Author Siveke, Jens T.

• 2005 | Journal Article
  ​ ​SUMO modification of the ubiquitin-conjugating enzyme E2-25K​
  Pichler, A.; Knipscheer, P.; Oberhofer, E.; van Dijk, W. J.; Korner, R.; Olsen, J. V. & Jentsch, S. et al.​ (2005) 
  Nature Structural & Molecular Biology, 12(3) pp. 264​-269​.​ DOI: https://doi.org/10.1038/nsmb903 
  ​Details  DOI  PMID  PMC  WoS 

• 2014 | Journal Article
  ​ ​Inflammation-Induced NFATc1-STAT3 Transcription Complex Promotes Pancreatic Cancer Initiation by Kras(G12D)​
  Baumgart, S.; Chen, N.-M. ; Siveke, J. T.; Koenig, A. O. ; Zhang, J.; Singh, S. K. & Wolf, E. et al.​ (2014) 
  Cancer Discovery, 4(6) pp. 688​-701​.​ DOI: https://doi.org/10.1158/2159-8290.CD-13-0593 
  ​Details  DOI  PMID  PMC  WoS 

• 2015 | Journal Article
  ​ ​Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma​
  Mazur, P. K.; Herner, A.; Mello, S. S.; Wirth, M.; Hausmann, S.; Sanchez-Rivera, F. J. & Lofgren, S. M. et al.​ (2015) 
  Nature Medicine, 21(10) pp. 1163​-+​.​ DOI: https://doi.org/10.1038/nm.3952 
  ​Details  DOI  PMID  PMC  WoS 

• 2015 | Journal Article
  ​ ​Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity​
  Singh, S. K.; Chen, N.-M. ; Heßmann, E. ; Siveke, J. T.; Lahmann, M.; Singh, G. & Voelker, N. et al.​ (2015) 
  The EMBO Journal, 34(4) pp. 517​-530​.​ DOI: https://doi.org/10.15252/embj.201489574 
  ​Details  DOI  PMID  PMC  WoS 

• 2015 | Journal Article
  ​ ​NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar-Ductal Transdifferentiation in the Pancreas​
  Chen, N.-M.; Singh, G.; Koenig, A. O.; Liou, G.-Y.; Storz, P.; Zhang, J. & Regul, L. et al.​ (2015) 
  Gastroenterology, 148(5) pp. 1024​-U502​.​ DOI: https://doi.org/10.1053/j.gastro.2015.01.033 
  ​Details  DOI  PMID  PMC  WoS 

• 2016 | Review
  ​ ​MYC in pancreatic cancer: novel mechanistic insights and their translation into therapeutic strategies​
  Hessmann, E. ; Schneider, G.; Ellenrieder, V.& Siveke, J. T.​ (2016)
  Oncogene, 35​(13) pp. 1609​-1618​.​
  Nature Publishing Group. DOI: https://doi.org/10.1038/onc.2015.216 
  ​Details  DOI  PMID  PMC  WoS 

• 2017 | Journal Article | 
  ​ ​Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4-and MYC-dependent manner​
  Mishra, V. K.; Wegwitz, F.; Kosinsky, R. L.; Sen, M. ; Baumgartner, R.; Wulff, T. & Siveke, J. T. et al.​ (2017) 
  Nucleic Acids Research, 45(11) pp. 6334​-6349​.​ DOI: https://doi.org/10.1093/nar/gkx212 
  ​Details  DOI  WoS 

• 2017 | Journal Article
  ​ ​Epigenetic treatment of pancreatic cancer: is there a therapeutic perspective on the horizon?​
  Hessmann, E. ; Johnsen, S. A.; Siveke, J. T. & Ellenrieder, V.​ (2017) 
  Gut, 66(1) pp. 168​-179​.​ DOI: https://doi.org/10.1136/gutjnl-2016-312539 
  ​Details  DOI  PMID  PMC  WoS 

• 2017 | Journal Article
  ​ ​Context-Dependent Epigenetic Regulation of Nuclear Factor of Activated T Cells 1 in Pancreatic Plasticity​
  Chen, N.-M. ; Neeße, A. ; Dyck, M. L.; Steuber, B. ; König, A. O. ; Lubeseder-Martellato, C. & Winter, T. et al.​ (2017) 
  Gastroenterology, 152(6) pp. 1507​-+​.​ DOI: https://doi.org/10.1053/j.gastro.2017.01.043 
  ​Details  DOI  PMID  PMC  WoS 

• 2020 | Journal Article
  ​ ​Characterization of a dual BET / HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma​
  Zhang, X.; Zegar, T.; Weiser, T.; Hamdan, F. H.; Berger, B.; Lucas, R. & Balourdas, D. et al.​ (2020) 
  International Journal of Cancer, 147(10) pp. 2847​-2861​.​ DOI: https://doi.org/10.1002/ijc.33137 
  ​Details  DOI 

• 2024 | Journal Article
  ​ ​Pancreatic cancer acquires resistance to MAPK pathway inhibition by clonal expansion and adaptive DNA hypermethylation​
  Godfrey, L. K.; Forster, J.; Liffers, S.-T.; Schröder, C.; Köster, J.; Henschel, L. & Ludwig, K. U. et al.​ (2024) 
  Clinical Epigenetics, 16(1).​ DOI: https://doi.org/10.1186/s13148-024-01623-z 
  ​Details  DOI 

Researcher

Sort

Items per Page