Author Zafar, Saima
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2011 | Journal Article
Proteomics Approach to Identify the Interacting Partners of Cellular Prion Protein and Characterization of Rab7a Interaction in Neuronal Cells
Zafar, S.; von Ahsen, N.; Oellerich, M.; Zerr, I.; Schulz-Schaeffer, W. J.; Armstrong, V. W. & Asif, A. R. (2011)
Journal of Proteome Research, 10(7) pp. 3123-3135. DOI: https://doi.org/10.1021/pr2001989
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2012 | Conference Abstract
Interactive role of Arf1 and Alpha tubulin-1 protein during the intracellular transportation of PrPc
Zafar, S. (2012)
Prion, 6
Austin: Landes Bioscience.
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2013 | Conference Abstract
Analysis of sporadic Creutzfeldt-Jakob disease patients cerebrospinal fluid by real-time quaking-induced conversion
Cramm, M.; Schmitz, M.; Karch, A.; Zafar, S.; Schroeder, B.; Raeber, A. & Kuhn, F. et al. (2013)
Prion, 7 pp. 54-55.
Austin: Landes Bioscience.
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2013 | Journal Article
PrP mRNA and protein expression in brain and PrPc in CSF in Creutzfeldt-Jakob disease MM1 and VV2
Llorens, F.; Ansoleaga, B.; Garcia-Esparcia, P.; Zafar, S.; Grau-Rivera, O.; Lopez-Gonzalez, I. & Blanco, R. et al. (2013)
Prion, 7(5) pp. 383-393. DOI: https://doi.org/10.4161/pri.26416
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2014 | Conference Abstract
Subtype and regional regulation of prion biomarkers in sporadic Creutzfeldt-Jakob disease
Llorens, F.; Zafar, S.; Ansoleaga, B.; Shafiq, M. ; Blanco, R.; Carmona, M. & Gelpi, E. et al. (2014)
Prion, 8
Austin: Landes Bioscience.
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2014 | Journal Article
Behavioral abnormalities in prion protein knockout mice and the potential relevance of PrPC for the cytoskeleton
Schmitz, M.; Zafar, S.; Silva, C. J. & Zerr, I. (2014)
Prion, 8(6) pp. 381-386. DOI: https://doi.org/10.4161/19336896.2014.983746
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2014 | Journal Article |
Subtype and regional-specific neuroinflammation in sporadic Creutzfeldt-Jakob disease
Llorens, F.; Lopez-Gonzalez, I.; Thuene, K.; Carmona, M.; Zafar, S.; Andreoletti, O. & Zerr, I. et al. (2014)
Frontiers in Aging Neuroscience, 6 art. 198. DOI: https://doi.org/10.3389/fnagi.2014.00198
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2014 | Journal Article
Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease
Douet, J. Y.; Zafar, S.; Perret-Liaudet, A.; Lacroux, C.; Lugan, S.; Aron, N. & Cassard, H. et al. (2014)
EMERGING INFECTIOUS DISEASES, 20(1) pp. 114-117. DOI: https://doi.org/10.3201/eid2001.130353
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2014 | Journal Article
Association of prion protein genotype and scrapie prion protein type with cellular prion protein charge isoform profiles in cerebrospinal fluid of humans with sporadic or familial prion diseases
Schmitz, M.; Luellmann, K.; Zafar, S.; Ebert, E.; Wohlhage, M.; Oikonomou, P. & Schlomm, M. et al. (2014)
Neurobiology of Aging, 35(5) pp. 1177-1188. DOI: https://doi.org/10.1016/j.neurobiolaging.2013.11.010
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2015 | Journal Article
Quantification of CSF biomarkers using an electrochemiluminescence-based detection system in the differential diagnosis of AD and sCJD
Llorens, F.; Kruse, N.; Schmitz, M.; Shafiq, M.; Gomes da Cunha, J. E.; Gotzman, N. & Zafar, S. et al. (2015)
Journal of Neurology, 262(10) pp. 2305-2311. DOI: https://doi.org/10.1007/s00415-015-7837-x
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2015 | Journal Article
Application of capillary immunoelectrophoresis revealed an age- and gender-dependent regulated expression of PrPC in liver
Arora, A. S. ; Zafar, S.; Kollmar, O.; Llorens, F.; Tahir, W.; Vanselow, S. & Kumar, P. et al. (2015)
