Author Brockmöller, Jürgen

• 2002 | Journal Article
  ​ ​Validity of PCR with emphasis on variable number of tandem repeat analysis​
  Kaiser, R.; Tremblay, P.-B.; Roots, I. & Brockmöller, J.​ (2002) 
  Clinical Biochemistry, 35(1) art. PII S0009-9120(02)00273-4​.​ DOI: https://doi.org/10.1016/S0009-9120(02)00273-4 
  ​Details  DOI  PMID  PMC  WoS 

• 2007 | Journal Article
  ​ ​Genetic polymorphisms in the amino acid transporters LAT1 and LAT2 in relation to the pharmacokinetics and side effects of melphalan​
  Kühne, A.; Kaiser, R.; Schirmer, M.; Heider, U.; Muhlke, S.; Niere, W. & Overbeck, T. et al.​ (2007) 
  Pharmacogenetics and Genomics, 17(7) pp. 505​-517​.​ DOI: https://doi.org/10.1097/FPC.0b013e3280ea77cd 
  ​Details  DOI  PMID  PMC  WoS 

• 2010 | Journal Article | 
  ​ ​CYP2D6 and CYP2C19 in Papua New Guinea: High frequency of previously uncharacterized CYP2D6 alleles and heterozygote excess.​
  von Ahsen, N.; Tzvetkov, M.; Karunajeewa, H. A.; Gomorrai, S.; Ura, A.; Brockmöller, J. & Davis, T. M. E. et al.​ (2010) 
  International journal of molecular epidemiology and genetics, 1(4) pp. 310​-9​.​
  ​Details  PMID  PMC 

• 2020 | Journal Article
  ​ ​Differences in Metformin and Thiamine Uptake between Human and Mouse Organic Cation Transporter 1: Structural Determinants and Potential Consequences for Intrahepatic Concentrations​
  Meyer, M. J.; Tuerkova, A.; Römer, S.; Wenzel, C.; Seitz, T.; Gaedcke, J. & Oswald, S. et al.​ (2020) 
  Drug Metabolism and Disposition, 48(12) pp. 1380​-1392​.​ DOI: https://doi.org/10.1124/dmd.120.000170 
  ​Details  DOI 

• 2021 | Journal Article
  ​ ​How do psychostimulants enter the human brain? Analysis of the role of the proton-organic cation antiporter​
  Sachkova, A.; Doetsch, D. A.; Jensen, O.; Brockmöller, J. & Ansari, S.​ (2021) 
  Biochemical Pharmacology, art. S0006295221003671​.​ DOI: https://doi.org/10.1016/j.bcp.2021.114751 
  ​Details  DOI 

• 2021 | Journal Article
  ​ ​The roles of caffeine and corticosteroids in modulating cortical excitability after paired associative stimulation (PAS) and transcranial alternating current stimulation (tACS) in caffeine-naïve and caffeine-adapted subjects​
  Zulkifly, M. F. M.; Merkohitaj, O.; Paulus, W. & Brockmöller, J.​ (2021) 
  Psychoneuroendocrinology, 127 pp. 105201​.​ DOI: https://doi.org/10.1016/j.psyneuen.2021.105201 
  ​Details  DOI 

• 2021 | Journal Article | Research Paper | 
  ​ ​Isobutyrylcarnitine as a Biomarker of OCT1 Activity and Interspecies Differences in its Membrane Transport​
  Jensen, O.; Matthaei, J.; Klemp, H. G.; Meyer, M. J.; Brockmöller, J. & Tzvetkov, M. V.​ (2021) 
  Frontiers in Pharmacology, 12.​ DOI: https://doi.org/10.3389/fphar.2021.674559 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​8-Oxoguanine DNA Glycosylase (OGG1) Cys326 Variant: Increased Risk for Worse Outcome of Patients with Locally Advanced Rectal Cancer after Multimodal Therapy​
  Leu, M.; Riebeling, T.; Dröge, L. H.; Hubert, L.; Guhlich, M.; Wolff, H. A. & Brockmöller, J. et al.​ (2021) 
  Cancers, 13(11) pp. 2805​.​ DOI: https://doi.org/10.3390/cancers13112805 
  ​Details  DOI 

• 2021 | Journal Article | 
  ​ ​CYP2B6 Functional Variability in Drug Metabolism and Exposure Across Populations—Implication for Drug Safety, Dosing, and Individualized Therapy​
  Langmia, I. M.; Just, K. S.; Yamoune, S.; Brockmöller, J.; Masimirembwa, C. & Stingl, J. C.​ (2021) 
  Frontiers in Genetics, 12.​ DOI: https://doi.org/10.3389/fgene.2021.692234 
  ​Details  DOI 

• 2021 | Journal Article | Research Paper | 
  ​ ​Overlap and Specificity in the Substrate Spectra of Human Monoamine Transporters and Organic Cation Transporters 1, 2, and 3​
  Gebauer, L.; Jensen, O.; Neif, M.; Brockmöller, J. & Dücker, C.​ (2021) 
  International Journal of Molecular Sciences, 22(23) art. 12816​.​ DOI: https://doi.org/10.3390/ijms222312816 
  ​Details  DOI 

