Author Hanisch, Uwe-Karsten

• 2004 | Conference Abstract
  ​ ​The microglia-activating potential of thrombin: Is the protease able to induce cyto- and chemokines?​
  Hanisch, U.-K.; van Rossum, D.; Gast, K.; Misselwitz, R.; Goldstein, G.; Koistinaho, J. & Moller, T.​ (2004)
  Acta Neuropathologica, 108(4) ​49th Annual Meeting of the German-Society-of-Neuropathology-and-Neuroanatomy​, Cologne, GERMANY.
  New york​: Springer.
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• 2004 | Journal Article
  ​ ​The tyrosine kinase inhibitor AG126 restores receptor signaling and blocks release functions in activated microglia (brain macrophages) by preventing a chronic rise in the intracellular calcium level​
  Kann, O.; Hoffmann, A. L.; Schumann, R. R.; Weber, J. R.; Kettenmann, H. & Hanisch, U.-K.​ (2004) 
  Journal of Neurochemistry, 90(3) pp. 513​-525​.​ DOI: https://doi.org/10.1111/j.1471-4159.2004.02534.x 
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• 2004 | Conference Paper
  ​ ​Microglia​
  van Rossum, D. & Hanisch, U.-K.​ (2004)
  Metabolic Brain Disease, 19(3-4) pp. 393​-411. ​3rd International Hannover Conference on Hepatic Encephalopathy​, Bremen, GERMANY.
  New york​: Kluwer Academic/plenum Publ. DOI: https://doi.org/10.1023/B:MEBR.0000043984.73063.d8 
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• 2004 | Journal Article
  ​ ​The microglia-activating potential of thrombin - The protease is not involved in the induction of proinflammatory cytokines and chemokines​
  Hanisch, U.-K.; van Rossum, D.; Xie, Y. H.; Gast, K.; Misselwitz, R.; Auriola, S. & Goldsteins, G. et al.​ (2004) 
  Journal of Biological Chemistry, 279(50) pp. 51880​-51887​.​ DOI: https://doi.org/10.1074/jbc.M408318200 
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• 2004 | Journal Article
  ​ ​Tyrosine kinase inhibition reduces inflammation in the acute stage of experimental pneumococcal meningitis​
  Angstwurm, K.; Hanisch, U.-K.; Gassemi, T.; Bastholm Bille, M.; Prinz, M.; Dirnagl, U. & Kettenmann, H. et al.​ (2004) 
  Infection and Immunity, 72(6) pp. 3294​-3298​.​ DOI: https://doi.org/10.1128/IAI.72.6.3294-3298.2004 
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• 2005 | Conference Abstract
  ​ ​Lack of Type 1 Interferon Receptor (IFNAR) leads to exacerbation of experimental autoimmune encephalomyelitis​
  Schmidt, H.; Mildner, A.; Hanisch, U.-K.; Bruck, W. W.; Kalinke, U. & Prinz, M. R.​ (2005)
  Acta Neuropathologica, 110(3) ​50th Annual Meeting of the German-Society-of-Neuropathology-and-Neuroanatomy​, Graz, AUSTRIA.
  New york​: Springer.
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• 2005 | Journal Article
  ​ ​Unraveling thrombin's true microglia-activating potential: markedly disparate profiles of pharmaceutical-grade and commercial-grade thrombin preparations​
  Weinstein, J. R.; Hong, S.; Kulman, J. D.; Bishop, C.; Kuniyoshi, J.; Andersen, H. & Ransom, B. R. et al.​ (2005) 
  Journal of Neurochemistry, 95(4) pp. 1177​-1187​.​ DOI: https://doi.org/10.1111/j.1471-4159.2005.03499.x 
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• 2006 | Conference Abstract
  ​ ​Type 1 interferon receptor (IFNAR)-dependent modulation of myeloid cell activation determines the course of experimental autoimmune encephalomyelitis​
  Schmidt, H.; Detje, C. N.; Mildner, A.; Hanisch, U.-K.; Gold, R.; Becher, B. & Brueck, W. et al.​ (2006)
  Acta Neuropathologica, 112(3) ​51st Annual Meeting of the German-Society-of-Neuropathology-and-Neuroanatomy​, Mannheim, GERMANY.
  New york​: Springer.
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• 2006 | Conference Abstract
  ​ ​Type 1 interferon receptor (IFNAR)-dependent modulation of myeloid cell activation determines the course of experimental autoimmune encephalomyelitis​
  Prinz, M. R.; Schmidt, H.; Detje, C. N.; Mildner, A.; Hanisch, U.-K.; Gold, R. & Becher, B. et al.​ (2006)
  Journal of Neuroimmunology, 178 pp. 153​-154. ​8th International Conference of Neuroimmunology​, Nagoya, JAPAN.
  Amsterdam​: Elsevier Science Bv.
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• 2006 | Conference Abstract
  ​ ​Phenotypic diversity of microglia and macrophages​
  Hanisch, U.-K.​ (2006)
  Journal of Neuroimmunology, 178 ​8th International Conference of Neuroimmunology​, Nagoya, JAPAN.
  Amsterdam​: Elsevier Science Bv.
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• 2006 | Conference Abstract
  ​ ​Type 1 interferon receptor (IFNAR)-dependent modulation of myeloid cell activation determines the course of experimental autoimmune encephalomyelitis​
  Prinz, M. R.; Schmidt, H.; Detje, C. N.; Mildner, A.; Knobeloch, K.; Hanisch, U.-K. & Gold, R. et al.​ (2006)
  MULTIPLE SCLEROSIS, 12 ​22nd Congress of the European-Committee-for-the-Treatment-and-Resarch-in-Multiple-Sclerosis​, Madrid, SPAIN.
  London​: Sage Publications Ltd.
  ​Details  WoS 