Electrophoresis, 36(24) pp. 3026-3033. DOI: https://doi.org/10.1002/elps.201500244
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2015 | Journal Article
Creutzfeldt-Jakob Disease Subtype-Specific Regional and Temporal Regulation of ADP Ribosylation Factor-1-Dependent Rho/MLC Pathway at Pre-Clinical Stage
Zafar, S.; Schmitz, M.; Younus, N.; Tahir, W.; Shafiq, M.; Llorens, F. & Ferrer, I. et al. (2015)
Journal of Molecular Neuroscience, 56(2) pp. 329-348. DOI: https://doi.org/10.1007/s12031-015-0544-3
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2015 | Journal Article
Cellular prion protein directly interacts with and enhances lactate dehydrogenase expression under hypoxic conditions
Ramljak, S.; Schmitz, M.; Zafar, S.; Wrede, A.; Schenkel, S.; Asif, A. R. & Carimalo, J. et al. (2015)
Experimental Neurology, 271 pp. 155-167. DOI: https://doi.org/10.1016/j.expneurol.2015.04.025
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2015 | Journal Article
Cytokine profiles and the role of cellular prion protein in patients with vascular dementia and vascular encephalopathy
Schmitz, M.; Hermann, P.; Oikonomou, P.; Stoeck, K.; Ebert, E.; Poliakova, T. & Schmidt, C. D. et al. (2015)
Neurobiology of Aging, 36(9) pp. 2597-2606. DOI: https://doi.org/10.1016/j.neurobiolaging.2015.05.013
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2015 | Journal Article |
Characteristic CSF Prion Seeding Efficiency in Humans with Prion Diseases
Cramm, M.; Schmitz, M.; Karch, A.; Zafar, S.; Varges, D. A.; Mitrova, E. & Schroeder, B. et al. (2015)
Molecular Neurobiology, 51(1) pp. 396-405. DOI: https://doi.org/10.1007/s12035-014-8709-6
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2016 | Conference Abstract
Prion protein interactome: Identifying novel targets in rapidly progressive Alzheimer's disease
Shafiq, M.; Zafar, S.; Younas, N.; Schmitz, M.; Ferrer, I. & Zerr, I. (2016)
Prion, 10
Philadelphia: Taylor & Francis Inc.
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2016 | Conference Abstract
Genetic prion diseases
Zerr, I.; Schmitz, M.; Zafar, S. & Llorens, F. (2016)
Prion, 10
Philadelphia: Taylor & Francis Inc.
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2016 | Conference Abstract
Early response of Cofilin1 pathway in Creutzfeldt Jakob disease
Younas, N.; Zafar, S.; Shafiq, M.; Tahir, W.; Schmitz, M.; Ferrer, I. & Andreoletti, O. et al. (2016)
Prion, 10 pp. S102-S103.
Philadelphia: Taylor & Francis Inc.
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2016 | Journal Article |
Regulation of human cerebrospinal fluid malate dehydrogenase 1 in sporadic Creutzfeldt-Jakob disease patients
Schmitz, M.; Llorens, F.; Pracht, A.; Thom, T.; Correia, A. ; Zafar, S. & Ferrer, I. et al. (2016)
Aging, 8(11) pp. 2927-2935. DOI: https://doi.org/10.18632/aging.101101
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2016 | Journal Article |
Application of an in vitro-amplification assay as a novel pre-screening test for compounds inhibiting the aggregation of prion protein scrapie
Schmitz, M.; Cramm, M.; Llorens, F.; Candelise, N. ; Mueller-Cramm, D.; Varges, D. A. & Schulz-Schaeffer, W. J. et al. (2016)
Scientific Reports, 6 art. 28711. DOI: https://doi.org/10.1038/srep28711
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2017 | Journal Article
Strain-Specific Altered Regulatory Response of Rab7a and Tau in Creutzfeldt-Jakob Disease and Alzheimer's Disease
Zafar, S.; Younas, N.; Correia, S. ; Shafiq, M.; Tahir, W.; Schmitz, M. & Ferrer, I. et al. (2017)
Molecular Neurobiology, 54(1) pp. 697-709. DOI: https://doi.org/10.1007/s12035-016-9694-8
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2017 | Journal Article |
Dementia with Lewy Bodies: Molecular Pathology in the Frontal Cortex in Typical and Rapidly Progressive Forms.
