Author Konstantinides, Stavros
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2002 | Journal Article
Heparin plus alteplase compared with heparin alone in patients with submassive pulmonary embolism
Konstantinides, S.; Geibel, A.; Heusel, G.; Heinrich, F. & Kasper, W. (2002)
New England Journal of Medicine, 347(15) pp. 1143-1150. DOI: https://doi.org/10.1056/NEJMoa021274
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2002 | Journal Article | Research Paper
Different mechanisms of increased luminal stenosis after arterial injury in mice deficient for urokinase- or tissue-type plasminogen activator
Schäfer, K. ; Konstantinides, S.; Riedel, C. ; Thinnes, T.; Muller, K.; Dellas, C. & Hasenfuß, G. et al. (2002)
Circulation, 106(14) pp. 1847-1852. DOI: https://doi.org/10.1161/01.CIR.0000031162.80988.2B
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2004 | Journal Article
Should Thrombolytic Therapy Be Used in Patients with Pulmonary Embolism?
Konstantinides, S. (2004)
American Journal of Cardiovascular Drugs, 4(2) pp. 69-74. DOI: https://doi.org/10.2165/00129784-200404020-00001
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2004 | Journal Article | Research Paper
Acute cor pulmonale in pulmonary embolism. An important prognostic factor and a critical parameter for the choice of the therapeutic strategy
Konstantinides, S. & Hasenfuß, G. (2004)
Der Internist, 45(10) pp. 1155-1162. DOI: https://doi.org/10.1007/s00108-004-1267-7
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2005 | Journal Article |
Rosuvastatin exerts favourable effects on thrombosis and neointimal growth in a mouse model of endothelial injury
Schäfer, K.; Kaiser, K. & Konstantinides, S. (2005)
Thrombosis and Haemostasis, 93(1) pp. 145-152. DOI: https://doi.org/10.1160/TH04-07-0415
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2006 | Journal Article | Research Paper
Successful silencing of plasminogen activator inhibitor-I in human vascular enclothelial cells using small interfering RNA
Hecke, A.; Brooks, H.; Meryet-Figuiere, M.; Minne, S.; Konstantinides, S.; Hasenfuß, G. & Lebleu, B. et al. (2006)
Thrombosis and Haemostasis, 95(5) pp. 857-864. DOI: https://doi.org/10.1160/TH05-08-0569
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2007 | Journal Article | Research Paper
Heart-type fatty acid-binding protein permits early risk stratification of pulmonary embolism
Puls, M. ; Dellas, C. ; Lankeit, M. ; Olschewski, M.; Binder, L. ; Geibel, A. & Reiner, C. et al. (2007)
European heart journal, 28(2) pp. 224-229. DOI: https://doi.org/10.1093/eurheartj/ehl405
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2008 | Journal Article | Research Paper |
Absence of leptin resistance in platelets from morbidly obese individuals may contribute to the increased thrombosis risk in obesity
Dellas, C. ; Schaefer, K. ; Rohm, I.; Lankeit, M. ; Ellrott, T. ; Faustin, V. & Riggert, J. et al. (2008)
Thrombosis and Haemostasis, 100(6) pp. 1123-1129. DOI: https://doi.org/10.1160/TH08-05-0314
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2008 | Journal Article | Research Paper
Leptin Enhances the Recruitment of Endothelial Progenitor Cells Into Neointimal Lesions After Vascular Injury by Promoting Integrin-Mediated Adhesion
Schroeter, M. R. ; Leifheit, M.; Sudholt, P.; Heida, N.-M.; Dellas, C. ; Rohm, I. & Alves, F. et al. (2008)
Circulation Research, 103(5) pp. 536-544. DOI: https://doi.org/10.1161/CIRCRESAHA.107.169375
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2010 | Journal Article | Research Paper
Leptin Enhances the Potency of Circulating Angiogenic Cells Via Src Kinase and Integrin alpha v beta 5 Implications for Angiogenesis in Human Obesity
Heida, N.-M.; Leifheit-Nestler, M. ; Schroeter, M. R. ; Mueller, J.-P.; Cheng, I.-F. ; Henkel, S. & Limbourg, A. et al. (2010)
Arteriosclerosis, Thrombosis, and Vascular Biology, 30(2) pp. 200-206. DOI: https://doi.org/10.1161/ATVBAHA.109.192807
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2010 | Journal Article | Research Paper |
Elevated Heart-Type Fatty Acid-Binding Protein Levels on Admission Predict an Adverse Outcome in Normotensive Patients With Acute Pulmonary Embolism
