Author Cyganek, Lukas
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2017 | Conference Abstract
HUMAN CARDIOMYOCYTES DERIVED FROM INDUCED PLURIPOTENT STEM CELLS ARE TARGETS FOR ACTIVATED AUTOLOGOUS AND ALLOGENEIC NATURAL KILLER CELLS
Dressel, R.; Huebscher, D.; Monecke, S.; Elsner, L.; Borchert, T.; Cyganek, L. & Stauske, M. et al. (2017)
HLA, 89(6) pp. 343-344.
Hoboken: Wiley.
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2020 | Preprint
Local translation in synaptic mitochondria influences synaptic transmission
Yousefi, R.; Fornasiero, E. F.; Cyganek, L.; Jakobs, S. ; Rizzoli, S. O. ; Rehling, P. & Pacheu-Grau, D. (2020). DOI: https://doi.org/10.1101/2020.07.22.215194
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2021 | Journal Article
Effects of Antiarrhythmic Drugs on hERG Gating in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1
Huang, M.; Liao, Z.; Li, X.; Yang, Z.; Fan, X.; Li, Y. & Zhao, Z. et al. (2021)
Frontiers in Pharmacology, 12. DOI: https://doi.org/10.3389/fphar.2021.675003
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2021 | Journal Article
Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene‐edited human‐induced pluripotent stem cell‐derived cardiomyocytes and preclinical drug screening
El‐Battrawy, I.; Lan, H.; Cyganek, L.; Maywald, L.; Zhong, R.; Zhang, F. & Xu, Q. et al. (2021)
Clinical and Translational Medicine, 11(12). DOI: https://doi.org/10.1002/ctm2.646
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2021 | Book Chapter
Management of Metadata Types in Basic Cardiological Research
Kusch, H. ; Kossen, R. ; Suhr, M.; Freckmann, L.; Weber, L.; Henke, C.& Lehmann, C. et al. (2021)
In:Röhrig, Rainer; Beißbarth, Tim; König, Jochem; Ose, Claudia; Rauch, Geraldine; Sax, Ulrich; Schreiweis, Björn, et al. (Eds.), German Medical Data Sciences 2021: Digital Medicine: Recognize – Understand – Heal pp. 59-68. DOI: https://doi.org/10.3233/SHTI210542
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2021 | Journal Article | Research Paper |
Proteomic mapping of atrial and ventricular heart tissue in patients with aortic valve stenosis
Barbarics, B.; Eildermann, K.; Kaderali, L.; Cyganek, L.; Plessmann, U.; Bodemeyer, J. & Paul, T. et al. (2021)
Scientific Reports, 11(1) art. 24389. DOI: https://doi.org/10.1038/s41598-021-03907-3
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2022 | Journal Article
Transcriptional Effects of Candidate COVID-19 Treatments on Cardiac Myocytes
Jakobi, T.; Groß, J.; Cyganek, L. & Doroudgar, S. (2022)
Frontiers in Cardiovascular Medicine, 9 art. 844441. DOI: https://doi.org/10.3389/fcvm.2022.844441
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2022 | Journal Article
Dopamine D1/D5 Receptor Signaling Is Involved in Arrhythmogenesis in the Setting of Takotsubo Cardiomyopathy
Huang, M.; Yang, Z.; Li, Y.; Lan, H.; Cyganek, L.; Yuecel, G. & Lang, S. et al. (2022)
Frontiers in Cardiovascular Medicine, 8. DOI: https://doi.org/10.3389/fcvm.2021.777463
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2022 | Journal Article
Regulation of Ion Channel Function in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes by Cancer Cell Secretion Through DNA Methylation
Zhong, R.; Zhang, F.; Yang, Z.; Li, Y.; Xu, Q.; Lan, H. & Lang, S. et al. (2022)
Frontiers in Cardiovascular Medicine, 9. DOI: https://doi.org/10.3389/fcvm.2022.839104
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2022 | Journal Article
Krüppel-like factor 15 expression dynamics with CRISPR-based gene activation controls cardiomyocyte remodeling in the failing heart
Schoger, E.; Kim, R.; Priesmeier, L.; Bleckwedel, F.; Santos, G. L.; Lutz, S. & Cyganek, L. et al. (2022)