Garcia-Esparcia, P.; López-González, I.; Grau-Rivera, O.; García-Garrido, M. F.; Konetti, A.; Llorens, F. & Zafar, S. et al. (2017)
Frontiers in neurology, 8 art. 89. DOI: https://doi.org/10.3389/fneur.2017.00089
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2017 | Journal Article |
Cellular prion protein mediates early apoptotic proteome alternation and phospho-modification in human neuroblastoma cells
Zafar, S.; Behrens, C.; Dihazi, H.; Schmitz, M.; Zerr, I.; Schulz-Schaeffer, W. J. & Ramljak, S. et al. (2017)
Cell Death and Disease, 8 art. e2557. DOI: https://doi.org/10.1038/cddis.2016.384
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2018 | Book Chapter
Cerebrospinal fluid in Creutzfeldt–Jakob disease
Zerr, I.; Zafar, S.; Schmitz, M.& Llorens, F. (2018)
In: Cerebrospinal Fluid in Neurologic Disorders pp. 115-124. Elsevier. DOI: https://doi.org/10.1016/B978-0-12-804279-3.00008-3
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2019 | Book Chapter
Therapies for prion diseases
Zafar, S.; Noor, A.& Zerr, I. (2019)
In: Psychopharmacology of Neurologic Disease pp. 47-58. Elsevier. DOI: https://doi.org/10.1016/B978-0-444-64012-3.00004-6
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2021 | Journal Article |
Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease
Cheng, L.; Quek, C.; Li, X.; Bellingham, S. A.; Ellett, L. J.; Shambrook, M. & Zafar, S. et al. (2021)
Communications Biology, 4(1). DOI: https://doi.org/10.1038/s42003-021-01868-x
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2021 | Journal Article | Research Paper |
Prion protein oligomers cause neuronal cytoskeletal damage in rapidly progressive Alzheimer’s disease
Shafiq, M.; Zafar, S.; Younas, N.; Noor, A.; Puig, B.; Altmeppen, H. C. & Schmitz, M. et al. (2021)
Molecular Neurodegeneration, 16(1) art. 11. DOI: https://doi.org/10.1186/s13024-021-00422-x
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2021 | Journal Article | Research Paper |
Cellular Prion Protein Mediates α‐Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo
Thom, T.; Schmitz, M.; Fischer, A.; Correia, A.; Correia, S.; Llorens, F. & Pique, A. et al. (2021)
Movement Disorders, 37(1) art. mds.28774. DOI: https://doi.org/10.1002/mds.28774
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2021 | Journal Article |
Molecular Profiles of Amyloid-β Proteoforms in Typical and Rapidly Progressive Alzheimer’s Disease
Noor, A.; Zafar, S.; Shafiq, M.; Younas, N.; Siegert, A.; Mann, F. A. & Kruss, S. et al. (2021)
Molecular Neurobiology, 59(1) pp. 17-34. DOI: https://doi.org/10.1007/s12035-021-02566-9
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2022 | Journal Article |
SWATH Mass Spectrometry-Based CSF Proteome Profile of GBA-Linked Parkinson’s Disease Patients
Zafar, S.; Noor, A.; Younas, N.; Shafiq, M.; Schmitz, M.; Wurster, I. & Brockmann, K. et al. (2022)
International Journal of Molecular Sciences, 23(22) pp. 14166. DOI: https://doi.org/10.3390/ijms232214166
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2023 | Journal Article
The Role of Tau Proteoforms in Health and Disease
Waheed, Z.; Choudhary, J.; Jatala, F. H.; Fatimah, F.; Noor, A.; Zerr, I. & Zafar, S. (2023)
Molecular Neurobiology,. DOI: https://doi.org/10.1007/s12035-023-03387-8
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2023 | Journal Article
Genetic Variants Associated with the Age of Onset Identified by Whole-Exome Sequencing in Fatal Familial Insomnia
Thüne, K.; Schmitz, M.; Wiedenhöft, J.; Shomroni, O.; Göbel, S.; Bunck, T. & Younas, N. et al. (2023)
Cells, 12(16) pp. 2053. DOI: https://doi.org/10.3390/cells12162053
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2023 | Journal Article |
Differential interactome mapping of aggregation prone/prion-like proteins under stress: novel links to stress granule biology
Younas, N. ; Zafar, S.; Saleem, T.; Fernandez Flores, L. C.; Younas, A.; Schmitz, M. & Zerr, I. (2023)
Cell & Bioscience, 13(1). DOI: https://doi.org/10.1186/s13578-023-01164-7
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2023 | Journal Article |
α-Synuclein conformers reveal link to clinical heterogeneity of α-synucleinopathies
Schmitz, M. ; Candelise, N.; Canaslan, S.; Altmeppen, H. C.; Matschke, J.; Glatzel, M. & Younas, N. et al. (2023)
Translational Neurodegeneration, 12(1) art. 12. DOI: https://doi.org/10.1186/s40035-023-00342-4
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