Author Moll, Ute M.
-
2007 | Journal Article
The role of ubiquitination in the direct mitochondrial death program of p53
Marchenko, N. D. & Moll, U. M. (2007)
Cell Cycle, 6(14) pp. 1718-1723.
Details PMID PMC WoS
-
2007 | Journal Article
p73 suppresses polyploidy and aneuploidy in the absence of functional p53
Talos, F.; Nemajerova, A.; Flores, E. R.; Petrenko, O. & Moll, U. M. (2007)
Molecular Cell, 27(4) pp. 647-659. DOI: https://doi.org/10.1016/j.molcel.2007.06.036
Details DOI PMID PMC WoS
-
2008 | Journal Article
Mitochondrially targeted wild-type p53 induces apoptosis in a solid human tumor xenograft model
Palacios, G.; Crawford, H. C.; Vaseva, A. V. & Moll, U. M. (2008)
Cell Cycle, 7(16) pp. 2584-2590.
Details PMID PMC WoS
-
2008 | Journal Article
E2F1 plays a direct role in Rb stabilization and p53-independent tumor suppression
Palacios, G.; Talos, F.; Nemajerova, A.; Moll, U. M. & Petrenko, O. (2008)
Cell Cycle, 7(12) pp. 1776-1781. DOI: https://doi.org/10.4161/cc.7.12.6030
Details DOI PMID PMC WoS
-
2008 | Journal Article |
p53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest
Braun, C. J.; Zhang, X.; Savelyeva, I.; Wolff, S.; Moll, U. M.; Schepeler, T. & Orntoft, T. F. et al. (2008)
Cancer Research, 68(24) pp. 10094-10104. DOI: https://doi.org/10.1158/0008-5472.CAN-08-1569
Details DOI PMID PMC WoS
-
2008 | Journal Article |
p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity
Wolff, S.; Erster, S.; Palacios, G. & Moll, U. M. (2008)
Cell Research, 18(7) pp. 733-744. DOI: https://doi.org/10.1038/cr.2008.62
Details DOI PMID PMC WoS
-
2009 | Journal Article |
The alpha/beta carboxy-terminal domains of p63 are required for skin and limb development. New insights from the Brdm2 mouse which is not a complete p63 knockout but expresses p63 gamma-like proteins
Wolff, S.; Talos, F.; Palacios, G.; Beyer, U.; Dobbelstein, M. & Moll, U. M. (2009)
Cell Death and Differentiation, 16(8) pp. 1108-1117. DOI: https://doi.org/10.1038/cdd.2009.25
Details DOI PMID PMC WoS
-
2010 | Journal Article |
Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-alpha 3 binding
Marchenko, N. D.; Hanel, W.; Li, D.; Becker, K.; Reich, N. & Moll, U. M. (2010)
Cell Death and Differentiation, 17(2) pp. 255-267. DOI: https://doi.org/10.1038/cdd.2009.173
Details DOI PMID PMC WoS
-
2010 | Journal Article | Letter Note |
Brdm2-an aberrant hypomorphic p63 allele
Talos, F.; Wolff, S.; Beyer, U.; Dobbelstein, M. & Moll, U. M. (2010)
Cell Death and Differentiation, 17(1) pp. 184-186. DOI: https://doi.org/10.1038/cdd.2009.158
Details DOI PMID PMC WoS
-
2010 | Journal Article |
Loss of p73 promotes dissemination of Myc-induced B cell lymphomas in mice
Nemajerova, A.; Petrenko, O.; Truemper, L. H.; Palacios, G. & Moll, U. M. (2010)
Journal of Clinical Investigation, 120(6) pp. 2070-2080. DOI: https://doi.org/10.1172/JCI40331
Details DOI PMID PMC WoS
-
2011 | Journal Article
Endogenous retrovirus drives hitherto unknown proapoptotic p63 isoforms in the male germ line of humans and great apes
Beyer, U.; Moll-Rocek, J.; Moll, U. M. & Dobbelstein, M. (2011)
Proceedings of the National Academy of Sciences of the United States of America, 108(9) pp. 3624-3629. DOI: https://doi.org/10.1073/pnas.1016201108
Details DOI PMID PMC WoS
-
2011 | Journal Article
Functional Inactivation of Endogenous MDM2 and CHIP by HSP90 Causes Aberrant Stabilization of Mutant p53 in Human Cancer Cells
Li, D.; Marchenko, N. D.; Schulz, R.; Fischer, V.; Velasco-Hernandez, T.; Talos, F. & Moll, U. M. (2011)
Molecular Cancer Research, 9(5) pp. 577-588. DOI: https://doi.org/10.1158/1541-7786.MCR-10-0534
Details DOI PMID PMC WoS
-
2011 | Journal Article
While p73 is essential, p63 is completely dispensable for the development of the central nervous system
Holembowski, L.; Schulz, R.; Talos, F.; Scheel, A.; Holzman, S.; Dobbelstein, M. & Moll, U. M. (2011)
Cell Cycle, 10(4) pp. 680-689. DOI: https://doi.org/10.4161/cc.10.4.14859
Details DOI PMID PMC WoS
-
2012 | Journal Article
HSP90 inhibitor antagonizing MIF The specifics of pleiotropic cancer drug candidates
Schulz, R.; Dobbelstein, M. & Moll, U. M. (2012)
OncoImmunology, 1(8) pp. 1425-1426. DOI: https://doi.org/10.4161/onci.21173
Details DOI WoS
-
2012 | Review
Role of p53 family members p73 and p63 in human hematological malignancies
Alexandrova, E. M.& Moll, U. M. (2012)
Leukemia & Lymphoma, 53(11) pp. 2116-2129.
Taylor & Francis Ltd. DOI: https://doi.org/10.3109/10428194.2012.684348
Details DOI PMID PMC WoS
-
2012 | Journal Article
p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis
Vaseva, A. V.; Marchenko, N. D.; Ji, K.; Tsirka, S. E.; Holzmann, S. & Moll, U. M. (2012)
Cell, 149(7) pp. 1536-1548. DOI: https://doi.org/10.1016/j.cell.2012.05.014
Details DOI PMID PMC WoS
-
2012 | Journal Article |
Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression
Schulz, R.; Marchenko, N. D.; Holembowski, L.; Fingerle-Rowson, G.; Pesic, M.; Zender, L. & Dobbelstein, M. et al. (2012)
Journal of Experimental Medicine, 209(2) pp. 275-289. DOI: https://doi.org/10.1084/jem.20111117
Details DOI PMID PMC WoS
-
2014 | Journal Article
Targeting tumour-supportive cellular machineries in anticancer drug development
Dobbelstein, M. & Moll, U. M. (2014)
Nature Reviews Drug Discovery, 13(3) pp. 179-196. DOI: https://doi.org/10.1038/nrd4201
Details DOI PMID PMC WoS
-
2014 | Journal Article |
HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancer
Schulz, R.; Streller, F.; Scheel, A. H.; Rueschoff, J.; Reinert, M. C.; Dobbelstein, M. & Marchenko, N. D. et al. (2014)
Cell Death and Disease, 5 art. e980. DOI: https://doi.org/10.1038/cddis.2013.508
Details DOI PMID PMC WoS
-
2014 | Review
Targeting the heat shock protein 90: a rational way to inhibit macrophage migration inhibitory factor function in cancer
Schulz, R.& Moll, U. M. (2014)
Current Opinion in Oncology, 26(1) pp. 108-113.
Lippincott Williams & Wilkins. DOI: https://doi.org/10.1097/CCO.0000000000000036
Details DOI PMID PMC WoS