Author Schulz-Heddergott, Ramona

1 to 8 of 8 Items
  • 2017 | Journal Article | 
    ​ ​Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells​
    Kramer, D.; Stark, N. ; Schulz-Heddergott, R.; Erytch, N.; Edmunds, S.; Rossmann, L.   & Bastians, H. et al.​ (2017) 
    Cell Death and Differentiation, 24(2) pp. 300​-316​.​ DOI: https://doi.org/10.1038/cdd.2016.124 
    ​Details  DOI  PMID  PMC  WoS 
  • 2017 | Journal Article | 
    ​ ​p53 loss-of-heterozygosity is a necessary prerequisite for mutant p53 stabilization and gain-of-function in vivo​
    Alexandrova, E. M.; Mirza, S. A.; Xu, S.; Schulz-Heddergott, R.; Marchenko, N. D. & Moll, U. M.​ (2017) 
    Cell Death and Disease, 8 art. e2661​.​ DOI: https://doi.org/10.1038/cddis.2017.80 
    ​Details  DOI  PMID  PMC  WoS 
  • 2018 | Journal Article | 
    ​ ​Gain-of-Function (GOF) Mutant p53 as Actionable Therapeutic Target​
    Schulz-Heddergott, R. & Moll, U. M.​ (2018) 
    Cancers, 10(6).​ DOI: https://doi.org/10.3390/cancers10060188 
    ​Details  DOI  PMID  PMC 
  • 2019 | Journal Article
    ​ ​Transformation Mechanisms of the Nfia-ETO2 Fusion Gene Associated with Pediatric Pure Acute Erythroleukemia​
    Piqué-Borràs, M.-R.; Bagger, F. O.; Bezerra, M. F.; Louwaige, A.; Juge, S.; Nellas, I. & Ivanek, R. et al.​ (2019) 
    Blood, 134(Supplement_1) pp. 532​-532​.​ DOI: https://doi.org/10.1182/blood-2019-126416 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Hsp90-stabilized MIF supports tumor progression via macrophage recruitment and angiogenesis in colorectal cancer​
    Klemke, L.; De Oliveira, T.; Witt, D.; Winkler, N.; Bohnenberger, H.; Bucala, R. & Conradi, L.-C. et al.​ (2021) 
    Cell Death & Disease, 12(2).​ DOI: https://doi.org/10.1038/s41419-021-03426-z 
    ​Details  DOI 
  • 2021 | Journal Article | Research Paper | 
    ​ ​Suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity​
    Isermann, T.; Şener, Ö. Ç.; Stender, A.; Klemke, L.; Winkler, N.; Neesse, A. & Li, J. et al.​ (2021) 
    Nature Communications, 12(1) art. 4019​.​ DOI: https://doi.org/10.1038/s41467-021-24064-1 
    ​Details  DOI 
  • 2023 | Journal Article
    ​ ​CDK4/6 inhibition confers protection of normal gut epithelia against gemcitabine and the active metabolite of irinotecan​
    Blume, J.; Claus, L.; Isermann, T.; Dickmanns, A.; Conradi, L.-C.; Schulz-Heddergott, R. & Dobbelstein, M.​ (2023) 
    Cell Cycle, pp. 1​-20​.​ DOI: https://doi.org/10.1080/15384101.2023.2217003 
    ​Details  DOI 
  • 2024 | Preprint
    ​ ​Enhancement of colorectal cancer therapy through interruption of the HSF1-HSP90 axis by p53 activation or cell cycle inhibition​
    Isermann, T.; Schneider, K. L.; Wegwitz, F.; De Oliveira, T.; Conradi, L.-C.; Volk, V.& Feuerhake, F. et al.​ (2024). DOI: https://doi.org/10.1101/2024.02.22.581507 
    ​Details  DOI 

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