Author Oetjen, Elke

1 to 20 of 52 Items
  • 2000 | Journal Article
    ​ ​Insulin responsiveness of the glucagon gene conferred by interactions between proximal promoter and more distal enhancer-like elements involving the paired-domain transcription factor Pax6​
    Grzeskowiak, R.; Amin, J.; Oetjen, E. & Knepel, W.​ (2000) 
    Journal of Biological Chemistry, 275(39) pp. 30037​-30045​.​ DOI: https://doi.org/10.1074/jbc.M000984200 
    ​Details  DOI  PMID  PMC  WoS 
  • 2001 | Conference Abstract
    ​ ​Effect of the dual leucine zipper bearing kinase on membrane-depolarization-stimulated CRE/CREB-dependent transcription​
    Oetjen, E.; Lechleiter, A.; Blume, R.; Nihalani, D.; Holzman, L. & Knepel, W.​ (2001)
    Naunyn-Schmiedeberg s Archives of Pharmacology, 363(4) 
    New york​: Springer.
    ​Details  WoS 
  • 2002 | Conference Abstract
    ​ ​Inhibition of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and FK506 in a pancreatic beta-cell line and in primary mature pancreatic islets of transgenic mice​
    Oetjen, E.; Grapentin, D.; Baun, D.; Blume, R.; Krause, D.; Beimesche, S. & Cierny, I. et al.​ (2002)
    Naunyn-Schmiedeberg s Archives of Pharmacology, 365 
    New york​: Springer.
    ​Details  WoS 
  • 2003 | Conference Abstract
    ​ ​Contribution of the EP4-receptor, PKA and CREB to intrinsic MDR1B overexpression in rat hepatocyte cultures​
    Ziemann, C.; Rudell, G.; Riecke, A.; Steinfelder, H. J.; Oetjen, E. & Hirsch-Ernst, K. I.​ (2003)
    Naunyn-Schmiedeberg s Archives of Pharmacology, 367 ​44th Meeting of the Deutsche-Gesellschaft-fur-Experimentelle-und-Klinische-Pharmakologie-und Toxikologie/20th Gesellschaft-fur-Umwelt-Mutationsforschung​, MAINZ, GERMANY.
    New york​: Springer.
    ​Details  WoS 
  • 2003 | Conference Abstract
    ​ ​The map kinase kinase kinase 1 inhibits CREB transcriptional activity stimulated by cyclic amp and membrane depolarization​
    Oetjen, E.; Grandke, G.; Blume, R. & Knepel, W.​ (2003)
    Naunyn-Schmiedeberg s Archives of Pharmacology, 367 ​44th Meeting of the Deutsche-Gesellschaft-fur-Experimentelle-und-Klinische-Pharmakologie-und Toxikologie/20th Gesellschaft-fur-Umwelt-Mutationsforschung​, MAINZ, GERMANY.
    New york​: Springer.
    ​Details  WoS 
  • 2003 | Journal Article
    ​ ​Regulation of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and tacrolimus at concentrations that inhibit calcineurin activity and involving the transcription factor CREB​
    Oetjen, E.; Grapentin, D.; Blume, R.; Seeger, M.; Krause, D.; Eggers, A. & Knepel, W.​ (2003) 
    Naunyn-Schmiedeberg s Archives of Pharmacology, 367(3) pp. 227​-236​.​ DOI: https://doi.org/10.1007/s00210-003-0694-7 
    ​Details  DOI  PMID  PMC  WoS 
  • 2003 | Journal Article
    ​ ​Inhibition of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and tacrolimus in primary, mature islets of transgenic mice​
    Oetjen, E.; Baun, D.; Beimesche, S.; Krause, D.; Cierny, I.; Blume, R. & Dickel, C. et al.​ (2003) 
    Molecular Pharmacology, 63(6) pp. 1289​-1295​.​ DOI: https://doi.org/10.1124/mol.63.6.1289 
    ​Details  DOI  PMID  PMC  WoS 
  • 2004 | Conference Abstract
    ​ ​The map kinase kinase kinase I enhances the transcriptional activity of PAX6 and PPAR gamma​
    Oetjen, E.; Theuner, Y.; Blume, R. & Knepel, W.​ (2004)
    Naunyn-Schmiedeberg s Archives of Pharmacology, 369 ​45th Spring Meeting of the German-Society-for-Experimental-and-Clinical-Pharmacology-and-Toxicology​, Mainz, GERMANY.
    New york​: Springer.
    ​Details  WoS 
  • 2004 | Conference Abstract
    ​ ​The map kinase kinase kinase 1 does not diminish cylic AMP-induced phosphorylation of CREB on Ser-119​
    Schlag, C.; Oetjen, E.; Blume, R. & Knepel, W.​ (2004)
    Naunyn-Schmiedeberg s Archives of Pharmacology, 369 ​45th Spring Meeting of the German-Society-for-Experimental-and-Clinical-Pharmacology-and-Toxicology​, Mainz, GERMANY.
    New york​: Springer.
    ​Details  WoS 
  • 2005 | Conference Abstract
    ​ ​Inhibition of the inter-action between CREB and its coactivator cbp by MEKK1 as revealed by fret​
    Oetjen, E.; Schlag, C.; Mayr, B. M.; Blume, R. & Knepel, W.​ (2005)
    Naunyn-Schmiedeberg s Archives of Pharmacology, 371 ​46th Spring Meeting of the Deutsche-Gesellschaft-fur-Experimentelle-und-Klinische-Pharmakologie-und Toxikologie​, Mainz, GERMANY.
