Author Schildhaus, Hans-Ulrich

• 2013 | Journal Article | 
  ​ ​Chromogenic in situ hybridization is a reliable assay for detection of ALK rearrangements in adenocarcinomas of the lung​
  Schildhaus, H.-U.; Deml, K.-F.; Schmitz, K.; Meiboom, M.; Binot, E.; Hauke, S. & Merkelbach-Bruse, S. et al.​ (2013) 
  Modern Pathology, 26(11) pp. 1468​-1477​.​ DOI: https://doi.org/10.1038/modpathol.2013.95 
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• 2014 | Conference Abstract
  ​ ​TRY: A phase II study to evaluate safety and efficacy of combined trastuzumab and AUY922 in advanced non-small cell lung cancer (NSCLC) with HER2 overexpression or amplification or mutation.​
  Nogova, L.; Gardizi, M.; Christiaan, M.; Bos, A.; Scheffler, M.; Mattonet, C. & Heukamp, L. C. et al.​ (2014)
  Journal of Clinical Oncology, 32(15) ​50th Annual Meeting of the American-Society-of-Clinical-Oncology​, Chicago, IL.
  Alexandria​: Amer Soc Clinical Oncology.
  ​Details  WoS 

• 2014 | Journal Article | 
  ​ ​Squamous Cell Carcinoma of the Pancreas in a Patient with Germline BRCA2 Mutation-Response to Neoadjuvant Radiochemotherapy.​
  Schultheis, A. M.; Nguyen, G. P.; Ortmann, M.; Kruis, W.; Büttner, R.; Schildhaus, H.-U. & Markiefka, B.​ (2014) 
  Case reports in oncological medicine, 2014 art. 860532​.​ DOI: https://doi.org/10.1155/2014/860532 
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• 2014 | Journal Article | 
  ​ ​Fibroblast growth factor receptor 1 (FGFR1) amplification is a potential therapeutic target in small-cell lung cancer​
  Schultheis, A. M.; Bos, M.; Schmitz, K.; Wilsberg, L.; Binot, E.; Wolf, J. & Buettner, R. et al.​ (2014) 
  Modern Pathology, 27(2) pp. 214​-221​.​ DOI: https://doi.org/10.1038/modpathol.2013.141 
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• 2014 | Journal Article
  ​ ​High-resolution melting analysis is a sensitive diagnostic tool to detect imatinib-resistant and imatinib-sensitive PDGFRA exon 18 mutations in gastrointestinal stromal tumors​
  Kuenstlinger, H.; Binot, E.; Merkelbach-Bruse, S.; Huss, S.; Wardelmann, E.; Buettner, R. & Schildhaus, H.-U.​ (2014) 
  Human Pathology, 45(3) pp. 573​-582​.​ DOI: https://doi.org/10.1016/j.humpath.2013.10.025 
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• 2014 | Journal Article | 
  ​ ​Comparison of high resolution melting analysis, pyrosequencing, next generation sequencing and immunohistochemistry to conventional Sanger sequencing for the detection of p.V600E and non-p.V600E BRAF mutations​
  Ihle, M. A.; Fassunke, J.; König, K.; Grünewald, I.; Schlaak, M.; Kreuzberg, N. & Tietze, L. et al.​ (2014) 
  BMC Cancer, 14(1) art. 13​.​ DOI: https://doi.org/10.1186/1471-2407-14-13 
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• 2014 | Journal Article | 
  ​ ​Challenging dedifferentiated liposarcoma identified by MDM2-amplification, a report of two cases​
  Lokka, S.; Scheel, A. H.; Dango, S.; Schmitz, K.; Hesterberg, R.; Rüschoff, J. & Schildhaus, H.-U.​ (2014) 
  BMC Clinical Pathology, 14(1) art. 36​.​ DOI: https://doi.org/10.1186/1472-6890-14-36 
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• 2014 | Journal Article
  ​ ​Rhabdoid morphology in gastrointestinal stromal tumours (GISTs) is associated with PDGFRA mutations but does not imply aggressive behaviour​
  Schaefer, I.-M.; Stroebel, P.; Cameron, S.; Beham, A. W.; Otto, C.; Schildhaus, H.-U. & Agaimy, A.​ (2014) 
  Histopathology, 64(3) pp. 421​-430​.​ DOI: https://doi.org/10.1111/his.12265 
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• 2014 | Journal Article
  ​ ​Tumor Genotype Is an Independent Prognostic Factor in Primary Gastrointestinal Stromal Tumors of Gastric Origin: A European Multicenter Analysis Based on ConticaGIST​
  Wozniak, A.; Rutkowski, P.; Schoffski, P.; Ray-Coquard, I.; Hostein, I.; Schildhaus, H.-U. & Le Cesne, A. et al.​ (2014) 
  Clinical Cancer Research, 20(23) pp. 6105​-6116​.​ DOI: https://doi.org/10.1158/1078-0432.CCR-14-1677 
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• 2014 | Journal Article | 
  ​ ​Comparison of Pre-Analytical FFPE Sample Preparation Methods and Their Impact on Massively Parallel Sequencing in Routine Diagnostics​
  Heydt, C.; Fassunke, J.; Kuenstlinger, H.; Ihle, M. A.; Koenig, K.; Heukamp, L. C. & Schildhaus, H.-U. et al.​ (2014) 
  PLoS ONE, 9(8) art. e104566​.​ DOI: https://doi.org/10.1371/journal.pone.0104566 
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• 2015 | Conference Abstract
  ​ ​Prevalence of NRG1 fusions in Caucasian NSCLC patients determined by fluorescence in situ hybridisation​
  Scheel, A. H.; Schmitz, K.; Wilsberg, L.; Fischer, R. N.; Merkelbach-Bruse, S.; Binot, E. & Plenker, D. et al.​ (2015)
  Journal of Thoracic Oncology, 10(9) 
  New york​: Elsevier Science Inc.
