Author Schuberth, Ingrid
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2000 | Journal Article
Preparation of a new carboranyl lactoside for the treatment of cancer by boron neutron capture therapy: Synthesis and toxicity of fluoro carboranyl glycosides for in vivo F-19-NMR spectroscopy
Tietze, L. F. ; Bothe, U. & Schuberth, I. (2000)
Chemistry - A European Journal, 6(5) pp. 836-842. DOI: https://doi.org/10.1002/(SICI)1521-3765(20000303)6:5<836::AID-CHEM836>3.0.CO;2-8
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2003 | Journal Article
Novel Carboranyl C-Glycosides for the Treatment of Cancer by Boron Neutron Capture Therapy.
Tietze, L. F.; Griesbach, U.; Schuberth, I.; Bothe, U.; Marra, A. & Dondoni, A. (2003)
ChemInform, 34(28). DOI: https://doi.org/10.1002/chin.200328212
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2005 | Journal Article
A Diels—Alder Reaction for the Total Synthesis of the Novel Antibiotic Antitumor Agent Mensacarcin (I).
Tietze, L. F.; Guentner, C.; Gericke, K. M.; Schuberth, I. & Bunkoczi, G. (2005)
ChemInform, 36(43). DOI: https://doi.org/10.1002/chin.200543222
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2006 | Journal Article
Investigation of reactivity and selectivity of DNA-alkylating duocarmycin analogues by high-resolution mass spectrometry
Tietze, L. F.; Krewer, B.; Frauendorf, H.; Major, F. & Schuberth, I. (2006)
Angewandte Chemie International Edition, 45(39) pp. 6570-6574. DOI: https://doi.org/10.1002/anie.200600935
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2006 | Journal Article
Antitumor agents: Development of highly potent glycosidic duocarmycin analogues for selective cancer therapy
Tietze, L. F.; Major, F. & Schuberth, I. (2006)
Angewandte Chemie International Edition, 45(39) pp. 6574-6577. DOI: https://doi.org/10.1002/anie.200600936
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2007 | Journal Article
Synthesis of highly functionalized anthraquinones and evaluation of their antitumor activity
Tietze, L. F.; Gericke, K. M. & Schuberth, I. (2007)
European Journal of Organic Chemistry,(27) pp. 4563-4577. DOI: https://doi.org/10.1002/ejoc.200700418
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2007 | Journal Article
Novel strategies for the synthesis of anthrapyran antibiotics: discovery of a new antitumor agent and total synthesis of (S)-espicufolin
Tietze, L. F.; Gericke, K. M.; Singidi, R. R. & Schuberth, I. (2007)
Organic & Biomolecular Chemistry, 5(8) pp. 1191-1200. DOI: https://doi.org/10.1039/b700838d
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2007 | Journal Article
Selective treatment of cancer: Synthesis, biological evaluation and structural elucidation of novel analogues of the antibiotic CC-1065 and the duocarmycins
Tietze, L. F.; Major, F.; Schuberth, I.; Spiegl, D. A.; Krewer, B.; Maksimenka, K. & Bringmann, G. et al. (2007)
Chemistry - A European Journal, 13(16) pp. 4396-4409. DOI: https://doi.org/10.1002/chem.200700113
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2008 | Journal Article |
Synthesis and biological evaluation of a novel pentagastrin-toxin conjugate designed for a targeted prodrug monotherapy of cancer
Tietze, L. F.; Panknin, O.; Krewer, B.; Major, F. & Schuberth, I. (2008)
International Journal of Molecular Sciences, 9(5) pp. 821-837. DOI: https://doi.org/10.3390/ijms9050821
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2008 | Journal Article
Duocarmycin-based prodrugs for cancer prodrug monotherapy
Tietze, L. F.; Schuster, H. J.; Schmuck, K.; Schuberth, I. & Alves, F. (2008)
Bioorganic & Medicinal Chemistry, 16(12) pp. 6312-6318. DOI: https://doi.org/10.1016/j.bmc.2008.05.009