    New york​: Springer.
    ​Details  WoS 
  • 2005 | Journal Article
    ​ ​Characterization of a novel Foxa (hepatocyte nuclear factor-3) site in the glucagon promoter that is conserved between rodents and humans​
    Sharma, S. K.; Leinemann, U.; Ratke, R.; Oetjen, E.; Blume, R.; Dickel, C. & Knepel, W.​ (2005) 
    Biochemical Journal, 389 pp. 831​-841​.​ DOI: https://doi.org/10.1042/BJ20050334 
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Journal Article
    ​ ​Protein kinase B activity is sufficient to mimic the effect of insulin on glucagon gene transcription​
    Schinner, S.; Barthel, A.; Dellas, C.; Grzeskowiak, R.; Sharma, S. K.; Oetjen, E. & Blume, R. et al.​ (2005) 
    Journal of Biological Chemistry, 280(8) pp. 7369​-7376​.​ DOI: https://doi.org/10.1074/jbc.M408560200 
    ​Details  DOI  PMID  PMC  WoS 
  • 2005 | Journal Article
    ​ ​The immunosuppressive drugs cyclosporin A and tacrolimus inhibit membrane depolarization-induced CREB transcriptional activity at the coactivator level​
    Oetjen, E.; Thoms, K. M.; Laufer, Y.; Pape, D.; Blume, R.; Li, P. F. & Knepel, W.​ (2005) 
    British Journal of Pharmacology, 144(7) pp. 982​-993​.​ DOI: https://doi.org/10.1038/sj.bjp.0706127 
    ​Details  DOI  PMID  PMC  WoS 
  • 2006 | Conference Abstract
    ​ ​The immunosuppressive drug cyclosporine A induces apoptotic beta-cell death​
    Oetjen, E.; Plaumann, S.; Steinfelder, H. J. & Knepel, W.​ (2006)
    Naunyn-Schmiedeberg s Archives of Pharmacology, 372 pp. 67​-68. ​47th Spring Meeting of the Deutsche-Gesellschaft-fur-Experimentelle-und-Klinische-Pharmakologie-und Toxikologie​, Mainz, GERMANY.
    New york​: Springer.
    ​Details  WoS 
  • 2006 | Conference Paper
    ​ ​The role of prostaglandin E receptor-dependent signaling via cAMP in mdr1b gene activation in primary rat hepatocyte cultures​
    Ziemann, C.; Riecke, A.; Rudell, G.; Oetjen, E.; Steinfelder, H. J.; Lass, C. & Kahl, G. F. et al.​ (2006)
    Journal of Pharmacology and Experimental Therapeutics, 317(1) pp. 378​-386. ​15th International Symposium on Microsomes and Drug Oxidations​, Mainz, GERMANY.
    Bethesda​: Amer Soc Pharmacology Experimental Therapeutics. DOI: https://doi.org/10.1124/jpet.105.094193 
    ​Details  DOI  PMID  PMC  WoS 
  • 2006 | Journal Article | 
    ​ ​Inhibition of membrane depolarisation-induced transcriptional activity of cyclic AMP response element binding protein (CREB) by the dual-leucine-zipper-bearing kinase in a pancreatic islet beta cell line​
    Oetjen, E.; Lechleiter, A.; Blume, R.; Nihalani, D.; Holzman, L. & Knepel, W.​ (2006) 
    Diabetologia, 49(2) pp. 332​-342​.​ DOI: https://doi.org/10.1007/s00125-005-0087-1 
    ​Details  DOI  PMID  PMC  WoS 
  • 2007 | Conference Abstract
    ​ ​Increase of interleukin-1beta-induced beta-cell apoptosis by the dual leucine zipper bearing kinase​
    Boerchers, S.; Blume, R.; Knepel, W. & Oetjen, E.​ (2007)
    Experimental and Clinical Endocrinology & Diabetes, 115 
    Stuttgart​: Johann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh.
    ​Details  WoS 
  • 2007 | Conference Abstract
    ​ ​Identification of a GSK3 beta phosphorylation sites within the C-terminus of the transcriptional coactivator CBP​
    Matsiulka, A.; Oetjen, E. & Knepel, W.​ (2007)
    Experimental and Clinical Endocrinology & Diabetes, 115 
    Stuttgart​: Johann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh.
    ​Details  WoS 
  • 2007 | Conference Abstract
    ​ ​Chronic insulin exposure with a decrease of insulin receptors results in diminished insulin sensitivity of glucagon gene transcription in pancreatic alpha cells​
    Gonzalez-Aguirre, M.; Boeer, U.; Oetjen, E. & Knepel, W.​ (2007)
    Experimental and Clinical Endocrinology & Diabetes, 115 
    Stuttgart​: Johann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh.
    ​Details  WoS 
  • 2007 | Conference Abstract
    ​ ​Inhibition of MafA transcriptional activity contributes to the inhibition of human insulin gene transcription by MEKK1 and interleukin-1beta​
    Oetjen, E.; Blume, R.; Cierny, I.; Kutschenko, A.; Kraetzner, R.; Stein, R. & Knepel, W.​ (2007)
    Naunyn-Schmiedeberg s Archives of Pharmacology, 375 ​48th Spring Meeting of the Deutsche-Gesellschaft-fur Experimentelle-ung-Klinische-Pharmakologie-und-Toxikologie​, Mainz, GERMANY.
    New york​: Springer.
    ​Details  WoS 

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