Author Hoffmann, Markus

• 2011 | Journal Article
  ​ ​Comparative Analysis of Ebola Virus Glycoprotein Interactions With Human and Bat Cells​
  Kühl, A.; Hoffmann, M.; Müller, M. A.; Munster, V. J.; Gnirß, K.; Kiene, M. & Tsegaye, T. S. et al.​ (2011) 
  The Journal of Infectious Diseases, 204(suppl_3) pp. S840​-S849​.​ DOI: https://doi.org/10.1093/infdis/jir306 
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• 2015 | Journal Article
  ​ ​Interferon-Induced Transmembrane Protein–Mediated Inhibition of Host Cell Entry of Ebolaviruses​
  Wrensch, F.; Karsten, C. B.; Gnirß, K.; Hoffmann, M.; Lu, K.; Takada, A. & Winkler, M. et al.​ (2015) 
  Journal of Infectious Diseases, 212(suppl 2) pp. S210​-S218​.​ DOI: https://doi.org/10.1093/infdis/jiv255 
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• 2016 | Journal Article
  ​ ​Recombinant mumps viruses expressing the batMuV fusion glycoprotein are highly fusion active and neurovirulent​
  Krüger, N.; Sauder, C.; Hoffmann, M.; Örvell, C.; Drexler, J. F.; Rubin, S. & Herrler, G.​ (2016) 
  Journal of General Virology, 97(11) pp. 2837​-2848​.​ DOI: https://doi.org/10.1099/jgv.0.000596 
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• 2016 | Journal Article
  ​ ​The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies​
  Brinkmann, C.; Nehlmeier, I.; Walendy-Gnirß, K.; Nehls, J.; González Hernández, M.; Hoffmann, M. & Qiu, X. et al.​ (2016) 
  Journal of Virology, 90(24) pp. 11075​-11086​.​ DOI: https://doi.org/10.1128/JVI.01563-16 
  ​Details  DOI 

• 2016 | Journal Article | 
  ​ ​The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent.​
  Hoffmann, M.; González Hernández, M.; Berger, E.; Marzi, A. & Pöhlmann, S.​ (2016) 
  PloS one, 11(2) art. e0149651​.​ DOI: https://doi.org/10.1371/journal.pone.0149651 
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• 2016 | Journal Article | 
  ​ ​The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells.​
  Hoffmann, M.; Krüger, N.; Zmora, P.; Wrensch, F.; Herrler, G. & Pöhlmann, S.​ (2016) 
  PloS one, 11(3) art. e0152134​.​ DOI: https://doi.org/10.1371/journal.pone.0152134 
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• 2017 | Journal Article
  ​ ​A Polymorphism within the Internal Fusion Loop of the Ebola Virus Glycoprotein Modulates Host Cell Entry​
  Hoffmann, M.; Crone, L.; Dietzel, E.; Paijo, J.; González-Hernández, M.; Nehlmeier, I. & Kalinke, U. et al.​ (2017) 
  Journal of Virology, 91(9) art. e00177-17​.​ DOI: https://doi.org/10.1128/JVI.00177-17 
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• 2017 | Journal Article
  ​ ​Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins​
  Wrensch, F.; Hoffmann, M.; Gärtner, S.; Nehlmeier, I.; Winkler, M. & Pöhlmann, S.​ (2017) 
  Journal of Virology, 91(2) art. e01488-16​.​ DOI: https://doi.org/10.1128/JVI.01488-16 
  ​Details  DOI 