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• 2015 | Journal Article | 
  ​ ​MET Gene Copy Number Alterations and Expression of MET and Hepatocyte Growth Factor Are Potential Biomarkers in Angiosarcomas and Undifferentiated Pleomorphic Sarcomas​
  Schmitz, K.; Koeppen, H.; Binot, E.; Fassunke, J.; Kuenstlinger, H.; Ihle, M. A. & Heydt, C. et al.​ (2015) 
  PLoS ONE, 10(4) art. UNSP e0120079​.​ DOI: https://doi.org/10.1371/journal.pone.0120079 
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• 2015 | Journal Article
  ​ ​SRC inhibition represents a potential therapeutic strategy in liposarcoma​
  Sievers, E.; Trautmann, M.; Kindler, D.; Huss, S.; Gruenewald, I.; Dirksen, U. & Renner, M. et al.​ (2015) 
  International Journal of Cancer, 137(11) pp. 2578​-2588​.​ DOI: https://doi.org/10.1002/ijc.29645 
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• 2015 | Journal Article | 
  ​ ​Impact of updated HER2 testing guidelines in breast cancer re-evaluation of HERA trial fluorescence in situ hybridization data​
  Stoss, O. C.; Scheel, A.; Nagelmeier, I.; Schildhaus, H.-U.; Henkel, T.; Viale, G. & Jasani, B. et al.​ (2015) 
  Modern Pathology, 28(12) pp. 1528​-1534​.​ DOI: https://doi.org/10.1038/modpathol.2015.112 
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• 2015 | Journal Article | 
  ​ ​Ovarian-type epithelial tumours of the testis: immunohistochemical and molecular analysis of two serous borderline tumours of the testis​
  Buerger, T. ; Schildhaus, H.-U.; Inniger, R.; Hansen, J.; Mayer, P.; Schweyer, S. & Radzun, H. J. et al.​ (2015) 
  Diagnostic Pathology, 10 art. 118​.​ DOI: https://doi.org/10.1186/s13000-015-0342-9 
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• 2015 | Journal Article | 
  ​ ​Massively parallel sequencing fails to detect minor resistant subclones in tissue samples prior to tyrosine kinase inhibitor therapy​
  Heydt, C.; Kumm, N.; Fassunke, J.; Kuenstlinger, H.; Ihle, M. A.; Scheel, A. & Schildhaus, H.-U. et al.​ (2015) 
  BMC Cancer, 15 art. 291​.​ DOI: https://doi.org/10.1186/s12885-015-1311-0 
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• 2015 | Journal Article | 
  ​ ​c-myc copy number gain is a powerful prognosticator of disease outcome in cervical dysplasia.​
  Kübler, K.; Heinenberg, S.; Rudlowski, C.; Keyver-Paik, M.-D.; Abramian, A.; Merkelbach-Bruse, S. & Büttner, R. et al.​ (2015) 
  Oncotarget, 6(2) pp. 825​-835​.​ DOI: https://doi.org/10.18632/oncotarget.2706 
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• 2015 | Journal Article | 
  ​ ​ROS1 rearrangements in lung adenocarcinoma: prognostic impact, therapeutic options and genetic variability.​
  Scheffler, M.; Schultheis, A.; Teixido, C.; Michels, S.; Morales-Espinosa, D.; Viteri, S. & Hartmann, W. et al.​ (2015) 
  Oncotarget, 6(12) pp. 10577​-10585​.​ DOI: https://doi.org/10.18632/oncotarget.3387 
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• 2015 | Journal Article | 
  ​ ​FGFR2 is overexpressed in myxoid liposarcoma and inhibition of FGFR signaling impairs tumor growth in vitro.​
  Künstlinger, H.; Fassunke, J.; Schildhaus, H.-U.; Brors, B.; Heydt, C.; Ihle, M. A. & Mechtersheimer, G. et al.​ (2015) 
  Oncotarget, 6(24) pp. 20215​-20130​.​ DOI: https://doi.org/10.18632/oncotarget.4046 
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• 2016 | Journal Article
  ​ ​Sarcoma of the spleen with MDM2 expression​
  Hansen, T. C.; Titze, U.; Deeb, A.; Eikoetter, B.; Schuetz, M. & Schildhaus, H.-U.​ (2016) 
  Der Pathologe, 37(4) pp. 367​-370​.​ DOI: https://doi.org/10.1007/s00292-016-0168-6 
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