Author Leonov, Andrei

• 2007 | Journal Article
  ​ ​The C2A-C2B linker defines the high affinity Ca2+ binding mode of rabphilin-3A​
  Montaville, P.; Schlicker, C.; Leonov, A.; Zweckstetter, M.; Sheldrick, G. M. & Becker, S.​ (2007) 
  Journal of Biological Chemistry, 282(7) pp. 5015​-5025​.​ DOI: https://doi.org/10.1074/jbc.M606746200 
  ​Details  DOI  PMID  PMC  WoS 

• 2014 | Journal Article
  ​ ​ChemInform Abstract: Trapped in Misbelief for Almost 40 Years: Selective Synthesis of the Four Stereoisomers of Mefloquine.​
  Schuetzenmeister, N.; Mueller, M.; Reinscheid, U. M.; Griesinger, C.   & Leonov, A.​ (2014) 
  ChemInform, 45(20) pp. no​-no​.​ DOI: https://doi.org/10.1002/chin.201420217 
  ​Details  DOI 

• 2015 | Journal Article
  ​ ​The Novel Inhibitor “Anle145C” Efficiently Inhibits Fibril Formation of Islet Amyloid Polypeptide (IAPP) and uses Distinctly Different Modes of Action in the Absence and Presence of Membranes​
  Saravanan, M. S.; Ryazanov, S.; Leonov, A.; Seeliger, J.; Winter, R.; Giese, A. & Griesinger, C.  et al.​ (2015) 
  Biophysical Journal, 108(2) pp. 256a​.​ DOI: https://doi.org/10.1016/j.bpj.2014.11.1416 
  ​Details  DOI 

• 2017 | Journal Article | 
  ​ ​Cholesterol-mediated allosteric regulation of the mitochondrial translocator protein structure​
  Jaipuria, G.; Leonov, A.; Giller, K.; Vasa, S. K.; Jaremko, L.; Jaremko, M. & Linser, R. et al.​ (2017) 
  Nature Communications, 8 art. 14893​.​ DOI: https://doi.org/10.1038/ncomms14893 
  ​Details  DOI  PMID  PMC  WoS 

• 2018 | Journal Article
  ​ ​The Small Molecule anle138b Shows Interaction with α-Synuclein Oligomers in Phospholipid Membranes​
  Antonschmidt, L.; Dervisoglu, R.; Ryazanov, S.; Leonov, A.; Wegstroth, M.; Giller, K. & Becker, S. et al.​ (2018) 
  Biophysical Journal, 114(3) pp. 560a​.​ DOI: https://doi.org/10.1016/j.bpj.2017.11.3064 
  ​Details  DOI 

• 2019 | Journal Article
  ​ ​Protein-Drug Interactions in the Membrane: The Small Molecule Anle138b and its Binding to α-Synuclein Oligomers​
  Antonschmidt, L.; Dervisoglu, R.; Ryazanov, S.; Leonov, A.; Wegstroth, M.; Giller, K. & Becker, S. et al.​ (2019) 
  Biophysical Journal, 116(3) pp. 352a​.​ DOI: https://doi.org/10.1016/j.bpj.2018.11.1913 
  ​Details  DOI 

• 2019 | Journal Article
  ​ ​Cardiolipin Promotes Pore-Forming Activity of Alpha-Synuclein Oligomers in Mitochondrial Membranes​
  Ghio, S.; Camilleri, A.; Caruana, M.; Ruf, V. C.; Schmidt, F.; Leonov, A. & Ryazanov, S. et al.​ (2019) 
  ACS Chemical Neuroscience, 10(8) pp. 3815​-3829​.​ DOI: https://doi.org/10.1021/acschemneuro.9b00320 
  ​Details  DOI 

• 2019 | Journal Article | Research Paper | 
  ​ ​Anle138b modulates α-synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy​
  Heras-Garvin, A.; Weckbecker, D.; Ryazanov, S.; Leonov, A.; Griesinger, C. ; Giese, A. & Wenning, G. K. et al.​ (2019) 
  Movement Disorders, 34(2) pp. 255​-263​.​ DOI: https://doi.org/10.1002/mds.27562 
  ​Details  DOI  PMID  PMC 

• 2020 | Journal Article
  ​ ​Lanthanide Tagging of Oligonucleotides to Nucleobase for Paramagnetic NMR​
  Täubert, S.; Zhang, Y.; Martinez, M. M.; Siepel, F.; Wöltjen, E.; Leonov, A. & Griesinger, C. ​ (2020) 
  ChemBioChem, 21(23) pp. 3333​-3337​.​ DOI: https://doi.org/10.1002/cbic.202000417 
  ​Details  DOI 

• 2020 | Journal Article
  ​ ​Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin​
  Camilleri, A.; Ghio, S.; Caruana, M.; Weckbecker, D.; Schmidt, F.; Kamp, F. & Leonov, A. et al.​ (2020) 
  Biochimica et Biophysica Acta (BBA) - Biomembranes, 1862(2) art. S000527361930210X​.​ DOI: https://doi.org/10.1016/j.bbamem.2019.183064 
  ​Details  DOI 

• 2020 | Journal Article | 
  ​ ​Targeting α-synuclein by PD03 AFFITOPE® and Anle138b rescues neurodegenerative pathology in a model of multiple system atrophy: clinical relevance​
  Lemos, M.; Venezia, S.; Refolo, V.; Heras-Garvin, A.; Schmidhuber, S.; Giese, A. & Leonov, A. et al.​ (2020) 
  Translational Neurodegeneration, 9(1) art. 38​.​ DOI: https://doi.org/10.1186/s40035-020-00217-y 
  ​Details  DOI 

• 2020 | Journal Article | Research Paper | 
  ​ ​11 C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α-Synuclein Fibrils in vitro and Crosses the Blood-Brain Barrier​
  Maurer, A.; Leonov, A.; Ryazanov, S.; Herfert, K.; Kuebler, L.; Buss, S. & Schmidt, F. et al.​ (2020) 
  ChemMedChem, 15(5) pp. 411​-415​.​ DOI: https://doi.org/10.1002/cmdc.201900689 
  ​Details  DOI  PMID  PMC 

• 2023 | Journal Article
  ​ ​Real-time tracking of drug binding to influenza A M2 reveals a high energy barrier​
  Tekwani Movellan, K.; Wegstroth, M.; Overkamp, K.; Leonov, A.; Becker, S. & Andreas, L. B.​ (2023) 
  Journal of Structural Biology: X, 8 art. 100090​.​ DOI: https://doi.org/10.1016/j.yjsbx.2023.100090 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Anle138b interaction in α-synuclein aggregates by dynamic nuclear polarization NMR​
  Dervişoğlu, R.; Antonschmidt, L.; Nimerovsky, E.; Sant, V.; Kim, M.; Ryazanov, S. & Leonov, A. et al.​ (2023) 
  Methods,.​ DOI: https://doi.org/10.1016/j.ymeth.2023.04.002 
  ​Details  DOI  PMID  PMC 

Researcher

Sort

Items per Page