Author Benda, Norbert
-
2010 | Journal Article
Aspects of Modernizing Drug Development Using Clinical Scenario Planning and Evaluation
Benda, N.; Branson, M.; Maurer, W. & Friede, T. (2010)
DRUG INFORMATION JOURNAL, 44(3) pp. 299-315.
Details WoS
-
2010 | Journal Article
Perspectives on the Use of Adaptive Designs in Clinical Trials. Part II. Panel Discussion
Benda, N.; Brannath, W.; Bretz, F.; Burger, H.-U.; Friede, T.; Maurer, W. & Wang, S. (2010)
Journal of Biopharmaceutical Statistics, 20(6) art. PII 929076459. DOI: https://doi.org/10.1080/10543406.2010.514447
Details DOI PMID PMC WoS
-
2014 | Journal Article |
Spline-based procedures for dose-finding studies with active control
Helms, H.-J.; Benda, N.; Zinserling, J.; Kneib, T. & Friede, T. (2014)
Statistics in Medicine, 34(2) pp. 232-248. DOI: https://doi.org/10.1002/sim.6320
Details DOI PMID PMC
-
2015 | Journal Article |
POINT AND INTERVAL ESTIMATORS OF THE TARGET DOSE IN CLINICAL DOSE-FINDING STUDIES WITH ACTIVE CONTROL
Helms, H.-J.; Benda, N. & Friede, T. (2015)
Journal of Biopharmaceutical Statistics, 25(5) pp. 939-957. DOI: https://doi.org/10.1080/10543406.2014.920343
Details DOI PMID PMC WoS
-
2016 | Review |
Systematic reviews in paediatric multiple sclerosis and Creutzfeldt-Jakob disease exemplify shortcomings in methods used to evaluate therapies in rare conditions
Unkel, S.; Roever, C. ; Stallard, N.; Benda, N.; Posch, M.; Zohar, S.& Friede, T. (2016)
Orphanet Journal of Rare Diseases, 11.
Biomed Central Ltd. DOI: https://doi.org/10.1186/s13023-016-0402-6
Details DOI PMID PMC WoS
-
2018 | Journal Article |
Recent advances in methodology for clinical trials in small populations: the InSPiRe project.
Friede, T. ; Posch, M.; Zohar, S.; Alberti, C.; Benda, N.; Comets, E. & Day, S. et al. (2018)
Orphanet Journal of Rare Diseases, 13 art. 186. DOI: https://doi.org/10.1186/s13023-018-0919-y
Details DOI PMID PMC
-
2018 | Journal Article |
On estimands and the analysis of adverse events in the presence of varying follow‐up times within the benefit assessment of therapies
Unkel, S.; Amiri, M.; Benda, N.; Beyersmann, J.; Knoerzer, D.; Kupas, K. & Langer, F. et al. (2018)
Pharmaceutical Statistics, 18(2) pp. 166-183. DOI: https://doi.org/10.1002/pst.1915
Details DOI PMID PMC
-
2019 | Journal Article |
Adaptive trial designs in diagnostic accuracy research
Zapf, A.; Stark, M.; Gerke, O.; Ehret, C.; Benda, N.; Bossuyt, P. & Deeks, J. et al. (2019)
Statistics in Medicine, 39(5) pp. 591-601. DOI: https://doi.org/10.1002/sim.8430
Details DOI
-
2019 | Journal Article |
A comparison of subgroup identification methods in clinical drug development: Simulation study and regulatory considerations
Huber, C.; Benda, N. & Friede, T. (2019)
Pharmaceutical Statistics, 18(5) pp. 600-626. DOI: https://doi.org/10.1002/pst.1951
Details DOI PMID PMC
-
2020 | Journal Article
Effect size estimates from umbrella designs: Handling patients with a positive test result for multiple biomarkers using random or pragmatic subtrial allocation
Kesselmeier, M.; Benda, N. & Scherag, A. (2020)
PLoS One, 15(8) pp. e0237441. DOI: https://doi.org/10.1371/journal.pone.0237441
Details DOI
-
2020 | Journal Article
Enrichment designs using placebo nonresponders
Benda, N. & Haenisch, B. (2020)
Pharmaceutical Statistics, 19(3) pp. 303-314. DOI: https://doi.org/10.1002/pst.1992
Details DOI
-
2020 | Journal Article
Efficient Adaptive Designs for Clinical Trials of Interventions for COVID-19
Stallard, N.; Hampson, L.; Benda, N.; Brannath, W.; Burnett, T.; Friede, T. & Kimani, P. K. et al. (2020)
Statistics in Biopharmaceutical Research, 12(4) pp. 483-497. DOI: https://doi.org/10.1080/19466315.2020.1790415
Details DOI
-
2020 | Journal Article
Blinded continuous information monitoring of recurrent event endpoints with time trends in clinical trials
Mütze, T. ; Salem, S.; Benda, N.; Schmidli, H. & Friede, T. (2020)
Statistics in Medicine, 39(27) pp. 3968-3985. DOI: https://doi.org/10.1002/sim.8702
Details DOI
-
2020 | Journal Article |
Optimal Design in Hierarchical Random Effect Models for Individual Prediction with Application in Precision Medicine
Prus, M.; Benda, N. & Schwabe, R. (2020)
Journal of Statistical Theory and Practice, 14(2). DOI: https://doi.org/10.1007/s42519-020-00090-y
Details DOI
-
2021 | Journal Article | Erratum
Correction to: Optimal Design in Hierarchical Random Effect Models for Individual Prediction with Application in Precision Medicine
Prus, M.; Benda, N. & Schwabe, R. (2021)
Journal of Statistical Theory and Practice, 15(3). DOI: https://doi.org/10.1007/s42519-021-00205-z
Details DOI
-
2021 | Journal Article |
Subgroup identification in individual participant data meta-analysis using model-based recursive partitioning
Huber, C.; Benda, N. & Friede, T. (2021)
Advances in Data Analysis and Classification, 16(3) pp. 797-815. DOI: https://doi.org/10.1007/s11634-021-00458-3
Details DOI
-
2021 | Journal Article | Research Paper |
Classification of Companion Diagnostics: A New Framework for Biomarker-Driven Patient Selection
Huber, C.; Friede, T.; Stingl, J. & Benda, N. (2021)
Therapeutic Innovation & Regulatory Science, 56(2) pp. 244-254. DOI: https://doi.org/10.1007/s43441-021-00352-2
Details DOI