• 2006 | Journal Article
  ​ ​Streptococcus pneumoniae infection aggravates experimental autoimmune encephalomyelitis via toll-like receptor 2​
  Hermann, I.; Kellert, M.; Schmidt, H.; Mildner, A.; Hanisch, U.-K.; Brueck, W. & Prinz, M. R. et al.​ (2006) 
  Infection and Immunity, 74(8) pp. 4841​-4848​.​ DOI: https://doi.org/10.1128/IAI.00026-06 
  ​Details  DOI  WoS 

• 2006 | Conference Abstract
  ​ ​Activation of microglial cells by thrombin: you get what you pay for​
  Moller, T.; Weinstein, J. R.; Hong, S.; Bishop, C.; Andersen, H. & Hanisch, U.-K.​ (2006)
  Journal of Neurochemistry, 96 ​Annual Meeting of the American-Society-for-Neurochemistry​, Portland, OR.
  Oxford​: Blackwell Publishing.
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• 2006 | Journal Article
  ​ ​Activation of microglial cells by thrombin: Past, present, and future​
  Moller, T.; Weinstein, J. R. & Hanisch, U.-K.​ (2006) 
  Seminars in Thrombosis and Hemostasis, 32 pp. 69​-76​.​ DOI: https://doi.org/10.1055/s-2006-939556 
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• 2006 | Journal Article | Letter Note
  ​ ​Microglial phenotype: is the commitment reversible?​
  Schwartz, M.; Butovsky, O.; Bruck, W. W. & Hanisch, U.-K.​ (2006) 
  Trends in Neurosciences, 29(2) pp. 68​-74​.​ DOI: https://doi.org/10.1016/j.tins.2005.12.005 
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• 2007 | Conference Abstract
  ​ ​Microglia in the adult brain arise from Ly-6Chi monocytes only under defined host conditions​
  Mildner, A.; Schmidt, H.; Nitsche, M.; Mekler, D.; Hanisch, U.-K.; Mack, M. & Heikenwalder, M. et al.​ (2007)
  MULTIPLE SCLEROSIS, 13 ​23rd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis/12th Annual Conference of Rehabilitation in MS​, Prague, CZECH REPUBLIC.
  London​: Sage Publications Ltd.
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• 2007 | Conference Abstract
  ​ ​Microglial activation by TLR ligands: Usual and unusual suspects​
  Hanisch, U.-K.​ (2007)
  Neuroscience Research, 58 
  Clare​: Elsevier Ireland Ltd. DOI: https://doi.org/10.1016/j.neures.2007.06.130 
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• 2007 | Review
  ​ ​Microglia: active sensor and versatile effector cells in the normal and pathologic brain​
  Hanisch, U.-K.& Kettenmann, H.​ (2007)
  Nature Neuroscience, 10​(11) pp. 1387​-1394​.​
  Nature Publishing Group. DOI: https://doi.org/10.1038/nn1997 
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• 2007 | Conference Paper
  ​ ​A paediatric supratentorial primitive neuroectodermal tumour associated with malignant astrocytic transformation and a clonal origin of both components​
  Kuhn, S. A.; Hanisch, U.-K.; Ebmeier, K.; Beetz, C.; Brodhun, M.; Reichart, R. & Ewald, C. et al.​ (2007)
  Neurosurgical Review, 30(2) pp. 143​-149. ​56th Annual Meeting of the German-Society-of-Neurosurgery​, Strasbourg, GERMANY.
  New york​: Springer. DOI: https://doi.org/10.1007/s10143-007-0069-5 
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• 2007 | Journal Article
  ​ ​Fibronectin is elevated in the cerebrospinal fluid of patients suffering from bacterial meningitis and enhances inflammation caused by bacterial products in primary mouse microglial cell cultures​
  Goos, M.; Lange, P.; Hanisch, U.-K.; Prinz, M. R.; Scheffel, J.; Bergmann, R. & Ebert, S. et al.​ (2007) 
  Journal of Neurochemistry, 102(6) pp. 2049​-2060​.​ DOI: https://doi.org/10.1111/j.1471-4159.2007.04683.x 
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