Author Spang, Rainer

1 to 20 of 43 Items
  • 2006 | Journal Article
    ​ ​A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling​
    Hummel, M.; Bentink, S.; Berger, H.; Klapper, W.; Wessendorf, S.; Barth, T. F. E. & Bernd, H. W. et al.​ (2006) 
    New England Journal of Medicine, 354(23) pp. 2419​-2430​.​ DOI: https://doi.org/10.1056/NEJMoa055351 
    ​Details  DOI  PMID  PMC  WoS 
  • 2008 | Conference Abstract
    ​ ​Conserved oncogenic module activation patterns (COMAPS) identify biologically homogeneous groups of diffuse large B-cell lymphomas and clearly define Burkitt lymphoma​
    Bentink, S.; Wessendorf, S.; Schwaenen, C.; Rosolowski, M.; Klapper, W.; Rosenwald, A. & Ott, G. et al.​ (2008)
    Annals of Oncology, 19 ​10th International Conference on Malignant Lymphoma​, Lugano, SWITZERLAND.
    Oxford​: Oxford Univ Press.
    ​Details  WoS 
  • 2008 | Conference Abstract
    ​ ​Different subtypes of aggressive B cell lymphomas share an epigenetic signature enriched for polycomb targets in stem cells​
    Martin-Subero, J. I.; Kreuz, M.; Bibikova, M.; Bentink, S.; Klapper, W.; Wickham-Garcia, E. & Rosolowski, M. et al.​ (2008)
    Annals of Oncology, 19 ​10th International Conference on Malignant Lymphoma​, Lugano, SWITZERLAND.
    Oxford​: Oxford Univ Press.
    ​Details  WoS 
  • 2008 | Journal Article
    ​ ​Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma​
    Dierlamm, J.; Penas, E. M. M.; Bentink, S.; Wessendorf, S.; Berger, H.; Hummel, M. & Klapper, W. et al.​ (2008) 
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 93(5) pp. 688​-696​.​ DOI: https://doi.org/10.3324/haematol.12057 
    ​Details  DOI  PMID  PMC  WoS 
  • 2008 | Journal Article
    ​ ​Pathway activation patterns in diffuse large B-cell lymphomas​
    Bentink, S.; Wessendorf, S.; Schwaenen, C.; Rosolowski, M.; Klapper, W.; Rosenwald, A. & Ott, G. et al.​ (2008) 
    Leukemia, 22(9) pp. 1746​-1754​.​ DOI: https://doi.org/10.1038/leu.2008.166 
    ​Details  DOI  PMID  PMC  WoS 
  • 2008 | Journal Article
    ​ ​Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials​
    Klapper, W.; Szczepanowski, M.; Burkhardt, B.; Berger, H.; Rosolowski, M.; Bentink, S. & Schwaenen, C. et al.​ (2008) 
    Blood, 112(4) pp. 1374​-1381​.​ DOI: https://doi.org/10.1182/blood-2008-01-136465 
    ​Details  DOI  PMID  PMC  WoS 
  • 2008 | Journal Article
    ​ ​Analyzing gene perturbation screens with nested effects models in R and bioconductor​
    Fröhlich, H.; Beißbarth, T. ; Tresch, A.; Kostka, D.; Jacob, J.; Spang, R. & Markowetz, F.​ (2008) 
    Bioinformatics, 24(21) pp. 2549​-2550​.​ DOI: https://doi.org/10.1093/bioinformatics/btn446 
    ​Details  DOI  PMID  PMC 
  • 2009 | Journal Article
    ​ ​Microarray-Based Genomic Profiling Reveals Novel Genomic Aberrations in Follicular War Lymphoma Which Associate with Patient Survival and Gene Expression Status​
    Schwaenen, C.; Viardot, A.; Berger, H.; Barth, T. F. E.; Bentink, S.; Doehner, H. & Enz, M. et al.​ (2009) 
    Genes Chromosomes and Cancer, 48(1) pp. 39​-54​.​ DOI: https://doi.org/10.1002/gcc.20617 
    ​Details  DOI  PMID  PMC  WoS 
  • 2009 | Journal Article
    ​ ​New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling​
    Martin-Subero, J. I.; Kreuz, M.; Bibikova, M.; Bentink, S.; Ammerpohl, O.; Wickham-Garcia, E. & Rosolowski, M. et al.​ (2009) 
    Blood, 113(11) pp. 2488​-2497​.​ DOI: https://doi.org/10.1182/blood-2008-04-152900 
    ​Details  DOI  PMID  PMC  WoS 
  • 2010 | Conference Abstract
    ​ ​A c-Myc induced gene expression signature in human germinal center B cells predicts subtypes of aggressive non-Hodgkin Lymphoma​
    Schrader, A.; Bentink, S.; Spang, R.; Lenze, D.; Hummel, M.; Kuo, M. & Murray, P. et al.​ (2010)
    EJC SUPPLEMENTS, 8(5) ​21st Meeting of the European-Association-for-Cancer-Research​, Oslo, NORWAY.