• 2017 | Journal Article | Research Paper | 
  ​ ​The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cells​
  Brinkmann, C.; Hoffmann, M.; Lübke, A.; Nehlmeier, I.; Krämer-Kühl, A.; Winkler, M.   & Pöhlmann, S. ​ (2017) 
  PLoS One, 12(12) art. e0189073​.​ DOI: https://doi.org/10.1371/journal.pone.0189073 
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• 2017 | Journal Article | 
  ​ ​Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.​
  Reinke, L. M.; Spiegel, M.; Plegge, T.; Hartleib, A.; Nehlmeier, I.; Gierer, S. & Hoffmann, M. et al.​ (2017) 
  PloS one, 12(6) art. e0179177​.​ DOI: https://doi.org/10.1371/journal.pone.0179177 
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• 2018 | Journal Article
  ​ ​TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1​
  Zmora, P.; Hoffmann, M.; Kollmus, H.; Moldenhauer, A.-S.; Danov, O.; Braun, A. & Winkler, M.  et al.​ (2018) 
  Journal of Biological Chemistry, 293(36) pp. 13863​-13873​.​ DOI: https://doi.org/10.1074/jbc.RA118.001273 
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• 2018 | Journal Article
  ​ ​A GXXXA Motif in the Transmembrane Domain of the Ebola Virus Glycoprotein Is Required for Tetherin Antagonism​
  González-Hernández, M.; Hoffmann, M.; Brinkmann, C.; Nehls, J.; Winkler, M.; Schindler, M. & Pöhlmann, S.​ (2018) 
  Journal of Virology, 92(13) art. e00403-18​.​ DOI: https://doi.org/10.1128/JVI.00403-18 
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• 2018 | Journal Article
  ​ ​Cell Entry of Influenza A Viruses: Sweet Talk between HA and CaV1.2​
  Hoffmann, M. & Pöhlmann, S.​ (2018) 
  Cell Host & Microbe, 23(6) pp. 697​-699​.​ DOI: https://doi.org/10.1016/j.chom.2018.05.019 
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• 2018 | Journal Article
  ​ ​Entry, Replication, Immune Evasion, and Neurotoxicity of Synthetically Engineered Bat-Borne Mumps Virus​
  Krüger, N.; Sauder, C.; Hüttl, S.; Papies, J.; Voigt, K.; Herrler, G. & Hardes, K. et al.​ (2018) 
  Cell Reports, 25(2) pp. 312​-320.e7​.​ DOI: https://doi.org/10.1016/j.celrep.2018.09.018 
  ​Details  DOI 

• 2018 | Journal Article | 
  ​ ​Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein​
  Kleine-Weber, H.; Elzayat, M. T.; Hoffmann, M. & Pöhlmann, S. ​ (2018) 
  Scientific Reports, 8(1) art. 16597​.​ DOI: https://doi.org/10.1038/s41598-018-34859-w 
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• 2019 | Journal Article
  ​ ​Calu-3 cells are largely resistant to entry driven by filovirus glycoproteins and the entry defect can be rescued by directed expression of DC-SIGN or cathepsin L​
  González-Hernández, M.; Müller, A.; Hoenen, T.; Hoffmann, M. & Pöhlmann, S. ​ (2019) 
  Virology, 532 pp. 22​-29​.​ DOI: https://doi.org/10.1016/j.virol.2019.03.020 
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• 2019 | Journal Article
  ​ ​Mutations in the Spike Protein of Middle East Respiratory Syndrome Coronavirus Transmitted in Korea Increase Resistance to Antibody-Mediated Neutralization​
  Kleine-Weber, H.; Elzayat, M. T.; Wang, L.; Graham, B. S.; Müller, M. A.; Drosten, C. & Pöhlmann, S.  et al.​ (2019) 
  Journal of Virology, 93(2).​ DOI: https://doi.org/10.1128/JVI.01381-18 
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• 2019 | Journal Article
  ​ ​Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells​
  Hoffmann, M.; Nehlmeier, I.; Brinkmann, C.; Krähling, V.; Behner, L.; Moldenhauer, A.-S. & Krüger, N. et al.​ (2019) 
  Journal of Virology, 93(3).​ DOI: https://doi.org/10.1128/JVI.01821-18 
  ​Details  DOI 

• 2019 | Journal Article
  ​ ​Release of Immunomodulatory Ebola Virus Glycoprotein-Containing Microvesicles Is Suppressed by Tetherin in a Species-Specific Manner​
  Nehls, J.; Businger, R.; Hoffmann, M.; Brinkmann, C.; Fehrenbacher, B.; Schaller, M. & Maurer, B. et al.​ (2019) 
  Cell Reports, 26(7) pp. 1841​-1853.e6​.​ DOI: https://doi.org/10.1016/j.celrep.2019.01.065 
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• 2019 | Journal Article
  ​ ​Spike proteins of novel MERS-coronavirus isolates from North- and West-African dromedary camels mediate robust viral entry into human target cells​
  Kleine-Weber, H.; Pöhlmann, S.   & Hoffmann, M.​ (2019) 
  Virology, 535 pp. 261​-265​.​ DOI: https://doi.org/10.1016/j.virol.2019.07.016 
  ​Details  DOI 

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