Author Grade, Marian

• 2003 | Journal Article
  ​ ​Gain of chromosome 8q23-24 is a predictive marker for lymph node positivity in colorectal cancer​
  Ghadimi, B. M.; Grade, M.; Liersch, T.; Langer, C.; Siemer, A.; Fuzesi, L. & Becker, H.​ (2003) 
  Clinical Cancer Research, 9(5) pp. 1808​-1814​.​
  ​Details  PMID  PMC  WoS 

• 2004 | Journal Article | Letter Note
  ​ ​The impact of molecular pathology in oncology: The clinician's perspective​
  Grade, M.; Becker, H. & Ghadimi, B. M.​ (2004) 
  Cellular Oncology, 26(5-6) pp. 275​-278​.​
  ​Details  PMID  PMC  WoS 

• 2005 | Journal Article
  ​ ​Effectiveness of gene expression profiling for response prediction of rectal adenocarcinomas to preoperative chemoradiotherapy​
  Ghadimi, B. M.; Grade, M.; Difilippantonio, M. J.; Varma, S.; Simon, R.; Montagna, C. & Fuzesi, L. et al.​ (2005) 
  Journal of Clinical Oncology, 23(9) pp. 1826​-1838​.​ DOI: https://doi.org/10.1200/JCO.2005.00.406 
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• 2006 | Conference Abstract
  ​ ​Pretherapeutical gene expression profiling for response prediction of rectal adenocarcinomas to preoperative chemoradiotherapy and its impact on disease free survival​
  Grade, M.; Liersch, T.; Varma, S.; Difilippantonio, M. J.; Langer, C.; Simon, R. & Ried, T. et al.​ (2006)
  EJC SUPPLEMENTS, 4(6) pp. 51​-52. 
  Oxford​: Pergamon-elsevier Science Ltd. DOI: https://doi.org/10.1016/j.ejcsup.2006.04.127 
  ​Details  DOI  WoS 

• 2006 | Review
  ​ ​Molecular cytogenetics: Genomic imbalances in colorectal cancer and their clinical impact​
  Grade, M.; Becker, H.; Liersch, T.; Ried, T.& Ghadimi, B. M.​ (2006)
  Cellular Oncology, 28​(3) pp. 71​-84​.​
  Ios Press.
  ​Details  PMID  PMC  WoS 

• 2006 | Journal Article
  ​ ​Distinct Chromosomal Profiles in Metastasizing and Non-Metastasizing Colorectal Carcinomas​
  Ghadimi, B. M.; Grade, M.; Mönkemeyer, C.; Kulle, B.; Gaedcke, J.; Gunawan, B. & Langer, C. et al.​ (2006) 
  Analytical Cellular Pathology, 28(5-6) pp. 273​-281​.​
  ​Details  PMID  PMC  WoS 

• 2006 | Journal Article
  ​ ​Aneuploidy-dependent massive deregulation of the cellular transcriptome and apparent divergence of the Wnt/beta-catenin signaling pathway in human rectal carcinomas​
  Grade, M.; Ghadimi, B. M.; Varma, S.; Simon, R.; Wangsa, D.; Barenboim-Stapleton, L. & Liersch, T. et al.​ (2006) 
  Cancer Research, 66(1) pp. 267​-282​.​ DOI: https://doi.org/10.1158/0008-5472.CAN-05-2533 
  ​Details  DOI  PMID  PMC  WoS 

• 2007 | Conference Abstract
  ​ ​Causes and consequences of chromosomal aneuploidy in cancer cells​
  Ried, T.; Sengupta, K.; Camps, J.; Hummon, A. B.; Padilla-Nash, H. M.; Grade, M. & Ghadimi, B. M. et al.​ (2007)
  Cytometry Part A, 71A(9) ​17th Annual Meeting of the German-Society-of-Cytometry (DGfZ)​, Univ Hosp, Regensburg, Regensburg, GERMANY.
  Hoboken​: Wiley-liss.
  ​Details  WoS 

• 2007 | Journal Article
  ​ ​Gene expression profiling reveals a massive, aneuploidy-dependent transcriptional deregulation and distinct differences between lymph node-negative and lymph node-positive colon carcinomas​
  Grade, M.; Hoermann, P.; Becker, S.; Hummon, A. B.; Wangsa, D.; Varma, S. & Simon, R. et al.​ (2007) 
  Cancer Research, 67(1) pp. 41​-56​.​ DOI: https://doi.org/10.1158/0008-5472.CAN-06-1514 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Conference Abstract
  ​ ​RNAi-based identification of potential targets in colorectal cancers​
  Grade, M.; Hummon, A. B.; Camps, J.; Emons, G.; Spitzner, M.; Gaedcke, J. & Difilippantonio, M. J. et al.​ (2008)
  EJC SUPPLEMENTS, 6(12) ​20th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics​, Geneva, SWITZERLAND.
  Oxford​: Pergamon-elsevier Science Ltd. DOI: https://doi.org/10.1016/S1359-6349(08)72485-6 
  ​Details  DOI  WoS 