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2008 | Journal Article
Asymmetric Synthesis and Biological Evaluation of Glycosidic Prodrugs for a Selective Cancer Therapy
Tietze, L. F.; von Hof, J. M.; Krewer, B.; Mueller, M.; Major, F.; Schuster, H. J. & Schuberth, I. et al. (2008)
ChemMedChem, 3(12) pp. 1946-1955. DOI: https://doi.org/10.1002/cmdc.200800250
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2009 | Journal Article |
A comprehensive view on 4-methyl-2-quinazolinamine, a new microbial alkaloid from Streptomyces of TCM plant origin
Vollmar, D.; Thorn, A.; Schuberth, I. & Grond, S. (2009)
The Journal of Antibiotics, 62(8) pp. 439-444. DOI: https://doi.org/10.1038/ja.2009.68
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2009 | Journal Article
CD-Spectroscopy As a Powerful Tool for Investigating the Mode of Action of Unmodified Drugs in Live Cells
Tietze, L. F.; Krewer, B.; Major, F. & Schuberth, I. (2009)
Journal of the American Chemical Society, 131(36) pp. 13031-13036. DOI: https://doi.org/10.1021/ja902767f
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2009 | Journal Article
Synthesis and Biological Studies of Different Duocarmycin Based Glycosidic Prodrugs for Their Use in the Antibody-Directed Enzyme Prodrug Therapy
Tietze, L. F.; Schuster, H. J.; Krewer, B. & Schuberth, I. (2009)
Journal of Medicinal Chemistry, 52(2) pp. 537-543. DOI: https://doi.org/10.1021/jm8009102
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2009 | Journal Article |
Determination of the Biological Activity and Structure Activity Relationships of Drugs Based on the Highly Cytotoxic Duocarmycins and CC-1065
Tietze, L. F.; Krewer, B.; von Hof, J. M.; Frauendorf, H. & Schuberth, I. (2009)
Toxins, 1(2) pp. 134-150. DOI: https://doi.org/10.3390/toxins1020134
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2010 | Journal Article
ChemInform Abstract: Highly Selective Glycosylated Prodrugs of Cytostatic CC-1065 Analogues for Antibody-Directed Enzyme Tumor Therapy.
Tietze, L. F.; Herzig, T.; Fecher Anja, F. A.; Haunert, F. & Schuberth, I. (2010)
ChemInform, 33(4) pp. no-no. DOI: https://doi.org/10.1002/chin.200204251
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2010 | Journal Article
ChemInform Abstract: A Comprehensive View on 4-Methyl-2-quinazolinamine, a New Microbial Alkaloid from Streptomyces of TCM Plant Origin.
Volmar, D.; Thorn, A.; Schuberth, I. & Grond, S. (2010)
ChemInform, 41(1) pp. no-no. DOI: https://doi.org/10.1002/chin.201001204
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2010 | Journal Article
Synthesis of the first spacer containing prodrug of a duocarmycin analogue and determination of its biological activity
Schuster, H. J.; Krewer, B.; von Hof, J. M.; Schmuck, K.; Schuberth, I.; Alves, F. & Tietze, L. F. (2010)
Organic & Biomolecular Chemistry, 8(8) pp. 1833-1842. DOI: https://doi.org/10.1039/b925070k
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2010 | Journal Article
Glycosidic Prodrugs of Highly Potent Bifunctional Duocarmycin Derivatives for Selective Treatment of Cancer
Tietze, L. F. ; von Hof, J. M.; Mueller, M.; Krewer, B. & Schuberth, I. (2010)
Angewandte Chemie International Edition, 49(40) pp. 7336-7339. DOI: https://doi.org/10.1002/anie.201002502
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2011 | Journal Article
Synthesis and Biological Evaluation of Prodrugs Based on the Natural Antibiotic Duocarmycin for Use in ADEPT and PMT
Tietze, L. F.; Schmuck, K.; Schuster, H. J.; Mueller, M. & Schuberth, I. (2011)
Chemistry - A European Journal, 17(6) pp. 1922-1929. DOI: https://doi.org/10.1002/chem.201002798
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