Dellas, C. ; Puls, M. ; Lankeit, M. ; Schaefer, K. ; Cuny, M.; Berner, M. & Hasenfuß, G. et al. (2010)
Journal of the American College of Cardiology, 55(19) pp. 2150-2157. DOI: https://doi.org/10.1016/j.jacc.2009.10.078
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2010 | Journal Article | Research Paper |
Effects of Obesity and Weight Loss on the Functional Properties of Early Outgrowth Endothelial Progenitor Cells
Heida, N.-M.; Mueller, J.-P.; Cheng, I.-F. ; Leifheit-Nestler, M. ; Faustin, V.; Riggert, J. & Hasenfuß, G. et al. (2010)
Journal of the American College of Cardiology, 55(4) pp. 357-367. DOI: https://doi.org/10.1016/j.jacc.2009.09.031
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2010 | Journal Article | Research Paper
Highly sensitive troponin T assay in normotensive patients with acute pulmonary embolism
Lankeit, M. ; Friesen, D.; Aschoff, J.; Dellas, C. ; Hasenfuß, G. ; Katus, H. A. & Konstantinides, S. et al. (2010)
European heart journal, 31(15) pp. 1836-1844. DOI: https://doi.org/10.1093/eurheartj/ehq234
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2010 | Journal Article | Research Paper
Overexpression of Integrin beta 5 Enhances the Paracrine Properties of Circulating Angiogenic Cells via Src Kinase-Mediated Activation of STAT3
Leifheit-Nestler, M. ; Conrad, G.; Heida, N.-M.; Limbourg, A.; Limbourg, F. P.; Seidler, T. & Schroeter, M. R. et al. (2010)
Arteriosclerosis, Thrombosis, and Vascular Biology, 30(7) pp. 1398-U339. DOI: https://doi.org/10.1161/ATVBAHA.110.206086
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2011 | Journal Article | Research Paper
Effect of smoking cessation on the number and adhesive properties of early outgrowth endothelial progenitor cells
Puls, M. ; Schroeter, M. R. ; Steier, J.; Stijohann, L.; Hasenfuß, G. ; Konstantinides, S. & Schaefer, K. (2011)
International Journal of Cardiology, 152(1) pp. 61-69. DOI: https://doi.org/10.1016/j.ijcard.2010.07.007
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2011 | Journal Article | Research Paper |
Predictive Value of the High-Sensitivity Troponin T Assay and the Simplified Pulmonary Embolism Severity Index in Hemodynamically Stable Patients With Acute Pulmonary Embolism A Prospective Validation Study
Lankeit, M. ; Jimenez, D.; Kostrubiec, M.; Dellas, C. ; Hasenfuß, G. ; Pruszczyk, P. & Konstantinides, S. (2011)
Circulation, 124(24) pp. 2716-U300. DOI: https://doi.org/10.1161/CIRCULATIONAHA.111.051177
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2012 | Journal Article | Research Paper
Leptin promotes the mobilization of vascular progenitor cells and neovascularization by NOX2-mediated activation of MMP9
Schroeter, M. R. ; Stein, S.; Heida, N.-M.; Leifheit-Nestler, M. ; Cheng, I.-F. ; Gogiraju, R. & Christiansen, H. et al. (2012)
Cardiovascular Research, 93(1) pp. 170-180. DOI: https://doi.org/10.1093/cvr/cvr275
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2013 | Journal Article | Research Paper
Circulating Regulatory T Cells Are Reduced in Obesity and May Identify Subjects at Increased Metabolic and Cardiovascular Risk
Wagner, N.-M.; Brandhorst, G.; Czepluch, F. S. ; Lankeit, M. ; Eberle, C.; Herzberg, S. & Faustin, V. et al. (2013)
Obesity, 21(3) pp. 461-468. DOI: https://doi.org/10.1002/oby.20087
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2013 | Journal Article | Research Paper |
A simple score for rapid risk assessment of non-high-risk pulmonary embolism
Lankeit, M. ; Friesen, D.; Schaefer, K. ; Hasenfuß, G. ; Konstantinides, S. & Dellas, C. (2013)
Clinical Research in Cardiology, 102(1) pp. 73-80. DOI: https://doi.org/10.1007/s00392-012-0498-1
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2013 | Journal Article | Research Paper
BMI-independent inverse relationship of plasma leptin levels with outcome in patients with acute pulmonary embolism
Dellas, C. ; Lankeit, M. ; Reiner, C.; Schaefer, K. ; Hasenfuß, G. & Konstantinides, S. (2013)
International Journal of Obesity, 37(2) pp. 204-210. DOI: https://doi.org/10.1038/ijo.2012.36
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2013 | Journal Article | Research Paper