Journal of Molecular and Cellular Cardiology, 173 pp. 165. DOI: https://doi.org/10.1016/j.yjmcc.2022.08.325
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2022 | Journal Article |
Antiarrhythmic Effects of Vernakalant in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with Short QT Syndrome Type 1
Xu, Q.; Huang, X.; Meng, Z.; Li, Y.; Zhong, R.; Li, X. & Cyganek, L. et al. (2022)
Journal of Cardiovascular Development and Disease, 9(4) pp. 112. DOI: https://doi.org/10.3390/jcdd9040112
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2022 | Journal Article |
Biodegradable Poly-ε-Caprolactone Scaffolds with ECFCs and iMSCs for Tissue-Engineered Heart Valves
Lutter, G.; Puehler, T.; Cyganek, L.; Seiler, J.; Rogler, A.; Herberth, T. & Knueppel, P. et al. (2022)
International Journal of Molecular Sciences, 23(1) pp. 527. DOI: https://doi.org/10.3390/ijms23010527
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2022 | Journal Article | Research Paper |
Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures
Gönenc, I. I.; Wolff, A.; Schmidt, J.; Zibat, A.; Müller, C.; Cyganek, L. & Argyriou, L. et al. (2022)
Human Molecular Genetics,. DOI: https://doi.org/10.1093/hmg/ddab373
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2023 | Journal Article
Novel insights in the pathomechanism of Brugada syndrome and fever‐related type 1 ECG changes in a preclinical study using human‐induced pluripotent stem cell‐derived cardiomyocytes
Li, Y.; Dinkel, H.; Pakalniskyte, D.; Busley, A. V.; Cyganek, L.; Zhong, R. & Zhang, F. et al. (2023)
Clinical and Translational Medicine, 13(3) art. e1130. DOI: https://doi.org/10.1002/ctm2.1130
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2023 | Journal Article
Flagellin-Induced Immune Response in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Yuecel, G.; Zhou, X.; Terkatz, L.; Wendel, A.; Reinhardt, J.; El-Battrawy, I. & Sattler, K. et al. (2023)
International Journal of Molecular Sciences, 24(18) art. 13933. DOI: https://doi.org/10.3390/ijms241813933
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2023 | Journal Article
Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V
Busley, A. V. & Cyganek, L. (2023)
Stem Cell Research, 69 art. 103108. DOI: https://doi.org/10.1016/j.scr.2023.103108
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2023 | Journal Article
Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V
Busley, A. V.; Kleinsorge, M. & Cyganek, L. (2023)
Stem Cell Research, 69 art. 103105. DOI: https://doi.org/10.1016/j.scr.2023.103105
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2023 | Journal Article |
Metabolic switch from fatty acid oxidation to glycolysis in knock‐in mouse model of Barth syndrome
Chowdhury, A.; Boshnakovska, A.; Aich, A.; Methi, A.; Vergel Leon, A. M.; Silbern, I. & Lüchtenborg, C. et al. (2023)
EMBO Molecular Medicine, art. e17399. DOI: https://doi.org/10.15252/emmm.202317399
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2023 | Preprint
Secreted-Frizzled-Related Protein 5 Modulates Calcium Handling in Human Ipsc-Cardiomyocytes
Weber, F.; Klas, S.; Hindmarsh, V.; Salinas, G.; Toischer, K.; Hasenfuss, G.& Cyganek, L. (2023). DOI: https://doi.org/10.2139/ssrn.4544232
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2023 | Journal Article |
Combining a tetracycline (Tet)-inducible gRNA system and CRISPRa for titratable and timely controlled enhancement of endogenous SHISA3 activation in human induced pluripotent stem cells (hiPSC)
Priesmeier, L.; Schoger, E.; Cyganek, L. & Zelarayán, L. C. (2023)
Stem Cell Research, 71 pp. 103163. DOI: https://doi.org/10.1016/j.scr.2023.103163
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