & Hahn, H.​ (2005)
  Naunyn-Schmiedeberg s Archives of Pharmacology, 371 ​46th Spring Meeting of the Deutsche-Gesellschaft-fur-Experimentelle-und-Klinische-Pharmakologie-und Toxikologie​, Mainz, GERMANY.
  New york​: Springer.
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• 2005 | Journal Article
  ​ ​Genome-wide single-nucleotide polymorphism arrays demonstrate high fidelity of multiple displacement-based whole-genome amplification​
  Tzvetkov, M. V.; Becker, C.; Kulle, B.; Nurnberg, P.; Brockmoeller, J. & Wojnowski, L.​ (2005) 
  Electrophoresis, 26(3) pp. 710​-715​.​ DOI: https://doi.org/10.1002/elps.200410121 
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• 2006 | Journal Article
  ​ ​Topoisomerase II beta expression level correlates with doxorubicin-induced apoptosis in peripheral blood cells​
  Kersting, G.; Tzvetkov, M. V.; Huse, K.; Kulle, B.; Hafner, V.; Brockmoeller, J. & Wojnowski, L.​ (2006) 
  Naunyn-Schmiedeberg s Archives of Pharmacology, 374(1) pp. 21​-30​.​ DOI: https://doi.org/10.1007/s00210-006-0091-0 
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• 2006 | Journal Article
  ​ ​Hydrochlorothiazide efficacy and polymorphisms in ACE, ADD1 and GNB3 in healthy, male volunteers​
  Vormfelde, S. V.; Sehrt, D.; Bolte, D.; Pahl, S.; Tzvetkov, M. V. & Brockmoeller, J.​ (2006) 
  European Journal of Clinical Pharmacology, 62(3) pp. 195​-201​.​ DOI: https://doi.org/10.1007/s00228-005-0081-z 
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• 2007 | Journal Article
  ​ ​Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine​
  Tzvetkov, M. V.; Meineke, C.; Oetjen, E.; Hirsch-Ernst, K. I. & Brockmoeller, J.​ (2007) 
  Gene, 386(1-2) pp. 52​-62​.​ DOI: https://doi.org/10.1016/j.gene.2006.08.002 
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• 2007 | Journal Article
  ​ ​Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication​
  Kirchheiner, J.; Schmidt, H.; Tzvetkov, M. V.; Keulen, J.-T.; Loetsch, J.; Roots, I. & Brockmoeller, J.​ (2007) 
  The Pharmacogenomics Journal, 7(4) pp. 257​-265​.​ DOI: https://doi.org/10.1038/sj.tpj.6500406 
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• 2007 | Journal Article
  ​ ​Genetic variation in the renal sodium transporters NKCC2, NCC, and ENaC in relation to the effects of loop diuretic drugs​
  Vormfelde, S. V.; Sehrt, D.; Toliat, M. R.; Schirmer, M. A.; Meineke, I.; Tzvetkov, M. V. & Nuernberg, P. et al.​ (2007) 
  Clinical Pharmacology & Therapeutics, 82(3) pp. 300​-309​.​ DOI: https://doi.org/10.1038/sj.clpt.6100131 
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• 2008 | Conference Abstract
  ​ ​Facilitation of the protein-protein interaction between CREB and its co-activator TORC (transducer of regulated CREB) by lithium​
  Heinrich, A.; Boeer, U.; Tzvetkov, M. V. & Knepel, W.​ (2008)
  Naunyn-Schmiedeberg s Archives of Pharmacology, 377 ​49th Annual Meeting German-Society-for-Experimental-and-Clinical-Pharmacology-and-Toxicology​, Mainz, GERMANY.
  New york​: Springer.
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• 2008 | Journal Article
  ​ ​Functional characterization of a-100_-102delAAG deletion-insertion polymorphism in the promoter region of the HTR3B gene​
  Meineke, C.; Tzvetkov, M. V.; Bokelmann, K.; Oetjen, E.; Hirsch-Ernst, K. I.; Kaiser, R. & Brockmoeller, J.​ (2008) 
  Pharmacogenetics and Genomics, 18(3) pp. 219​-230​.​
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• 2008 | Journal Article
  ​ ​Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment​
  Tzvetkov, M. V.; Brockmoeller, J.; Roots, I. & Kirchheiner, J.​ (2008) 
  Pharmacogenetics and Genomics, 18(6) pp. 495​-506​.​
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• 2008 | Journal Article
  ​ ​A peroxisome proliferator-activated receptor gamma-retinoid X receptor heterodimer physically interacts with the transcriptional activator PAX6 to inhibit glucagon gene transcription​
  Kraetzner, R.; Froehlich, F.; Lepler, K.; Schroeder, M.; Roeher, K.; Dickel, C. & Tzvetkov, M. V. et al.​ (2008) 
  Molecular Pharmacology, 73(2) pp. 509​-517​.​ DOI: https://doi.org/10.1124/mol.107.035568 
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• 2008 | Journal Article
  ​ ​Phytate utilization by genetically engineered lysine-producing Corynebacterium glutamicum​
  Tzvetkov, M. V. & Liebl, W.​ (2008) 
  Journal of Biotechnology, 134(3-4) pp. 211​-217​.​ DOI: https://doi.org/10.1016/j.jbiotec.2008.02.005 
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• 2008 | Journal Article
  ​ ​Genetic polymorphisms of NAD(P)H oxidase: variation in subunit expression and enzyme activity​
  Schirmer, M. A.; Hoffmann, M.; Kaya, E.; Tzvetkov, M. V. & Brockmoeller, J.​ (2008) 
  The Pharmacogenomics Journal, 8(4) pp. 297​-304​.​ DOI: https://doi.org/10.1038/sj.tpj.6500467 
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• 2008 | Review | 
  ​ ​Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment​
  Brockmoeller, J.& Tzvetkov, M. V.​ (2008)
  European Journal of Clinical Pharmacology, 64​(2) pp. 133​-157​.​
  Heidelberg​: Springer. DOI: https://doi.org/10.1007/s00228-007-0424-z 
  ​Details  DOI  PMID  PMC  WoS 

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