The predictive value of heart-type fatty acid-binding protein is independent from symptom duration in normotensive patients with pulmonary embolism
Lankeit, M. ; Dellas, C. ; Benz, V.; Hasenfuß, G. & Konstantinides, S. (2013)
Thrombosis Research, 132(5) pp. 543-547. DOI: https://doi.org/10.1016/j.thromres.2013.09.022
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2013 | Journal Article | Research Paper |
Importance of leptin signaling and signal transducer and activator of transcription-3 activation in mediating the cardiac hypertrophy associated with obesity
Leifheit-Nestler, M. ; Wagner, N.-M.; Gogiraju, R.; Didie, M. ; Konstantinides, S.; Hasenfuß, G. & Schaefer, K. (2013)
Journal of Translational Medicine, 11 art. 170. DOI: https://doi.org/10.1186/1479-5876-11-170
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2013 | Journal Article | Research Paper
Leptin promotes neointima formation and smooth muscle cell proliferation via NADPH oxidase activation and signalling in caveolin-rich microdomains
Schroeter, M. R. ; Leifheit-Nestler, M. ; Hubert, A.; Schumann, B.; Glueckermann, R.; Eschholz, N. & Krueger, N. et al. (2013)
Cardiovascular Research, 99(3) pp. 555-565. DOI: https://doi.org/10.1093/cvr/cvt126
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2014 | Journal Article
Mechanisms Linking Leptin to Arterial and Venous Thrombosis: Potential Pharmacological Targets
Schafer, K. & Konstantinides, S. (2014)
Current Pharmaceutical Design, 20(4) pp. 635-640. DOI: https://doi.org/10.2174/13816128113199990021
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2014 | Journal Article | Research Paper
A novel H-FABP assay and a fast prognostic score for risk assessment of normotensive pulmonary embolism
Dellas, C. ; Tschepe, M.; Seeber, V.; Zwiener, I.; Kuhnert, K.; Schaefer, K. & Hasenfuß, G. et al. (2014)
Thrombosis and Haemostasis, 111(5) pp. 996-1003. DOI: https://doi.org/10.1160/TH13-08-0663
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2014 | Journal Article | Research Paper
Validation of N-terminal pro-brain natriuretic peptide cut-off values for risk stratification of pulmonary embolism
Lankeit, M. ; Jimenez, D.; Kostrubiec, M.; Dellas, C. ; Kuhnert, K.; Hasenfuß, G. & Pruszczyk, P. et al. (2014)
European Respiratory Journal, 43(6) pp. 1669-1677. DOI: https://doi.org/10.1183/09031936.00211613
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2015 | Journal Article | Research Paper
External validation of a simple non-invasive algorithm to rule out chronic thromboembolic pulmonary hypertension after acute pulmonary embolism
Klok, F. A.; Tesche, C.; Rappold, L.; Dellas, C. ; Hasenfuß, G. ; Huisman, M. V. & Konstantinides, S. et al. (2015)
Thrombosis Research, 135(5) pp. 796-801. DOI: https://doi.org/10.1016/j.thromres.2014.12.009
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2015 | Journal Article | Research Paper
Age-adjusted high-sensitivity troponin cut-off value for risk stratification of pulmonary embolism
Kaeberich, A.; Seeber, V.; Jimenez, D.; Kostrubiec, M.; Dellas, C. ; Hasenfuß, G. & Giannitsis, E. et al. (2015)
European Respiratory Journal, 45(5) pp. 1323-1331. DOI: https://doi.org/10.1183/09031936.00174514
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2015 | Journal Article | Research Paper
Risk stratification of normotensive pulmonary embolism: prognostic impact of copeptin
Hellenkamp, K. ; Schwung, J.; Rossmann, H.; Kaeberich, A.; Wachter, R. ; Hasenfuß, G. & Konstantinides, S. et al. (2015)
European Respiratory Journal, 46(6) pp. 1701-1710. DOI: https://doi.org/10.1183/13993003.00857-2015
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2016 | Journal Article
Pulmonary hypertension in heart failure with preserved ejection fraction: a plea for proper phenotyping and further research†
Hoeper, M. M.; Lam, C. S.; Vachiery, J.-L.; Bauersachs, J.; Gerges, C.; Lang, I. M. & Bonderman, D. et al. (2016)
European Heart Journal, pp. ehw597. DOI: https://doi.org/10.1093/eurheartj/ehw597
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2016 | Journal Article | Research Paper
