Author Dittmann, Kai

• 2007 | Journal Article
  ​ ​SLP-65 signal transduction requires Src homology 2 domain-mediated membrane anchoring and a kinase-independent adaptor function of Syk​
  Abudula, A.; Grabbe, A.; Brechmann, M.; Polaschegg, C.; Herrmann, N.; Goldbeck, I. & Dittmann, K. et al.​ (2007) 
  Journal of Biological Chemistry, 282(39) pp. 29059​-29066​.​ DOI: https://doi.org/10.1074/jbc.M704043200 
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• 2007 | Review
  ​ ​Ca2+ signaling in antigen receptor-activated B lymphocytes​
  Engelke, M.; Engels, N.; Dittmann, K.; Stork, B.& Wienands, J. ​ (2007)
  Immunological Reviews, 218​ pp. 235​-246​.​
  Wiley-blackwell. DOI: https://doi.org/10.1111/j.1600-065X.2007.00539.x 
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• 2007 | Journal Article
  ​ ​The Hedgehog receptor Patched controls lymphoid lineage commitment​
  Uhmann, A.; Dittmann, K.; Nitzki, F.; Dressel, R.; Koleva, M.; Frommhold, A. & Zibat, A. et al.​ (2007) 
  Blood, 110(6) pp. 1814​-1823​.​ DOI: https://doi.org/10.1182/blood-2007-02-075648 
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• 2009 | Journal Article | Letter Note
  ​ ​Comment on "Direct Hematological Toxicity and Illegitimate Chromosomal Recombination Caused by the Systemic Activation of CreER(T2)"​
  Uhmann, A.; Dittmann, K.; Wienands, J.   & Hahn, H.​ (2009) 
  The Journal of Immunology, 183(5).​ DOI: https://doi.org/10.4049/jimmunol.0990063 
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• 2011 | Journal Article
  ​ ​T Cell Development Critically Depends on Prethymic Stromal Patched Expression​
  Uhmann, A.; van den Brandt, J.; Dittmann, K.; Hess, I.; Dressel, R.; Binder, C. & Luehder, F. et al.​ (2011) 
  The Journal of Immunology, 186(6) pp. 3383​-3391​.​ DOI: https://doi.org/10.4049/jimmunol.1001939 
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• 2011 | Journal Article | 
  ​ ​The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85​
  Oellerich, T.; Bremes, V.; Neumann, K.; Bohnenberger, H.; Dittmann, K.; Hsiao, H.-H. & Engelke, M. et al.​ (2011) 
  The EMBO Journal, 30(17) pp. 3620​-3634​.​ DOI: https://doi.org/10.1038/emboj.2011.251 
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• 2012 | Journal Article | 
  ​ ​PI3K Inhibition Enhances Doxorubicin-Induced Apoptosis in Sarcoma Cells​
  Marklein, D.; Graab, U.; Naumann, I.; Yan, T.; Ridzewski, R.; Nitzki, F. & Rosenberger, A.  et al.​ (2012) 
  PLoS ONE, 7(12) art. e52898​.​ DOI: https://doi.org/10.1371/journal.pone.0052898 
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• 2012 | Journal Article
  ​ ​Occurrence of acute lymphoblastic leukemia and juvenile myelomonocytic leukemia in a patient with Noonan syndrome carrying the germline PTPN11 mutation p.E139D​
  Pauli, S.; Steinemann, D.; Dittmann, K.; Wienands, J. ; Shoukier, M.; Moeschner, M. & Burfeind, P. et al.​ (2012) 
  American Journal of Medical Genetics Part A, 158A(3) pp. 652​-658​.​ DOI: https://doi.org/10.1002/ajmg.a.34439 
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• 2013 | Journal Article
  ​ ​The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain​
  Schneppenheim, J.; Dressel, R.; Huettl, S.; Luellmann-Rauch, R.; Engelke, M.; Dittmann, K. & Wienands, J.  et al.​ (2013) 
  Journal of Experimental Medicine, 210(1) pp. 41​-58​.​
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• 2013 | Journal Article
  ​ ​Empty liposomes induce antitumoral effects associated with macrophage responses distinct from those of the TLR1/2 agonist Pam(3)CSK(4) (BLP)​
  Koenig, S.; Regen, T.; Dittmann, K.; Engelke, M.; Wienands, J. ; Schwendener, R. & Hanisch, U.-K. et al.​ (2013) 