    Oxford​: Pergamon-elsevier Science Ltd.
    ​Details  WoS 
  • 2010 | Journal Article | 
    ​ ​Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis​
    Scholtysik, R.; Kreuz, M.; Klapper, W.; Burkhardt, B.; Feller, A. C.; Hummel, M. & Loeffler, M. et al.​ (2010) 
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 95(12) pp. 2047​-2055​.​ DOI: https://doi.org/10.3324/haematol.2010.026831 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults​
    Salaverria, I.; Philipp, C.; Oschlies, I.; Kohler, C. W.; Kreuz, M.; Szczepanowski, M. & Burkhardt, B. et al.​ (2011) 
    Blood, 118(1) pp. 139​-147​.​ DOI: https://doi.org/10.1182/blood-2011-01-330795 
    ​Details  DOI  PMID  PMC  WoS 
  • 2011 | Journal Article
    ​ ​Genomic data integration using guided clustering​
    Maneck, M.; Schrader, A.; Kube, D. & Spang, R.​ (2011) 
    Bioinformatics, 27(16) pp. 2231​-2238​.​ DOI: https://doi.org/10.1093/bioinformatics/btr363 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Conference Abstract
    ​ ​SOCS1 Mutation Subtypes Predict Divergent Outcomes in DLBCL Patients​
    Lennerz, J. K.; Schif, B.; Kohler, C. W.; Bentink, S.; Kreuz, M.; Melzner, I. & Truemper, L. H. et al.​ (2012)
    Blood, 120(21) ​54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)​, Atlanta, GA.
    Washington​: Amer Soc Hematology.
    ​Details  WoS 
  • 2012 | Journal Article
    ​ ​Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing​
    Richter, J.; Schlesner, M.; Hoffmann, S.; Kreuz, M.; Leich, E.; Burkhardt, B. & Rosolowski, M. et al.​ (2012) 
    Nature Genetics, 44(12) pp. 1316​-1320​.​ DOI: https://doi.org/10.1038/ng.2469 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​T cells become licensed in the lung to enter the central nervous system​
    Odoardi, F. ; Sie, C.; Streyl, K.; Ulaganathan, V. K.; Schlaeger, C.; Lodygin, D. & Heckelsmiller, K. et al.​ (2012) 
    Nature, 488(7413) pp. 675​.​ DOI: https://doi.org/10.1038/nature11337 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​High myc activity is an independent negative prognostic factor for diffuse large B cell lymphomas​
    Schrader, A.; Bentink, S.; Spang, R.; Lenze, D.; Hummel, M.; Kuo, M. & Arrand, J. R. et al.​ (2012) 
    International Journal of Cancer, 131(4) pp. E348​-E361​.​ DOI: https://doi.org/10.1002/ijc.26423 
    ​Details  DOI  PMID  PMC  WoS 
  • 2012 | Journal Article
    ​ ​Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma​
    Klapper, W.; Kreuz, M.; Kohler, C. W.; Burkhardt, B.; Szczepanowski, M.; Salaverria, I. & Hummel, M. et al.​ (2012) 
    Blood, 119(8) pp. 1882​-1887​.​ DOI: https://doi.org/10.1182/blood-2011-10-388470 
    ​Details  DOI  PMID  PMC  WoS 
  • 2013 | Journal Article | 
    ​ ​SOCS1 mutation subtypes predict divergent outcomes in diffuse large B-Cell lymphoma (DLBCL) patients.​
    Schif, B.; Lennerz, J. K.; Kohler, C. W.; Bentink, S.; Kreuz, M.; Melzner, I. & Ritz, O. et al.​ (2013) 
    Oncotarget, 4(1) pp. 35​-47​.​
    ​Details  PMID  PMC 
  • 2014 | Journal Article
    ​ ​A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma​
    Salaverria, I.; Martin-Guerrero, I.; Wagener, R.; Kreuz, M.; Kohler, C. W.; Richter, J. & Pienkowska-Grela, B. et al.​ (2014) 
    Blood, 123(8) pp. 1187​-1198​.​ DOI: https://doi.org/10.1182/blood-2013-06-507996 
    ​Details  DOI  PMID  PMC  WoS 

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