Author Gruber, Jens

• 2004 | Journal Article
  ​ ​RNA interference by osmotic lysis of pinosomes: liposome-independent transfection of siRNAs into mammalian cells​
  Gruber, J.; Boese, G.; Tuschl, T.; Osborn, M. & Weber, K.​ (2004) 
  BioTechniques, 37(1) pp. 96​-102​.​ DOI: https://doi.org/10.2144/04371RR01 
  ​Details  DOI 

• 2006 | Journal Article | Research Paper
  ​ ​Gene silencing with siRNA duplexes composed of target-mRNA-complementary and partially palindromic or partially complementary single-stranded siRNAs​
  Hossbach, M.; Gruber, J.; Osborn, M. ; Weber, K.   & Tuschl, T.​ (2006) 
  RNA Biology, 3(2) pp. 82​-89​.​ DOI: https://doi.org/10.4161/rna.3.2.3110 
  ​Details  DOI  PMID  PMC 

• 2010 | Journal Article
  ​ ​Human box C/D snoRNAs with miRNA like functions: expanding the range of regulatory RNAs​
  Brameier, M.; Herwig, A.; Reinhardt, R.; Walter, L. & Gruber, J.​ (2010) 
  Nucleic Acids Research, 39(2) pp. 675​-686​.​ DOI: https://doi.org/10.1093/nar/gkq776 
  ​Details  DOI 

• 2012 | Journal Article
  ​ ​Balance of human choline kinase isoforms is critical for cell cycle regulation​
  Gruber, J.; See Too, W. C.; Wong, M. T.; Lavie, A.; McSorley, T. & Konrad, M.​ (2012) 
  FEBS Journal, 279(11) pp. 1915​-1928​.​ DOI: https://doi.org/10.1111/j.1742-4658.2012.08573.x 
  ​Details  DOI 

• 2014 | Journal Article
  ​ ​Specific RNAi Mediated Gene Knockdown in Zebrafish Cell Lines​
  Gruber, J.; Manninga, H.; Tuschl, T.; Osborn, M.   & Weber, K. ​ (2014) 
  RNA Biology, 2(3) pp. 101​-105​.​ DOI: https://doi.org/10.4161/rna.2.3.2060 
  ​Details  DOI 

• 2016 | Journal Article
  ​ ​MicroRNA in rectal cancer​
  Azizian, A. ; Gruber, J.; Ghadimi, B M. & Gaedcke, J. ​ (2016) 
  World Journal of Gastrointestinal Oncology, 8(5) pp. 416​.​ DOI: https://doi.org/10.4251/wjgo.v8.i5.416 
  ​Details  DOI 

• 2016 | Journal Article | 
  ​ ​In Vivo siRNA Delivery Using JC Virus-like Particles Decreases the Expression of RANKL in Rats​
  Hoffmann, D. B. ; Boeker, K. O.; Schneider, S.; Eckermann-Felkl, E.; Schuder, A.; Komrakova, M. & Sehmisch, S. et al.​ (2016) 
  Molecular Therapy — Nucleic Acids, 5.​ DOI: https://doi.org/10.1038/mtna.2016.15 
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• 2017 | Journal Article | Research Paper | 
  ​ ​Changes of Microrna Levels in Plasma of Patients with Rectal Cancer during Chemoradiotherapy​
  Jo, P. ; Azizian, A. ; Salendo, J. ; Kramer, F. ; Bernhardt, M. ; Wolff, H. A.   & Gruber, J. et al.​ (2017) 
  International Journal of Molecular Sciences, 18(6) art. 1140​.​ DOI: https://doi.org/10.3390/ijms18061140 
  ​Details  DOI  WoS 

• 2017 | Journal Article | 
  ​ ​Dissecting miRNA gene repression on single cell level with an advanced fluorescent reporter system​
  Lemus-Diaz, N.; Böker, K. O.; Rodriguez-Polo, I.; Mitter, M.; Preis, J.; Arlt, M. & Gruber, J.​ (2017) 
  Scientific Reports, 7 pp. 45197​.​ DOI: https://doi.org/10.1038/srep45197 
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• 2017 | Journal Article | 
  ​ ​Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin​
  Zmora, P.; Molau-Blazejewska, P.; Bertram, S.; Walendy-Gnirß, K.; Nehlmeier, I.; Hartleib, A. & Moldenhauer, A.-S. et al.​ (2017) 
  PLOS ONE, 12(5) art. e0176597​.​ DOI: https://doi.org/10.1371/journal.pone.0176597 
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• 2018 | Journal Article
  ​ ​Enhanced Production of Exosome-Associated AAV by Overexpression of the Tetraspanin CD9​
  Schiller, L. T.; Lemus-Diaz, N.; Rinaldi Ferreira, R.; Böker, K. O.   & Gruber, J.​ (2018) 
  Molecular Therapy. Methods & Clinical Development, 9 pp. 278​-287​.​ DOI: https://doi.org/10.1016/j.omtm.2018.03.008 
  ​Details  DOI 

• 2018 | Journal Article
  ​ ​The Impact of the CD9 Tetraspanin on Lentivirus Infectivity and Exosome Secretion​
  Böker, K. O.; Lemus-Diaz, N.; Rinaldi Ferreira, R.; Schiller, L.; Schneider, S. & Gruber, J.​ (2018) 
  Molecular Therapy, 26(2) pp. 634​-647​.​ DOI: https://doi.org/10.1016/j.ymthe.2017.11.008 
  ​Details  DOI 

• 2018 | Journal Article | 
  ​ ​Effects of RANKL Knockdown by Virus-like Particle-Mediated RNAi in a Rat Model of Osteoporosis​
  Hoffmann, D. B.; Gruber, J.; Böker, K. O.; Deppe, D.; Sehmisch, S.; Schilling, A. F. & Lemus-Diaz, N. et al.​ (2018) 
  Molecular Therapy - Nucleic Acids, 12 pp. 443​-452​.​ DOI: https://doi.org/10.1016/j.omtn.2018.06.001 
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• 2020 | Journal Article
  ​ ​Integrated Analysis of Transcriptome and Secretome From Umbilical Cord Mesenchymal Stromal Cells Reveal New Mechanisms for the Modulation of Inflammation and Immune Activation​
  Cruz-Barrera, M.; Flórez-Zapata, N.; Lemus-Diaz, N.; Medina, C.; Galindo, C.-C.; González-Acero, L.-X. & Correa, L. et al.​ (2020) 
  Frontiers in Immunology, 11 art. 575488​.​ DOI: https://doi.org/10.3389/fimmu.2020.575488 
  ​Details  DOI 

• 2020 | Journal Article | 
  ​ ​Histological assessment of optogenetic tools to study fronto-visual and fronto-parietal cortical networks in the rhesus macaque​
  Fortuna, M. G. ; Hüer, J.; Guo, H.; Gruber, J.; Gruber-Dujardin, E.; Staiger, J. F.   & Scherberger, H.  et al.​ (2020) 
  Scientific Reports, 10(1).​ DOI: https://doi.org/10.1038/s41598-020-67752-6 
  ​Details  DOI 

• 2020 | Journal Article | Research Paper | 
  ​ ​The human box C/D snoRNA U3 is a miRNA source and miR-U3 regulates expression of sortin nexin 27​
  Lemus-Diaz, N.; Ferreira, R. R.; Bohnsack, K. E. ; Gruber, J. & Bohnsack, M. T. ​ (2020) 
  Nucleic Acids Research, 48(14) pp. 8074​-8089​.​ DOI: https://doi.org/10.1093/nar/gkaa549 
  ​Details  DOI  PMID  PMC 

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