Author Spitzner, Melanie
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2008 | Conference Abstract
RNAi-based identification of potential targets in colorectal cancers
Grade, M.; Hummon, A. B.; Camps, J.; Emons, G.; Spitzner, M.; Gaedcke, J. & Difilippantonio, M. J. et al. (2008)
EJC SUPPLEMENTS, 6(12) 20th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Geneva, SWITZERLAND.
Oxford: Pergamon-elsevier Science Ltd. DOI: https://doi.org/10.1016/S1359-6349(08)72485-6
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2010 | Conference Abstract
Silencing of TCF7L2 sensitizes colorectal cancer cells to radiation therapy
Grade, M.; Kendziorra, E.; Ahlborn, K.; Spitzner, M.; Gaedcke, J.; Rave-Fraenk, M. & Becker, H. et al. (2010)
EJC SUPPLEMENTS, 8(7) 22nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Berlin, GERMANY.
Oxford: Pergamon-elsevier Science Ltd. DOI: https://doi.org/10.1016/S1359-6349(10)72008-5
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2013 | Conference Paper
Targeting STAT3in vitroandin vivoreveals a novel therapeutic strategy to sensitize colorectal cancer cells to chemoradiotherapy
Spitzner, M.; Roesler, B.; Bielfeld, C.; Herzberg, C.; Emons, G.; Gaedcke, J. & Rave-Fränk, M. et al. (2013)
Cancer Research, 73(8, Suppl.) pp. 68-68. 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC. DOI: https://doi.org/10.1158/1538-7445.AM2013-68
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2014 | Review |
STAT3: A Novel Molecular Mediator of Resistance to Chemoradiotherapy
Spitzner, M.; Ebner, R.; Wolff, H. A.; Ghadimi, B. M.; Wienands, J. & Grade, M. (2014)
CANCERS, 6(4) pp. 1986-2011.
Mdpi Ag. DOI: https://doi.org/10.3390/cancers6041986
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2016 | Journal Article
Histone Chaperone SSRP1 is Essential for Wnt Signaling Pathway Activity During Osteoblast Differentiation
Hossan, T.; Nagarajan, S.; Baumgart, S. J.; Xie, W. ; Magallanes, R. T.; Hernandez, C. & Chiaroni, P.-M. et al. (2016)
Stem Cells, 34(5) pp. 1369-1376. DOI: https://doi.org/10.1002/stem.2287
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2019 | Journal Article |
The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness
Kari, V.; Raul, S. K; Henck, J. M; Kitz, J.; Kramer, F.; Kosinsky, R. L & Übelmesser, N. et al. (2019)
Clinical Epigenetics, 11(1) art. 4. DOI: https://doi.org/10.1186/s13148-018-0601-1
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2019 | Journal Article |
Combined targeting of HER-2 and HER-3 represents a promising therapeutic strategy in colorectal cancer
Conradi, L.-C.; Spitzner, M.; Metzger, A.-L.; Kisly, M.; Middel, P.; Bohnenberger, H. & Gaedcke, J. et al. (2019)
BMC Cancer, 19(1) pp. 880. DOI: https://doi.org/10.1186/s12885-019-6051-0
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2021 | Journal Article | Research Paper |
Inhibition of Wnt/β-Catenin Signaling Sensitizes Esophageal Cancer Cells to Chemoradiotherapy
Spitzner, M.; Emons, G.; Schütz, K. B.; Wolff, H. A.; Rieken, S.; Ghadimi, B. M. & Schneider, G. et al. (2021)
International Journal of Molecular Sciences, 22(19) pp. 10301. DOI: https://doi.org/10.3390/ijms221910301
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2022 | Journal Article | Research Paper |
Targeting STAT3 Signaling Facilitates Responsiveness of Pancreatic Cancer Cells to Chemoradiotherapy
Flebbe, H.; Spitzner, M.; Marquet, P. E.; Gaedcke, J.; Ghadimi, B. M.; Rieken, S. & Schneider, G. et al. (2022)
Cancers, 14(5) pp. 1301. DOI: https://doi.org/10.3390/cancers14051301
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2023 | Journal Article
Hepatic arterial infusion with nanoliposomal irinotecan leads to significant regression of tumor size of colorectal liver metastases in a CC531 rat model
Kauffels, A.; Nowack, H.; Bohnenberger, H.; Spitzner, M.; Sprenger, T.; Ghadimi, M. & Sperling, J. (2023)
Clinical & Experimental Metastasis,. DOI: https://doi.org/10.1007/s10585-023-10209-7
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