Author Marek, Kenneth

• 2013 | Journal Article
  ​ ​Association of Cerebrospinal Fluid beta-Amyloid 1-42, T-tau, P-tau(181), and alpha-Synuclein Levels With Clinical Features of Drug-Naive Patients With Early Parkinson Disease​
  Kang, J.-H.; Irwin, D. J.; Chen-Plotkin, A. S.; Siderowf, A.; Caspell, C.; Coffey, C. S. & Waligorska, T. et al.​ (2013) 
  JAMA Neurology, 70(10) pp. 1277​-1287​.​ DOI: https://doi.org/10.1001/jamaneurol.2013.3861 
  ​Details  DOI  PMID  PMC  WoS 

• 2016 | Journal Article
  ​ ​CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study​
  Kang, J.-H.; Mollenhauer, B.; Coffey, C. S.; Toledo, J. B.; Weintraub, D.; Galasko, D. R. & Irwin, D. J. et al.​ (2016) 
  Acta Neuropathologica, 131(6) pp. 935​-949​.​ DOI: https://doi.org/10.1007/s00401-016-1552-2 
  ​Details  DOI  PMID  PMC  WoS 

• 2017 | Journal Article
  ​ ​Baseline prevalence and longitudinal evolution of non-motor symptoms in early Parkinson’s disease: the PPMI cohort​
  Simuni, T.; Caspell-Garcia, C.; Coffey, C. S; Weintraub, D.; Mollenhauer, B. ; Lasch, S. & Tanner, C. M et al.​ (2017) 
  Journal of Neurology, Neurosurgery & Psychiatry, 89(1) pp. 78​-88​.​ DOI: https://doi.org/10.1136/jnnp-2017-316213 
  ​Details  DOI 

• 2017 | Journal Article | 
  ​ ​Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson’s disease​
  Eidson, L. N.; Kannarkat, G. T.; Barnum, C. J.; Chang, J.; Chung, J.; Caspell-Garcia, C. & Taylor, P. et al.​ (2017) 
  Journal of Neuroinflammation, 14(1).​ DOI: https://doi.org/10.1186/s12974-017-0935-1 
  ​Details  DOI 

• 2017 | Journal Article | 
  ​ ​Longitudinal CSF biomarkers in patients with early Parkinson disease and healthy controls​
  Mollenhauer, B. ; Caspell-Garcia, C. J; Coffey, C.; Taylor, P.; Shaw, L. M.; Trojanowski, J. Q. & Singleton, A. et al.​ (2017) 
  Neurology, 89(19) pp. 1959​-1969​.​ DOI: https://doi.org/10.1212/WNL.0000000000004609 
  ​Details  DOI  PMID  PMC 

• 2019 | Journal Article | 
  ​ ​Longitudinal analyses of cerebrospinal fluid α‐Synuclein in prodromal and early Parkinson's disease​
  Mollenhauer, B.; Caspell‐Garcia, C. J.; Coffey, C. S.; Taylor, P.; Singleton, A.; Shaw, L. M. & Trojanowski, J. Q. et al.​ (2019) 
  Movement Disorders, 34(9) pp. 1354​-1364​.​ DOI: https://doi.org/10.1002/mds.27806 
  ​Details  DOI 

• 2019 | Journal Article | 
  ​ ​Predicting Progression in Parkinson’s Disease Using Baseline and 1-Year Change Measures​
  Chahine, L. M.; Siderowf, A.; Barnes, J.; Seedorff, N.; Caspell-Garcia, C.; Simuni, T. & Coffey, C. S. et al.​ (2019) 
  Journal of Parkinson's Disease, 9(4) pp. 665​-679​.​ DOI: https://doi.org/10.3233/JPD-181518 
  ​Details  DOI 

• 2020 | Journal Article
  ​ ​Clinical and Dopamine Transporter Imaging Characteristics of Leucine Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross‐Sectional Study​
  Simuni, T.; Brumm, M. C.; Uribe, L.; Caspell‐Garcia, C.; Coffey, C. S.; Siderowf, A. & Alcalay, R. N. et al.​ (2020) 
  Movement Disorders, 35(5) pp. 833​-844​.​ DOI: https://doi.org/10.1002/mds.27989 
  ​Details  DOI 

• 2020 | Journal Article
  ​ ​Dopamine transporter imaging predicts clinically‐defined α ‐synucleinopathy in REM sleep behavior disorder​
  Chahine, L. M.; Brumm, M. C.; Caspell‐Garcia, C.; Oertel, W.; Mollenhauer, B. ; Amara, A. & Fernandez‐Arcos, A. et al.​ (2020) 
  Annals of Clinical and Translational Neurology, 8(1) pp. 201​-212​.​ DOI: https://doi.org/10.1002/acn3.51269 
  ​Details  DOI 

• 2020 | Journal Article | 
  ​ ​Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson's Disease Progression​
  Mollenhauer, B. ; Dakna, M.; Kruse, N. ; Galasko, D.; Foroud, T.; Zetterberg, H. & Schade, S.  et al.​ (2020) 
  Movement Disorders, 35(11) pp. 1999​-2008​.​ DOI: https://doi.org/10.1002/mds.28206 
  ​Details  DOI 

• 2021 | Journal Article | Research Paper | 
  ​ ​Biomarkers of neurodegeneration and glial activation validated in Alzheimer’s disease assessed in longitudinal cerebrospinal fluid samples of Parkinson’s disease​
  Bartl, M.; Dakna, M.; Galasko, D.; Hutten, S. J.; Foroud, T.; Quan, M. & Marek, K. et al.​ (2021) 
  PLoS One, 16(10) pp. e0257372​.​ DOI: https://doi.org/10.1371/journal.pone.0257372 
  ​Details  DOI 

• 2022 | Journal Article
  ​ ​Trial of Prasinezumab in Early-Stage Parkinson’s Disease​
  Pagano, G.; Taylor, K. I.; Anzures-Cabrera, J.; Marchesi, M.; Simuni, T.; Marek, K. & Postuma, R. B. et al.​ (2022) 
  New England Journal of Medicine, 387(5) pp. 421​-432​.​ DOI: https://doi.org/10.1056/NEJMoa2202867 
  ​Details  DOI 

• 2024 | Journal Article
  ​ ​A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research​
  Simuni, T.; Chahine, L. M; Poston, K.; Brumm, M.; Buracchio, T.; Campbell, M. & Chowdhury, S. et al.​ (2024) 
  The Lancet Neurology, 23(2) pp. 178​-190​.​ DOI: https://doi.org/10.1016/S1474-4422(23)00405-2 
  ​Details  DOI 

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