  Cancer Immunology Immunotherapy, 62(10) pp. 1587​-1597​.​ DOI: https://doi.org/10.1007/s00262-013-1444-4 
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• 2014 | Journal Article
  ​ ​The Intramembrane Proteases Signal Peptide Peptidase-Like 2a and 2b Have Distinct Functions In Vivo​
  Schneppenheim, J.; Huettl, S.; Mentrup, T.; Luellmann-Rauch, R.; Rothaug, M.; Engelke, M. & Dittmann, K. et al.​ (2014) 
  Molecular and Cellular Biology, 34(8) pp. 1398​-1411​.​ DOI: https://doi.org/10.1128/MCB.00038-14 
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• 2014 | Journal Article
  ​ ​DMBA/TPA Treatment Is Necessary for BCC Formation from Patched Deficient Epidermal Cells in Ptch(flox/flox)CD4Cre(+/-) Mice​
  Uhmann, A.; Hess, I.; Frommhold, A.; Koenig, S.; Zabel, S.; Nitzki, F. & Dittmann, K. et al.​ (2014) 
  Journal of Investigative Dermatology, 134(10) pp. 2620​-2629​.​ DOI: https://doi.org/10.1038/jid.2014.157 
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• 2014 | Journal Article | 
  ​ ​Depletion of Cutaneous Macrophages and Dendritic Cells Promotes Growth of Basal Cell Carcinoma in Mice​
  Koenig, S.; Nitzki, F.; Uhmann, A.; Dittmann, K.; Theiss-Suennemann, J.; Herrmann, M. & Reichardt, H. M. et al.​ (2014) 
  PLoS ONE, 9(4) art. e93555​.​ DOI: https://doi.org/10.1371/journal.pone.0093555 
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• 2014 | Journal Article
  ​ ​Inactivation of Patched1 in Murine Chondrocytes Causes Spinal Fusion Without Inflammation​
  Dittmann, K.; Wuelling, M.; Uhmann, A.; Dullin, C.; Hahn, H.; Schweyer, S. & Vortkamp, A. et al.​ (2014) 
  Arthritis & Rheumatology, 66(4) pp. 831​-840​.​ DOI: https://doi.org/10.1002/art.38325 
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• 2015 | Journal Article
  ​ ​Hedgehog Inhibitors in Rhabdomyosarcoma: A Comparison of Four Compounds and Responsiveness of Four Cell Lines​
  Ridzewski, R.; Rettberg, D.; Dittmann, K.; Cuvelier, N.; Fulda, S. & Hahn, H.​ (2015) 
  Frontiers in Oncology, 5.​ DOI: https://doi.org/10.3389/fonc.2015.00130 
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• 2015 | Journal Article | 
  ​ ​Reactivation of IgG-switched memory B cells by BCR-intrinsic signal amplification promotes IgG antibody production​
  Lutz, J.; Dittmann, K.; Boesl, M. R.; Winkler, T. H.; Wienands, J.   & Engels, N.​ (2015) 
  Nature Communications, 6 art. 8575​.​ DOI: https://doi.org/10.1038/ncomms9575 
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• 2015 | Journal Article
  ​ ​A Functional and Putative Physiological Role of Calcitriol in Patched1/Smoothened Interaction​
  Linder, B.; Weber, S.; Dittmann, K.; Adamski, J.; Hahn, H. & Uhmann, A.​ (2015) 
  Journal of Biological Chemistry, 290(32) pp. 19614​-19628​.​ DOI: https://doi.org/10.1074/jbc.M115.646141 
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• 2017 | Journal Article | 
  ​ ​LEF1 reduces tumor progression and induces myodifferentiation in a subset of rhabdomyosarcoma​
  Draeger, J.; Simon-Keller, K.; Pukrop, T.; Klemm, F.; Wilting, J.; Sticht, C. & Dittmann, K. et al.​ (2017) 
  Oncotarget, 8(2) pp. 3259​-3273​.​ DOI: https://doi.org/10.18632/oncotarget.13887 
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• 2018 | Journal Article | 
  ​ ​Different Response of Ptch Mutant and Ptch Wildtype Rhabdomyosarcoma Toward SMO and PI3K Inhibitors​
  Geyer, N.; Ridzewski, R.; Bauer, J.; Kuzyakova, M.; Dittmann, K.; Dullin, C. & Rosenberger, A.  et al.​ (2018) 
  Frontiers in Oncology, 8 art. 396​.​ DOI: https://doi.org/10.3389/fonc.2018.00396 
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