Author Hardeland, Rüdiger

• 2002 | Journal Article
  ​ ​Melatonin's unique radical scavenging properties - roles of its functional substituents as revealed by a comparison with its structural analogs​
  Poeggeler, B.; Thuermann, S.; Dose, A.; Schoenke, M.; Burkhardt, S. & Hardeland, R.​ (2002) 
  Journal of Pineal Research, 33(1) pp. 20​-30​.​ DOI: https://doi.org/10.1034/j.1600-079X.2002.01873.x 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Journal Article | 
  ​ ​Melatonin Beyond Its Classical Functions​
  Hardeland, R. & Poeggeler, B.​ (2008) 
  The Open Physiology Journal, 1 pp. 1​-22​.​ DOI: https://doi.org/10.2174/1874360900901010001 
  ​Details  DOI 

• 2009 | Journal Article | 
  ​ ​New approaches in the management of insomnia: weighing the advantages of prolonged-release melatonin and synthetic melatoninergic agonists.​
  Hardeland, R.​ (2009) 
  Neuropsychiatric disease and treatment, 5 pp. 341​-54​.​
  ​Details  PMID  PMC 

• 2010 | Journal Article | 
  ​ ​New Vistas on Oxidative Damage and Aging​
  Hardeland, R. & Coto-Montes, A.​ (2010) 
  The Open Biology Journal, 3 pp. 39​-52​.​
  ​Details 

• 2011 | Journal Article | 
  ​ ​Cognitive Enhancers in Moderate to Severe Alzheimer’s Disease​
  Hardeland, R.​ (2011) 
  Clinical Medicine Insights. Therapeutics, 3 pp. 459​-476​.​ DOI: https://doi.org/10.4137/CMT.S6344 
  ​Details  DOI 

• 2011 | Journal Article | 
  ​ ​Pharmacotherapy of Insomnia with Ramelteon: Safety, Efficacy and Clinical Applications​
  Pandi-Perumal, S. R.; Spence, D. W.; Verster, J. C.; Srinivasan, V.; Brown, G. M.; Cardinali, D. P. & Hardeland, R.​ (2011) 
  Journal of Central Nervous System Disease, 3 pp. 51​-65​.​ DOI: https://doi.org/10.4137/JCNSD.S1611 
  ​Details  DOI 

• 2011 | Journal Article | 
  ​ ​Therapeutic potential of melatonin and its analogs in Parkinson's disease: focus on sleep and neuroprotection.​
  Srinivasan, V.; Cardinali, D. P.; Srinivasan, U. S.; Kaur, C.; Brown, G. M.; Spence, D. W. & Hardeland, R. et al.​ (2011) 
  Therapeutic advances in neurological disorders, 4(5) pp. 297​-317​.​ DOI: https://doi.org/10.1177/1756285611406166 
  ​Details  DOI  PMID  PMC 

• 2017 | Journal Article | 
  ​ ​Inflammaging, Metabolic Syndrome and Melatonin: A Call for Treatment Studies​
  Cardinali, D. P. & Hardeland, R.​ (2017) 
  Neuroendocrinology, 104(4) pp. 382​-397​.​ DOI: https://doi.org/10.1159/000446543 
  ​Details  DOI  PMID  PMC  WoS 

• 2018 | Book Chapter
  ​ ​Melatonin​
  Hardeland, R.​ (2018)
  In: Reference Module in Biomedical Sciences. ​Elsevier. DOI: https://doi.org/10.1016/B978-0-12-801238-3.62140-2 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​Bacteriostatic Potential of Melatonin: Therapeutic Standing and Mechanistic Insights​
  He, F.; Wu, X.; Zhang, Q.; Li, Y.; Ye, Y.; Li, P. & Chen, S. et al.​ (2021) 
  Frontiers in Immunology, 12.​ DOI: https://doi.org/10.3389/fimmu.2021.683879 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​The Reserve/Maximum Capacity of Melatonin’s Synthetic Function for the Potential Dimorphism of Melatonin Production and Its Biological Significance in Mammals​
  Tan, D.-X. & Hardeland, R.​ (2021) 
  Molecules, 26(23) pp. 7302​.​ DOI: https://doi.org/10.3390/molecules26237302 
  ​Details  DOI 

• 2021 | Journal Article | Research Paper | 
  ​ ​Melatonin and Microglia​
  Hardeland, R.​ (2021) 
  International Journal of Molecular Sciences, 22(15) pp. 8296​.​ DOI: https://doi.org/10.3390/ijms22158296 
  ​Details  DOI 

• 2021 | Book Chapter
  ​ ​Sirtuins, melatonin, and the relevance of circadian oscillators​
  Hardeland, R.​ (2021)
  In: Sirtuin Biology in Medicine pp. 137​-151. ​Elsevier. DOI: https://doi.org/10.1016/B978-0-12-814118-2.00011-2 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​Divergent Importance of Chronobiological Considerations in High- and Low-dose Melatonin Therapies​
  Hardeland, R.​ (2021) 
  Diseases, 9(1).​ DOI: https://doi.org/10.3390/diseases9010018 
  ​Details  DOI 

• 2021 | Journal Article | Research Paper | 
  ​ ​Inducing sterile pyramidal neuronal death in mice to model distinct aspects of gray matter encephalitis​
  Wilke, J. B. H.; Hindermann, M.; Moussavi, A.; Butt, U. J.; Dadarwal, R.; Berghoff, S. A. & Sarcheshmeh, A. K. et al.​ (2021) 
  Acta Neuropathologica Communications, 9(1) art. 121​.​ DOI: https://doi.org/10.1186/s40478-021-01214-6 
  ​Details  DOI 

• 2021 | Journal Article | Overview | 
  ​ ​Addressing the ‘hypoxia paradox’ in severe COVID-19: literature review and report of four cases treated with erythropoietin analogues​
  Begemann, M.; Gross, O.; Wincewicz, D.; Hardeland, R.; Daguano Gastaldi, V.; Vieta, E. & Weissenborn, K. et al.​ (2021) 
  Molecular Medicine, 27(1) art. 120​.​ DOI: https://doi.org/10.1186/s10020-021-00381-5 
  ​Details  DOI  PMID  PMC 

• 2022 | Journal Article
  ​ ​COVID-19: Urgent Need to Redesign Anti-inflammatory Strategies for CNS Protection​
  Hardeland, R.​ (2022) 
  Central Nervous System Agents in Medicinal Chemistry, 22.​ DOI: https://doi.org/10.2174/1871524922666220329102633 
  ​Details  DOI 

• 2022 | Journal Article
  ​ ​Melatonin inhibits Gram-negative pathogens by targeting citrate synthase​
  He, F.; Liu, Y.; Li, P.; Wu, X.; Xia, Y.; Zhang, D. & Li, N. et al.​ (2022) 
  Science China. Life Sciences,.​ DOI: https://doi.org/10.1007/s11427-021-2032-9 
  ​Details  DOI 

• 2022 | Journal Article | 
  ​ ​Melatonin and the Programming of Stem Cells​
  Hardeland, R.​ (2022) 
  International Journal of Molecular Sciences, 23(4) pp. 1971​.​ DOI: https://doi.org/10.3390/ijms23041971 
  ​Details  DOI 

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