• 2008 | Conference Abstract
  ​ ​Exploiting the genome and transcriptome for individualized cancer diagnosis and treatment stratification​
  Ried, T.; Grade, M.; Heselmeyer-Haddad, K.; Camps, J.; Hummon, A.; Emons, G. & Auer, G. et al.​ (2008)
  Cellular Oncology, 30(2) ​Meeting of the International-Society-for-Cellular-Oncology (ISCO 2008)​, Amsterdam, NETHERLANDS.
  Amsterdam​: Ios Press.
  ​Details  WoS 

• 2008 | Conference Abstract
  ​ ​Identification and functional validation of candidate oncogenes in colorectal cancer​
  Emons, G.; Camps, J.; Grade, M.; Hummon, A.; Nguyen, Q.; Gaedcke, J. & Difilippantonio, M. J. et al.​ (2008)
  Cellular Oncology, 30(2) pp. 149​-150. ​Meeting of the International-Society-for-Cellular-Oncology (ISCO 2008)​, Amsterdam, NETHERLANDS.
  Amsterdam​: Ios Press.
  ​Details  WoS 

• 2008 | Journal Article | 
  ​ ​A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities (Retracted Article. See vol 106, pg 6878, 2009)​
  Garman, K. S.; Acharya, C. R.; Edelman, E.; Grade, M.; Gaedcke, J.; Sud, S. & Barry, W. et al.​ (2008) 
  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(49) pp. 19432​-19437​.​ DOI: https://doi.org/10.1073/pnas.0806674105 
  ​Details  DOI  PMID  PMC  WoS 

• 2008 | Journal Article | 
  ​ ​Chromosomal breakpoints in primary colon cancer cluster at sites of structural variants in the genome​
  Camps, J.; Grade, M.; Nguyen, Q. T.; Hoermann, P.; Becker, S.; Hummon, A. B. & Rodriguez, V. et al.​ (2008) 
  Cancer Research, 68(5) pp. 1284​-1295​.​ DOI: https://doi.org/10.1158/0008-5472.CAN-07-2864 
  ​Details  DOI  PMID  PMC  WoS 

• 2009 | Journal Article
  ​ ​Chromosomal copy number changes of locally advanced rectal cancers treated with preoperative chemoradiotherapy​
  Grade, M.; Gaedcke, J.; Wangsa, D.; Varma, S.; Beckmann, J.; Liersch, T. & Hess, C. et al.​ (2009) 
  CANCER GENETICS AND CYTOGENETICS, 193(1) pp. 19​-28​.​ DOI: https://doi.org/10.1016/j.cancergencyto.2009.03.016 
  ​Details  DOI  PMID  PMC  WoS 

• 2009 | Journal Article
  ​ ​Integrative Genomics Reveals Mechanisms of Copy Number Alterations Responsible for Transcriptional Deregulation in Colorectal Cancer​
  Camps, J.; Nguyen, Q. T.; Padilla-Nash, H. M.; Knutsen, T.; McNeil, N. E.; Wangsa, D. & Hummon, A. B. et al.​ (2009) 
  Genes Chromosomes and Cancer, 48(11) pp. 1002​-1017​.​ DOI: https://doi.org/10.1002/gcc.20699 
  ​Details  DOI  PMID  PMC  WoS 

• 2009 | Journal Article
  ​ ​Preoperative chemoradiotherapy in locally advanced rectal cancer: correlation of a gene expression-based response signature with recurrence​
  Liersch, T.; Grade, M.; Gaedcke, J.; Varma, S.; Difilippantonio, M. J.; Langer, C. & Hess, C. F. et al.​ (2009) 
  CANCER GENETICS AND CYTOGENETICS, 190(2) pp. 57​-65​.​ DOI: https://doi.org/10.1016/j.cancergencyto.2008.11.011 
  ​Details  DOI  PMID  PMC  WoS 

• 2010 | Conference Abstract
  ​ ​Silencing of TCF7L2 sensitizes colorectal cancer cells to radiation therapy​
  Grade, M.; Kendziorra, E.; Ahlborn, K.; Spitzner, M.; Gaedcke, J.; Rave-Fraenk, M. & Becker, H. et al.​ (2010)
  EJC SUPPLEMENTS, 8(7) ​22nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics​, Berlin, GERMANY.
  Oxford​: Pergamon-elsevier Science Ltd. DOI: https://doi.org/10.1016/S1359-6349(10)72008-5 
  ​Details  DOI  WoS 

• 2010 | Review
  ​ ​Molecular markers for response prediction in locally advanced rectal cancer. Is individualized therapy coming?​
  Liersch, T.; Gaedcke, J.; Grade, M.; Sprenger, T.; Conradi, L.-C.; Becker, H.& Ghadimi, B. M.​ (2010)
  Der Onkologe, 16​(8) pp. 779​-788​.​
  Springer. DOI: https://doi.org/10.1007/s00761-010-1866-y 
  ​Details  DOI  WoS 

• 2010 | Conference Abstract
  ​ ​Resection by pancreas carcinoma: significance for the therapy​
  Ghadimi, M. B.; Gaedcke, J.; Kitz, J.; Grade, M.; Cordes, C.; Liersch, T. & Becker, H.​ (2010)
  Onkologie, 33 
  Basel​: Karger.
  ​Details  WoS 

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