Author Krüger, Nadine

1 to 20 of 31 Items
  • 2016 | Journal Article
    ​ ​Recombinant mumps viruses expressing the batMuV fusion glycoprotein are highly fusion active and neurovirulent​
    Krüger, N.; Sauder, C.; Hoffmann, M.; Örvell, C.; Drexler, J. F.; Rubin, S. & Herrler, G.​ (2016) 
    Journal of General Virology, 97(11) pp. 2837​-2848​.​ DOI: https://doi.org/10.1099/jgv.0.000596 
    ​Details  DOI 
  • 2016 | Journal Article | 
    ​ ​The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells.​
    Hoffmann, M.; Krüger, N.; Zmora, P.; Wrensch, F.; Herrler, G. & Pöhlmann, S.​ (2016) 
    PloS one, 11(3) art. e0152134​.​ DOI: https://doi.org/10.1371/journal.pone.0152134 
    ​Details  DOI  PMID  PMC 
  • 2018 | Journal Article
    ​ ​Entry, Replication, Immune Evasion, and Neurotoxicity of Synthetically Engineered Bat-Borne Mumps Virus​
    Krüger, N.; Sauder, C.; Hüttl, S.; Papies, J.; Voigt, K.; Herrler, G. & Hardes, K. et al.​ (2018) 
    Cell Reports, 25(2) pp. 312​-320.e7​.​ DOI: https://doi.org/10.1016/j.celrep.2018.09.018 
    ​Details  DOI 
  • 2019 | Journal Article
    ​ ​Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells​
    Hoffmann, M.; Nehlmeier, I.; Brinkmann, C.; Krähling, V.; Behner, L.; Moldenhauer, A.-S. & Krüger, N. et al.​ (2019) 
    Journal of Virology, 93(3).​ DOI: https://doi.org/10.1128/JVI.01821-18 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Fusogenicity of the Ghana Virus (Henipavirus: Ghanaian bat henipavirus) Fusion Protein is Controlled by the Cytoplasmic Domain of the Attachment Glycoprotein​
    Voigt, K.; Hoffmann, M.; Drexler, J. F.; Müller, M. A.; Drosten, C.; Herrler, G. & Krüger, N.​ (2019) 
    Viruses, 11(9) art. 800​.​ DOI: https://doi.org/10.3390/v11090800 
    ​Details  DOI 
  • 2019 | Journal Article | 
    ​ ​Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of endosomal cathepsins​
    Plegge, T.; Spiegel, M.; Krüger, N.; Nehlmeier, I.; Winkler, M.; González Hernández, M. & Pöhlmann, S.​ (2019) 
    PLOS ONE, 14(4) art. e0214968​.​ DOI: https://doi.org/10.1371/journal.pone.0214968 
    ​Details  DOI  PMID  PMC 
  • 2020 | Journal Article
    ​ ​Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus​
    Kleine-Weber, H.; Schroeder, S.; Krüger, N.; Prokscha, A.; Naim, H. Y.; Müller, M. A. & Drosten, C. et al.​ (2020) 
    Emerging Microbes & Infections, 9(1) pp. 155​-168​.​ DOI: https://doi.org/10.1080/22221751.2020.1713705 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​The Amino Acid at Position 8 of the Proteolytic Cleavage Site of the Mumps Virus Fusion Protein Affects Viral Proteolysis and Fusogenicity​
    Hüttl, S.; Hoffmann, M.; Steinmetzer, T.; Sauder, C. & Krüger, N.​ (2020) 
    Journal of Virology, 94(22).​ DOI: https://doi.org/10.1128/JVI.01732-20 
    ​Details  DOI 
  • 2020 | Journal Article
    ​ ​SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor​
    Hoffmann, M.; Kleine-Weber, H.; Schroeder, S.; Krüger, N.; Herrler, T.; Erichsen, S. & Schiergens, T. S. et al.​ (2020) 
    Cell, 181(2) pp. 271​-280.e8​.​ DOI: https://doi.org/10.1016/j.cell.2020.02.052 
    ​Details  DOI 
  • 2020 | Journal Article | 
    ​ ​Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2​
    Hoffmann, M.; Mösbauer, K.; Hofmann-Winkler, H.; Kaul, A.; Kleine-Weber, H.; Krüger, N. & Gassen, N. C. et al.​ (2020) 
    Nature, 585(7826) pp. 588​-590​.​ DOI: https://doi.org/10.1038/s41586-020-2575-3 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Therapeutic Application of alpha-1-antitrypsin in COVID-19​
