Author Kleine-Weber, Hannah
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2018 | Journal Article |
Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein
Kleine-Weber, H.; Elzayat, M. T.; Hoffmann, M. & Pöhlmann, S. (2018)
Scientific Reports, 8(1) art. 16597. DOI: https://doi.org/10.1038/s41598-018-34859-w
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2019 | Journal Article
Mutations in the Spike Protein of Middle East Respiratory Syndrome Coronavirus Transmitted in Korea Increase Resistance to Antibody-Mediated Neutralization
Kleine-Weber, H.; Elzayat, M. T.; Wang, L.; Graham, B. S.; Müller, M. A.; Drosten, C. & Pöhlmann, S. et al. (2019)
Journal of Virology, 93(2). DOI: https://doi.org/10.1128/JVI.01381-18
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2019 | Journal Article
Spike proteins of novel MERS-coronavirus isolates from North- and West-African dromedary camels mediate robust viral entry into human target cells
Kleine-Weber, H.; Pöhlmann, S. & Hoffmann, M. (2019)
Virology, 535 pp. 261-265. DOI: https://doi.org/10.1016/j.virol.2019.07.016
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2020 | Journal Article
Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus
Kleine-Weber, H.; Schroeder, S.; Krüger, N.; Prokscha, A.; Naim, H. Y.; Müller, M. A. & Drosten, C. et al. (2020)
Emerging Microbes & Infections, 9(1) pp. 155-168. DOI: https://doi.org/10.1080/22221751.2020.1713705
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2020 | Journal Article
Nafamostat Mesylate Blocks Activation of SARS-CoV-2: New Treatment Option for COVID-19
Hoffmann, M.; Schroeder, S.; Kleine-Weber, H.; Müller, M. A.; Drosten, C. & Pöhlmann, S. (2020)
Antimicrobial Agents and Chemotherapy, 64(6). DOI: https://doi.org/10.1128/AAC.00754-20
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2020 | Journal Article
A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells
Hoffmann, M.; Kleine-Weber, H. & Pöhlmann, S. (2020)
Molecular Cell, 78(4) pp. 779-784.e5. DOI: https://doi.org/10.1016/j.molcel.2020.04.022
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2020 | Journal Article
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Hoffmann, M.; Kleine-Weber, H.; Schroeder, S.; Krüger, N.; Herrler, T.; Erichsen, S. & Schiergens, T. S. et al. (2020)
Cell, 181(2) pp. 271-280.e8. DOI: https://doi.org/10.1016/j.cell.2020.02.052
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2020 | Journal Article |
LY6E impairs coronavirus fusion and confers immune control of viral disease
Pfaender, S.; Mar, K. B.; Michailidis, E.; Kratzel, A.; Boys, I. N.; V’kovski, P. & Fan, W. et al. (2020)
Nature Microbiology, 5(11) pp. 1330-1339. DOI: https://doi.org/10.1038/s41564-020-0769-y
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2020 | Journal Article |
Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2
Hoffmann, M.; Mösbauer, K.; Hofmann-Winkler, H.; Kaul, A.; Kleine-Weber, H.; Krüger, N. & Gassen, N. C. et al. (2020)
Nature, 585(7826) pp. 588-590. DOI: https://doi.org/10.1038/s41586-020-2575-3
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2020 | Journal Article |
Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods
Bošnjak, B.; Stein, S. C.; Willenzon, S.; Cordes, A. K.; Puppe, W.; Bernhardt, G. & Ravens, I. et al. (2020)
Cellular & Molecular Immunology, 18(4) pp. 936-944. DOI: https://doi.org/10.1038/s41423-020-00573-9
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2021 | Journal Article
SARS-CoV-2 mutations acquired in mink reduce antibody-mediated neutralization
Hoffmann, M.; Zhang, L.; Krüger, N.; Graichen, L.; Kleine-Weber, H.; Hofmann-Winkler, H. & Kempf, A. et al. (2021)
Cell Reports, 35(3) pp. 109017. DOI: https://doi.org/10.1016/j.celrep.2021.109017
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2021 | Journal Article
SARS-CoV-2 and SARS-CoV Spike-Mediated Cell-Cell Fusion Differ in Their Requirements for Receptor Expression and Proteolytic Activation
Hörnich, B. F.; Großkopf, A. K.; Schlagowski, S.; Tenbusch, M.; Kleine-Weber, H.; Neipel, F. & Stahl-Hennig, C. et al. (2021)
Journal of Virology, 95(9) art. e00002-21. DOI: https://doi.org/10.1128/JVI.00002-21
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2021 | Journal Article |
Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5
Schroeder, S.; Mache, C.; Kleine-Weber, H.; Corman, V. M.; Muth, D.; Richter, A. & Fatykhova, D. et al. (2021)
Nature Communications, 12(1). DOI: https://doi.org/10.1038/s41467-021-25519-1
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