• 2021 | Journal Article | Research Paper | 
  ​ ​Effects of Genetic Polymorphism in CYP2D6, CYP2C19, and the Organic Cation Transporter OCT1 on Amitriptyline Pharmacokinetics in Healthy Volunteers and Depressive Disorder Patients​
  Steimer, W.; Pischa, K.; Leucht, S.; Kullmann, M.; Ouethy, T.; Rafehi, M.   & Matthaei, J. et al.​ (2021) 
  Frontiers in Pharmacology, 12.​ DOI: https://doi.org/10.3389/fphar.2021.688950 
  ​Details  DOI 

• 2021 | Journal Article
  ​ ​Confounding effects of caffeine on neuroplasticity induced by transcranial alternating current stimulation and paired associative stimulation​
  Zulkifly, M. F. M.; Merkohitaj, O.; Brockmöller, J. & Paulus, W.​ (2021) 
  Clinical Neurophysiology, 132(6) pp. 1367​-1379​.​ DOI: https://doi.org/10.1016/j.clinph.2021.01.024 
  ​Details  DOI 

• 2022 | Journal Article
  ​ ​Amino acids in transmembrane helix 1 confer major functional differences between human and mouse orthologs of the polyspecific membrane transporter OCT1​
  Meyer, M. J.; Schreier, P. C.; Basaran, M.; Vlasova, S.; Seitz, T.; Brockmöller, J. & Zdrazil, B. et al.​ (2022) 
  Journal of Biological Chemistry, art. S0021925822004148​.​ DOI: https://doi.org/10.1016/j.jbc.2022.101974 
  ​Details  DOI 

• 2022 | Journal Article
  ​ ​Molecular basis for stereoselective transport of fenoterol by the organic cation transporters 1 and 2​
  Gebauer, L.; Arul Murugan, N.; Jensen, O.; Brockmöller, J. & Rafehi, M.​ (2022) 
  Biochemical Pharmacology, 197 art. S0006295221004974​.​ DOI: https://doi.org/10.1016/j.bcp.2021.114871 
  ​Details  DOI 

• 2022 | Journal Article | 
  ​ ​Stereoselectivity in the Membrane Transport of Phenylethylamine Derivatives by Human Monoamine Transporters and Organic Cation Transporters 1, 2, and 3​
  Gebauer, L.; Rafehi, M. & Brockmöller, J.​ (2022) 
  Biomolecules, 12(10) pp. 1507​.​ DOI: https://doi.org/10.3390/biom12101507 
  ​Details  DOI 

• 2022 | Journal Article | 
  ​ ​Atypical Substrates of the Organic Cation Transporter 1​
  Redeker, K. Redeker, Kyra-Elisa Maria; Jensen, O.; Gebauer, L.; Meyer-Tönnies, M. J. & Brockmöller, J.​ (2022) 
  Biomolecules, 12(11) pp. 1664​.​ DOI: https://doi.org/10.3390/biom12111664 
  ​Details  DOI 

• 2023 | Journal Article | 
  ​ ​Combined and independent effects of OCT1 and CYP2D6 on the cellular disposition of drugs​
  Gebauer, L.; Dücker, C.; Jensen, O. & Brockmöller, J.​ (2023) 
  Biomedicine & Pharmacotherapy, 161 art. 114454​.​ DOI: https://doi.org/10.1016/j.biopha.2023.114454 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Stereoselective Inhibition of High- and Low-Affinity Organic Cation Transporters​
  Gebauer, L.; Jensen, O.; Rafehi, M. & Brockmöller, J.​ (2023) 
  Molecular Pharmaceutics, art. acs.molpharmaceut.3c00691​.​ DOI: https://doi.org/10.1021/acs.molpharmaceut.3c00691 
  ​Details  DOI 

• 2023 | Journal Article
  ​ ​Stereoselectivity in Cell Uptake by SLC22 Organic Cation Transporters 1, 2, and 3​
  Gebauer, L.; Jensen, O.; Rafehi, M. & Brockmöller, J.​ (2023) 
  Journal of Medicinal Chemistry, 66(23) pp. 15990​-16001​.​ DOI: https://doi.org/10.1021/acs.jmedchem.3c01436 
  ​Details  DOI 

• 2023 | Journal Article | 
  ​ ​Oral Drug Absorption and Drug Disposition in Critically Ill Cardiac Patients​
  Harnisch, L.-O. ; Brockmöller, J.; Hapke, A.; Sindern, J.; Bruns, E.; Evertz, R. & Toischer, K. et al.​ (2023) 
  Pharmaceutics, 15(11) pp. 2598​.​ DOI: https://doi.org/10.3390/pharmaceutics15112598 
  ​Details  DOI 

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