Author Ryazanov, Sergey
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2015 | Journal Article
The Novel Inhibitor “Anle145C” Efficiently Inhibits Fibril Formation of Islet Amyloid Polypeptide (IAPP) and uses Distinctly Different Modes of Action in the Absence and Presence of Membranes
Saravanan, M. S.; Ryazanov, S.; Leonov, A.; Seeliger, J.; Winter, R.; Giese, A. & Griesinger, C. et al. (2015)
Biophysical Journal, 108(2) pp. 256a. DOI: https://doi.org/10.1016/j.bpj.2014.11.1416
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2018 | Journal Article
The Small Molecule anle138b Shows Interaction with α-Synuclein Oligomers in Phospholipid Membranes
Antonschmidt, L.; Dervisoglu, R.; Ryazanov, S.; Leonov, A.; Wegstroth, M.; Giller, K. & Becker, S. et al. (2018)
Biophysical Journal, 114(3) pp. 560a. DOI: https://doi.org/10.1016/j.bpj.2017.11.3064
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2019 | Journal Article
Protein-Drug Interactions in the Membrane: The Small Molecule Anle138b and its Binding to α-Synuclein Oligomers
Antonschmidt, L.; Dervisoglu, R.; Ryazanov, S.; Leonov, A.; Wegstroth, M.; Giller, K. & Becker, S. et al. (2019)
Biophysical Journal, 116(3) pp. 352a. DOI: https://doi.org/10.1016/j.bpj.2018.11.1913
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2019 | Journal Article
Cardiolipin Promotes Pore-Forming Activity of Alpha-Synuclein Oligomers in Mitochondrial Membranes
Ghio, S.; Camilleri, A.; Caruana, M.; Ruf, V. C.; Schmidt, F.; Leonov, A. & Ryazanov, S. et al. (2019)
ACS Chemical Neuroscience, 10(8) pp. 3815-3829. DOI: https://doi.org/10.1021/acschemneuro.9b00320
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2019 | Journal Article | Research Paper |
Anle138b modulates α-synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy
Heras-Garvin, A.; Weckbecker, D.; Ryazanov, S.; Leonov, A.; Griesinger, C. ; Giese, A. & Wenning, G. K. et al. (2019)
Movement Disorders, 34(2) pp. 255-263. DOI: https://doi.org/10.1002/mds.27562
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2020 | Journal Article
Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin
Camilleri, A.; Ghio, S.; Caruana, M.; Weckbecker, D.; Schmidt, F.; Kamp, F. & Leonov, A. et al. (2020)
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1862(2) art. S000527361930210X. DOI: https://doi.org/10.1016/j.bbamem.2019.183064
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2020 | Journal Article |
Targeting α-synuclein by PD03 AFFITOPE® and Anle138b rescues neurodegenerative pathology in a model of multiple system atrophy: clinical relevance
Lemos, M.; Venezia, S.; Refolo, V.; Heras-Garvin, A.; Schmidhuber, S.; Giese, A. & Leonov, A. et al. (2020)
Translational Neurodegeneration, 9(1) art. 38. DOI: https://doi.org/10.1186/s40035-020-00217-y
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2020 | Journal Article | Research Paper |
11 C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α-Synuclein Fibrils in vitro and Crosses the Blood-Brain Barrier
Maurer, A.; Leonov, A.; Ryazanov, S.; Herfert, K.; Kuebler, L.; Buss, S. & Schmidt, F. et al. (2020)
ChemMedChem, 15(5) pp. 411-415. DOI: https://doi.org/10.1002/cmdc.201900689
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