Author Gierer, Stefanie
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2012 | Journal Article |
Influenza and SARS-Coronavirus Activating Proteases TMPRSS2 and HAT Are Expressed at Multiple Sites in Human Respiratory and Gastrointestinal Tracts
Bertram, S.; Heurich, A.; Lavender, H.; Gierer, S.; Danisch, S.; Perin, P. & Lucas, J. M. et al. (2012)
PLoS ONE, 7(4) art. e35876. DOI: https://doi.org/10.1371/journal.pone.0035876
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2013 | Journal Article
Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia
Gierer, S.; Hofmann-Winkler, H.; Albuali, W. H.; Bertram, S.; Al-Rubaish, A. M.; Yousef, A. A. & Al-Nafaie, A. N. et al. (2013)
Emerging Infectious Diseases, 19(12) pp. 2034-2036. DOI: https://doi.org/10.3201/eid1912.130701
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2013 | Journal Article
Proteolytic activation of the SARS-coronavirus spike protein: Cutting enzymes at the cutting edge of antiviral research
Simmons, G.; Zmora, P.; Gierer, S.; Heurich, A. & Pöhlmann, S. (2013)
Antiviral Research, 100(3) pp. 605-614. DOI: https://doi.org/10.1016/j.antiviral.2013.09.028
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2013 | Journal Article
The Spike Protein of the Emerging Betacoronavirus EMC Uses a Novel Coronavirus Receptor for Entry, Can Be Activated by TMPRSS2, and Is Targeted by Neutralizing Antibodies
Gierer, S.; Bertram, S.; Kaup, F.; Wrensch, F.; Heurich, A.; Krämer-Kühl, A. & Welsch, K. et al. (2013)
Journal of Virology, 87(10) pp. 5502-5511. DOI: https://doi.org/10.1128/JVI.00128-13
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2013 | Journal Article
TMPRSS2 Activates the Human Coronavirus 229E for Cathepsin-Independent Host Cell Entry and Is Expressed in Viral Target Cells in the Respiratory Epithelium
Bertram, S.; Dijkman, R.; Habjan, M.; Heurich, A.; Gierer, S.; Glowacka, I. & Welsch, K. et al. (2013)
Journal of Virology, 87(11) pp. 6150-6160. DOI: https://doi.org/10.1128/JVI.03372-12
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2014 | Journal Article | Research Paper
TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein
Heurich, A.; Hofmann-Winkler, H.; Gierer, S.; Liepold, T.; Jahn, O. & Pöhlmann, S. (2014)
Journal of Virology, 88(2) pp. 1293-1307. DOI: https://doi.org/10.1128/JVI.02202-13
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2017 | Journal Article |
Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.
Reinke, L. M.; Spiegel, M.; Plegge, T.; Hartleib, A.; Nehlmeier, I.; Gierer, S. & Hoffmann, M. et al. (2017)
PloS one, 12(6) art. e0179177. DOI: https://doi.org/10.1371/journal.pone.0179177
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