Author Spieth, Lena
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2017 | Journal Article |
Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model
Berghoff, S. A.; Düking, T.; Spieth, L.; Winchenbach, J.; Stumpf, S. K.; Gerndt, N. & Kusch, K. et al. (2017)
Acta Neuropathologica Communications, 5(1). DOI: https://doi.org/10.1186/s40478-017-0497-6
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2019 | Journal Article |
Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus-Merzbacher disease
Stumpf, S. K.; Berghoff, S. A.; Trevisiol, A. ; Spieth, L.; Düking, T.; Schneider, L. V. & Schlaphoff, L. et al. (2019)
Acta Neuropathologica, 138(1) pp. 147-161. DOI: https://doi.org/10.1007/s00401-019-01985-2
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2019 | Journal Article | Erratum |
Correction to: Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus–Merzbacher disease
Stumpf, S. K.; Berghoff, S. A.; Trevisiol, A.; Spieth, L.; Düking, T.; Schneider, L. V. & Schlaphoff, L. et al. (2019)
Acta Neuropathologica, 138(4) pp. 673-674. DOI: https://doi.org/10.1007/s00401-019-02064-2
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2020 | Journal Article | Research Paper
Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis
Berghoff, S. A.; Spieth, L.; Sun, T.; Hosang, L. ; Schlaphoff, L.; Depp, C. & Düking, T. et al. (2020)
Nature Neuroscience, 24(1) pp. 47-60. DOI: https://doi.org/10.1038/s41593-020-00757-6
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2021 | Journal Article
Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice
Berghoff, S. A.; Spieth, L.; Sun, T.; Hosang, L.; Depp, C.; Sasmita, A. O. & Vasileva, M. H. et al. (2021)
Cell Reports, 37(4) art. S2211124721013590. DOI: https://doi.org/10.1016/j.celrep.2021.109889
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2021 | Journal Article
Anesthesia triggers drug delivery to experimental glioma in mice by hijacking caveolar transport
Spieth, L.; Berghoff, S. A; Stumpf, S. K; Winchenbach, J.; Michaelis, T.; Watanabe, T. & Gerndt, N. et al. (2021)
Neuro-Oncology Advances, 3(1) art. vdab140. DOI: https://doi.org/10.1093/noajnl/vdab140
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2021 | Journal Article | Research Paper |
NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance
Arinrad, S.; Wilke, J. B. H.; Seelbach, A.; Doeren, J.; Hindermann, M.; Butt, U. J. & Steixner-Kumar, A. A. et al. (2021)
Molecular Psychiatry,. DOI: https://doi.org/10.1038/s41380-021-01392-8
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2022 | Journal Article
Local cholesterol metabolism orchestrates remyelination
Berghoff, S. A.; Spieth, L. & Saher, G. (2022)
Trends in Neurosciences, 45(4) pp. 272-283. DOI: https://doi.org/10.1016/j.tins.2022.01.001
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2022 | Journal Article |
Ketogenic diet uncovers differential metabolic plasticity of brain cells
Düking, T.; Spieth, L.; Berghoff, S. A.; Piepkorn, L.; Schmidke, A. M.; Mitkovski, M. & Kannaiyan, N. et al. (2022)
Science Advances, 8(37) art. eabo7639. DOI: https://doi.org/10.1126/sciadv.abo7639
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2023 | Preprint
Oligodendrocytes and neurons contribute to amyloid-β deposition in Alzheimer’s disease
Sasmita, A. O.; Depp, C.; Nazarenko, T.; Sun, T.; Siems, S. B.; Yu, X.& Boehler, C. et al. (2023). DOI: https://doi.org/10.1101/2023.12.11.570514
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2023 | Journal Article |
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease
Depp, C.; Sun, T.; Sasmita, A. O.; Spieth, L.; Berghoff, S. A.; Nazarenko, T. & Overhoff, K. et al. (2023)
Nature, 618(7964) pp. 349-357. DOI: https://doi.org/10.1038/s41586-023-06120-6
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