Author Flügel, Alexander
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2004 | Journal Article
The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis
Kawakami, N.; Lassmann, S.; Li, Z.; Odoardi, F. ; Ritter, T.; Ziemssen, T. & Klinkert, W. E F et al. (2004)
Journal of Experimental Medicine, 199(2) pp. 185-197. DOI: https://doi.org/10.1084/jem.20031064
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2005 | Journal Article
Live imaging of effector cell trafficking and autoantigen recognition within the unfolding autoimmune encephalomyelitis lesion
Kawakami, N.; Nägerl, U V.; Odoardi, F. ; Bonhoeffer, T.; Wekerle, H. & Flügel, A. (2005)
Journal of Experimental Medicine, 201(11) pp. 1805-1814. DOI: https://doi.org/10.1084/jem.20050011
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2005 | Journal Article
Autoimmune CD4+ T cell memory: lifelong persistence of encephalitogenic T cell clones in healthy immune repertoires
Kawakami, N.; Odoardi, F. ; Ziemssen, T.; Bradl, M.; Ritter, T.; Neuhaus, O. & Lassmann, H. et al. (2005)
The Journal of Immunology, 175(1) pp. 69-81. DOI: https://doi.org/10.4049/jimmunol.175.1.69
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2007 | Journal Article
Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis
Odoardi, F. ; Kawakami, N.; Li, Z.; Cordiglieri, C.; Streyl, K.; Nosov, M. & Klinkert, W. E F et al. (2007)
Proceedings of the National Academy of Sciences of the United States of America, 104(3) pp. 920-925. DOI: https://doi.org/10.1073/pnas.0608383104
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2007 | Journal Article
Autoaggressive effector T cells in the course of experimental autoimmune encephalomyelitis visualized in the light of two-photon microscopy
Flügel, A.; Odoardi, F. ; Nosov, M. & Kawakami, N. (2007)
Journal of Neuroimmunology, 191(1-2) pp. 86-97. DOI: https://doi.org/10.1016/j.jneuroim.2007.09.017
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2014 | Journal Article |
Pain-induced skin autoimmunity
Odoardi, F. ; Neuhuber, W. & Flügel, A. (2014)
Cell Research, 24(9) pp. 1021-1022. DOI: https://doi.org/10.1038/cr.2014.80
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2015 | Journal Article
Calcium Signalling Triggered by NAADP in T Cells Determines Cell Shape and Motility During Immune Synapse Formation
Nebel, M.; Zhang, B.; Odoardi, F. ; Flügel, A.; Potter, B. V L & Guse, A. H (2015)
Messenger, 4(1) pp. 104-111. DOI: https://doi.org/10.1166/msr.2015.1045
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2016 | Book Chapter
In Vivo Visualization of (Auto)Immune Processes in the Central Nervous System of Rodents
Schläger, C.; Litke, T.; Flügel, A.& Odoardi, F. (2016)
In:Weissert, Robert (Ed.), Multiple Sclerosis: Methods and Protocols pp. 117-129. Springer. DOI: https://doi.org/10.1007/7651_2014_150
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2017 | Journal Article
Astrocytic expression of the CXCL12 receptor, CXCR7/ACKR3 is a hallmark of the diseased, but not developing CNS
Puchert, M.; Pelkner, F.; Stein, G.; Angelov, D. N; Boltze, J.; Wagner, D.-C. & Odoardi, F. et al. (2017)
Molecular and Cellular Neuroscience, 85 pp. 105-118. DOI: https://doi.org/10.1016/j.mcn.2017.09.001
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2018 | Journal Article |
Small Molecule Antagonists of NAADP-Induced Ca2+ Release in T-Lymphocytes Suggest Potential Therapeutic Agents for Autoimmune Disease
Zhang, B.; Watt, J. M.; Cordiglieri, C.; Dammermann, W.; Mahon, M. F.; Flügel, A. & Guse, A. H. et al. (2018)
Scientific Reports, 8(1). DOI: https://doi.org/10.1038/s41598-018-34917-3
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2018 | Journal Article |
Trapped in the epineurium: early entry into the endoneurium is restricted to neuritogenic T cells in experimental autoimmune neuritis
Mausberg, A. K; Szepanowski, F.; Odoardi, F. ; Flügel, A.; Kleinschnitz, C.; Stettner, M. & Kieseier, B. C (2018)
Journal of Neuroinflammation, 15(1) pp. 217. DOI: https://doi.org/10.1186/s12974-018-1259-5
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2019 | Journal Article
β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration
Lodygin, D.; Hermann, M.; Schweingruber, N.; Flügel-Koch, C.; Watanabe, T.; Schlosser, C. & Merlini, A. et al. (2019)
Nature, 566(7745) pp. 503-508. DOI: https://doi.org/10.1038/s41586-019-0964-2
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2019 | Journal Article |
Publisher Correction: β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration
Lodygin, D.; Hermann, M.; Schweingruber, N.; Flügel-Koch, C.; Watanabe, T.; Schlosser, C. & Merlini, A. et al. (2019)
Nature, 567(7749) pp. E15-E15. DOI: https://doi.org/10.1038/s41586-019-1047-0
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2023 | Preprint
A novel miR-99b-5p-Zbp1 pathway in microglia contributes to the pathogenesis of schizophrenia
Kaurani, L.; Islam, M. R.; Heilbronner, U.; Krüger, D. M.; Zhou, J.; Methi, A.& Strauss, J. et al. (2023). DOI: https://doi.org/10.1101/2023.03.21.533602
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2023 | Journal Article
Ovalbumin-specific CD4+ and CD8+ T cells contribute to different susceptibility for Theiler’s murine encephalomyelitis virus persistence
Wannemacher, R.; Reiß, A.; Rohn, K.; Lühder, F.; Flügel, A.; Baumgärtner, W. & Hülskötter, K. (2023)
Frontiers in Immunology, 14 art. 1194842. DOI: https://doi.org/10.3389/fimmu.2023.1194842
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2023 | Journal Article
CD28-signaling can be partially compensated in CD28-knockout mice but is essential for virus elimination in a murine model of multiple sclerosis
Hülskötter, K.; Lühder, F.; Leitzen, E.; Flügel, A. & Baumgärtner, W. (2023)
Frontiers in Immunology, 14 art. 1105432. DOI: https://doi.org/10.3389/fimmu.2023.1105432
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2023 | Journal Article
2-Methoxyestradiol-3,17-O,O-bis-sulfamate inhibits store-operated Ca2+ entry in T lymphocytes and prevents experimental autoimmune encephalomyelitis
Hosang, L.; Löhndorf, A.; Dohle, W.; Rosche, A.; Marry, S.; Diercks, B.-P. & Müller-Kirschbaum, L. C. et al. (2023)
Biochimica et Biophysica Acta. Molecular Cell Research, 1870(6) pp. 119485. DOI: https://doi.org/10.1016/j.bbamcr.2023.119485
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