Author Brhane, Yonathan

• 2015 | Journal Article
  ​ ​Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer​
  Hung, R. J.; Ulrich, C. M.; Goode, E. L.; Brhane, Y.; Muir, K.; Chan, A. T. & Le Marchand, L. et al.​ (2015) 
  JNCI Journal of the National Cancer Institute, 107(11) art. djv246​.​ DOI: https://doi.org/10.1093/jnci/djv246 
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• 2015 | Journal Article
  ​ ​Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia​
  Brenner, D. R.; Amos, C. I.; Brhane, Y.; Timofeeva, M. N.; Caporaso, N.; Wang, Y. & Christiani, D. C. et al.​ (2015) 
  Carcinogenesis, 36(11) pp. 1314​-1326​.​ DOI: https://doi.org/10.1093/carcin/bgv128 
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• 2015 | Journal Article
  ​ ​Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions​
  Qian, D. C.; Byun, J.; Han, Y.; Greene, C. S.; Field, J. K.; Hung, R. J. & Brhane, Y. et al.​ (2015) 
  Human Molecular Genetics, 24(25) pp. 7406​-7420​.​ DOI: https://doi.org/10.1093/hmg/ddv440 
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• 2016 | Journal Article | 
  ​ ​A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer​
  Yuan, H.; Liu, H.; Liu, Z.; Owzar, K.; Han, Y.; Su, L. I. & Wei, Y. et al.​ (2016) 
  Scientific Reports, 6 art. 34234​.​ DOI: https://doi.org/10.1038/srep34234 
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• 2016 | Journal Article
  ​ ​Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14 463 cases and 44 188 controls​
  Kang, X.; Liu, H.; Onaitis, M. W.; Liu, Z.; Owzar, K.; Han, Y. & Su, L. I. et al.​ (2016) 
  Carcinogenesis, 37(3) pp. 280​-289​.​ DOI: https://doi.org/10.1093/carcin/bgw014 
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• 2017 | Journal Article | 
  ​ ​Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium​
  Feng, Y.; Wang, Y.; Liu, H.; Liu, Z.; Mills, C.; Han, Y. & Hung, R. J. et al.​ (2017) 
  Scientific Reports, 7 art. 825​.​ DOI: https://doi.org/10.1038/s41598-017-00850-0 
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• 2017 | Journal Article
  ​ ​Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus​
  Yin, J.; Liu, H.; Liu, Z.; Owzar, K.; Han, Y.; Su, L. I. & Wei, Y. et al.​ (2017) 
  Molecular Carcinogenesis, 56(6) pp. 1663​-1672​.​ DOI: https://doi.org/10.1002/mc.22622 
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• 2017 | Journal Article
  ​ ​Susceptibility Loci of CNOT6 in the General mRNA Degradation Pathway and Lung Cancer Risk-A Re-Analysis of Eight GWASs​
  Zhou, F.; Wang, Y.; Liu, H.; Ready, N.; Han, Y.; Hung, R. J. & Brhane, Y. et al.​ (2017) 
  Molecular Carcinogenesis, 56(4) pp. 1227​-1238​.​ DOI: https://doi.org/10.1002/mc.22585 
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• 2017 | Journal Article
  ​ ​Functional variants in DCAF4 associated with lung cancer risk in European populations​
  Liu, H.; Liu, Z.; Wang, Y.; Stinchcombe, T. E.; Owzar, K.; Han, Y. & Hung, R. J. et al.​ (2017) 
  Carcinogenesis, 38(5) pp. 541​-551​.​ DOI: https://doi.org/10.1093/carcin/bgx033 
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• 2017 | Journal Article | 
  ​ ​Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs​
  Pan, Y.; Liu, H.; Wang, Y.; Kang, X.; Liu, Z.; Owzar, K. & Han, Y. et al.​ (2017) 
  Scientific Reports, 7 art. 44634​.​ DOI: https://doi.org/10.1038/srep44634 
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• 2019 | Journal Article | 
  ​ ​Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region​
  Hung, R. J.; Spitz, M. R.; Houlston, R. S.; Schwartz, A. G.; Field, J. K.; Ying, J. & Li, Y. et al.​ (2019) 
  Journal of Thoracic Oncology, 14(8) pp. 1360​-1369​.​ DOI: https://doi.org/10.1016/j.jtho.2019.04.008 
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• 2019 | Journal Article
  ​ ​Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis​
  Zhu, Y.; Wei, Y.; Zhang, R.; Dong, X.; Shen, S.; Zhao, Y. & Bai, J. et al.​ (2019) 
  Cancer Epidemiology, Biomarkers & Prevention, 28(5) pp. 935​-942​.​ DOI: https://doi.org/10.1158/1055-9965.EPI-18-0356 
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• 2020 | Journal Article | 
  ​ ​Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility​
  Kachuri, L.; Johansson, M.; Rashkin, S. R.; Graff, R. E.; Bossé, Y.; Manem, V. & Caporaso, N. E. et al.​ (2020) 
  Nature Communications, 11(1).​ DOI: https://doi.org/10.1038/s41467-019-13855-2 
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• 2021 | Journal Article
  ​ ​Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model​
  Hung, R. J.; Warkentin, M. T.; Brhane, Y.; Chatterjee, N.; Christiani, D. C.; Landi, M. T. & Caporaso, N. E. et al.​ (2021) 
  Cancer Research, 81(6) pp. 1607​-1615​.​ DOI: https://doi.org/10.1158/0008-5472.CAN-20-1237 
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• 2022 | Journal Article | 
  ​ ​Deciphering associations between three RNA splicing-related genetic variants and lung cancer risk​
  Yang, W.; Liu, H.; Zhang, R.; Freedman, J. A.; Han, Y.; Hung, R. J. & Brhane, Y. et al.​ (2022) 
  npj Precision Oncology, 6(1).​ DOI: https://doi.org/10.1038/s41698-022-00281-9 
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