Author Outeiro, Tiago F.

• 2018 | Book Chapter
  ​ ​Sirtuins in Brain and Neurodegenerative Disease​
  Szegő, É. M.; Outeiro, T. F.& Kazantsev, A. G.​ (2018)
  In: Introductory Review on Sirtuins in Biology, Aging, and Disease pp. 175​-195. ​Elsevier. DOI: https://doi.org/10.1016/B978-0-12-813499-3.00013-7 
  ​Details  DOI 

• 2022 | Journal Article | 
  ​ ​Therapeutic Targeting of Rab GTPases: Relevance for Alzheimer’s Disease​
  Jordan, K. L.; Koss, D. J.; Outeiro, T. F. & Giorgini, F.​ (2022) 
  Biomedicines, 10(5) pp. 1141​.​ DOI: https://doi.org/10.3390/biomedicines10051141 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Editorial: Personalized care in neurological diseases​
  Fernandes, J. B.; Godinho, C.; Outeiro, T. F. & Baixinho, C. L.​ (2023) 
  Frontiers in Human Neuroscience, 17 art. 1216902​.​ DOI: https://doi.org/10.3389/fnhum.2023.1216902 
  ​Details  DOI 

• 2023 | Journal Article | 
  ​ ​Glycosylation spectral signatures for glioma grade discrimination using Raman spectroscopy​
  Quesnel, A.; Coles, N.; Angione, C.; Dey, P.; Polvikoski, T. M.; Outeiro, T. F. & Islam, M. et al.​ (2023) 
  BMC Cancer, 23(1).​ DOI: https://doi.org/10.1186/s12885-023-10588-w 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Extracellular Vesicles for the Diagnosis of Parkinson's Disease: Systematic Review and Meta‐Analysis​
  Xylaki, M.; Chopra, A.; Weber, S.; Bartl, M.; Outeiro, T. F. & Mollenhauer, B.​ (2023) 
  Movement Disorders, art. mds.29497​.​ DOI: https://doi.org/10.1002/mds.29497 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Glycation modulates superoxide dismutase 1 aggregation and toxicity in models of sporadic amyotrophic lateral sclerosis​
  Monteiro Neto, J. R.; Ribeiro, G. D.; Magalhães, R. S. S.; Follmer, C.; Outeiro, T. F. & Eleutherio, E. C. A.​ (2023) 
  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1869(8) art. 166835​.​ DOI: https://doi.org/10.1016/j.bbadis.2023.166835 
  ​Details  DOI  PMID  PMC 

• 2023 | Journal Article
  ​ ​Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 ( NPTX1 ) as synapto‐axonal target in late‐stage Parkinson's disease​
  Warth Perez Arias, C. C.; Silbern, I.; Caldi Gomes, L.; Wartmann, H.; Dambeck, V.; Fanz, J. & Neuenroth, L. et al.​ (2023) 
  Journal of Neurochemistry, 166(5) pp. 862​-874​.​ DOI: https://doi.org/10.1111/jnc.15924 
  ​Details  DOI  PMID  PMC 

• 2023 | Journal Article | Overview
  ​ ​Defining the Riddle in Order to Solve It: There Is More Than One “Parkinson's Disease”​
  Outeiro, T. F.; Alcalay, R. N.; Antonini, A.; Attems, J.; Bonifati, V.; Cardoso, F. & Chesselet, M. et al.​ (2023) 
  Movement Disorders, art. mds.29419​.​ DOI: https://doi.org/10.1002/mds.29419 
  ​Details  DOI  PMID  PMC 

• 2023 | Journal Article | Overview
  ​ ​Targeting Biomolecular Condensation and Protein Aggregation against Cancer​
  Silva, J. L.; Foguel, D.; Ferreira, V. F.; Vieira, T. C. R. G.; Marques, M. A.; Ferretti, G. D. S. & Outeiro, T. F. et al.​ (2023) 
  Chemical Reviews, art. acs.chemrev.3c00131​.​ DOI: https://doi.org/10.1021/acs.chemrev.3c00131 
  ​Details  DOI  PMID  PMC 

• 2023 | Journal Article | Overview
  ​ ​AI and protein structure and function in neurological disease: relevance to disease management​
  Outeiro, T. F. & Vieira, T. C. R. G.​ (2023) 
  Nature Reviews Neurology, 19(8) pp. 453​-454​.​ DOI: https://doi.org/10.1038/s41582-023-00840-z 
  ​Details  DOI  PMID  PMC 

• 2023 | Journal Article | 
  ​ ​The alpha-synuclein oligomers activate nuclear factor of activated T-cell (NFAT) modulating synaptic homeostasis and apoptosis​
  Sant’Anna, R.; Robbs, B. K.; de Freitas, J. A.; dos Santos, P. P.; König, A.; Outeiro, T. F. & Foguel, D.​ (2023) 
  Molecular Medicine, 29(1) art. 111​.​ DOI: https://doi.org/10.1186/s10020-023-00704-8 
  ​Details  DOI  PMID  PMC 

• 2024 | Journal Article
  ​ ​Regional AT-8 reactive tau species correlate with intracellular Aβ levels in cases of low AD neuropathologic change​
  Malik, N.; Miah, M.-U.; Galgani, A.; McAleese, K.; Walker, L.; LeBeau, F. E. & Attems, J. et al.​ (2024) 
  Acta Neuropathologica, 147(1).​ DOI: https://doi.org/10.1007/s00401-024-02691-4 
  ​Details  DOI 

• 2024 | Journal Article
  ​ ​Inhibition of 26S proteasome activity by α‐synuclein is mediated by the proteasomal chaperone Rpn14/ PAAF1​
  Galka, D.; Ali, T. T.; Bast, A.; Niederleithinger, M.; Gerhardt, E.; Motosugi, R. & Sakata, E. et al.​ (2024) 
  Aging Cell, art. e14128​.​ DOI: https://doi.org/10.1111/acel.14128 
  ​Details  DOI  arXiv 

• 2024 | Preprint
  ​ ​Synphilin-1 as a modulator of aSyn assembly​
  Lázaro, D. F.; Amen, T.; Gerhardt, E.; Santos, P. I.; Milovanovic, D.; Höglinger, G.& Outeiro, T. F.​ (2024). DOI: https://doi.org/10.1101/2024.03.05.583522 
  ​Details  DOI 

• 2024 | Journal Article
  ​ ​Towards a biological diagnosis of PD​
  Chopra, A.; Lang, A. E.; Höglinger, G. & Outeiro, T. F.​ (2024) 
  Parkinsonism & Related Disorders, art. 106078​.​ DOI: https://doi.org/10.1016/j.parkreldis.2024.106078 
  ​Details  DOI 

• 2024 | Journal Article
  ​ ​Uncovering potential diagnostic and pathophysiological roles of α-synuclein and DJ-1 in melanoma​
  Quesnel, A.; Martin, L. D.; Tarzi, C.; Lenis, V. P.; Coles, N.; Islam, M. & Angione, C. et al.​ (2024) 
  Cancer Medicine,.​ DOI: https://doi.org/10.1002/cam4.6900 
  ​Details  DOI  PMID  PMC 

• 2024 | Journal Article
  ​ ​Substitution of Met-38 to Ile in γ-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid​
  Aubrey, L. D.; Ninkina, N.; Ulamec, S. M.; Abramycheva, N. Y.; Vasili, E.; Devine, O. M. & Wilkinson, M. et al.​ (2024) 
  Proceedings of the National Academy of Sciences of the United States of America, 121(2) art. e2309700120​.​ DOI: https://doi.org/10.1073/pnas.2309700120 
  ​Details  DOI  PMID  PMC 

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