Author Akula, Nirmala

• 2010 | Journal Article | 
  ​ ​The International Consortium on Lithium Genetics (ConLiGen): An Initiative by the NIMH and IGSLI to Study the Genetic Basis of Response to Lithium Treatment​
  Schulze, T. G.; Alda, M.; Adli, M.; Akula, N.; Ardau, R.; Bui, E. T. & Chillotti, C. et al.​ (2010) 
  Neuropsychobiology, 62(1) pp. 72​-78​.​ DOI: https://doi.org/10.1159/000314708 
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• 2011 | Journal Article | Letter Note | 
  ​ ​Replication of association of 3p21.1 with susceptibility to bipolar disorder but not major depression Reply​
  McMahon, F. J.; Akula, N.; Cichon, S.; Detera-Wadleigh, S. D.; Edenberg, H. J.; Holsboer, F. & Noethen, M. M. et al.​ (2011) 
  Nature Genetics, 43(1).​ DOI: https://doi.org/10.1038/ng0111-5 
  ​Details  DOI  WoS 

• 2011 | Journal Article | 
  ​ ​Accuracy of CNV Detection from GWAS Data​
  Zhang, D.; Qian, Y.; Akula, N.; Alliey-Rodriguez, N.; Tang, J.; Gershon, E. S. & Liu, C.​ (2011) 
  PLoS ONE, 6(1) art. e14511​.​ DOI: https://doi.org/10.1371/journal.pone.0014511 
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• 2012 | Journal Article
  ​ ​Interaction networks of lithium and valproate molecular targets reveal a striking enrichment of apoptosis functional clusters and neurotrophin signaling​
  Gupta, A.; Schulze, T. G.; Nagarajan, V.; Akula, N.; Corona, W.; Jiang, X.-Y. & Hunter, N. et al.​ (2012) 
  The Pharmacogenomics Journal, 12(4) pp. 328​-341​.​ DOI: https://doi.org/10.1038/tpj.2011.9 
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• 2013 | Journal Article | 
  ​ ​Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report​
  Manchia, M.; Adli, M.; Akula, N.; Ardau, R.; Aubry, J.-M.; Backlund, L. & Banzato, C. E. M. et al.​ (2013) 
  PLoS ONE, 8(6) art. e65636​.​ DOI: https://doi.org/10.1371/journal.pone.0065636 
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• 2013 | Journal Article
  ​ ​Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder​
  Chen, D. T. W.; Jiang, X.; Akula, N.; Shugart, Y. Y.; Wendland, J. R.; Steele, C. J. M. & Kassem, L. et al.​ (2013) 
  Molecular Psychiatry, 18(2) pp. 195​-205​.​ DOI: https://doi.org/10.1038/mp.2011.157 
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• 2014 | Journal Article
  ​ ​Molecular genetic overlap in bipolar disorder, schizophrenia, and major depressive disorder​
  Schulze, T. G.; Akula, N.; Breuer, R.; Steele, J. O.; Nalls, M. A.; Singleton, A. B. & Degenhardt, F. A. et al.​ (2014) 
  The World Journal of Biological Psychiatry, 15(3) pp. 200​-208​.​ DOI: https://doi.org/10.3109/15622975.2012.662282 
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• 2016 | Journal Article
  ​ ​Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study​
  Hou, L.; Heilbronner, U. ; Degenhardt, F.; Adli, M.; Akiyama, K.; Akula, N. & Ardau, R. et al.​ (2016) 
  The Lancet, 387(10023) pp. 1085​-1093​.​ DOI: https://doi.org/10.1016/S0140-6736(16)00143-4 
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• 2016 | Journal Article
  ​ ​Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder​
  Hou, L.; Bergen, S. E.; Akula, N.; Song, J.; Hultman, C. M.; Landén, M. & Adli, M. et al.​ (2016) 
  Human Molecular Genetics, 25(15) pp. 3383​-3394​.​ DOI: https://doi.org/10.1093/hmg/ddw181 
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• 2019 | Journal Article | 
  ​ ​Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study​
  Kalman, J. L.; Papiol, S.; Forstner, A. J.; Heilbronner, U.; Degenhardt, F.; Strohmaier, J. & Adli, M. et al.​ (2019) 
  Bipolar Disorders, 21(1) pp. 68​-75​.​ DOI: https://doi.org/10.1111/bdi.12659 
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• 2021 | Journal Article
  ​ ​Association of Attention-Deficit/Hyperactivity Disorder and Depression Polygenic Scores with Lithium Response: A Consortium for Lithium Genetics Study​
  Coombes, B. J.; Millischer, V.; Batzler, A.; Larrabee, B.; Hou, L.; Papiol, S. & Heilbronner, U. et al.​ (2021) 
  Complex Psychiatry, 7(3-4) pp. 80​-89​.​ DOI: https://doi.org/10.1159/000519707 
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• 2021 | Journal Article | 
  ​ ​Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients​
  Schubert, K. O.; Thalamuthu, A.; Amare, A. T.; Frank, J.; Streit, F.; Adl, M. & Akula, N. et al.​ (2021) 
  Translational Psychiatry, 11(1) art. 606​.​ DOI: https://doi.org/10.1038/s41398-021-01702-2 
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• 2022 | Journal Article
  ​ ​Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach​
  Cearns, M.; Amare, A. T.; Schubert, K. O.; Thalamuthu, A.; Frank, J.; Streit, F. & Adli, M. et al.​ (2022) 
  The British Journal of Psychiatry, 220(4) pp. 219​-228​.​ DOI: https://doi.org/10.1192/bjp.2022.28 
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• 2022 | Journal Article | Erratum | 
  ​ ​Correction: Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients​
  Schubert, K. O.; Thalamuthu, A.; Amare, A. T.; Frank, J.; Streit, F.; Adl, M. & Akula, N. et al.​ (2022) 
  Translational Psychiatry, 12(1).​ DOI: https://doi.org/10.1038/s41398-022-02037-2 
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• 2024 | Journal Article
  ​ ​Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study​
  Ou, A. H.; Rosenthal, S. B.; Adli, M.; Akiyama, K.; Akula, N.; Alda, M. & Amare, A. T. et al.​ (2024) 
  Translational Psychiatry, 14(1).​ DOI: https://doi.org/10.1038/s41398-024-02811-4 
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