    Ritzmann, F.; Chitirala, P.; Krüger, N.; Hoffmann, M.; Zuo, W.; Lammert, F. & Smola, S. et al.​ (2021) 
    American Journal of Respiratory and Critical Care Medicine, art. rccm.202104-0833LE​.​ DOI: https://doi.org/10.1164/rccm.202104-0833LE 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​SARS-CoV-2 variant B.1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination​
    Hoffmann, M.; Hofmann-Winkler, H.; Krüger, N.; Kempf, A.; Nehlmeier, I.; Graichen, L. & Arora, P. et al.​ (2021) 
    Cell Reports, 36(3) art. S2211124721008287​.​ DOI: https://doi.org/10.1016/j.celrep.2021.109415 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​B.1.617.2 enters and fuses lung cells with increased efficiency and evades antibodies induced by infection and vaccination​
    Arora, P.; Sidarovich, A.; Krüger, N.; Kempf, A.; Nehlmeier, I.; Graichen, L. & Moldenhauer, A.-S. et al.​ (2021) 
    Cell Reports, 37(2) art. S2211124721012894​.​ DOI: https://doi.org/10.1016/j.celrep.2021.109825 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​SARS-CoV-2 mutations acquired in mink reduce antibody-mediated neutralization​
    Hoffmann, M.; Zhang, L.; Krüger, N.; Graichen, L.; Kleine-Weber, H.; Hofmann-Winkler, H. & Kempf, A. et al.​ (2021) 
    Cell Reports, 35(3) pp. 109017​.​ DOI: https://doi.org/10.1016/j.celrep.2021.109017 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies​
    Hoffmann, M.; Arora, P.; Groß, R.; Seidel, A.; Hörnich, B. F.; Hahn, A. S. & Krüger, N. et al.​ (2021) 
    Cell, 184(9) pp. 2384​-2393.e12​.​ DOI: https://doi.org/10.1016/j.cell.2021.03.036 
    ​Details  DOI 
  • 2021 | Journal Article
    ​ ​Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity​
    Hoffmann, M.; Hofmann-Winkler, H.; Smith, J. C.; Krüger, N.; Arora, P.; Sørensen, L. K. & Søgaard, O. S. et al.​ (2021) 
    EBioMedicine, 65 art. 103255​.​ DOI: https://doi.org/10.1016/j.ebiom.2021.103255 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​The Upper Respiratory Tract of Felids Is Highly Susceptible to SARS-CoV-2 Infection​
    Krüger, N.; Rocha, C.; Runft, S.; Krüger, J.; Färber, I.; Armando, F. & Leitzen, E. et al.​ (2021) 
    International Journal of Molecular Sciences, 22(19) pp. 10636​.​ DOI: https://doi.org/10.3390/ijms221910636 
    ​Details  DOI 
  • 2021 | Journal Article | 
    ​ ​Synergistic inhibition of SARS-CoV-2 cell entry by otamixaban and covalent protease inhibitors: pre-clinical assessment of pharmacological and molecular properties​
    Hempel, T.; Elez, K.; Krüger, N.; Raich, L.; Shrimp, J. H.; Danov, O. & Jonigk, D. et al.​ (2021) 
    Chemical Science,.​ DOI: https://doi.org/10.1039/D1SC01494C 
    ​Details  DOI 
  • 2022 | Journal Article | Research Paper
    ​ ​Alternatives to animal models and their application in the discovery of species susceptibility to SARS-CoV-2 and other respiratory infectious pathogens: A review​
    Runft, S.; Färber, I.; Krüger, J.; Krüger, N.; Armando, F.; Rocha, C. & Pöhlmann, S.  et al.​ (2022) 
    Veterinary Pathology / Veterinary / American College of Veterinary Pathologists, pp. 030098582110736​.​ DOI: https://doi.org/10.1177/03009858211073678 
    ​Details  DOI 
  • 2022 | Journal Article
    ​ ​Evidence for an ACE2-Independent Entry Pathway That Can Protect from Neutralization by an Antibody Used for COVID-19 Therapy​
    Hoffmann, M.; Sidarovich, A.; Arora, P.; Krüger, N.; Nehlmeier, I.; Kempf, A. & Graichen, L. et al.​ (2022) 
    mBio,.​ DOI: https://doi.org/10.1128/mbio.00364-22 
    ​Details  DOI 

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