Performance of five different bleeding-prediction scores in patients with acute pulmonary embolism
Klok, F. A.; Niemann, C.; Dellas, C. ; Hasenfuß, G. ; Konstantinides, S. & Lankeit, M. (2016)
Journal of Thrombosis and Thrombolysis, 41(2) pp. 312-320. DOI: https://doi.org/10.1007/s11239-015-1239-x
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2016 | Journal Article | Research Paper
Comparison of risk assessment strategies for not-high-risk pulmonary embolism
Hobohm, L.; Hellenkamp, K. ; Hasenfuß, G. ; Muenzel, T.; Konstantinides, S. & Lankeit, M. (2016)
European Respiratory Journal, 47(4) pp. 1170-1178. DOI: https://doi.org/10.1183/13993003.01605-2015
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2016 | Journal Article | Research Paper
Derivation of a clinical prediction score for chronic thromboembolic pulmonary hypertension after acute pulmonary embolism
Klok, F. A.; Dzikowska-Diduch, O.; Kostrubiec, M.; Vliegen, H. W.; Pruszczyk, P.; Hasenfuß, G. & Huisman, M. V. et al. (2016)
Journal of Thrombosis and Haemostasis, 14(1) pp. 121-128. DOI: https://doi.org/10.1111/jth.13175
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2017 | Journal Article
From thrombosis to fibrosis in chronic thromboembolic pulmonary hypertension
Bochenek, M.; Rosinus, N.; Lankeit, M. ; Hobohm, L.; Bremmer, F. ; Schütz, E. & Klok, F. et al. (2017)
Thrombosis and Haemostasis, 117(4) pp. 769-783. DOI: https://doi.org/10.1160/TH16-10-0790
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2018 | Journal Article
Prognostic impact of copeptin in pulmonary embolism: a multicentre validation study
Hellenkamp, K. ; Pruszczyk, P.; Jiménez, D.; Wyzgał, A.; Barrios, D.; Ciurzyński, M. & Morillo, R. et al. (2018)
European Respiratory Journal, 51(4) pp. 1702037. DOI: https://doi.org/10.1183/13993003.02037-2017
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2018 | Journal Article
The Prognostic Value of Renal Function in Acute Pulmonary Embolism—A Multi-Centre Cohort Study
Kostrubiec, M.; Pływaczewska, M.; Jiménez, D.; Lankeit, M. ; Ciurzynski, M.; Konstantinides, S. & Pruszczyk, P. (2018)
Thrombosis and Haemostasis, 119(01) pp. 140-148. DOI: https://doi.org/10.1055/s-0038-1676522
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2019 | Journal Article | Research Paper
Endothelial Leptin Receptor Deletion Promotes Cardiac Autophagy and Angiogenesis Following Pressure Overload by Suppressing Akt/mTOR Signaling
Gogiraju, R.; Hubert, A.; Fahrer, J.; Straub, B. K.; Brandt, M.; Wenzel, P. & Münzel, T. et al. (2019)
Circulation: Heart Failure, 12(1). DOI: https://doi.org/10.1161/CIRCHEARTFAILURE.118.005622
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2020 | Journal Article
Kommentar zu den Leitlinien (2019) der European Society of Cardiology zum Management der akuten Lungenembolie: Unter Mitwirkung der European Respiratory Society (ERS)
Konstantinides, S.; Lankeit, M. ; Erbel, C. & Tiefenbacher, C. (2020)
Der Kardiologe, 14(4) pp. 248-255. DOI: https://doi.org/10.1007/s12181-020-00389-x
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2021 | Journal Article
Assessment of pulmonary embolism severity and the risk of early death
Pruszczyk, P.; Skowrońska, M.; Ciurzyński, M.; Kurnicka, K.; Lankei, M. & Konstantinides, S. (2021)
Polish Archives of Internal Medicine,. DOI: https://doi.org/10.20452/pamw.16134
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2022 | Journal Article
Impact of thyroid dysfunction on short-term outcomes and long-term mortality in patients with pulmonary embolism
Pohl, K. R.; Hobohm, L.; Krieg, V. J.; Sentler, C.; Rogge, N. I.; Steimke, L. & Ebner, M. et al. (2022)
Thrombosis Research, 211 pp. 70-78. DOI: https://doi.org/10.1016/j.thromres.2022.01.014
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2023 | Journal Article
Long-term mortality in patients with pulmonary embolism: results in a single-center registry
Eckelt, J.; Hobohm, L.; Merten, M. C.; Pagel, C. F.; Eggers, A.-S.; Lerchbaumer, M. H. & Stangl, K. et al. (2023)
Research and Practice in Thrombosis and Haemostasis, 7(5) art. 100280. DOI: https://doi.org/10.1016/j.rpth.2023.100280
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