Author Kool, Marcel

• 2013 | Journal Article
  ​ ​Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma​
  Zhukova, N.; Ramaswamy, V.; Remke, M.; Pfaff, E.; Shih, D. J. H.; Martin, D. C. & Castelo-Branco, P. et al.​ (2013) 
  Journal of Clinical Oncology, 31(23) pp. 2927​-+​.​ DOI: https://doi.org/10.1200/JCO.2012.48.5052 
  ​Details  DOI  PMID  PMC  WoS 

• 2014 | Journal Article | Letter Note
  ​ ​Subgroup-specific localization of human medulloblastoma based on pre-operative MRI​
  Wefers, A. K.; Warmuth-Metz, M.; Poeschl, J.; von Bueren, A. O.; Monoranu, C.-M.; Seelos, K. & Peraud, A. et al.​ (2014) 
  Acta Neuropathologica, 127(6) pp. 931​-933​.​ DOI: https://doi.org/10.1007/s00401-014-1271-5 
  ​Details  DOI  PMID  PMC  WoS 

• 2014 | Journal Article | 
  ​ ​WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma​
  Zhukova, N.; Ramaswamy, V.; Remke, M.; Martin, D. C.; Castelo-Branco, P.; Zhang, C. H. & Fraser, M. et al.​ (2014) 
  Acta Neuropathologica Communications, 2(1) art. 174​.​ DOI: https://doi.org/10.1186/s40478-014-0174-y 
  ​Details  DOI  PMID  PMC 

• 2014 | Journal Article | 
  ​ ​Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort​
  Pietsch, T.; Schmidt, R.; Remke, M.; Korshunov, A.; Hovestadt, V.; Jones, D. T. W. & Felsberg, J. et al.​ (2014) 
  Acta Neuropathologica, 128(1) pp. 137​-149​.​ DOI: https://doi.org/10.1007/s00401-014-1276-0 
  ​Details  DOI  PMID  PMC  WoS 

• 2016 | Conference Abstract
  ​ ​PROGNOSTIC RELEVANCE OF EPIGENETIC/BIOLOGICAL SUBGROUPS AND MYCC/MYCN GENE AMPLIFICATION IN A HOMOGENOUSLY TREATED METASTATIC MEDULLOBLASTOMA HIT2000 COHORT AGED 4-21 YEARS​
  von Bueren, A. O.; Jones, D. T. W.; Goschzik, T.; Kortmann, R.-D.; von Hoff, K.; Friedrich, C. & Mynarek, M. et al.​ (2016)
  Neuro-Oncology, 18 ​17th International Symposium on Pediatric Neuro-Oncology (ISPNO)​, Liverpool, ENGLAND.
  Cary​: Oxford Univ Press Inc.
  ​Details  WoS 

• 2016 | Journal Article
  ​ ​New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs​
  Sturm, D.; Orr, B.; Toprak, U.; Hovestadt, V.; Jones, D.; Capper, D. & Sill, M. et al.​ (2016) 
  Cell, 164(5) pp. 1060​-1072​.​ DOI: https://doi.org/10.1016/j.cell.2016.01.015 
  ​Details  DOI 

• 2016 | Journal Article
  ​ ​Treatment of Children and Adolescents With Metastatic Medulloblastoma and Prognostic Relevance of Clinical and Biologic Parameters​
  von Bueren, A. O.; Kortmann, R.-D.; von Hoff, K.; Friedrich, C.; Mynarek, M.; Mueller, K. & Goschzik, T. et al.​ (2016) 
  Journal of Clinical Oncology, 34(34) pp. 4151​-+​.​ DOI: https://doi.org/10.1200/JCO.2016.67.2428 
  ​Details  DOI  PMID  PMC  WoS 

• 2018 | Journal Article
  ​ ​Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma​
  Merk, D. J.; Ohli, J.; Merk, N. D.; Thatikonda, V.; Morrissy, S.; Schoof, M. & Schmid, S. N. et al.​ (2018) 
  Developmental Cell, 44(6) pp. 709​-724.e6​.​ DOI: https://doi.org/10.1016/j.devcel.2018.02.012 
  ​Details  DOI 

• 2018 | Journal Article | 
  ​ ​The landscape of genomic alterations across childhood cancers​
  Gröbner, S. N.; Worst, B. C.; Weischenfeldt, J.; Buchhalter, I.; Kleinheinz, K.; Rudneva, V. A. & Johann, P. D. et al.​ (2018) 
  Nature, 555(7696) pp. 321​-327​.​ DOI: https://doi.org/10.1038/nature25480 
  ​Details  DOI 

• 2019 | Journal Article
  ​ ​Newly Diagnosed Metastatic Intracranial Ependymoma in Children: Frequency, Molecular Characteristics, Treatment, and Outcome in the Prospective HIT Series​
  Benesch, M.; Mynarek, M.; Witt, H.; Warmuth‐Metz, M.; Pietsch, T.; Bison, B. & Pfister, S. M. et al.​ (2019) 
  The Oncologist, 24(9).​ DOI: https://doi.org/10.1634/theoncologist.2018-0489 
  ​Details  DOI 

• 2020 | Journal Article
  ​ ​Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort​
  Mynarek, M.; von Hoff, K.; Pietsch, T.; Ottensmeier, H.; Warmuth-Metz, M.; Bison, B. & Pfister, S. et al.​ (2020) 
  Journal of Clinical Oncology, 38(18) pp. 2028​-2040​.​ DOI: https://doi.org/10.1200/JCO.19.03057 
  ​Details  DOI 

• 2020 | Journal Article | 
  ​ ​Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis​
  Suwala, A. K.; Stichel, D.; Schrimpf, D.; Kloor, M.; Wefers, A. K.; Reinhardt, A. & Maas, S. L. N. et al.​ (2020) 
  Acta Neuropathologica, 141(1) pp. 85​-100​.​ DOI: https://doi.org/10.1007/s00401-020-02243-6 
  ​Details  DOI 

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