Author Hamdan, Feda H.

• 2018 | Journal Article | 
  ​ ​Epigenetic Targeting of Aberrant Transcriptional Modulation in Pancreatic Cancer​
  Hamdan, F. H. & Johnsen, S. A.​ (2018) 
  Epigenomes, 2(2) pp. 8​.​ DOI: https://doi.org/10.3390/epigenomes2020008 
  ​Details  DOI 

• 2018 | Journal Article
  ​ ​Abstract 1472: The role of the BAF complex in Wnt signaling-mediated transcriptional regulation in colorectal cancer​
  Sen, M.; Hamdan, F. H.; Wang, X.; Rapp, J. & Johnsen, S. A.​ (2018) 
  Cancer Research, 78(13_Supplement) pp. 1472​-1472​.​ DOI: https://doi.org/10.1158/1538-7445.AM2018-1472 
  ​Details  DOI 

• 2018 | Journal Article
  ​ ​Abstract 3936: Bromodomain testis-specific protein BRDT is expressed in a subset of esophageal squamous cell carcinomas and controls expression of differentiation-associated genes​
  Wang, X.; Hamdan, F. H.; Sen, M.; Kutschat, A. P. & Johnsen, S. A.​ (2018) 
  Cancer Research, 78(13_Supplement) pp. 3936​-3936​.​ DOI: https://doi.org/10.1158/1538-7445.AM2018-3936 
  ​Details  DOI 

• 2018 | Journal Article
  ​ ​Abstract 2922: The utility of BET inhibition in the sensitization and re-sensitization of pancreatic cancer cells to paclitaxel​
  Hamdan, F. H.; Kutschat, A. P.; Sen, M.; Wang, X. & Johnsen, S. A.​ (2018) 
  Cancer Research, 78(13_Supplement) pp. 2922​-2922​.​ DOI: https://doi.org/10.1158/1538-7445.AM2018-2922 
  ​Details  DOI 

• 2019 | Journal Article | 
  ​ ​Cytosolic 5'-nucleotidase 1A is overexpressed in pancreatic cancer and mediates gemcitabine resistance by reducing intracellular gemcitabine metabolites.​
  Patzak, M. S.; Kari, V.; Patil, S.; Hamdan, F. H.; Goetze, R. G.; Brunner, M. & Gaedcke, J. et al.​ (2019) 
  EBioMedicine, 40 pp. 394​-405​.​ DOI: https://doi.org/10.1016/j.ebiom.2019.01.037 
  ​Details  DOI  PMID  PMC 

• 2020 | Journal Article
  ​ ​Characterization of a dual BET / HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma​
  Zhang, X.; Zegar, T.; Weiser, T.; Hamdan, F. H.; Berger, B.; Lucas, R. & Balourdas, D. et al.​ (2020) 
  International Journal of Cancer, 147(10) pp. 2847​-2861​.​ DOI: https://doi.org/10.1002/ijc.33137 
  ​Details  DOI 

• 2021 | Journal Article
  ​ ​Bromodomain protein BRDT directs ΔNp63 function and super-enhancer activity in a subset of esophageal squamous cell carcinomas​
  Wang, X.; Kutschat, A. P.; Yamada, M.; Prokakis, E.; Böttcher, P.; Tanaka, K. & Doki, Y. et al.​ (2021) 
  Cell Death and Differentiation, 28(7) pp. 2207​-2220​.​ DOI: https://doi.org/10.1038/s41418-021-00751-w 
  ​Details  DOI 

• 2021 | Journal Article | Research Paper
  ​ ​STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer​
  Kutschat, A. P.; Hamdan, F. H.; Wang, X.; Wixom, A. Q.; Najafova, Z.; Gibhardt, C. S. & Kopp, W. et al.​ (2021) 
  Cancer Research, art. canres.2874.2020​.​ DOI: https://doi.org/10.1158/0008-5472.CAN-20-2874 
  ​Details  DOI  PMID  PMC 

• 2021 | Journal Article | 
  ​ ​Store-Operated Calcium Entry: Shaping the Transcriptional and Epigenetic Landscape in Pancreatic Cancer​
  Kutschat, A. P.; Johnsen, S. A. & Hamdan, F. H.​ (2021) 
  Cells, 10(5).​ DOI: https://doi.org/10.3390/cells10050966 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma​
  Wang, X.; Kutschat, A. P.; Aggrey-Fynn, J.; Hamdan, F. H.; Graham, R. P.; Wixom, A. Q. & Souto, Y. et al.​ (2023) 
  Molecular Cancer Research, pp. OF1​-OF11​.​ DOI: https://doi.org/10.1158/1541-7786.MCR-22-0916 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​NFATc1 is a central mediator of EGFR-induced ARID1A chromatin dissociation during acinar cell reprogramming​
  Zhang, Z.; Wang, X.; Hamdan, F. H.; Likhobabina, A.; Patil, S.; Aperdannier, L. & Sen, M. et al.​ (2023) 
  Cellular and Molecular Gastroenterology and Hepatology,.​ DOI: https://doi.org/10.1016/j.jcmgh.2023.01.015 
  ​Details  DOI  PMID  PMC 

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